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Pathogen
Any pathogen
Acinetobacter baumannii ATCC 17978
Campylobacter jejuni subsp. jejuni 81-176
Escherichia coli CFT073
Escherichia coli M12
Escherichia coli O157:H7 str. EDL933
Haemophilus influenzae Rd KW20
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Mycobacterium avium subsp. paratuberculosis K10
Porphyromonas gingivalis ATCC 33277
Salmonella enterica Serovar Typhimurium SL1344
Salmonella enterica Serovar Typhimurium ST4 74
Serratia marcescens Strain UMH9
Streptococcus pyogenes M1 5448
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio parahaemolyticus RIMD 2210633
Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):
Download Table
Pathogen
Locus
Protein
UniProt
Gene
Length
Product
p-Value
Fitness z-Score
Precise fitness z-Score
Mycobacterium avium subsp. paratuberculosis K10
MAP_0578
AAS02895.1
Q743K7
263 aa
hypothetical protein
0.012
○○○○○ 2.19
2.19261898351986
Mycobacterium avium subsp. paratuberculosis K10
MAP_3518c
AAS06068.1
Q73U50
341 aa
hypothetical protein
0.012
○○○○○ 2.19
2.19479570014213
Mycobacterium avium subsp. paratuberculosis K10
MAP_3688
AAS06238.1
Q73TN0
lpqI
388 aa
LpqI
0.012
○○○○○ 2.19
2.19483336641638
Mycobacterium avium subsp. paratuberculosis K10
MAP_0167
AAS02484.1
Q745F4
613 aa
hypothetical protein
0.012
○○○○○ 2.2
2.19632175302766
Haemophilus influenzae Rd KW20
HI_0743
NP_438902.1
P44853
secB
169 aa
preprotein translocase subunit SecB
0.03
○○○○○ 2.2
2.19661519660036
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1353
WP_002856278.1
A0A0H3PA10
ceuD
251 aa
ABC transporter ATP-binding protein
0.018
○○○○○ 2.2
2.19910403193
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0685
WP_002869349.1
A0A0H3PA12
351 aa
MFS transporter
0.018
○○○○○ 2.2
2.19982451574
Mycobacterium avium subsp. paratuberculosis K10
MAP_2499
AAS04816.1
Q73X11
585 aa
hypothetical protein
0.012
○○○○○ 2.2
2.20459745591464
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0051
WP_002868981.1
A0A0H3PCL7
nrdA
789 aa
ribonucleoside-diphosphate reductase subunit alpha
0.018
○○○○○ 2.21
2.20598999208
Escherichia coli M12
CO715_21370
ATI08051.1
237 aa
hypothetical protein
0.002
○○○○○ 2.21
2.20798263401017
Escherichia coli M12
CO715_16765
ATI07224.1
354 aa
proline/glycine betaine ABC transporter permease ProW
3.9e-15
○○○○○ 2.21
2.21048638618115
Escherichia coli M12
CO715_01360
ATI04499.1
102 aa
RNA-binding protein Hfq
2.7e-5
○○○○○ 2.21
2.21194690828089
Streptococcus pyogenes M1 5448
SP5448_06900
WP_002985455.1
230 aa
cell division ATP-binding protein FtsE
0.028
○○○○○ 2.21
2.21378139672421
Escherichia coli M12
CO715_20495
ATI07893.1
101 aa
chaperone modulatory protein CbpM
1.5e-9
○○○○○ 2.22
2.21987545682235
Mycobacterium avium subsp. paratuberculosis K10
MAP_3578
AAS06128.1
Q73TZ0
446 aa
hypothetical protein
0.011
○○○○○ 2.22
2.22122088918178
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0107
WP_002851763.1
A0A0H3PAB0
343 aa
Cj0069 family protein
0.018
○○○○○ 2.22
2.22318985225
Vibrio cholerae O1 biovar El Tor str. N16961
VC_2135
NP_231766.1
Q9KQ67
479 aa
Fis family transcriptional regulator
1.3e-5
○○○○○ 2.22
2.22357118529495
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1208
AIK79831.1
225 aa
PKHD-type hydroxylase
<1e-323
○○○○○ 2.22
2.22390635145205
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_5034
AIK83560.1
384 aa
UDP-galactopyranose mutase
0.00098
○○○○○ 2.22
2.22499219334315
Haemophilus influenzae Rd KW20
HI_0262
NP_438431.1
P44600
hxuC
723 aa
heme-hemopexin utilization protein C
0.028
○○○○○ 2.23
2.22605655195235
Mycobacterium avium subsp. paratuberculosis K10
MAP_2015
AAS04332.1
Q73YE1
435 aa
hypothetical protein
0.011
○○○○○ 2.23
2.22846592183997
Mycobacterium avium subsp. paratuberculosis K10
MAP_1400
AAS03717.1
Q740F1
61 aa
hypothetical protein
0.011
○○○○○ 2.23
2.22989377081959
Mycobacterium avium subsp. paratuberculosis K10
MAP_0651
AAS02968.1
Q743D4
phoS2
365 aa
PhoS2_1
0.011
○○○○○ 2.24
2.23571590201657
Mycobacterium avium subsp. paratuberculosis K10
MAP_0765
AAS03082.1
Q742S0
576 aa
hypothetical protein
0.011
○○○○○ 2.24
2.23690991832895
Mycobacterium avium subsp. paratuberculosis K10
MAP_3680c
AAS06230.1
Q73TN8
389 aa
hypothetical protein
0.011
○○○○○ 2.24
2.23912973217368
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0581
WP_002855246.1
A0A0H3PAB4
265 aa
amidohydrolase
0.017
○○○○○ 2.24
2.24037695773
Mycobacterium avium subsp. paratuberculosis K10
MAP_1908
AAS04225.1
Q73YP7
200 aa
hypothetical protein
0.011
○○○○○ 2.24
2.24073196644092
Mycobacterium avium subsp. paratuberculosis K10
MAP_0161
AAS02478.1
Q9K548
esxC
95 aa
hypothetical protein
0.011
○○○○○ 2.24
2.24170116832501
Mycobacterium avium subsp. paratuberculosis K10
MAP_0965c
AAS03282.1
Q741X2
190 aa
hypothetical protein
0.011
○○○○○ 2.24
2.24445091590109
Mycobacterium avium subsp. paratuberculosis K10
MAP_1668c
AAS03985.1
Q73ZD5
katG
748 aa
KatG
0.01
○○○○○ 2.25
2.24637556605693
Mycobacterium avium subsp. paratuberculosis K10
MAP_4010c
AAS06560.1
Q73SR3
720 aa
hypothetical protein
0.01
○○○○○ 2.25
2.24667624100695
Mycobacterium avium subsp. paratuberculosis K10
MAP_2532
AAS04849.1
Q73WX8
223 aa
hypothetical protein
0.01
○○○○○ 2.25
2.24721390375472
Mycobacterium avium subsp. paratuberculosis K10
MAP_4102c
AAS06652.1
Q73SH2
echA3
430 aa
EchA3
0.01
○○○○○ 2.25
2.25005733910859
Streptococcus pyogenes M1 5448
SP5448_05860
WP_010922231.1
415 aa
hypothetical protein
0.0097
○○○○○ 2.25
2.25031218365067
Mycobacterium avium subsp. paratuberculosis K10
MAP_1127c
AAS03444.1
Q741G4
496 aa
hypothetical protein
0.01
○○○○○ 2.25
2.2507054988724
Mycobacterium avium subsp. paratuberculosis K10
MAP_4043c
AAS06593.1
Q73SN0
298 aa
hypothetical protein
0.01
○○○○○ 2.25
2.25198065253046
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_5176
AIK83697.1
70 aa
hypothetical protein
<1e-323
○○○○○ 2.25
2.25376540335648
Vibrio parahaemolyticus RIMD 2210633
VP_2857
BAC61120.1
Q87KW8
170 aa
putative periplasmic protein CpxP
0.027
○○○○○ 2.25
2.25456511433176
Mycobacterium avium subsp. paratuberculosis K10
MAP_3556
AAS06106.1
Q73U12
339 aa
hypothetical protein
0.01
○○○○○ 2.26
2.25575921913061
Vibrio parahaemolyticus RIMD 2210633
VPA_1375
BAC62718.1
Q87GE1
31 aa
hypothetical protein
0.038
○○○○○ 2.26
2.25695375749568
Escherichia coli O157:H7 str. EDL933
Z3955
AAG57765.1
335 aa
putative enzyme
0.014
○○○○○ 2.26
2.25766544102092
Escherichia coli M12
CO715_15400
ATI08826.1
166 aa
periplasmic protein CpxP
2.0e-36
○○○○○ 2.26
2.25889226148689
Streptococcus pyogenes M1 5448
SP5448_04010
WP_010922418.1
475 aa
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
0.033
○○○○○ 2.26
2.25896421213326
Mycobacterium avium subsp. paratuberculosis K10
MAP_4284
AAS06834.1
Q73RZ4
ctpA
742 aa
CtpA
0.01
○○○○○ 2.26
2.25916713425114
Mycobacterium avium subsp. paratuberculosis K10
MAP_2160c
AAS04477.1
Q73XZ8
phoH
352 aa
PhoH
0.01
○○○○○ 2.27
2.26589373200721
Streptococcus pyogenes M1 5448
SP5448_06655
WP_002985238.1
502 aa
F0F1 ATP synthase subunit alpha
0.024
○○○○○ 2.27
2.26761624061584
Mycobacterium avium subsp. paratuberculosis K10
MAP_0190
AAS02507.1
Q745J5
glpQ1
272 aa
GlpQ1
0.0099
○○○○○ 2.27
2.26998412606374
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1090
AIK79713.1
361 aa
type VI secretion system protein
<1e-323
○○○○○ 2.27
2.27084505012517
Mycobacterium avium subsp. paratuberculosis K10
MAP_2287
AAS04604.1
Q73XM2
pepD
863 aa
PepD
0.0099
○○○○○ 2.27
2.27114054141381
Mycobacterium avium subsp. paratuberculosis K10
MAP_0072c
AAS02389.1
Q744X3
295 aa
hypothetical protein
0.0098
○○○○○ 2.27
2.27443813473545
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1128
WP_002855890.1
A0A0H3P9P7
429 aa
PAS domain-containing protein
0.016
○○○○○ 2.28
2.27744756072
Mycobacterium avium subsp. paratuberculosis K10
MAP_4244
AAS06794.1
Q73S32
98 aa
hypothetical protein
0.0098
○○○○○ 2.28
2.27758212625144
Serratia marcescens Strain UMH9
BVG96_19655
ASL99705.1
491 aa
ketol-acid reductoisomerase
0.0068
○○○○○ 2.28
2.27835130743555
Mycobacterium avium subsp. paratuberculosis K10
MAP_3152c
AAS05700.1
Q73V64
306 aa
hypothetical protein
0.0096
○○○○○ 2.28
2.28329082263411
Vibrio parahaemolyticus RIMD 2210633
VP_1553
BAC59816.1
Q79YY0
76 aa
bacteriophage f237 ORF3
0.026
○○○○○ 2.28
2.28377204471589
Streptococcus pyogenes M1 5448
SP5448_05630
WP_010922264.1
233 aa
noncanonical pyrimidine nucleotidase, YjjG family
0.017
○○○○○ 2.28
2.28395896108294
Mycobacterium avium subsp. paratuberculosis K10
MAP_1319
AAS03636.1
Q740N1
207 aa
hypothetical protein
0.0096
○○○○○ 2.29
2.28526373847803
Mycobacterium avium subsp. paratuberculosis K10
MAP_3053c
AAS05601.1
Q73VG1
370 aa
hypothetical protein
0.0096
○○○○○ 2.29
2.28635499406418
Mycobacterium avium subsp. paratuberculosis K10
MAP_1394c
AAS03711.1
Q740F7
amt
425 aa
Amt_1
0.0096
○○○○○ 2.29
2.2874247345921
Porphyromonas gingivalis ATCC 33277
PGN_1928
WP_012458614.1
B2RM52
248 aa
type III-B CRISPR module RAMP protein Cmr6
3.1e-14
○○○○○ 2.29
2.28835494423157
Mycobacterium avium subsp. paratuberculosis K10
MAP_1849
AAS04166.1
Q73YV6
286 aa
hypothetical protein
0.0095
○○○○○ 2.29
2.28900923681845
Mycobacterium avium subsp. paratuberculosis K10
MAP_2642
AAS04959.1
Q73WL8
349 aa
hypothetical protein
0.0095
○○○○○ 2.29
2.28928100994937
Streptococcus pyogenes M1 5448
SP5448_02810
WP_011285659.1
489 aa
hypothetical protein
0.035
○○○○○ 2.29
2.29068831656939
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1573
WP_002855909.1
Q0Q7H6
185 aa
chaperone
0.015
○○○○○ 2.3
2.29537328847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1222
AIK79845.1
252 aa
ydjC-like family protein
<1e-323
○○○○○ 2.3
2.29682143851889
Mycobacterium avium subsp. paratuberculosis K10
MAP_3116c
AAS05664.1
Q73V98
252 aa
hypothetical protein
0.0093
○○○○○ 2.3
2.29770110682328
Mycobacterium avium subsp. paratuberculosis K10
MAP_0533
AAS02850.1
Q743Q8
352 aa
hypothetical protein
0.0093
○○○○○ 2.3
2.29893379580695
Mycobacterium avium subsp. paratuberculosis K10
MAP_0223c
AAS02540.1
Q745M8
273 aa
hypothetical protein
0.0093
○○○○○ 2.3
2.30023166956997
Escherichia coli M12
CO715_07265
ATI05533.1
230 aa
two-component system response regulator TorR
0.0013
○○○○○ 2.3
2.30124740237941
Streptococcus pyogenes M1 5448
SP5448_03050
WP_010922522.1
201 aa
DUF624 domain-containing protein
0.021
○○○○○ 2.3
2.30126301804811
Mycobacterium avium subsp. paratuberculosis K10
MAP_3604
AAS06154.1
I3NIE5
mce1
434 aa
Mce1_2
0.0092
○○○○○ 2.3
2.30410724003697
Mycobacterium avium subsp. paratuberculosis K10
MAP_3775c
AAS06325.1
Q73TE3
242 aa
hypothetical protein
0.0092
○○○○○ 2.31
2.30578097636061
Acinetobacter baumannii ATCC 17978
A1S_0650
ABO11099.2
275 aa
conjugal transfer protein
2.6e-24
○○○○○ 2.31
2.30636562862053
Mycobacterium avium subsp. paratuberculosis K10
MAP_2985
AAS05302.1
Q73VM8
590 aa
hypothetical protein
0.0091
○○○○○ 2.31
2.30641479163193
Mycobacterium avium subsp. paratuberculosis K10
MAP_3411c
AAS05961.1
Q73UF7
150 aa
hypothetical protein
0.0091
○○○○○ 2.31
2.30656051089139
Mycobacterium avium subsp. paratuberculosis K10
MAP_3692c
AAS06242.1
Q73TM6
fabG4
454 aa
FabG4
0.0091
○○○○○ 2.31
2.30662731249425
Mycobacterium avium subsp. paratuberculosis K10
MAP_1387c
AAS03704.1
Q740G4
244 aa
hypothetical protein
0.0091
○○○○○ 2.31
2.30814087960773
Mycobacterium avium subsp. paratuberculosis K10
MAP_0754c
AAS03071.1
Q742T1
233 aa
hypothetical protein
0.0091
○○○○○ 2.31
2.30869658523962
Mycobacterium avium subsp. paratuberculosis K10
MAP_4152
AAS06702.1
Q73SC2
109 aa
hypothetical protein
0.0091
○○○○○ 2.31
2.30888596575676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1020
AIK79643.1
315 aa
bacterial regulatory helix-turn-helix, lysR family protein
<1e-323
○○○○○ 2.31
2.30929162941548
Escherichia coli M12
CO715_02720
ATI04745.1
205 aa
hydrogenase-4 F-S subunit
4.7e-33
○○○○○ 2.31
2.31084511903485
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1224
WP_002867371.1
A0A0H3PCW9
419 aa
competence protein
0.014
○○○○○ 2.31
2.31321174631
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1224
WP_002868860.1
A0A0H3PCW9
185 aa
DedA family protein
0.014
○○○○○ 2.31
2.31321174631
Mycobacterium avium subsp. paratuberculosis K10
MAP_1641c
AAS03958.1
Q73ZG2
107 aa
hypothetical protein
0.009
○○○○○ 2.31
2.31383879554363
Mycobacterium avium subsp. paratuberculosis K10
MAP_1382c
AAS03699.1
Q740G9
368 aa
hypothetical protein
0.009
○○○○○ 2.31
2.31440214371107
Vibrio cholerae O1 biovar El Tor str. N16961
VC_1416
NP_231059.1
Q9KS45
vgrG1
1163 aa
VgrG protein
0.0055
○○○○○ 2.32
2.31949974610024
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1359
WP_002869320.1
A0A0H3P9Q2
nrfA
610 aa
ammonia-forming cytochrome c nitrite reductase subunit c552
0.014
○○○○○ 2.32
2.32015673409
Vibrio parahaemolyticus RIMD 2210633
VP_2791
BAC61054.1
Q87L25
70 aa
conserved hypothetical protein
0.023
○○○○○ 2.32
2.32137191952163
Vibrio parahaemolyticus RIMD 2210633
VPA_0905
BAC62248.1
Q87HQ5
103 aa
hypothetical protein
0.033
○○○○○ 2.33
2.3262539165313
Escherichia coli O157:H7 str. EDL933
Z1939
AAG56028.1
122 aa
orf, hypothetical protein
0.012
○○○○○ 2.33
2.32769900864742
Mycobacterium avium subsp. paratuberculosis K10
MAP_3931
AAS06481.1
Q73SZ1
412 aa
hypothetical protein
0.0087
○○○○○ 2.33
2.32771543979003
Mycobacterium avium subsp. paratuberculosis K10
MAP_3773c
AAS06323.1
Q73TE5
139 aa
hypothetical protein
0.0087
○○○○○ 2.33
2.32831000672177
Mycobacterium avium subsp. paratuberculosis K10
MAP_3249
AAS05797.1
Q73UW7
546 aa
hypothetical protein
0.0087
○○○○○ 2.33
2.32850279921807
Mycobacterium avium subsp. paratuberculosis K10
MAP_2969c
AAS05286.1
Q73VP4
101 aa
hypothetical protein
0.0086
○○○○○ 2.33
2.33122285637793
Streptococcus pyogenes M1 5448
SP5448_03535
WP_011285628.1
61 aa
hypothetical protein
0.045
○○○○○ 2.33
2.33490979548038
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0183
WP_002778629.1
A0A0H3PAP0
trx
104 aa
thioredoxin
0.014
○○○○○ 2.34
2.33628092606
Mycobacterium avium subsp. paratuberculosis K10
MAP_2308c
AAS04625.1
Q73XK1
pdhB
351 aa
PdhB
0.0085
○○○○○ 2.34
2.33699932602974
Mycobacterium avium subsp. paratuberculosis K10
MAP_4285
AAS06835.1
Q73RZ3
500 aa
hypothetical protein
0.0085
○○○○○ 2.34
2.33727159395705
Mycobacterium avium subsp. paratuberculosis K10
MAP_1592
AAS03909.1
Q73ZL0
147 aa
hypothetical protein
0.0085
○○○○○ 2.34
2.33777424973526
Streptococcus pyogenes M1 5448
SP5448_05275
WP_002984663.1
196 aa
threonylcarbamoyl-AMP synthase
0.019
○○○○○ 2.34
2.33779380497457
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