Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Streptococcus pyogenes M1 5448  SP5448_04020  WP_011285597.1  361 aa DEAD/DEAH box helicase n.s. ●○○○○ -0.51 -0.514107050184467
Streptococcus pyogenes M1 5448  SP5448_05225  WP_002984641.1  249 aa sortase n.s. ●○○○○ -0.51 -0.513914782884854
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0212  WP_011812694.1  A0A0H3PJ89  38 aa hypothetical protein n.s. ●○○○○ -0.51 -0.513827099955
Serratia marcescens Strain UMH9  BVG96_01860  ASL96428.1  627 aa peptidylprolyl isomerase n.s. ●○○○○ -0.51 -0.51380439535379
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1051  WP_002855808.1  A0A0H3P9D1  246 aa multidrug efflux RND transporter periplasmic adaptor subunit CmeE n.s. ●○○○○ -0.51 -0.513430255818
Escherichia coli CFT073  c3724  AAN82168.1  A0A0H2VAV4  pitB  499 aa Probable low-affinity inorganic phosphate transporter 2 n.s. ●○○○○ -0.51 -0.513367639001964
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2746  CBW18846.1  A0A0H3NQJ0  427 aa hypothetical inner membrane protein n.s. ●○○○○ -0.51 -0.513029884413691
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1599  CBW17694.1  A0A0H3NLL6  660 aa invasin-like protein n.s. ●○○○○ -0.51 -0.512945294735855
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3616  CBW19709.1  A0A0H3NHB3  138 aa conserved hypothetical protein n.s. ●○○○○ -0.51 -0.512717821758412
Streptococcus pyogenes M1 5448  SP5448_06945  WP_010922040.1  399 aa glycoside hydrolase family 88 protein n.s. ●○○○○ -0.51 -0.51266504543737
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4412  CBW20500.1  A0A0H3NL46  idnT  406 aa gnt-ii system l-idonate transporter (l-ido transporter) n.s. ●○○○○ -0.51 -0.512504687389222
Escherichia coli CFT073  c4099  AAN82537.1  A0A0H2VBQ1  hofG  145 aa Putative general secretion pathway protein G precursor n.s. ●○○○○ -0.51 -0.512504443070141
Haemophilus influenzae Rd KW20  HI_0413  NP_438575.2  P44443  rne  935 aa ribonuclease E n.s. ●○○○○ -0.51 -0.512410402314113
Streptococcus pyogenes M1 5448  SP5448_07230  WP_010922009.1  274 aa asparagine ligase A n.s. ●○○○○ -0.51 -0.512376644487951
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1130  WP_002853613.1  A0A0H3PCT3  msrB  119 aa methionine-R-sulfoxide reductase n.s. ●○○○○ -0.51 -0.512282620952
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2327  CBW18429.1  A0A0H3NJS7  367 aa conserved hypothetical protein n.s. ●○○○○ -0.51 -0.512233256615127
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3799  CBW19890.1  A0A0H3NHN5  420 aa hypothetical membrane transport protein n.s. ●○○○○ -0.51 -0.512091544466583
Mycobacterium avium subsp. paratuberculosis K10  MAP_4008  AAS06558.1  Q73SR5  437 aa hypothetical protein n.s. ●○○○○ -0.51 -0.511710903762903
Mycobacterium avium subsp. paratuberculosis K10  MAP_2830c  AAS05147.1  Q73W30  278 aa hypothetical protein n.s. ●○○○○ -0.51 -0.511693071852727
Serratia marcescens Strain UMH9  BVG96_20290  ASL99818.1  179 aa GTPase-activating protein n.s. ●○○○○ -0.51 -0.511618524599453
Mycobacterium avium subsp. paratuberculosis K10  MAP_0780  AAS03097.1  Q742Q5  fadD3  478 aa FadD3_2 n.s. ●○○○○ -0.51 -0.511564466242576
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4128  AIK82674.1  359 aa fructose-bisphosphate aldolase, class II n.s. ●○○○○ -0.51 -0.511479090989234
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2469  AIK81066.1  901 aa preprotein translocase, SecA subunit n.s. ●○○○○ -0.51 -0.511479087326928
Escherichia coli M12  CO715_12160  ATI06396.1  201 aa type II secretion system protein GspJ n.s. ●○○○○ -0.51 -0.511300869695243
Escherichia coli CFT073  c2671  AAN81127.1  Q8FFV6  mdtQ  508 aa Putative channel/filament proteins n.s. ●○○○○ -0.51 -0.511014144189829
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1628  CBW17723.1  A0A0H3NH61  steC  457 aa Type III secretion system effector protein, has Kinase activity and aids formation of F-actin meshwork n.s. ●○○○○ -0.51 -0.51081964056837
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2691  CBW18793.1  A0A0H3NKU3  360 aa hypothetical major capsid protein n.s. ●○○○○ -0.51 -0.510737779711895
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4161  CBW20249.1  A0A0H3NVD3  yjbH  698 aa hypothetical lipoprotein n.s. ●○○○○ -0.51 -0.510726638943362
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1585  WP_002855985.1  A0A0H3PIL4  hisD  428 aa histidinol dehydrogenase n.s. ●○○○○ -0.51 -0.510600805097
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1070  CBW17166.1  A0A0H3NA50  426 aa hypothetical transporter n.s. ●○○○○ -0.51 -0.510538442556357
Serratia marcescens Strain UMH9  BVG96_19825  ASL99730.1  257 aa acetylglutamate kinase n.s. ●○○○○ -0.51 -0.510412272121602
Serratia marcescens Strain UMH9  BVG96_09060  ASL97755.1  458 aa cation transporter n.s. ●○○○○ -0.51 -0.510242035095277
Escherichia coli CFT073  c5378  AAN83800.1  A0A0H2VDP7  1092 aa Hypothetical protein n.s. ●○○○○ -0.51 -0.510214227106601
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1195  WP_002852807.1  A0A0H3P9C0  211 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.51 -0.510167600359
Serratia marcescens Strain UMH9  BVG96_08065  ASL97575.1  352 aa 2,5-dihydroxypyridine 5,6-dioxygenase n.s. ●○○○○ -0.51 -0.509935311044785
Vibrio parahaemolyticus RIMD 2210633  VPA_0448  BAC61791.1  Q87J07  244 aa hypothetical protein n.s. ●○○○○ -0.51 -0.509877858374548
Serratia marcescens Strain UMH9  BVG96_00255  ASL96135.1  234 aa thiamine ABC transporter ATP-binding protein n.s. ●○○○○ -0.51 -0.50975238131816
Vibrio parahaemolyticus RIMD 2210633  VP_2073  BAC60336.1  Q87N03  dsbB  178 aa disulfide bond formation protein B n.s. ●○○○○ -0.51 -0.50974991756845
Escherichia coli CFT073  c3483  AAN81931.1  Q8FE67  gcvP  957 aa Glycine dehydrogenase (decarboxylating) n.s. ●○○○○ -0.51 -0.509614642695861
Acinetobacter baumannii ATCC 17978  A1S_1764  ABO12191.2  102 aa putative transcriptional regulator n.s. ●○○○○ -0.51 -0.509556754532831
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0249  WP_002869256.1  A1VXU6  argC  342 aa N-acetyl-gamma-glutamyl-phosphate reductase n.s. ●○○○○ -0.51 -0.509506805717
Serratia marcescens Strain UMH9  BVG96_13900  ASL98657.1  150 aa Na(+)-translocating NADH-quinone reductase subunit E n.s. ●○○○○ -0.51 -0.50901544570934
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4475  AIK83018.1  119 aa glucitol operon activator family protein n.s. ●○○○○ -0.51 -0.509001300885904
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0625  CBW16725.1  A0A0H3N8V7  dacA  403 aa D-alanine carboxypeptidase n.s. ●○○○○ -0.51 -0.508990043267142
Escherichia coli O157:H7 str. EDL933  Z0392  AAG54648.1  158 aa hypothetical protein n.s. ●○○○○ -0.51 -0.508814170272869
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4235  CBW20321.1  A0A0H3NIK7  melA  451 aa alpha-galactosidase n.s. ●○○○○ -0.51 -0.508784618243263
Serratia marcescens Strain UMH9  BVG96_18015  ASL99402.1  325 aa oxidoreductase n.s. ●○○○○ -0.51 -0.508765510655816
Vibrio parahaemolyticus RIMD 2210633  VP_0110  BAC58373.1  Q87TF9  205 aa cytochrome c4 n.s. ●○○○○ -0.51 -0.508477350425898
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1163  WP_002869015.1  A0A0H3PH28  waaV  275 aa glycosyltransferase family 2 protein n.s. ●○○○○ -0.51 -0.508222819118
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1864  CBW17958.1  A0A0H3NCF6  araH  185 aa conserved hypothetical protein n.s. ●○○○○ -0.51 -0.508198241996291
Vibrio parahaemolyticus RIMD 2210633  VP_1778  BAC60041.1  Q87NU0  185 aa putative transcriptional regulator n.s. ●○○○○ -0.51 -0.508147979216179
Streptococcus pyogenes M1 5448  SP5448_06185  WP_011285486.1  72 aa hypothetical protein n.s. ●○○○○ -0.51 -0.508146763896465
Mycobacterium avium subsp. paratuberculosis K10  MAP_2571c  AAS04888.1  Q73WT9  fadD6  592 aa FadD6 n.s. ●○○○○ -0.51 -0.508042074164748
Streptococcus pyogenes M1 5448  SP5448_01990  WP_027968785.1  82 aa pyruvate kinase n.s. ●○○○○ -0.51 -0.507954496596852
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3111  CBW19210.1  A0A0H3NFY4  uxaC  470 aa Uronate isomerase n.s. ●○○○○ -0.51 -0.507949432490702
Escherichia coli CFT073  c3415  AAN81860.1  Q8CVS2  ptrA  962 aa Protease III precursor n.s. ●○○○○ -0.51 -0.507697403599858
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3525  AIK82082.1  178 aa mannitol operon repressor n.s. ●○○○○ -0.51 -0.507400967157234
Vibrio parahaemolyticus RIMD 2210633  VP_1632  BAC59895.1  Q87P86  214 aa putative outer membrane protein n.s. ●○○○○ -0.51 -0.507172573282633
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0849  WP_002868807.1  A0A0H3PAQ1  577 aa Na+/H+ antiporter NhaC family protein n.s. ●○○○○ -0.51 -0.50705422434
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3123  CBW19222.1  A0A0H3NFZ4  hybA  328 aa hydrogenase-2 small subunit n.s. ●○○○○ -0.51 -0.506933345930579
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3537  WP_001241377.1  E8XD80  yhdA  646 aa RNase E specificity factor CsrD n.s. ●○○○○ -0.51 -0.506921804909418
Streptococcus pyogenes M1 5448  SP5448_01675  WP_010922641.1  431 aa MFS transporter n.s. ●○○○○ -0.51 -0.506897026448981
Streptococcus pyogenes M1 5448  SP5448_01675  WP_011285137.1  48 aa universal stress protein n.s. ●○○○○ -0.51 -0.506897026448981
Streptococcus pyogenes M1 5448  SP5448_07100  WP_002990568.1  308 aa U32 family peptidase n.s. ●○○○○ -0.51 -0.506897026448981
Serratia marcescens Strain UMH9  BVG96_10630  ASL98046.1  280 aa PTS mannose transporter subunit IID n.s. ●○○○○ -0.51 -0.506685927276097
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2883  CBW18981.1  A0A0H3NR20  35 aa salmonella pathogenicity island 1 protein n.s. ●○○○○ -0.51 -0.506613465818433
Streptococcus pyogenes M1 5448  SP5448_07245  WP_010922006.1  150 aa phage portal protein n.s. ●○○○○ -0.51 -0.506608625499562
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1431  CBW17526.1  A0A0H3NL78  ynfC  239 aa conserved hypothetical protein n.s. ●○○○○ -0.51 -0.506315570216388
Mycobacterium avium subsp. paratuberculosis K10  MAP_4306  AAS06856.1  Q73RX2  390 aa hypothetical protein n.s. ●○○○○ -0.51 -0.50620907583651
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1394  WP_001060729.1  E8XH83  319 aa DUF523 and DUF1722 domain-containing protein n.s. ●○○○○ -0.51 -0.506130981544518
Serratia marcescens Strain UMH9  BVG96_22005  ASM00119.1  68 aa MbtH family protein n.s. ●○○○○ -0.51 -0.506009202230645
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0466  WP_072225850.1  A0A0H3PAD1  222 aa thiaminase II n.s. ●○○○○ -0.51 -0.505684741125
Vibrio parahaemolyticus RIMD 2210633  VPA_1422  BAC62765.1  Q87G95  258 aa putative PTS system, nitrogen regulatory IIA component n.s. ●○○○○ -0.51 -0.505680945276669
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0428  CBW16528.1  A0A0H3N8X4  apbA  303 aa 2-dehydropantoate 2-reductase n.s. ●○○○○ -0.51 -0.505448507889245
Mycobacterium avium subsp. paratuberculosis K10  MAP_4265  AAS06815.1  P60545  groL1  538 aa GroEL1 n.s. ●○○○○ -0.51 -0.505166612523641
Porphyromonas gingivalis ATCC 33277  PGN_1226  WP_012458120.1  B2RK50  850 aa adenosylcobalamin-dependent ribonucleoside-diphosphate reductase n.s. ●○○○○ -0.51 -0.505146153317728
Serratia marcescens Strain UMH9  BVG96_06230  ASL97237.1  395 aa MexE family multidrug efflux RND transporter periplasmic adaptor subunit n.s. ●○○○○ -0.51 -0.505086545778947
Escherichia coli O157:H7 str. EDL933  Z2163  AAG56227.1  296 aa orf, hypothetical protein n.s. ●○○○○ -0.5 -0.504963617171271
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0035  WP_002873268.1  Q1HG72  gltD  481 aa glutamate synthase subunit beta n.s. ●○○○○ -0.5 -0.504938208518
Serratia marcescens Strain UMH9  BVG96_22925  ASM00287.1  363 aa HNH endonuclease n.s. ●○○○○ -0.5 -0.504885951435796
Escherichia coli O157:H7 str. EDL933  Z1006  AAG55158.1  237 aa orf, hypothetical protein n.s. ●○○○○ -0.5 -0.5047360094483
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0123  WP_002857725.1  A0A0H3PA60  dcuA  445 aa anaerobic C4-dicarboxylate transporter n.s. ●○○○○ -0.5 -0.504495018971
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2555  CBW18656.1  A0A0H3NKK5  245 aa predicted bacteriophage protein n.s. ●○○○○ -0.5 -0.503999301166484
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1790  WP_001257065.1  E8X8D9  ychA  269 aa tetratricopeptide repeat-containing protein n.s. ●○○○○ -0.5 -0.50399324845544
Serratia marcescens Strain UMH9  BVG96_00275  ASM00436.1  57 aa hypothetical protein n.s. ●○○○○ -0.5 -0.503973141563314
Serratia marcescens Strain UMH9  BVG96_17660  ASL99336.1  310 aa TIGR01212 family radical SAM protein n.s. ●○○○○ -0.5 -0.503654253303792
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1411  WP_002869134.1  A0A0H3PBI9  373 aa membrane protein n.s. ●○○○○ -0.5 -0.50358747587
Mycobacterium avium subsp. paratuberculosis K10  MAP_2172c  AAS04489.1  Q73XY6  421 aa hypothetical protein n.s. ●○○○○ -0.5 -0.503541726404834
Vibrio parahaemolyticus RIMD 2210633  VPA_0687  BAC62030.1  Q87IB9  192 aa hypothetical protein n.s. ●○○○○ -0.5 -0.503467465878425
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2143  CBW18239.1  A0A0H3ND92  yehZ  305 aa hypothetical periplasmic protein n.s. ●○○○○ -0.5 -0.503457382503248
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3944  CBW20035.1  A0A0H3NI10  rodA  328 aa serine/threonine protein kinase n.s. ●○○○○ -0.5 -0.503292784764388
Serratia marcescens Strain UMH9  BVG96_10795  ASL98077.1  335 aa cytochrome d ubiquinol oxidase subunit II n.s. ●○○○○ -0.5 -0.50291625566408
Escherichia coli CFT073  c2658  AAN81114.1  A0A0H2V8S1  yehW  243 aa Hypothetical ABC transporter permease protein yehW n.s. ●○○○○ -0.5 -0.502561415518887
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2611  CBW18713.1  A0A0H3NKN4  ung  229 aa Uracil-DNA glycosylase n.s. ●○○○○ -0.5 -0.502466952602047
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3950  CBW20040.1  A0A0H3NI13  yihI  171 aa conserved hypothetical protein n.s. ●○○○○ -0.5 -0.502410754503323
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0711  WP_000811134.1  E8XA42  citB  379 aa tricarballylate utilization protein TcuB n.s. ●○○○○ -0.5 -0.502382934514333
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4775  WP_000224870.1  E8XDA3  deoD  239 aa purine-nucleoside phosphorylase n.s. ●○○○○ -0.5 -0.502094556452403
Serratia marcescens Strain UMH9  BVG96_18840  ASL99554.1  191 aa glutamine amidotransferase n.s. ●○○○○ -0.5 -0.50208409873258
Vibrio parahaemolyticus RIMD 2210633  VP_2431  BAC60694.1  Q87M27  326 aa phosphoserine phosphatase n.s. ●○○○○ -0.5 -0.502070815481219
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0875  WP_002860516.1  A0A0H3PAW3  142 aa hypothetical protein n.s. ●○○○○ -0.5 -0.50202411986
Retrieved entries 12,701–12,800 out of 36,363 total in 143.6 ms (Link to these results)