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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_15385  ATI06974.1  224 aa MOSC domain-containing protein 5.0e-5 ●○○○○ -0.51 -0.509005763538505
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4456  AIK82999.1  569 aa hydrogenase 4, large subunit <1e-323 ●○○○○ -0.51 -0.508331035678011
Escherichia coli M12  CO715_11915  ATI06351.1  164 aa TIGR00645 family protein 3.0e-16 ●○○○○ -0.51 -0.507962533467261
Escherichia coli M12  CO715_00420  ATI04331.1  466 aa MFS transporter 4.4e-95 ●○○○○ -0.51 -0.507336595424514
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2662  WP_001187150.1  E8XGP9  cadC  514 aa CadC family transcriptional regulator 0.027 ●○○○○ -0.51 -0.507216706083576
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0618  NP_233007.1  Q9KLX3  254 aa molybdopterin biosynthesis protein MoeB 0.00016 ●○○○○ -0.51 -0.506931499967065
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3452  AIK82008.1  519 aa PTS system, glucose-like IIB component domain protein <1e-323 ●○○○○ -0.51 -0.506902311815675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0102  NP_232503.1  Q9KN63  219 aa CbbY family protein 1.3e-5 ●○○○○ -0.51 -0.506796224815726
Escherichia coli M12  CO715_07135  ATI05510.1  380 aa integrase 1.6e-12 ●○○○○ -0.51 -0.505041489267777
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4711  AIK83246.1  664 aa transketolase <1e-323 ●○○○○ -0.5 -0.504528077514068
Escherichia coli M12  CO715_09970  ATI06008.1  746 aa TonB-dependent siderophore receptor 3.3e-6 ●○○○○ -0.5 -0.503789613182284
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4648  AIK83182.1  280 aa hypothetical protein <1e-323 ●○○○○ -0.5 -0.50377285911206
Porphyromonas gingivalis ATCC 33277  PGN_0090  WP_012457233.1  B2RGW4  117 aa DNA-binding protein <1e-323 ●○○○○ -0.5 -0.503752200777811
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4386  AIK82929.1  916 aa hybrid sensory histidine kinase, in two-component regulatory system with UvrY <1e-323 ●○○○○ -0.5 -0.50351482077411
Escherichia coli M12  CO715_21710  ATI08113.1  1265 aa molybdate metabolism regulator 7.5e-6 ●○○○○ -0.5 -0.503372321153786
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1009  NP_230655.1  Q9KT94  146 aa hypothetical protein 0.00048 ●○○○○ -0.5 -0.502988395479895
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4343  AIK82888.1  181 aa cobU 7.6e-6 ●○○○○ -0.5 -0.502932242896057
Escherichia coli M12  CO715_12965  ATI06538.1  92 aa transcriptional regulator 1.1e-6 ●○○○○ -0.5 -0.50253773709679
Acinetobacter baumannii ATCC 17978  A1S_2143  ABO12570.2  150 aa putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.02 ●○○○○ -0.5 -0.502511592946608
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0028  NP_229687.1  Q9KVW0  ilvD  613 aa dihydroxy-acid dehydratase 1.3e-5 ●○○○○ -0.5 -0.502436600392647
Porphyromonas gingivalis ATCC 33277  PGN_1505  WP_080504424.1  B2RKX9  429 aa bifunctional folylpolyglutamate synthase/dihydrofolate synthase 9.7e-8 ●○○○○ -0.5 -0.502356237606722
Escherichia coli M12  CO715_16500  ATI07174.1  443 aa MFS transporter 8.4e-10 ●○○○○ -0.5 -0.502329091082542
Porphyromonas gingivalis ATCC 33277  PGN_0289  WP_012457397.1  B2RHG3  mfa3  446 aa hypothetical protein <1e-323 ●○○○○ -0.5 -0.501894991845105
Escherichia coli M12  CO715_22045  ATI08177.1  426 aa colanic acid biosynthesis pyruvyl transferase WcaK 5.1e-20 ●○○○○ -0.5 -0.501703153039795
Porphyromonas gingivalis ATCC 33277  PGN_0534  WP_004584080.1  B2RI58  280 aa carboxylating nicotinate-nucleotide diphosphorylase <1e-323 ●○○○○ -0.5 -0.501555700252329
Porphyromonas gingivalis ATCC 33277  PGN_1197  WP_012458096.1  B2RK21  283 aa ATPase 1.2e-10 ●○○○○ -0.5 -0.501433526154642
Escherichia coli M12  CO715_02180  ATI04644.1  135 aa PTS sorbose transporter subunit IIA 1.7e-7 ●○○○○ -0.5 -0.499825338911555
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1008  NP_233392.1  Q9KKU2  331 aa outer membrane protein 0.0021 ●○○○○ -0.5 -0.499743134310793
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3352  AIK81909.1  188 aa chromate reductase monomer <1e-323 ●○○○○ -0.5 -0.499454750372802
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4480  WP_011233236.1  E8X9T5  yjcO  715 aa formate dehydrogenase H subunit alpha, selenocysteine-containing 0.012 ●○○○○ -0.5 -0.499399915967471
Escherichia coli M12  CO715_21880  ATI08146.1  471 aa MFS transporter 2.4e-9 ●○○○○ -0.5 -0.49899075485456
Escherichia coli M12  CO715_10250  ATI06046.1  823 aa exonuclease 6.4e-8 ●○○○○ -0.5 -0.49899075485456
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2387  WP_000427827.1  E8XED3  yfaW  405 aa L-rhamnonate dehydratase 0.02 ●○○○○ -0.5 -0.498674678936123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2927  AIK81513.1  856 aa type VII secretion system (T7SS), usher family protein 2.9e-13 ●○○○○ -0.5 -0.498586444419418
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0089  NP_229748.1  Q9KVQ2  333 aa cytochrome c551 peroxidase 1.3e-5 ●○○○○ -0.5 -0.498343874773222
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0256  NP_232654.1  Q9KMR4  223 aa transcriptional regulator 3.6e-5 ●○○○○ -0.5 -0.498160914784498
Escherichia coli M12  CO715_21220  ATI08024.1  149 aa periplasmic nitrate reductase electron transfer subunit 5.3e-19 ●○○○○ -0.5 -0.498156170797564
Escherichia coli M12  CO715_18065  ATI07454.1  298 aa LysR family transcriptional regulator 4.5e-9 ●○○○○ -0.5 -0.497947524783315
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0771  NP_230420.1  P0C6D3  vibB  293 aa vibriobactin-specific isochorismatase 7.6e-7 ●○○○○ -0.5 -0.497840286554261
Escherichia coli M12  CO715_17745  ATI07399.1  315 aa YscQ/HrcQ family type III secretion apparatus protein 5.0e-209 ●○○○○ -0.5 -0.497530232754818
Escherichia coli M12  CO715_10000  ATI06011.1  232 aa phage minor tail protein L 0.015 ●○○○○ -0.5 -0.49711294072632
Escherichia coli M12  CO715_08790  ATI05802.1  760 aa TonB-dependent siderophore receptor 1.7e-17 ●○○○○ -0.5 -0.496904294712071
Acinetobacter baumannii ATCC 17978  A1S_1424  ABO11852.2  283 aa malonate decarboxylase beta subunit 0.01 ●○○○○ -0.5 -0.496265851533554
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4404  AIK82947.1  201 aa adenylylsulfate kinase 2.2e-16 ●○○○○ -0.5 -0.496210823913605
Porphyromonas gingivalis ATCC 33277  PGN_1692  WP_005875396.1  B2RLG6  74 aa DUF3343 domain-containing protein <1e-323 ●○○○○ -0.5 -0.495837744172199
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3583  AIK82138.1  517 aa cellulose biosynthesis protein BcsE 1.6e-7 ●○○○○ -0.5 -0.495079571485446
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2949  AIK81534.1  671 aa poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 1.1e-8 ●○○○○ -0.49 -0.494553214921837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2780  AIK81369.1  622 aa pfkB carbohydrate kinase family protein <1e-323 ●○○○○ -0.49 -0.494205000938142
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3824  AIK82374.1  481 aa modulator of DNA gyrase family protein <1e-323 ●○○○○ -0.49 -0.494187176347172
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2886  AIK81475.1  141 aa nsrR 1.0e-12 ●○○○○ -0.49 -0.493950775822928
Escherichia coli M12  CO715_14750  ATI06861.1  369 aa branched chain amino acid ABC transporter substrate-binding protein 1.0e-20 ●○○○○ -0.49 -0.493774604498338
Escherichia coli M12  CO715_02705  ATI04742.1  479 aa hydrogenase-4 component D 4.2e-18 ●○○○○ -0.49 -0.492522728412845
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4149  AIK82695.1  203 aa DSBA-like thioredoxin domain protein 5.7e-15 ●○○○○ -0.49 -0.492501726694177
Porphyromonas gingivalis ATCC 33277  PGN_0873  WP_012457842.1  B2RJ47  236 aa DUF3256 family protein 0.0078 ●○○○○ -0.49 -0.492006918722295
Escherichia coli M12  CO715_01695  ATI04556.1  500 aa proline/betaine transporter 5.1e-6 ●○○○○ -0.49 -0.491896790370098
Acinetobacter baumannii ATCC 17978  A1S_2530  ABO12947.2  215 aa 4-amino-4-deoxychorismate lyase 0.0022 ●○○○○ -0.49 -0.491628738379464
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4218  AIK82763.1  517 aa H+ symporter family protein 5.8e-14 ●○○○○ -0.49 -0.491404734946161
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3468  AIK82024.1  693 aa ATP-dependent DNA helicase RecG 5.5e-15 ●○○○○ -0.49 -0.491382215309642
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3627  AIK82182.1  551 aa 4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase <1e-323 ●○○○○ -0.49 -0.491049673586487
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0112  NP_229771.1  Q9KVM9  223 aa cytochrome c4 8.0e-7 ●○○○○ -0.49 -0.490962555070662
Acinetobacter baumannii ATCC 17978  A1S_2090  ABO12517.2  234 aa hypothetical protein 0.0085 ●○○○○ -0.49 -0.490937972421522
Escherichia coli M12  CO715_08565  ATI05762.1  410 aa multidrug transporter MdfA 1.2e-19 ●○○○○ -0.49 -0.490227622256107
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3905  WP_000818607.1  E8XGT1  slmA  198 aa nucleoid occlusion factor SlmA 0.014 ●○○○○ -0.49 -0.489565914284435
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0024  WP_001245854.1  E8XG44  bcfC  873 aa fimbrial biogenesis outer membrane usher protein 0.048 ●○○○○ -0.49 -0.489391680559862
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0467  NP_232859.1  Q9KMA7  52 aa hypothetical protein 0.00016 ●○○○○ -0.49 -0.488942178185822
Acinetobacter baumannii ATCC 17978  A1S_2511  ABO12929.2  145 aa Phenylacetic acid degradation-related protein 0.045 ●○○○○ -0.49 -0.487999701327703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2227  AIK80832.1  269 aa pyrroline-5-carboxylate reductase 3.7e-6 ●○○○○ -0.49 -0.48772292507304
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0554  NP_232944.1  Q9KM35  410 aa oxalate/formate antiporter 4.9e-5 ●○○○○ -0.49 -0.487687800479674
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0099  NP_232500.1  Q9KN66  346 aa Gfo/Idh/MocA family oxidoreductase 9.3e-5 ●○○○○ -0.49 -0.487669636925132
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1607  NP_231247.1  Q9KRM9  324 aa hypothetical protein 2.5e-7 ●○○○○ -0.49 -0.487608800378793
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2638  NP_232266.1  Q9KNU2  484 aa dihydrolipoamide dehydrogenase 0.00016 ●○○○○ -0.49 -0.487598724052918
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1822  WP_000338376.1  E8X8H1  ycgO  577 aa potassium/proton antiporter 0.012 ●○○○○ -0.49 -0.487528502413432
Porphyromonas gingivalis ATCC 33277  PGN_0132  WP_004584708.1  B2RH06  158 aa hypothetical protein 1.1e-5 ●○○○○ -0.49 -0.487382935211098
Acinetobacter baumannii ATCC 17978  A1S_2047  ABO12474.2  342 aa putative lysophospholipase 0.013 ●○○○○ -0.49 -0.487232968596633
Escherichia coli M12  CO715_21090  ATI08002.1  413 aa MFS transporter 7.3e-11 ●○○○○ -0.49 -0.486889286028126
Escherichia coli M12  CO715_13540  ATI06638.1  187 aa hypothetical protein 0.00052 ●○○○○ -0.49 -0.486680640013877
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2825  AIK81414.1  372 aa cys/Met metabolism PLP-dependent enzyme family protein <1e-323 ●○○○○ -0.49 -0.485986840579237
Escherichia coli M12  CO715_00815  ATI04403.1  142 aa heat-shock protein IbpB 0.0057 ●○○○○ -0.49 -0.485428763928384
Escherichia coli M12  CO715_12295  ATI06417.1  201 aa L(+)-tartrate dehydratase subunit beta 4.2e-47 ●○○○○ -0.49 -0.485220117914135
Escherichia coli M12  CO715_20505  ATI07895.1  418 aa hypothetical protein 1.1e-104 ●○○○○ -0.48 -0.484176887842891
Escherichia coli M12  CO715_13070  ATI06557.1  217 aa glutamine amidotransferase 0.025 ●○○○○ -0.48 -0.483759595814393
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4271  AIK82815.1  237 aa putative aspartate/glutamate racemase 5.6e-16 ●○○○○ -0.48 -0.483147367786938
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3717  AIK82272.1  108 aa nitrite reductase [NAD(P)H] small subunit 7.2e-7 ●○○○○ -0.48 -0.482817411821624
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4942  AIK83468.1  303 aa tRNA dihydrouridine synthase 0.00018 ●○○○○ -0.48 -0.482813081392585
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0471  NP_232863.1  H9L4R6  51 aa hypothetical protein 0.0069 ●○○○○ -0.48 -0.482405559853769
Escherichia coli M12  CO715_10595  ATI06107.1  424 aa tyrosine--tRNA ligase 0.0025 ●○○○○ -0.48 -0.481881781686153
Porphyromonas gingivalis ATCC 33277  PGN_1245  WP_012458135.1  B2RK69  608 aa long-chain fatty acid--CoA ligase 1.1e-9 ●○○○○ -0.48 -0.481261608658052
Escherichia coli M12  CO715_01900  ATI04592.1  104 aa hypothetical protein 6.4e-15 ●○○○○ -0.48 -0.481255843643407
Porphyromonas gingivalis ATCC 33277  PGN_1268  WP_039417529.1  B2RK92  246 aa (Fe-S)-binding protein <1e-323 ●○○○○ -0.48 -0.479749504483764
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3010  AIK81595.1  285 aa binding-protein-dependent transport system innermembrane component family protein <1e-323 ●○○○○ -0.48 -0.47963102483037
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1603  AIK80223.1  377 aa potG 2.6e-14 ●○○○○ -0.48 -0.479611394771636
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1268  AIK79891.1  427 aa hypothetical protein 3.3e-16 ●○○○○ -0.48 -0.479362639013665
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3478  AIK82034.1  287 aa hypothetical protein 0.0038 ●○○○○ -0.48 -0.479325526577835
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1612  NP_231252.1  Q9KRM4  237 aa fimbrial biogenesis and twitching motility protein 1.6e-7 ●○○○○ -0.48 -0.479137062205483
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3715  AIK82270.1  334 aa tryptophan--tRNA ligase 2.7e-5 ●○○○○ -0.48 -0.478491563799681
Escherichia coli M12  CO715_05220  ATI05181.1  221 aa YecA family protein 4.1e-14 ●○○○○ -0.48 -0.477917507415425
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1740  WP_001194372.1  E8XKU0  trpE  520 aa anthranilate synthase component I 0.015 ●○○○○ -0.48 -0.477727203017096
Escherichia coli M12  CO715_07300  ATI05538.1  70 aa cold-shock protein CspG 7.8e-11 ●○○○○ -0.48 -0.477708861401176
Porphyromonas gingivalis ATCC 33277  PGN_1975  WP_004583671.1  B2RM98  169 aa Cys-tRNA(Pro) deacylase 5.7e-15 ●○○○○ -0.48 -0.477692583189274
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0539  NP_230190.1  Q9KUI2  283 aa sulfate ABC transporter permease 0.0069 ●○○○○ -0.48 -0.477546058757699
Retrieved entries 5,501–5,600 out of 36,363 total in 4.4 ms (Link to these results)