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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2609  WP_001738968.1  E8XGJ7  109 aa DUF1493 family protein 4.3e-5 ●●●○○ -2.13 -2.12780217360456
Acinetobacter baumannii ATCC 17978  A1S_0623  ABO11072.2  704 aa DNA mismatch repair enzyme 2.5e-12 ●●●○○ -2.13 -2.12731037581353
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3483  WP_000243749.1  E8XD26  rapZ  284 aa RNase adapter RapZ 3.2e-5 ●●●○○ -2.13 -2.12657529568874
Mycobacterium avium subsp. paratuberculosis K10  MAP_2009  AAS04326.1  Q73YE7  207 aa hypothetical protein 0.014 ●●●○○ -2.12 -2.12487488823673
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3666  CBW19759.1  A0A0H3NHE5  gpsA  339 aa glycerol-3-phosphate dehydrogenase 0.0028 ●●●○○ -2.12 -2.1227031946685
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4635  WP_001232231.1  E8XBJ1  cybC  128 aa cytochrome b562 6.5e-16 ●●●○○ -2.12 -2.12246320124843
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2728  AIK81318.1  740 aa glycosyl transferases group 1 family protein <1e-323 ●●●○○ -2.12 -2.12191567445051
Acinetobacter baumannii ATCC 17978  A1S_3455  ABO13844.2  A3MAA0  ilvD  609 aa dihydroxy-acid dehydratase 4.6e-33 ●●●○○ -2.12 -2.12093849617274
Escherichia coli O157:H7 str. EDL933  Z0275  AAG54543.1  390 aa hypothetical protein 0.019 ●●●○○ -2.12 -2.11845421958168
Acinetobacter baumannii ATCC 17978  A1S_3187  ABO13582.2  A3M9I8  aroB  360 aa 3-dehydroquinate synthase 4.9e-6 ●●●○○ -2.12 -2.11839457050185
Acinetobacter baumannii ATCC 17978  A1S_0778  ABO11218.2  687 aa methionyl-tRNA synthetase 3.9e-30 ●●●○○ -2.12 -2.11795209789724
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4100  AIK82646.1  243 aa ribosomal RNA small subunit methyltransferase E 4.2e-10 ●●●○○ -2.12 -2.11777877219051
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1970  WP_000781520.1  E8XA84  yeca  221 aa YecA family protein 0.00011 ●●●○○ -2.12 -2.11649918013445
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0205  WP_000951687.1  E8XHZ4  stfC  885 aa fimbrial biogenesis outer membrane usher protein 2.5e-5 ●●●○○ -2.11 -2.11480774248261
Mycobacterium avium subsp. paratuberculosis K10  MAP_0758  AAS03075.1  Q742S7  281 aa hypothetical protein 0.014 ●●●○○ -2.11 -2.11431658922877
Escherichia coli M12  CO715_22125  ATI08189.1  616 aa dihydroxy-acid dehydratase 4.6e-17 ●●●○○ -2.11 -2.11224173702675
Mycobacterium avium subsp. paratuberculosis K10  MAP_1848c  AAS04165.1  Q73YV7  222 aa hypothetical protein 0.014 ●●●○○ -2.11 -2.11185916934537
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3585  AIK82140.1  171 aa yhjQ family protein <1e-323 ●●●○○ -2.11 -2.11162042111305
Vibrio parahaemolyticus RIMD 2210633  VP_0178  BAC58441.1  Q87T92  pyrE  213 aa orotate phosphoribosyltransferase 0.038 ●●●○○ -2.11 -2.109171551192
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0327  WP_001225658.1  E8XJL5  yafK  246 aa murein L,D-transpeptidase 9.7e-16 ●●●○○ -2.11 -2.10831251381977
Acinetobacter baumannii ATCC 17978  A1S_0415  ABO10870.2  216 aa putative hydrolase haloacid dehalogenase-like family 5.2e-21 ●●●○○ -2.11 -2.10810480903333
Acinetobacter baumannii ATCC 17978  A1S_2900  ABO13306.2  255 aa putative lipopolysaccharide core biosynthesis glycosyl transferase LpsC 5.0e-15 ●●●○○ -2.11 -2.1071237360641
Escherichia coli M12  CO715_19960  ATI07793.1  424 aa ATP-dependent Clp protease ATP-binding subunit ClpX 8.4e-5 ●●●○○ -2.11 -2.10639964862779
Escherichia coli O157:H7 str. EDL933  Z5869  AAG59456.1  407 aa orf, hypothetical protein 0.019 ●●●○○ -2.11 -2.10625489492229
Mycobacterium avium subsp. paratuberculosis K10  MAP_1686  AAS04003.1  Q73ZB7  323 aa hypothetical protein 0.014 ●●●○○ -2.1 -2.10442785174646
Vibrio parahaemolyticus RIMD 2210633  VP_1509  BAC59772.1  Q87PJ3  209 aa hypothetical protein 0.038 ●●●○○ -2.1 -2.10397230604534
Escherichia coli M12  CO715_07045  ATI05492.1  99 aa hypothetical protein 0.00043 ●●●○○ -2.1 -2.1038958964568
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2912  WP_014343883.1  E8XK19  iroN  110 aa hypothetical protein 6.7e-5 ●●●○○ -2.1 -2.10316216384123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4273  AIK82817.1  420 aa diaminopimelate decarboxylase 3.8e-15 ●●●○○ -2.1 -2.10214927118889
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2833  AIK81422.1  128 aa cytochrome b 5.5e-7 ●●●○○ -2.1 -2.10148834443889
Escherichia coli O157:H7 str. EDL933  Z5126  AAG58839.1  512 aa escC 0.02 ●●●○○ -2.1 -2.10134800936291
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2326  WP_000639473.1  E8XDS1  oafA  609 aa acyltransferase 8.8e-31 ●●●○○ -2.1 -2.10081359728388
Haemophilus influenzae Rd KW20  HI_1698  NP_439840.1  O05083  353 aa lipopolysaccharide biosynthesis protein 0.037 ●●●○○ -2.1 -2.10001311936892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0360  CBW16460.1  A0A0H3N9R6  yahN  210 aa RhtC-like transporter 0.0014 ●●●○○ -2.1 -2.10001139051818
Acinetobacter baumannii ATCC 17978  A1S_2350  ABO12769.2  A3M775  ubiC  169 aa chorismate pyruvate lyase 3.1e-7 ●●●○○ -2.1 -2.09972787120969
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4604  WP_000934974.1  E8XAT2  ytfL  447 aa HlyC/CorC family transporter 4.3e-5 ●●●○○ -2.1 -2.09938912686728
Vibrio parahaemolyticus RIMD 2210633  VP_1389  BAC59652.1  Q87PW1  375 aa hypothetical protein 0.038 ●●●○○ -2.1 -2.09895735428715
Streptococcus pyogenes M1 5448  SP5448_03950  WP_010922423.1  253 aa DUF3169 family protein 0.025 ●●●○○ -2.1 -2.09877413359448
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0115  NP_232516.1  Q9KN50  257 aa hypothetical protein 7.0e-6 ●●●○○ -2.1 -2.09808736074139
Vibrio parahaemolyticus RIMD 2210633  VP_2220  BAC60483.1  Q87ML1  68 aa heme exporter protein D 0.038 ●●●○○ -2.1 -2.09785896463042
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1071  WP_002856616.1  A0A0H3PD29  cobB  233 aa NAD-dependent deacetylase 0.023 ●●●○○ -2.1 -2.09702169085
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4120  WP_010989084.1  E8XIP8  120 aa hypothetical protein 1.1e-14 ●●●○○ -2.1 -2.0961872093752
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0305  WP_000935097.1  E8XIV8  148 aa hypothetical protein 1.4e-8 ●●●○○ -2.1 -2.0958512407928
Escherichia coli O157:H7 str. EDL933  Z3945  AAG57757.1  347 aa hypothetical protein 0.02 ●●●○○ -2.09 -2.09470424522187
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3839  WP_000081340.1  E8XFY1  yiaJ  266 aa IclR family transcriptional regulator YiaJ 7.5e-29 ●●●○○ -2.09 -2.09468510400418
Acinetobacter baumannii ATCC 17978  A1S_1198  ABO11628.1  298 aa putative extracellular nuclease 1.5e-31 ●●●○○ -2.09 -2.09347102059379
Escherichia coli O157:H7 str. EDL933  Z5894  AAG59480.1  367 aa hypothetical protein 0.02 ●●●○○ -2.09 -2.09229237864999
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2162  WP_000880125.1  E8XC31  hisF  258 aa imidazole glycerol phosphate synthase subunit HisF 3.2e-5 ●●●○○ -2.09 -2.09116451474515
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1730  NP_231366.1  Q9KRB2  topA  876 aa DNA topoisomerase I 5.9e-7 ●●●○○ -2.09 -2.09106104772196
Acinetobacter baumannii ATCC 17978  A1S_0912  ABO11344.2  166 aa Ribosomal protein L22 4.6e-15 ●●●○○ -2.09 -2.09103173978368
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0981  WP_000925872.1  E8XDE7  ycbb  613 aa L,D-transpeptidase 2.0e-15 ●●●○○ -2.09 -2.0906816927876
Escherichia coli M12  CO715_09060  ATI05854.1  350 aa 3-deoxy-7-phosphoheptulonate synthase 2.6e-16 ●●●○○ -2.09 -2.08887338343088
Mycobacterium avium subsp. paratuberculosis K10  MAP_4176  AAS06726.1  Q73S99  500 aa hypothetical protein 0.015 ●●●○○ -2.09 -2.08736247332904
Mycobacterium avium subsp. paratuberculosis K10  MAP_0895c  AAS03212.1  Q742E0  375 aa hypothetical protein 0.015 ●●●○○ -2.09 -2.08721053236016
Vibrio parahaemolyticus RIMD 2210633  VP_0974  BAC59237.1  Q87R24  269 aa hypothetical protein 0.039 ●●●○○ -2.09 -2.08702066382441
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3859  WP_000193201.1  E8XG01  mtlR  196 aa MltR family transcriptional regulator 7.6e-16 ●●●○○ -2.09 -2.08611895209129
Escherichia coli M12  CO715_13255  ATI06590.1  489 aa ribonuclease E/G 2.6e-17 ●●●○○ -2.08 -2.08428317111741
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1048  WP_000497441.1  E8XDL1  msgA  63 aa DNA-damage-inducible protein I 2.1e-5 ●●●○○ -2.08 -2.08371811962303
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2775  WP_000079130.1  E8XID0  rluD  326 aa 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 4.5e-5 ●●●○○ -2.08 -2.08362262180009
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0257  WP_002854288.1  A0A0H3PBY5  136 aa RDD family protein 0.024 ●●●○○ -2.08 -2.08352047335
Mycobacterium avium subsp. paratuberculosis K10  MAP_3731c  AAS06281.1  Q73TI7  500 aa hypothetical protein 0.015 ●●●○○ -2.08 -2.0831931259006
Haemophilus influenzae Rd KW20  HI_0407  NP_438569.1  P44691  znuB  261 aa hypothetical protein 0.038 ●●●○○ -2.08 -2.08282215224373
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0103  WP_001103147.1  E8XH08  139 aa DUF4751 domain-containing protein 1.7e-15 ●●●○○ -2.08 -2.081737762264
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0102  WP_000877512.1  E8XH07  206 aa YdcF family protein 9.0e-9 ●●●○○ -2.08 -2.08017170016902
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0056  NP_229715.1  Q9KVT3  aroE  278 aa shikimate 5-dehydrogenase 1.4e-8 ●●●○○ -2.08 -2.07710982970692
Vibrio parahaemolyticus RIMD 2210633  VP_2294  BAC60557.1  Q87MG1  251 aa putative SAM-dependent methyltransferase 0.04 ●●●○○ -2.08 -2.07554919232811
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4569  WP_000899675.1  E8XAP7  356 aa membrane protein 0.00011 ●●●○○ -2.08 -2.07532443109083
Escherichia coli M12  CO715_10170  ATI06034.1  124 aa hypothetical protein 1.0e-14 ●●●○○ -2.07 -2.07426816243346
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2638  WP_000355342.1  E8XGM5  222 aa DUF5066 family protein 0.0024 ●●●○○ -2.07 -2.07414177438157
Mycobacterium avium subsp. paratuberculosis K10  MAP_1471  AAS03788.1  Q73ZY0  141 aa hypothetical protein 0.015 ●●●○○ -2.07 -2.07328481402253
Acinetobacter baumannii ATCC 17978  A1S_2629  ABO13046.2  308 aa site-specific tyrosine recombinase 9.8e-8 ●●●○○ -2.07 -2.07261294085236
Streptococcus pyogenes M1 5448  SP5448_07380  WP_011285428.1  261 aa multidrug ABC transporter permease 0.028 ●●●○○ -2.07 -2.07185671164867
Streptococcus pyogenes M1 5448  SP5448_08520  WP_011285723.1  419 aa RIP metalloprotease RseP 0.039 ●●●○○ -2.07 -2.0708953751506
Escherichia coli CFT073  c2608  AAN81064.1  A0A0H2V8X8  715 aa Hypothetical protein 0.02 ●●●○○ -2.07 -2.07079285334062
Escherichia coli M12  CO715_05415  ATI05216.1  131 aa hypothetical protein 2.0e-13 ●●●○○ -2.07 -2.06884336606299
Mycobacterium avium subsp. paratuberculosis K10  MAP_2199  AAS04516.1  Q73XV9  306 aa hypothetical protein 0.015 ●●●○○ -2.07 -2.06850620275727
Escherichia coli M12  CO715_08660  ATI05779.1  220 aa fructose-6-phosphate aldolase 5.2e-12 ●●●○○ -2.07 -2.0675914899775
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4081  AIK82627.1  91 aa that protects iron-sulfur proteins against oxidative damage <1e-323 ●●●○○ -2.07 -2.06670003563388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1081  AIK79704.1  301 aa bacterial regulatory helix-turn-helix, lysR family protein 0.046 ●●●○○ -2.07 -2.06661356375638
Haemophilus influenzae Rd KW20  HI_0119  NP_438291.1  P44526  znuA  337 aa high-affinity zinc transporter substrate-binding protein 0.04 ●●●○○ -2.07 -2.06538382459892
Mycobacterium avium subsp. paratuberculosis K10  MAP_0632  AAS02949.1  Q743F3  pepC  432 aa PepC 0.016 ●●●○○ -2.06 -2.06495585476602
Mycobacterium avium subsp. paratuberculosis K10  MAP_1534  AAS03851.1  Q73ZR7  secA2  777 aa SecA2 0.016 ●●●○○ -2.06 -2.0647755007901
Haemophilus influenzae Rd KW20  HI_1263  NP_439418.1  P45131  metXA  358 aa homoserine O-acetyltransferase 0.04 ●●●○○ -2.06 -2.0647331170065
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1942  NP_231576.1  Q9KQQ6  folD  311 aa bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2.5e-7 ●●●○○ -2.06 -2.0646231733386
Escherichia coli O157:H7 str. EDL933  Z0025  AAG54324.1  473 aa hypothetical protein 0.021 ●●●○○ -2.06 -2.06454933305387
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0541  WP_002857003.1  A0A0H3PBK5  purS  81 aa phosphoribosylformylglycinamidine synthase, purS protein 0.025 ●●●○○ -2.06 -2.06355277723
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2890  WP_000776032.1  E8XJB5  211 aa 3-hexulose-6-phosphate synthase 3.4e-6 ●●●○○ -2.06 -2.06341300745332
Escherichia coli O157:H7 str. EDL933  Z3190  AAG57087.1  388 aa UDP-glucose 6-dehydrogenase 0.021 ●●●○○ -2.06 -2.06259780993871
Escherichia coli M12  CO715_21110  ATI08006.1  396 aa anaerobic glycerol-3-phosphate dehydrogenase subunit C 1.0e-7 ●●●○○ -2.06 -2.06133210955003
Escherichia coli M12  CO715_04955  ATI05138.1  392 aa hypothetical protein 8.1e-10 ●●●○○ -2.06 -2.06070617150729
Vibrio parahaemolyticus RIMD 2210633  VP_1057  BAC59320.1  Q87QU2  tolQ  232 aa TolQ protein 0.042 ●●●○○ -2.06 -2.05851400184754
Haemophilus influenzae Rd KW20  HI_0329  NP_438493.1  P44641  epmB  338 aa hypothetical protein 0.04 ●●●○○ -2.06 -2.05833762532203
Escherichia coli O157:H7 str. EDL933  Z4091  AAG57889.1  232 aa orf; hypothetical protein 0.022 ●●●○○ -2.06 -2.058196640676
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2441  WP_000901812.1  E8XEZ7  147 aa PTS sugar transporter subunit IIA 1.4e-15 ●●●○○ -2.06 -2.05757406069366
Mycobacterium avium subsp. paratuberculosis K10  MAP_0757  AAS03074.1  Q742S8  260 aa hypothetical protein 0.016 ●●●○○ -2.06 -2.05630707312893
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1385  WP_001000510.1  E8XH74  297 aa alpha/beta fold hydrolase 7.8e-13 ●●●○○ -2.06 -2.05592976175849
Haemophilus influenzae Rd KW20  HI_0187b  NP_438356.1  P57047  tatB  186 aa sec-independent translocase 0.041 ●●●○○ -2.05 -2.05452648110666
Vibrio parahaemolyticus RIMD 2210633  VP_0574  BAC58837.1  Q87S50  734 aa phosphate ABC transporter, permease protein 0.042 ●●●○○ -2.05 -2.05404419612649
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1181  NP_230826.1  Q9KSS5  595 aa cysteine/glutathione ABC transporter membrane/ATP-binding protein 4.2e-10 ●●●○○ -2.05 -2.05274406394208
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0219  NP_229876.1  Q9KVC7  rpmG  55 aa 50S ribosomal protein L33 6.8e-7 ●●●○○ -2.05 -2.05076211572385
Retrieved entries 1,601–1,700 out of 36,363 total in 520 ms (Link to these results)