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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3231  AIK81792.1  883 aa ppc <1e-323 ●●○○○ -1.42 -1.41711708972644
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4143  AIK82689.1  129 aa glycine cleavage system H protein 1.3e-5 ●●○○○ -1.41 -1.41323467345877
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4526  AIK83064.1  302 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●●○○○ -1.41 -1.41110298246269
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4572  AIK83110.1  152 aa hypothetical protein 0.0021 ●●○○○ -1.41 -1.4096934832272
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5047  AIK83573.1  296 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●●○○○ -1.4 -1.40215308757538
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5106  AIK83632.1  40 aa hypothetical protein 0.012 ●●○○○ -1.4 -1.39511585167627
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2409  AIK81006.1  487 aa type II secretion system protein E 0.0076 ●●○○○ -1.4 -1.39500564995076
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3080  AIK81665.1  309 aa homoserine O-succinyltransferase <1e-323 ●●○○○ -1.39 -1.3920040404547
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3631  AIK82187.1  185 aa putative periplasmic protein <1e-323 ●●○○○ -1.38 -1.38300357525479
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4697  AIK83231.1  156 aa thiol peroxidase 2.5e-13 ●●○○○ -1.38 -1.3821924546449
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4786  AIK83313.1  253 aa mlaA <1e-323 ●●○○○ -1.38 -1.38057863613742
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3459  AIK82015.1  81 aa cell division factor ZapB <1e-323 ●●○○○ -1.37 -1.37394586649902
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4112  AIK82658.1  249 aa short chain dehydrogenase family protein <1e-323 ●●○○○ -1.36 -1.35983862796318
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1532  AIK80152.1  37 aa hypothetical protein <1e-323 ●●○○○ -1.36 -1.3557477405871
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4330  AIK82875.1  195 aa precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 1.1e-16 ●●○○○ -1.36 -1.35548342031724
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4113  AIK82659.1  262 aa bacterial transcriptional regulator family protein <1e-323 ●●○○○ -1.35 -1.34960522618843
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1694  AIK80314.1  204 aa flavin reductase like domain protein 2.5e-7 ●●○○○ -1.35 -1.34932999825355
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4308  AIK82853.1  370 aa iron-containing alcohol dehydrogenase family protein 0.0015 ●●○○○ -1.34 -1.34415685327023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1802  AIK80414.1  427 aa citrate (Si)-synthase <1e-323 ●●○○○ -1.34 -1.3423843254748
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1750  AIK80370.1  244 aa putative transcriptional regulator predicted DNA-binding transcriptional regulator 5.3e-13 ●●○○○ -1.34 -1.33929241306998
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3326  AIK81883.1  146 aa flavodoxin family protein <1e-323 ●●○○○ -1.34 -1.33801262153476
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2878  AIK81467.1  354 aa phosphodiesterase / predicted L-ascorbate 6-phosphate lactonase <1e-323 ●●○○○ -1.33 -1.33297293799521
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4035  AIK82582.1  131 aa hypothetical protein 2.4e-12 ●●○○○ -1.32 -1.32317143927338
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3834  AIK82384.1  209 aa bacterial regulatory, gntR family protein <1e-323 ●●○○○ -1.32 -1.31951874340471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3050  AIK81635.1  95 aa putative cheW domain protein 2.3e-8 ●●○○○ -1.31 -1.30571508088476
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4339  AIK82884.1  93 aa cobalt transport family protein 0.0015 ●●○○○ -1.3 -1.30117788583416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4368  AIK82911.1  340 aa ABC transporter family protein 4.2e-9 ●●○○○ -1.3 -1.3003434921054
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2432  AIK81029.1  255 aa ABC-2 type transporter family protein 1.3e-12 ●●○○○ -1.29 -1.29117152795504
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3049  AIK81634.1  369 aa malK <1e-323 ●●○○○ -1.29 -1.28504996583458
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2225  AIK80831.1  140 aa hypothetical protein 0.003 ●●○○○ -1.28 -1.28296209468189
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1361  AIK79984.1  336 aa beta-hexosaminidase 7.0e-8 ●●○○○ -1.28 -1.28264174631499
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3392  AIK81949.1  95 aa ilvN <1e-323 ●●○○○ -1.28 -1.28225944618768
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1738  AIK80358.1  318 aa formimidoylglutamase 0.016 ●●○○○ -1.28 -1.27808780558371
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4419  AIK82962.1  475 aa phenolic acid decarboxylase subunit C 2.9e-9 ●●○○○ -1.27 -1.27179753161403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4806  AIK83333.1  219 aa hypothetical protein 6.7e-16 ●●○○○ -1.27 -1.26755289332663
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4129  AIK82675.1  285 aa mechanosensitive channel MscS <1e-323 ●●○○○ -1.26 -1.26467011567006
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3923  AIK82471.1  128 aa hypothetical protein 0.00023 ●●○○○ -1.26 -1.26431433506248
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2298  AIK80902.1  263 aa deoC/LacD aldolase family protein 2.8e-6 ●●○○○ -1.26 -1.25926560454075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3373  AIK81930.1  137 aa small heat shock protein IbpA 3.2e-10 ●●○○○ -1.26 -1.25826073143152
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4138  AIK82684.1  164 aa yecA family protein 0.00028 ●●○○○ -1.25 -1.25167128484103
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2777  AIK81366.1  337 aa inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 0.00024 ●●○○○ -1.25 -1.24608434638149
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4013  AIK82560.1  206 aa bacterial SH3 domain protein 1.6e-11 ●●○○○ -1.25 -1.24533302873974
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3031  AIK81616.1  359 aa alanine racemase <1e-323 ●●○○○ -1.25 -1.24529000694597
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2048  AIK80654.1  146 aa hypothetical protein 2.0e-6 ●●○○○ -1.24 -1.24212436223931
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2915  AIK81501.1  119 aa fumarate reductase membrane protein 2.3e-8 ●●○○○ -1.24 -1.24189014223352
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4326  AIK82871.1  458 aa cobyrinic acid a,c-diamide synthase 4.9e-8 ●●○○○ -1.24 -1.23702846600945
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2534  AIK81131.1  382 aa carA 4.2e-8 ●●○○○ -1.23 -1.23084520434582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2614  AIK81208.1  207 aa bglJ transcriptional regulator domain protein 5.8e-15 ●●○○○ -1.22 -1.21543005321497
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1030  AIK79653.1  308 aa phenylacetic acid degradation operon negative regulatory protein PaaX <1e-323 ●●○○○ -1.21 -1.21305107295786
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3133  AIK81705.1  204 aa putative elongation factor <1e-323 ●●○○○ -1.21 -1.21202313555184
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3229  AIK81790.1  334 aa N-acetyl-gamma-glutamyl-phosphate reductase <1e-323 ●●○○○ -1.21 -1.21090579248895
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4109  AIK82655.1  107 aa rieske [2Fe-2S] domain protein 1.6e-14 ●●○○○ -1.21 -1.21007469077527
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3259  AIK81820.1  224 aa hypothetical protein 3.6e-10 ●●○○○ -1.21 -1.20978386749333
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3162  AIK81734.1  316 aa magnesium and cobalt transport protein CorA <1e-323 ●●○○○ -1.2 -1.20308491886529
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4122  AIK82668.1  546 aa thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 9.8e-14 ●●○○○ -1.2 -1.20064683272384
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3852  AIK82402.1  472 aa glutamate synthase (NADPH) small chain glutamatesynthase, small subunit <1e-323 ●●○○○ -1.2 -1.2005304649366
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1972  AIK80578.1  297 aa binding-protein-dependent transport system innermembrane component family protein 3.4e-5 ●●○○○ -1.2 -1.19936578365059
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3545  AIK82101.1  104 aa ysaB-like lipofamily protein 2.9e-6 ●●○○○ -1.2 -1.19909054418972
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4361  AIK82904.1  378 aa lactaldehyde reductase 9.4e-12 ●●○○○ -1.19 -1.19311353782882
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2923  AIK81509.1  706 aa ABC transporter family protein 4.8e-13 ●●○○○ -1.18 -1.18425077907491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3628  AIK82183.1  112 aa hypothetical protein 4.4e-16 ●●○○○ -1.18 -1.18305989625813
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1707  AIK80327.1  219 aa transcriptional repressor 0.0074 ●●○○○ -1.18 -1.18110449420628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1582  AIK80202.1  96 aa doxX family protein <1e-323 ●●○○○ -1.18 -1.18069691496491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1098  AIK79721.1  214 aa hypothetical protein 0.0036 ●●○○○ -1.18 -1.18063714044282
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3976  AIK82525.1  176 aa cob(I)alamin adenosyltransferase <1e-323 ●●○○○ -1.18 -1.1797522784615
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4838  AIK83365.1  224 aa nuoB <1e-323 ●●○○○ -1.18 -1.17883987700806
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4172  AIK82717.1  462 aa sugar (and other) transporter family protein 1.0e-6 ●●○○○ -1.17 -1.17085177785009
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2363  AIK80960.1  84 aa modulator of Rho-dependent transcription termination 1.8e-12 ●●○○○ -1.17 -1.17056165973334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2393  AIK80990.1  207 aa hypothetical protein 0.00038 ●●○○○ -1.17 -1.16801668278664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2937  AIK81523.1  107 aa copper binding protein CutA <1e-323 ●●○○○ -1.17 -1.16779396323001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2590  AIK81187.1  338 aa lipoate-protein ligase A <1e-323 ●●○○○ -1.17 -1.16662138683095
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2571  AIK81168.1  309 aa homoserine kinase <1e-323 ●●○○○ -1.17 -1.16614188984443
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3136  AIK81708.1  387 aa acetyl-CoA C-acyltransferase FadA 7.5e-13 ●●○○○ -1.16 -1.1646259334418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3408  AIK81965.1  459 aa lamB porin family protein 4.6e-11 ●●○○○ -1.16 -1.1645554105222
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2257  AIK80862.1  52 aa hypothetical protein 3.3e-9 ●●○○○ -1.16 -1.16351415139484
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3579  AIK82134.1  158 aa cellulose synthase subunit D family protein <1e-323 ●●○○○ -1.16 -1.16116304375448
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4432  AIK82975.1  113 aa nitrous oxide-stimulated promoter family protein 4.0e-7 ●●○○○ -1.16 -1.16002458144343
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3244  AIK81805.1  105 aa met Apo-repressor, MetJ family protein 8.3e-8 ●●○○○ -1.15 -1.15358582958416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2753  AIK81343.1  199 aa hypothetical protein 3.8e-15 ●●○○○ -1.15 -1.15345247107761
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4028  AIK82575.1  275 aa calcineurin-like phosphoesterase family protein 0.00053 ●●○○○ -1.15 -1.1527808329847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3874  AIK82424.1  183 aa mlaD 2.0e-7 ●●○○○ -1.14 -1.13927415379628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3303  AIK81864.1  207 aa DSBA-like thioredoxin domain protein 0.0038 ●●○○○ -1.14 -1.13887267800632
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1602  AIK80222.1  317 aa potH 2.3e-6 ●●○○○ -1.13 -1.13176969185565
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2328  AIK80933.1  255 aa glutamine amidotransferase domain protein <1e-323 ●●○○○ -1.13 -1.13172320333761
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2411  AIK81008.1  144 aa type II secretion system protein G 0.039 ●●○○○ -1.12 -1.12478160230864
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4890  AIK83417.1  478 aa magnesium transporter 0.013 ●●○○○ -1.12 -1.12386603119773
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4715  AIK83249.1  111 aa BMC domain protein 0.0015 ●●○○○ -1.12 -1.1228469513278
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4799  AIK83326.1  662 aa tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 0.00018 ●●○○○ -1.12 -1.12084607947159
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2957  AIK81542.1  123 aa plasmid stability family protein 3.6e-5 ●●○○○ -1.12 -1.11922670211382
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3198  AIK81766.1  240 aa hypothetical protein <1e-323 ●●○○○ -1.12 -1.11667584602847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1853  AIK80459.1  241 aa ABC transporter family protein 2.4e-9 ●●○○○ -1.12 -1.11638043442519
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2435  AIK81032.1  178 aa hypoxanthine phosphoribosyltransferase 6.6e-5 ●●○○○ -1.11 -1.11248208979857
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4919  AIK83445.1  44 aa hypothetical protein 0.0084 ●●○○○ -1.11 -1.10770626301782
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2163  AIK80768.1  109 aa cytochrome o ubiquinol oxidase subunit IV 5.6e-6 ●●○○○ -1.1 -1.10263480115316
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3433  AIK81990.1  208 aa pyridoxamine 5'-phosphate oxidase family protein 2.6e-6 ●●○○○ -1.1 -1.09863285277341
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3782  AIK82337.1  137 aa large conductance mechanosensitive channel protein 4.0e-6 ●●○○○ -1.1 -1.09774396595102
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3070  AIK81655.1  266 aa manY <1e-323 ●●○○○ -1.09 -1.09056872132086
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5171  AIK83692.1  510 aa phage Terminase family protein 7.9e-12 ●●○○○ -1.09 -1.08865230870694
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4360  AIK82903.1  215 aa L-fuculose phosphate aldolase 0.00053 ●●○○○ -1.09 -1.08537812247002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3339  AIK81896.1  53 aa hypothetical protein 9.0e-6 ●●○○○ -1.08 -1.07968710138191
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