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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0411  NP_230065.1  Q9KUV2  203 aa MSHA pilin protein MshD 0.043 ○○○○○ 0.84 0.841543233286817
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2816  AIK81405.1  91 aa PTS system, Lactose/Cellobiose specific IIB subunit 1.4e-9 ○○○○○ 0.84 0.841592216912318
Acinetobacter baumannii ATCC 17978  A1S_1409  ABO11837.2  245 aa putative short-chain dehydrogenase 0.026 ○○○○○ 0.84 0.841658264898888
Escherichia coli M12  CO715_17160  ATI07293.1  248 aa type I-E CRISPR-associated protein Cas5/CasD 1.4e-14 ○○○○○ 0.84 0.841768532708623
Acinetobacter baumannii ATCC 17978  A1S_0676  ABO11124.1  161 aa putative transposase 0.0085 ○○○○○ 0.84 0.841928808596745
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4961  AIK83487.1  239 aa response regulator 9.5e-6 ○○○○○ 0.84 0.842260302487849
Escherichia coli M12  CO715_20440  ATI07883.1  1024 aa beta-galactosidase 2.3e-8 ○○○○○ 0.84 0.842394470751369
Escherichia coli M12  CO715_11820  ATI06332.1  160 aa transcriptional regulator 0.00053 ○○○○○ 0.84 0.842603116765618
Escherichia coli M12  CO715_16720  ATI07215.1  444 aa PLP-dependent aminotransferase family protein 1.4e-9 ○○○○○ 0.84 0.842811762779867
Acinetobacter baumannii ATCC 17978  A1S_2224  ABO12651.2  201 aa threonine efflux protein 0.011 ○○○○○ 0.84 0.843395993139132
Escherichia coli M12  CO715_23910  ATI08486.1  267 aa pilin chaperone 3.2e-26 ○○○○○ 0.84 0.843437700822613
Escherichia coli M12  CO715_00325  ATI04317.1  396 aa NO-inducible flavohemoprotein 3.8e-8 ○○○○○ 0.84 0.843646346836862
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0969  WP_000705784.1  E8XDD5  ycai  754 aa ComEC family protein 0.0096 ○○○○○ 0.84 0.844177429512688
Escherichia coli M12  CO715_18985  ATI07616.1  337 aa ABC transporter ATP-binding protein 0.023 ○○○○○ 0.84 0.844272284879609
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2550  AIK81147.1  304 aa inosine-uridine preferring nucleoside hydrolase family protein 4.9e-9 ○○○○○ 0.84 0.844474146538163
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1266  AIK79889.1  248 aa scaffolding protein that interacts with murein polymerase and murein hydrolase 1.1e-9 ○○○○○ 0.84 0.844975350591811
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4242  WP_001233463.1  E8XKC7  cpxP  166 aa cell-envelope stress modulator CpxP 0.024 ○○○○○ 0.85 0.845098568675401
Escherichia coli M12  CO715_13230  ATI06585.1  310 aa p-hydroxybenzoic acid efflux pump subunit AaeA 0.012 ○○○○○ 0.85 0.845106868936604
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0120  NP_229779.1  Q9KVM1  hemC  317 aa porphobilinogen deaminase 0.043 ○○○○○ 0.85 0.845389280269111
Escherichia coli M12  CO715_05145  ATI05169.1  554 aa flagellin FliC 0.00062 ○○○○○ 0.85 0.8459414529936
Escherichia coli M12  CO715_20295  ATI07857.1  364 aa DUF1615 domain-containing protein 0.0012 ○○○○○ 0.85 0.846567391036346
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1093  NP_230738.1  Q9KT12  300 aa oligopeptide ABC transporter permease 0.0075 ○○○○○ 0.85 0.846849818219387
Acinetobacter baumannii ATCC 17978  A1S_0207  ABO10683.1  150 aa hypothetical protein 0.005 ○○○○○ 0.85 0.846887266395063
Acinetobacter baumannii ATCC 17978  A1S_0637  ABO11086.2  436 aa DNA-directed DNA polymerase 0.0077 ○○○○○ 0.85 0.847420925712534
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4690  AIK83224.1  401 aa uracil-xanthine permease family protein <1e-323 ○○○○○ 0.85 0.84766739438604
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4238  AIK82784.1  168 aa marR family protein 6.2e-7 ○○○○○ 0.85 0.847785043181042
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4986  AIK83512.1  218 aa HAD hydrolase, IA, variant 1 family protein 3.4e-15 ○○○○○ 0.85 0.848191441020823
Acinetobacter baumannii ATCC 17978  A1S_0531  ABO10984.2  352 aa putative GTPase 0.027 ○○○○○ 0.85 0.848201334485197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2772  AIK81361.1  274 aa phosphohydrolase 2.9e-14 ○○○○○ 0.85 0.848642522910036
Escherichia coli M12  CO715_08610  ATI05770.1  109 aa transcriptional regulator 2.9e-12 ○○○○○ 0.85 0.849279789221582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1517  AIK80137.1  263 aa ssuC 0.02 ○○○○○ 0.85 0.849440670831761
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4439  WP_000235551.1  E8X907  qor  327 aa quinone oxidoreductase 0.0096 ○○○○○ 0.85 0.850244759462334
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0786  NP_230435.1  Q9KTV1  dadA  421 aa D-amino acid dehydrogenase small subunit 0.00028 ○○○○○ 0.85 0.850479525798142
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4654  WP_001738655.1  E8XBK9  mgtA  902 aa magnesium-translocating P-type ATPase 0.0086 ○○○○○ 0.85 0.850811262236314
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0298  NP_232694.1  Q9K315  83 aa hypothetical protein 0.0022 ○○○○○ 0.85 0.850960443854319
Acinetobacter baumannii ATCC 17978  A1S_1736  ABO12163.2  473 aa putative membrane protein 0.0048 ○○○○○ 0.85 0.851104711485948
Escherichia coli M12  CO715_03855  ATI04951.1  297 aa ISNCY family transposase 9.8e-22 ○○○○○ 0.85 0.851157603349821
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4924  AIK83450.1  564 aa PTS system, Fru family, IIB component domain protein <1e-323 ○○○○○ 0.85 0.851420908069461
Escherichia coli M12  CO715_14280  ATI06771.1  110 aa acid stress chaperone HdeA 4.9e-16 ○○○○○ 0.85 0.851574895378319
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2334  AIK80938.1  293 aa bacterial regulatory helix-turn-helix, lysR family protein 6.8e-8 ○○○○○ 0.85 0.851659027368733
Escherichia coli M12  CO715_02495  ATI04702.1  463 aa xanthine permease XanP 2.2e-5 ○○○○○ 0.85 0.852409479435315
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4757  AIK83291.1  308 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 0.85 0.852675790809091
Acinetobacter baumannii ATCC 17978  A1S_0618  ABO11067.2  145 aa hypothetical protein 0.041 ○○○○○ 0.85 0.852887485064071
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0286  NP_229941.1  Q9KV71  458 aa gluconate permease 0.00082 ○○○○○ 0.85 0.854503213088609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0428  NP_230082.1  Q9KUT7  145 aa hypothetical protein 0.029 ○○○○○ 0.85 0.854512174968291
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1968  NP_231602.1  Q9KQN0  181 aa transcriptional regulator 0.00083 ○○○○○ 0.85 0.854512619964389
Escherichia coli M12  CO715_16040  ATI07088.1  314 aa ISNCY family transposase 0.0045 ○○○○○ 0.86 0.85512187762055
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0283  NP_229939.1  Q9KV73  225 aa hypothetical protein 0.0028 ○○○○○ 0.86 0.855891586391336
Escherichia coli M12  CO715_00535  ATI04353.1  113 aa hypothetical protein 0.034 ○○○○○ 0.86 0.856373753706043
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0616  NP_230265.1  Q9KUA7  331 aa peptide ABC transporter ATP-binding protein 0.00025 ○○○○○ 0.86 0.857068939787063
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1199  WP_000480277.1  E8XEX0  ycfH  265 aa metal-dependent hydrolase 0.01 ○○○○○ 0.86 0.857141149400577
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3028  AIK81613.1  138 aa hypothetical protein <1e-323 ○○○○○ 0.86 0.857854602787652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4689  AIK83223.1  208 aa uracil phosphoribosyltransferase 2.2e-10 ○○○○○ 0.86 0.859222871049139
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0538  NP_230189.1  Q9KUI3  333 aa thiosulfate ABC transporter substrate-binding protein 0.0058 ○○○○○ 0.86 0.859690297315486
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4466  WP_000354963.1  E8X9S1  295 aa LysR family transcriptional regulator 0.02 ○○○○○ 0.86 0.859871654279554
Escherichia coli M12  CO715_08055  ATI05668.1  870 aa aminopeptidase N 4.5e-7 ○○○○○ 0.86 0.86054667399102
Escherichia coli M12  CO715_21485  ATI08073.1  278 aa S-formylglutathione hydrolase 0.0028 ○○○○○ 0.86 0.86054667399102
Acinetobacter baumannii ATCC 17978  A1S_2042  ABO12469.2  190 aa putative transcriptional regulator (TetR family) 0.027 ○○○○○ 0.86 0.860591185238406
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1052  NP_230697.1  Q9KT53  132 aa hypothetical protein 0.016 ○○○○○ 0.86 0.860602819408158
Acinetobacter baumannii ATCC 17978  A1S_0627  ABO11076.2  460 aa hypothetical protein 0.0051 ○○○○○ 0.86 0.86068933141353
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1206  NP_230851.1  Q9KSQ0  236 aa histidine utilization repressor 0.0011 ○○○○○ 0.86 0.860729141218165
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0351  NP_230005.1  Q9KV07  68 aa hypothetical protein 3.6e-5 ○○○○○ 0.86 0.860764539569225
Acinetobacter baumannii ATCC 17978  A1S_3388  ABO13777.2  373 aa hypothetical protein 0.0037 ○○○○○ 0.86 0.860923089702658
Acinetobacter baumannii ATCC 17978  A1S_0656  ABO11105.1  309 aa hypothetical protein 0.0061 ○○○○○ 0.86 0.861270712782368
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1622  NP_231261.1  Q9KRL5  212 aa hypothetical protein 0.00065 ○○○○○ 0.86 0.861338358211787
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4295  WP_001128495.1  E8XL67  ptsA  833 aa phosphoenolpyruvate--protein phosphotransferase 0.017 ○○○○○ 0.86 0.862606963858342
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0389  NP_230043.1  Q9KUX0  444 aa Na+/H+ antiporter 0.0016 ○○○○○ 0.86 0.862612783484781
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1040  NP_233422.1  Q9KKR2  298 aa amino acid ABC transporter permease 0.0036 ○○○○○ 0.86 0.862667488068329
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0983  WP_001109471.1  E8XDE9  ycbL  215 aa MBL fold metallo-hydrolase 0.012 ○○○○○ 0.86 0.862680748613418
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0216  NP_229873.1  Q9KVD0  564 aa methyl-accepting chemotaxis protein 0.0041 ○○○○○ 0.86 0.86323809700445
Escherichia coli M12  CO715_20405  ATI07878.1  269 aa 2-keto-4-pentenoate hydratase 0.01 ○○○○○ 0.86 0.863259072176255
Escherichia coli M12  CO715_18395  ATI07515.1  350 aa adenine DNA glycosylase 8.9e-5 ○○○○○ 0.86 0.863467718190504
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4584  AIK83122.1  233 aa hypothetical protein <1e-323 ○○○○○ 0.86 0.863546503252402
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1050  AIK79673.1  879 aa dicarboxylate transport family protein 7.7e-6 ○○○○○ 0.86 0.864285624549153
Escherichia coli M12  CO715_14985  ATI06903.1  677 aa choline transporter 1.1e-9 ○○○○○ 0.86 0.8643023022475
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0694  NP_233081.1  Q9KLP9  151 aa hypothetical protein 0.00079 ○○○○○ 0.86 0.8643959059477
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1296  NP_230941.1  Q9KSG0  282 aa phosphomethylpyrimidine kinase 0.003 ○○○○○ 0.86 0.864675176590075
Escherichia coli M12  CO715_21605  ATI08093.1  195 aa YIP1 family protein 3.0e-16 ○○○○○ 0.86 0.864719594275997
Escherichia coli M12  CO715_17775  ATI07405.1  567 aa EscC/YscC/HrcC family type III secretion system outer membrane ring protein 4.0e-15 ○○○○○ 0.87 0.865136886304495
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1526  NP_231166.1  Q9KRV8  mobA  203 aa molybdopterin-guanine dinucleotide biosynthesis protein MobA 5.3e-6 ○○○○○ 0.87 0.86515821772577
Escherichia coli M12  CO715_13355  ATI06608.1  220 aa acrEF/envCD operon transcriptional regulator 1.3e-10 ○○○○○ 0.87 0.865345532318744
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0898  NP_230545.1  Q9KTK4  xni  283 aa exonuclease IX 1.1e-5 ○○○○○ 0.87 0.865356414889342
Escherichia coli M12  CO715_13005  ATI06544.1  325 aa calcium/sodium antiporter 0.013 ○○○○○ 0.87 0.865554178332993
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2434  NP_232064.1  Q9KPD6  148 aa hypothetical protein 0.02 ○○○○○ 0.87 0.866729452491539
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4745  AIK83279.1  279 aa pyridoxal kinase 3.6e-14 ○○○○○ 0.87 0.867414686397077
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0554  NP_230205.1  Q9KUG7  952 aa insulinase family protease/insulinase family protease 0.027 ○○○○○ 0.87 0.867577768733836
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4184  AIK82729.1  197 aa ABC transporter family protein <1e-323 ○○○○○ 0.87 0.868198405140005
Acinetobacter baumannii ATCC 17978  A1S_0672  ABO11120.2  245 aa Resolvase 0.041 ○○○○○ 0.87 0.868350435417334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1716  AIK80336.1  214 aa inhibitor of apoptosis-promoting Bax1 family protein 1.5e-11 ○○○○○ 0.87 0.868364221766892
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0893  NP_233278.2  Q9KL55  127 aa hypothetical protein 0.00045 ○○○○○ 0.87 0.868855757329039
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1179  AIK79802.1  890 aa aconitate hydratase 1 <1e-323 ○○○○○ 0.87 0.869510997460645
Escherichia coli M12  CO715_09410  ATI05909.1  557 aa potassium-transporting ATPase A chain 2.3e-7 ○○○○○ 0.87 0.86972709861797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1308  AIK79931.1  468 aa bacterial Cytochrome Ubiquinol Oxidase family protein 0.039 ○○○○○ 0.87 0.871358067184888
Porphyromonas gingivalis ATCC 33277  PGN_2025  WP_012458694.1  B2RME8  232 aa RloB domain-containing protein <1e-323 ○○○○○ 0.87 0.871405548338249
Porphyromonas gingivalis ATCC 33277  PGN_1933  WP_012458619.1  B2RM57  414 aa hypothetical protein 0.037 ○○○○○ 0.87 0.871405548338249
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2817  AIK81406.1  247 aa helix-turn-helix domain, rpiR family protein <1e-323 ○○○○○ 0.87 0.871845131794102
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1347  AIK79970.1  303 aa N-acetyl-D-glucosamine kinase <1e-323 ○○○○○ 0.87 0.87200139088682
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2742  AIK81332.1  449 aa PLD-like domain protein <1e-323 ○○○○○ 0.87 0.87221955187266
Escherichia coli M12  CO715_17750  ATI07400.1  291 aa type III secretion protein 1.7e-24 ○○○○○ 0.87 0.872856788831703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1881  AIK80487.1  142 aa universal stress protein UP12 <1e-323 ○○○○○ 0.87 0.873616934578837
Retrieved entries 33,801–33,900 out of 36,363 total in 1064.4 ms (Link to these results)