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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0603  WP_001196903.1  E8X954  372 aa glutamate--cysteine ligase 0.0017 ○○○○○ 1.02 1.01699792267804
Acinetobacter baumannii ATCC 17978  A1S_1603  ABO12030.1  137 aa Biopolymer transport protein ExbD/TolR 0.03 ○○○○○ 1.02 1.01708096436412
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0326  WP_000333387.1  E8XJL4  yafJ  255 aa class II glutamine amidotransferase 0.04 ○○○○○ 1.02 1.0179581008057
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0659  NP_233048.1  Q9KLT2  207 aa protein F-like protein 0.0037 ○○○○○ 1.02 1.01849303301438
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1731  NP_231367.1  Q9KRB1  82 aa hypothetical protein 0.00012 ○○○○○ 1.02 1.01862689661204
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2787  AIK81376.1  269 aa putative inner membrane protein <1e-323 ○○○○○ 1.02 1.01869698631585
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3978  WP_000147832.1  E8XHN8  yidF  176 aa radical SAM protein 0.031 ○○○○○ 1.02 1.01898542892353
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3053  WP_000202726.1  E8XL41  498 aa gluconate permease 0.026 ○○○○○ 1.02 1.01961493184375
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2917  WP_001059352.1  E8XK23  nixA  337 aa HoxN/HupN/NixA family nickel/cobalt transporter 0.045 ○○○○○ 1.02 1.01986648633734
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0182  NP_232582.1  Q9KMY4  530 aa anaerobic nitric oxide reductase transcriptional regulator 0.024 ○○○○○ 1.02 1.01990995145517
Porphyromonas gingivalis ATCC 33277  PGN_0192  WP_012457316.1  B2RH66  1099 aa DUF2723 domain-containing protein 0.026 ○○○○○ 1.02 1.02060329516033
Escherichia coli M12  CO715_13870  ATI06698.1  647 aa 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1.0e-71 ○○○○○ 1.02 1.02078681293415
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0159  WP_000331771.1  E8XH62  pdhR  254 aa pyruvate dehydrogenase complex transcriptional repressor PdhR 0.032 ○○○○○ 1.02 1.02095785634675
Escherichia coli M12  CO715_17065  ATI07275.1  475 aa UbiD family decarboxylase 3.9e-5 ○○○○○ 1.02 1.02120410496264
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5165  AIK83686.1  209 aa chitinase class I family protein <1e-323 ○○○○○ 1.02 1.02142939932408
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1473  CBW17568.1  A0A0H3ND36  pqaA  518 aa PhoPQ-activated protein 0.042 ○○○○○ 1.02 1.02144914902919
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4586  WP_001521305.1  E8XAR4  yjfY  91 aa DUF1471 domain-containing protein 0.042 ○○○○○ 1.02 1.02198625684949
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2757  WP_001526875.1  E8XIB6  yfiE  299 aa LysR family transcriptional regulator 0.038 ○○○○○ 1.02 1.02250673016305
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1456  AIK80077.1  473 aa &gamma-glutamylputrescine synthetase <1e-323 ○○○○○ 1.02 1.02279985745634
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4350  WP_000108413.1  E8XLB0  thiC  631 aa phosphomethylpyrimidine synthase ThiC 0.03 ○○○○○ 1.02 1.02414101878763
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1317  AIK79940.1  237 aa bacterial regulatory, arsR family protein 0.0001 ○○○○○ 1.02 1.02434677261004
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0369  CBW16469.1  A0A0H3NI09  yaiV  207 aa conserved hypothetical protein 0.048 ○○○○○ 1.02 1.02462357137905
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2367  WP_000876078.1  E8XEB3  rcsC  948 aa two-component system sensor histidine kinase RcsC 0.043 ○○○○○ 1.02 1.02497359869141
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1099  NP_230744.1  Q9KT06  152 aa hypothetical protein 4.2e-8 ○○○○○ 1.03 1.02521801362337
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0161  NP_229818.1  Q9KVI5  298 aa DNA-binding transcriptional regulator IlvY 3.8e-7 ○○○○○ 1.03 1.02606907918863
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4661  WP_000514425.1  E8XBL6  467 aa YfcC family protein 0.04 ○○○○○ 1.03 1.02614820913836
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3490  WP_000965023.1  E8XD33  gltB  1486 aa glutamate synthase large subunit 0.031 ○○○○○ 1.03 1.02732876002642
Acinetobacter baumannii ATCC 17978  A1S_0638  ABO11087.2  331 aa hypothetical protein 0.00032 ○○○○○ 1.03 1.02733794661842
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1307  AIK79930.1  336 aa cytochrome d ubiquinol oxidase, subunit II <1e-323 ○○○○○ 1.03 1.02771108398748
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2234  AIK80839.1  67 aa hypothetical protein 5.6e-16 ○○○○○ 1.03 1.02924347027553
Escherichia coli M12  CO715_21970  ATI08162.1  720 aa tyrosine-protein kinase Wzc 1.3e-6 ○○○○○ 1.03 1.02934129951835
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2200  AIK80805.1  193 aa hypothetical protein <1e-323 ○○○○○ 1.03 1.03014911194845
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4910  AIK83436.1  364 aa yejB 3.3e-13 ○○○○○ 1.03 1.03023374582114
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4225  WP_001179685.1  E8XKB0  rhaD  275 aa rhamnulose-1-phosphate aldolase 0.0072 ○○○○○ 1.03 1.03036549181433
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2552  NP_232180.1  Q9KP27  242 aa hypothetical protein 0.021 ○○○○○ 1.03 1.03058490153754
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1226  NP_230871.1  Q9KSN0  tpm  218 aa thiopurine S-methyltransferase 0.00023 ○○○○○ 1.03 1.03078158206162
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1023  WP_077905254.1  E8XDI6  505 aa phage portal protein 0.023 ○○○○○ 1.03 1.03101595012223
Escherichia coli M12  CO715_04995  ATI08728.1  326 aa LPS O-antigen chain length determinant protein WzzB 0.00073 ○○○○○ 1.03 1.03121911364659
Acinetobacter baumannii ATCC 17978  A1S_2086  ABO12513.1  253 aa putative short chain dehydrogenase 0.0029 ○○○○○ 1.03 1.03169708337817
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1223  AIK79846.1  448 aa 6-phospho-beta-glucosidase <1e-323 ○○○○○ 1.03 1.03254411398186
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2448  WP_000986775.1  E8XF04  hisP  258 aa histidine ABC transporter ATP-binding protein HisP 0.039 ○○○○○ 1.03 1.03263973508723
Escherichia coli M12  CO715_16695  ATI07210.1  174 aa rhodanese-like domain-containing protein YgaP 6.5e-28 ○○○○○ 1.03 1.03288828176058
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1891  AIK80497.1  769 aa dimethyl sulfoxide reductase, chain A <1e-323 ○○○○○ 1.03 1.03342489370468
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2368  CBW18470.1  A0A0H3NE19  80 aa conserved hypothetical protein 0.031 ○○○○○ 1.03 1.03390966685539
Acinetobacter baumannii ATCC 17978  A1S_0677  ABO11125.1  55 aa transposase 0.00068 ○○○○○ 1.03 1.03438094806039
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0855  WP_000838671.1  E8XBU2  glnH  248 aa glutamine ABC transporter substrate-binding protein GlnH 0.028 ○○○○○ 1.03 1.03454110415766
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0819  WP_000205518.1  E8XBQ7  bioA  429 aa adenosylmethionine--8-amino-7-oxononanoate transaminase 0.023 ○○○○○ 1.03 1.03466214707179
Escherichia coli M12  CO715_20300  ATI07858.1  406 aa peptide antibiotic transporter SbmA 8.9e-5 ○○○○○ 1.03 1.03476609588882
Escherichia coli M12  CO715_04035  ATI04983.1  292 aa phosphotriesterase-related protein 0.003 ○○○○○ 1.03 1.03476609588882
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0064  WP_000665573.1  E8XG83  citF2  506 aa citrate lyase subunit alpha 0.03 ○○○○○ 1.04 1.03504188297969
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4346  CBW20432.1  A0A0H3NW01  387 aa hypothetical protein 0.043 ○○○○○ 1.04 1.03568266095421
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1661  AIK80281.1  441 aa ribosomal protein S12 methylthiotransferase RimO 5.6e-12 ○○○○○ 1.04 1.03570798625275
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0762  NP_233148.1  Q9KLI2  481 aa hypothetical protein 0.00073 ○○○○○ 1.04 1.0358537880247
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3837  WP_000144381.1  E8XFX9  avtA  416 aa valine--pyruvate transaminase 0.025 ○○○○○ 1.04 1.03669371665217
Acinetobacter baumannii ATCC 17978  A1S_1553  ABO11980.2  211 aa MotA/TolQ/ExbB proton channel 0.0019 ○○○○○ 1.04 1.03674713145816
Escherichia coli M12  CO715_05715  ATI05268.1  127 aa AlpA family phage regulatory protein 4.4e-10 ○○○○○ 1.04 1.03706120204556
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3376  WP_000951049.1  E8XBF0  ygjQ  230 aa vancomycin high temperature exclusion protein 0.012 ○○○○○ 1.04 1.03758960465582
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3724  WP_000624747.1  E8XF69  ugpB  438 aa sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB 0.021 ○○○○○ 1.04 1.03766167411437
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4909  AIK83435.1  341 aa yejE 0.0048 ○○○○○ 1.04 1.03767088296794
Escherichia coli M12  CO715_24605  ATI08610.1  318 aa xanthine dehydrogenase 0.013 ○○○○○ 1.04 1.03831307813105
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1316  AIK79939.1  130 aa ACT domain protein 3.2e-6 ○○○○○ 1.04 1.04026365358246
Escherichia coli M12  CO715_11710  ATI06312.1  56 aa DUF4051 domain-containing protein 5.3e-22 ○○○○○ 1.04 1.04144276834478
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0355  NP_230009.1  Q9KV03  240 aa hypothetical protein 0.017 ○○○○○ 1.04 1.04149632407024
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3472  CBW19567.1  A0A0H3NT19  feoA  75 aa hypothetical ferrous iron transport protein 0.038 ○○○○○ 1.04 1.04150618847579
Acinetobacter baumannii ATCC 17978  A1S_1359  ABO11787.2  345 aa ABC-type Fe3+ transport system 0.036 ○○○○○ 1.04 1.04157639752872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1733  AIK80353.1  158 aa phosphatidylethanolamine-binding family protein <1e-323 ○○○○○ 1.04 1.04203689115522
Acinetobacter baumannii ATCC 17978  A1S_0640  ABO11089.2  314 aa hypothetical protein 0.00015 ○○○○○ 1.04 1.042511803537
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4594  AIK83128.1  883 aa acetyltransferase family protein <1e-323 ○○○○○ 1.04 1.04256165819574
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0751  NP_233137.2  Q9KLJ3  fabH2  362 aa 3-oxoacyl-ACP synthase III 0.0023 ○○○○○ 1.04 1.0426297512048
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0048  NP_229707.1  Q9KVU1  371 aa smf protein 0.0008 ○○○○○ 1.04 1.04331141440917
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3785  WP_001225192.1  E8XFC9  yhjL  1180 aa cellulose biosynthesis protein BcsC 0.0021 ○○○○○ 1.04 1.04350589295708
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0201  WP_001157204.1  E8XHZ0  fhuC  265 aa Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC 0.022 ○○○○○ 1.04 1.04393999332669
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4296  WP_000661597.1  E8XL68  frwC  359 aa PTS fructose transporter subunit EIIC 0.023 ○○○○○ 1.04 1.04413038812543
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3572  CBW19666.1  A0A0H3NMS6  yhjC  299 aa hypothetical lysR-family transcriptional regulator 0.038 ○○○○○ 1.04 1.04416672827654
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0872  WP_001030503.1  E8XBV9  ybiK  313 aa beta-aspartyl-peptidase 0.023 ○○○○○ 1.04 1.04434256713814
Acinetobacter baumannii ATCC 17978  A1S_0625  ABO11074.2  190 aa putative transcriptional regulator (TetR family) 0.00016 ○○○○○ 1.04 1.04440743664825
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2979  WP_000086354.1  E8XK80  ygbD  377 aa NADH:flavorubredoxin reductase NorW 0.028 ○○○○○ 1.04 1.04469912914586
Escherichia coli M12  CO715_15810  ATI07045.1  316 aa magnesium transporter CorA 5.2e-6 ○○○○○ 1.04 1.04498975058701
Escherichia coli M12  CO715_15000  ATI06905.1  490 aa betaine-aldehyde dehydrogenase 1.4e-12 ○○○○○ 1.05 1.04561568862976
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4820  AIK83348.1  297 aa NAD dependent epimerase/dehydratase family protein <1e-323 ○○○○○ 1.05 1.04573601963204
Escherichia coli M12  CO715_22460  ATI08249.1  523 aa cellulose biosynthesis protein BcsE 2.1e-21 ○○○○○ 1.05 1.04582433464401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0649  NP_233038.1  Q9KLU2  180 aa hypothetical protein 0.0034 ○○○○○ 1.05 1.04627475005411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1690  AIK80310.1  219 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein 2.1e-13 ○○○○○ 1.05 1.04650876742925
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1201  AIK79824.1  302 aa bacterial regulatory helix-turn-helix, lysR family protein 1.6e-10 ○○○○○ 1.05 1.04654167085224
Acinetobacter baumannii ATCC 17978  A1S_1221  ABO11651.1  64 aa hypothetical protein 0.041 ○○○○○ 1.05 1.04702732628559
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4234  WP_000566800.1  E8XKB9  435 aa TRAP transporter large permease 0.022 ○○○○○ 1.05 1.04728233975149
Escherichia coli M12  CO715_15320  ATI06963.1  277 aa sulfurtransferase FdhD 9.8e-66 ○○○○○ 1.05 1.047493502758
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2445  WP_000043010.1  E8XF01  yfcF  214 aa glutathione transferase 0.023 ○○○○○ 1.05 1.04770199018895
Escherichia coli M12  CO715_21840  ATI08138.1  259 aa galactitol utilization operon repressor 5.4e-13 ○○○○○ 1.05 1.0479107947865
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0881  CBW16977.1  A0A0H3NEW2  ybjZ  648 aa conserved hypothetical ABC transporter 0.035 ○○○○○ 1.05 1.0491595920061
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2334  NP_231965.1  Q9KPN2  327 aa hypothetical protein 0.00027 ○○○○○ 1.05 1.04927029204949
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1057  NP_233439.1  Q9KKP5  239 aa short chain dehydrogenase/reductase oxidoreductase 0.00052 ○○○○○ 1.05 1.0494250652408
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4344  AIK82889.1  351 aa nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.7e-6 ○○○○○ 1.05 1.04982084978566
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3921  AIK82469.1  191 aa BON domain protein <1e-323 ○○○○○ 1.05 1.0513314135853
Escherichia coli M12  CO715_06925  ATI05471.1  92 aa hypothetical protein 0.00015 ○○○○○ 1.05 1.05166642304298
Porphyromonas gingivalis ATCC 33277  PGN_0211  WP_012457331.1  B2RH85  390 aa ATP-binding protein 2.3e-8 ○○○○○ 1.05 1.05181974555339
Porphyromonas gingivalis ATCC 33277  PGN_0211  WP_080504389.1  B2RH85  48 aa DNA methylase 2.3e-8 ○○○○○ 1.05 1.05181974555339
Acinetobacter baumannii ATCC 17978  A1S_0642  ABO11091.2  352 aa hypothetical protein 0.00011 ○○○○○ 1.05 1.05218282844208
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2031  AIK80637.1  223 aa hypothetical protein 6.8e-10 ○○○○○ 1.05 1.05286997275916
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3517  CBW19611.1  A0A0H3NMP4  ggt  580 aa gamma-glutamyltranspeptidase precursor 0.026 ○○○○○ 1.05 1.05320566655979
Retrieved entries 34,301–34,400 out of 36,363 total in 1076.5 ms (Link to these results)