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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_07485  ATI05570.1  180 aa cell division protein ZapC 0.019 ○○○○○ 1.36 1.35587231181782
Escherichia coli M12  CO715_02810  ATI04762.1  667 aa transketolase 6.3e-42 ○○○○○ 1.36 1.35649824986056
Escherichia coli M12  CO715_03700  ATI04924.1  167 aa DUF1877 domain-containing protein 2.3e-20 ○○○○○ 1.36 1.35733283391756
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1288  NP_230933.1  Q9KSG8  opgG  545 aa glucan biosynthesis protein G 3.9e-7 ○○○○○ 1.36 1.3574366169557
Escherichia coli M12  CO715_20340  ATI07866.1  255 aa taurine transporter ATP-binding subunit 6.4e-17 ○○○○○ 1.36 1.3587933560173
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0497  CBW16597.1  A0A0H3N8J9  ybbN  284 aa thioredoxin-like protein 0.0096 ○○○○○ 1.36 1.3594345935497
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2649  NP_232277.1  Q9KNT2  273 aa serine acetyltransferase 0.0038 ○○○○○ 1.36 1.36002842991075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1087  AIK79710.1  237 aa putative oxidoreductase with NAD(P)-binding Rossmann-fold domain 2.1e-9 ○○○○○ 1.36 1.36089520465677
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1139  CBW17235.1  A0A0H3NC55  ycfH  265 aa conserved hypothetical protein 0.014 ○○○○○ 1.36 1.36261060918649
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5117  AIK83643.1  525 aa 2,3-dihydroxybenzoate-AMP ligase <1e-323 ○○○○○ 1.36 1.36315033150851
Acinetobacter baumannii ATCC 17978  A1S_2037  ABO12464.2  229 aa EsvI 0.0083 ○○○○○ 1.36 1.36362573382029
Acinetobacter baumannii ATCC 17978  A1S_1450  ABO11878.2  228 aa hypothetical protein 0.017 ○○○○○ 1.36 1.36407132183509
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2281  NP_231912.1  Q9KPT1  rimK  301 aa ribosomal protein S6 modification protein 0.0074 ○○○○○ 1.36 1.36442054068497
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0257  NP_232655.1  Q9KMR3  484 aa sensor histidine kinase 5.4e-5 ○○○○○ 1.36 1.36499784164437
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1265  AIK79888.1  284 aa aldo/keto reductase family protein 0.00095 ○○○○○ 1.37 1.36625333835233
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1552  AIK80172.1  285 aa formate transporter FocA <1e-323 ○○○○○ 1.37 1.36674768906488
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2006  WP_000631669.1  E8XAB7  fliK  405 aa flagellar hook length control protein FliK 0.002 ○○○○○ 1.37 1.36738133104106
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2068  NP_231700.1  Q9KQD2  495 aa flagellar biosynthesis regulator FlhF 0.00075 ○○○○○ 1.37 1.36838948955559
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2405  AIK81002.1  1102 aa pullulanase <1e-323 ○○○○○ 1.37 1.36880948024853
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4235  AIK82780.1  202 aa phage integrase family protein <1e-323 ○○○○○ 1.37 1.36936853823951
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5058  AIK83584.1  369 aa S-adenosyl-L-homocysteine hydrolase, NAD bindingdomain protein 3.3e-16 ○○○○○ 1.37 1.37225375244833
Acinetobacter baumannii ATCC 17978  A1S_2522  ABO12939.2  A3M7P5  lepA  605 aa GTP-binding protein 0.0026 ○○○○○ 1.37 1.37298151683459
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1066  CBW17162.1  A0A0H3NFG2  498 aa hypothetical sodium/glucose cotransporter 0.0018 ○○○○○ 1.37 1.37309252122765
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1441  AIK80062.1  130 aa pyrimidine utilization protein C 7.0e-5 ○○○○○ 1.37 1.37461012690629
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2742  WP_000368620.1  E8XHL4  361 aa ParA family protein 0.002 ○○○○○ 1.38 1.37531410283001
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3855  WP_000200179.1  E8XFZ7  selA  463 aa L-seryl-tRNA(Sec) selenium transferase 0.017 ○○○○○ 1.38 1.37603933311027
Escherichia coli M12  CO715_01305  ATI04489.1  219 aa DUF2491 domain-containing protein 4.2e-59 ○○○○○ 1.38 1.37631962121421
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0528  WP_001110598.1  E8X894  ybbA  228 aa ABC transporter ATP-binding protein 0.0014 ○○○○○ 1.38 1.37689976074673
Escherichia coli M12  CO715_21875  ATI08145.1  467 aa two-component system sensor histidine kinase BaeA 6.6e-11 ○○○○○ 1.38 1.37819743534244
Acinetobacter baumannii ATCC 17978  A1S_3106  ABO13503.2  634 aa 1-deoxyxylulose-5-phosphate synthase 0.043 ○○○○○ 1.38 1.37842057288246
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0230  NP_232629.1  Q9KMT9  254 aa iron(III) ABC transporter ATP-binding protein 0.0077 ○○○○○ 1.38 1.37934879962198
Escherichia coli M12  CO715_21550  ATI08086.1  239 aa protein SanA 0.0037 ○○○○○ 1.38 1.37986660345644
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3634  WP_000269311.1  E8XE12  yhfK  695 aa membrane protein 0.0026 ○○○○○ 1.38 1.37987265005993
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4988  AIK83514.1  525 aa bacterial extracellular solute-binding, 5 Middlefamily protein 1.6e-9 ○○○○○ 1.38 1.37987765416164
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0185  NP_232585.1  Q9KMY1  75 aa hypothetical protein 0.029 ○○○○○ 1.38 1.38134736528419
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1054  WP_000053044.1  E8XE19  uup  635 aa ABC transporter ATP-binding protein 0.0016 ○○○○○ 1.38 1.38231108402998
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2971  WP_000199033.1  E8XK72  srlE  323 aa PTS sorbitol transporter subunit IIB 0.0025 ○○○○○ 1.38 1.38236751796087
Escherichia coli M12  CO715_20145  ATI07829.1  193 aa ACP phosphodiesterase 0.00012 ○○○○○ 1.38 1.38237035562742
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1917  CBW18012.1  A0A0H3NCW8  yedI  303 aa conserved hypothetical integral membrane protein 0.0043 ○○○○○ 1.38 1.3828597946996
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1199  AIK79822.1  362 aa tartrate dehydrogenase <1e-323 ○○○○○ 1.38 1.38329980197868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1107  AIK79730.1  163 aa type VI secretion system protein 7.6e-15 ○○○○○ 1.38 1.38388410513253
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0152  NP_229810.1  Q9KVJ2  213 aa DNA-binding transcriptional repressor FabR 0.007 ○○○○○ 1.39 1.3851939427283
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1600  WP_000692042.1  E8XJ35  yncD  706 aa TonB-dependent receptor 4.9e-5 ○○○○○ 1.39 1.38698045094441
Acinetobacter baumannii ATCC 17978  A1S_1522  ABO11949.1  135 aa Predicted redox disulfide bond formation protein OsmC-like protein 0.00042 ○○○○○ 1.39 1.3886936920463
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1941  NP_231575.1  Q9KQQ7  431 aa hypothetical protein 0.031 ○○○○○ 1.39 1.38925195817862
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1882  AIK80488.1  521 aa alkyl hydroperoxide reductase, F subunit <1e-323 ○○○○○ 1.39 1.39078588807734
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2708  WP_000457373.1  E8XHI1  416 aa transposase 0.0033 ○○○○○ 1.39 1.39136465643229
Mycobacterium avium subsp. paratuberculosis K10  MAP_3566  AAS06116.1  Q73U02  488 aa hypothetical protein 0.05 ○○○○○ 1.39 1.39293524915849
Mycobacterium avium subsp. paratuberculosis K10  MAP_3437c  AAS05987.1  Q73UD1  280 aa hypothetical protein 0.05 ○○○○○ 1.39 1.39327972505432
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1201  WP_000008410.1  E8XEX2  fhuE  724 aa ferric-rhodotorulic acid/ferric-coprogen receptor FhuE 0.002 ○○○○○ 1.39 1.3941371806234
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2008  NP_231642.1  Q9KQJ0  481 aa pyruvate kinase II 0.037 ○○○○○ 1.39 1.39423232323379
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0412  NP_230066.1  H9L4R1  256 aa hypothetical protein 0.0028 ○○○○○ 1.39 1.39470991868649
Mycobacterium avium subsp. paratuberculosis K10  MAP_0865  AAS03182.1  Q742H0  423 aa hypothetical protein 0.049 ○○○○○ 1.4 1.39529344013879
Mycobacterium avium subsp. paratuberculosis K10  MAP_0621  AAS02938.1  Q743G4  550 aa hypothetical protein 0.049 ○○○○○ 1.4 1.39534999090126
Escherichia coli M12  CO715_08945  ATI05831.1  346 aa biotin synthase 0.019 ○○○○○ 1.4 1.39718422263909
Porphyromonas gingivalis ATCC 33277  PGN_1043  WP_012457980.1  B2RJL7  263 aa phospholipase 1.7e-6 ○○○○○ 1.4 1.40037325609395
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0178  NP_232578.1  Q9KMY8  217 aa FrnE protein 2.0e-7 ○○○○○ 1.4 1.40152574045715
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3116  WP_000626381.1  E8X8Q5  sdaB  455 aa L-serine ammonia-lyase 0.025 ○○○○○ 1.4 1.40163191563714
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0113  NP_229772.1  Q9KVM8  222 aa methyltransferase-like protein 0.019 ○○○○○ 1.4 1.40200645803219
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3221  WP_001520421.1  E8X9P5  225 aa energy-coupling factor ABC transporter ATP-binding protein 0.026 ○○○○○ 1.4 1.40229099508874
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3220  WP_000553271.1  E8X9P4  235 aa energy-coupling factor transporter transmembrane protein EcfT 0.026 ○○○○○ 1.4 1.40229099508874
Escherichia coli M12  CO715_09590  ATI05937.1  292 aa magnesium and cobalt efflux protein CorC 5.3e-8 ○○○○○ 1.4 1.40260901900956
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4442  WP_000486903.1  E8X910  tyrB  397 aa aromatic amino acid transaminase 0.017 ○○○○○ 1.4 1.40270559934505
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4011  WP_001687378.1  E8XHS0  397 aa mandelate racemase/muconate lactonizing enzyme family protein 0.0015 ○○○○○ 1.4 1.40318633729262
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1414  AIK80036.1  286 aa pirin family protein 0.00012 ○○○○○ 1.4 1.40329932637656
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4133  WP_000339080.1  E8XJE3  rarD  294 aa EamA family transporter RarD 0.0032 ○○○○○ 1.4 1.40384227489015
Escherichia coli M12  CO715_01870  ATI04587.1  223 aa protein NrfC 6.2e-10 ○○○○○ 1.4 1.40386089509505
Mycobacterium avium subsp. paratuberculosis K10  MAP_0886c  AAS03203.1  Q742E9  306 aa hypothetical protein 0.049 ○○○○○ 1.4 1.40390417601829
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0889  WP_000195709.1  E8XCL1  dacC  400 aa serine-type D-Ala-D-Ala carboxypeptidase 0.0031 ○○○○○ 1.4 1.40454963658944
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3110  WP_000890027.1  E8X8P9  yqcB  260 aa tRNA pseudouridine(65) synthase TruC 0.0024 ○○○○○ 1.4 1.40462907668184
Mycobacterium avium subsp. paratuberculosis K10  MAP_4221c  AAS06771.1  Q73S55  441 aa hypothetical protein 0.049 ○○○○○ 1.4 1.40477380737749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1312  AIK79935.1  61 aa hypothetical protein 4.5e-7 ○○○○○ 1.4 1.40499302047174
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3666  AIK82221.1  345 aa hypothetical protein 2.8e-12 ○○○○○ 1.41 1.40517666817042
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2562  WP_001097535.1  E8XFR8  eutA  467 aa ethanolamine ammonia-lyase reactivating factor EutA 0.00076 ○○○○○ 1.41 1.40627413225856
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0883  NP_233269.1  Q9KL64  369 aa motility-associated cytotoxin MakA 0.012 ○○○○○ 1.41 1.40645050177371
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2756  NP_232382.1  Q9KNI3  485 aa potassium uptake protein TrkH 0.0085 ○○○○○ 1.41 1.40656852597553
Escherichia coli M12  CO715_20705  ATI07930.1  94 aa type 1 fimbrial protein 2.7e-10 ○○○○○ 1.41 1.40657329328029
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4718  WP_001033021.1  E8XCG0  yjiN  423 aa DUF445 domain-containing protein 0.0015 ○○○○○ 1.41 1.40695582630838
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1744  WP_000443030.1  E8XKU4  trpA  268 aa tryptophan synthase subunit alpha 0.0015 ○○○○○ 1.41 1.4077496414454
Mycobacterium avium subsp. paratuberculosis K10  MAP_3176  AAS05724.1  Q73V40  fprA  455 aa FprA 0.049 ○○○○○ 1.41 1.40775861535009
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1692  AIK80312.1  731 aa mechanosensitive ion channel family protein 0.00029 ○○○○○ 1.41 1.40831242766345
Mycobacterium avium subsp. paratuberculosis K10  MAP_2339c  AAS04656.1  Q73XH0  145 aa hypothetical protein 0.048 ○○○○○ 1.41 1.41034403422964
Mycobacterium avium subsp. paratuberculosis K10  MAP_1805c  AAS04122.1  Q73YZ8  cobN  1191 aa CobN 0.048 ○○○○○ 1.41 1.41086160867539
Mycobacterium avium subsp. paratuberculosis K10  MAP_3712  AAS06262.1  Q73TK6  narU  463 aa NarU 0.048 ○○○○○ 1.41 1.41229229926913
Porphyromonas gingivalis ATCC 33277  PGN_0175  WP_012457302.1  B2RH49  224 aa YggS family pyridoxal phosphate-dependent enzyme 0.024 ○○○○○ 1.41 1.41299967900062
Mycobacterium avium subsp. paratuberculosis K10  MAP_3740  AAS06290.1  Q73TH8  3068 aa hypothetical protein 0.048 ○○○○○ 1.41 1.41324622941236
Mycobacterium avium subsp. paratuberculosis K10  MAP_1845c  AAS04162.1  Q73YV8  184 aa hypothetical protein 0.048 ○○○○○ 1.41 1.41382057332848
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5177  AIK83698.1  179 aa hypothetical protein 2.6e-7 ○○○○○ 1.41 1.41387328093302
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2829  WP_001086808.1  E8XJ55  201 aa phage tail protein I 0.0041 ○○○○○ 1.41 1.41414309792483
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1073  AIK79696.1  337 aa ABC transporter family protein 0.011 ○○○○○ 1.41 1.41419730956413
Mycobacterium avium subsp. paratuberculosis K10  MAP_1618c  AAS03935.1  Q73ZI5  376 aa hypothetical protein 0.048 ○○○○○ 1.41 1.41422287317761
Escherichia coli M12  CO715_22720  ATI08291.1  440 aa thymidine phosphorylase 0.0036 ○○○○○ 1.42 1.41533642587874
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4616  AIK83150.1  203 aa haloacid dehalogenase-like hydrolase family protein 2.7e-14 ○○○○○ 1.42 1.41551419652019
Escherichia coli M12  CO715_16210  ATI07119.1  247 aa cell division protein ZapD 0.006 ○○○○○ 1.42 1.41658830196424
Acinetobacter baumannii ATCC 17978  A1S_0343  ABO10803.2  949 aa pH adaptation potassium efflux system transmembrane protein 0.0016 ○○○○○ 1.42 1.41678958699039
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3076  WP_000490481.1  E8X8L5  iap  348 aa aminopeptidase 0.00065 ○○○○○ 1.42 1.41761389892347
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1210  WP_000205990.1  E8XEY1  ycfQ  211 aa TetR family copper-responsive transcriptional repressor ComR 0.0023 ○○○○○ 1.42 1.41782017228916
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2380  WP_000857292.1  E8XEC6  glpA  542 aa anaerobic glycerol-3-phosphate dehydrogenase subunit A 0.00093 ○○○○○ 1.42 1.41889949263906
Acinetobacter baumannii ATCC 17978  A1S_1763  ABO12190.2  183 aa putative transcriptional regulator 1.3e-5 ○○○○○ 1.42 1.4206726204263
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2001  AIK80607.1  401 aa major Facilitator Superfamily protein <1e-323 ○○○○○ 1.42 1.42180401929921
Retrieved entries 35,001–35,100 out of 36,363 total in 600 ms (Link to these results)