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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1151  WP_001144632.1  E8XES4  ycea  350 aa rhodanese-related sulfurtransferase 0.043 ●●○○○ -1.24 -1.23670797506224
Escherichia coli M12  CO715_11305  ATI06238.1  252 aa DeoR/GlpR transcriptional regulator 2.0e-9 ●●○○○ -1.24 -1.23571983116729
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4658  WP_000013055.1  E8XBL3  pyrB  311 aa aspartate carbamoyltransferase 0.017 ●●○○○ -1.24 -1.23565644843628
Acinetobacter baumannii ATCC 17978  A1S_0156  ABO10639.2  A3M145  atpC  139 aa membrane-bound ATP synthase F1 sector, epsilon-subunit 0.043 ●●○○○ -1.24 -1.23557681053983
Escherichia coli M12  CO715_08705  ATI05787.1  531 aa ABC-F family ATPase 6.5e-6 ●●○○○ -1.24 -1.23530253913879
Escherichia coli M12  CO715_09245  ATI05880.1  200 aa cob(I)yrinic acid a,c-diamide adenosyltransferase 0.00025 ●●○○○ -1.24 -1.23509389312454
Escherichia coli M12  CO715_21995  ATI08167.1  248 aa colanic acid biosynthesis glycosyltransferase WcaE 5.2e-99 ●●○○○ -1.23 -1.23488524711029
Escherichia coli M12  CO715_18980  ATI07615.1  313 aa spermidine/putrescine ABC transporter permease 2.4e-13 ●●○○○ -1.23 -1.23467660109604
Escherichia coli M12  CO715_17480  ATI07351.1  1180 aa exodeoxyribonuclease V subunit beta 1.9e-11 ●●○○○ -1.23 -1.2344679550818
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0064  CBW16165.1  A0A0H3N7Q8  citG2  297 aa triphosphoribosyl-dephospho-CoA synthase 0.0098 ●●○○○ -1.23 -1.2340848667588
Escherichia coli M12  CO715_19240  ATI08866.1  410 aa sensor domain-containing diguanylate cyclase 3.0e-32 ●●○○○ -1.23 -1.2336333710248
Escherichia coli M12  CO715_16305  ATI07138.1  313 aa ribosomal RNA small subunit methyltransferase H 9.9e-20 ●●○○○ -1.23 -1.23342472501055
Escherichia coli M12  CO715_22500  ATI08256.1  334 aa dipeptide ABC transporter ATP-binding protein 0.0013 ●●○○○ -1.23 -1.23342472501055
Acinetobacter baumannii ATCC 17978  A1S_2566  ABO12983.2  651 aa putative ferric siderophore receptor protein 2.1e-7 ●●○○○ -1.23 -1.23332060855618
Escherichia coli M12  CO715_01745  ATI04564.1  150 aa phosphonate C-P lyase system protein PhnG 9.1e-15 ●●○○○ -1.23 -1.23259014095356
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0049  CBW16150.1  A0A0H3NH14  fkpB  149 aa probable FkbB-type 16 kD peptidyl-prolyl cis-trans isomerase 0.0061 ●●○○○ -1.23 -1.23208466700652
Escherichia coli M12  CO715_19545  ATI07721.1  55 aa hypothetical protein 4.9e-8 ●●○○○ -1.23 -1.23154691088231
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0985  WP_000977713.1  E8XDF1  ompF  363 aa porin OmpF 4.2e-5 ●●○○○ -1.23 -1.23140269480667
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1992  WP_000146802.1  E8XAA3  fliD  467 aa flagellar filament capping protein FliD 2.0e-5 ●●○○○ -1.23 -1.23139236044369
Escherichia coli M12  CO715_06900  ATI05466.1  304 aa metal ABC transporter substrate-binding protein 2.5e-59 ●●○○○ -1.23 -1.23133826486806
Escherichia coli M12  CO715_09025  ATI05847.1  262 aa molybdenum-dependent transcriptional regulator 0.001 ●●○○○ -1.23 -1.23112961885381
Escherichia coli M12  CO715_15490  ATI06991.1  161 aa ribonuclease E activity regulator RraA 4.5e-10 ●●○○○ -1.23 -1.23092097283956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2534  AIK81131.1  382 aa carA 4.2e-8 ●●○○○ -1.23 -1.23084520434582
Escherichia coli M12  CO715_19915  ATI07784.1  152 aa transcriptional regulator 2.1e-18 ●●○○○ -1.23 -1.23071232682532
Escherichia coli M12  CO715_07390  ATI05553.1  220 aa hypothetical protein 1.1e-6 ●●○○○ -1.23 -1.22966909675407
Escherichia coli M12  CO715_13795  ATI06685.1  500 aa sugar ABC transporter ATP-binding protein 4.9e-19 ●●○○○ -1.23 -1.22904315871133
Escherichia coli M12  CO715_20080  ATI07816.1  325 aa thiamine-phosphate kinase 0.011 ●●○○○ -1.23 -1.22904315871133
Streptococcus pyogenes M1 5448  SP5448_00770  WP_010921819.1  394 aa acetyl-CoA C-acetyltransferase 0.032 ●●○○○ -1.23 -1.22876460284584
Escherichia coli M12  CO715_00090  ATI04273.1  281 aa sulfurtransferase 3.1e-51 ●●○○○ -1.23 -1.22862586668283
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0495  NP_232886.1  Q9KM87  290 aa hypothetical protein 4.9e-6 ●●○○○ -1.23 -1.22854988897423
Escherichia coli M12  CO715_15560  ATI07003.1  296 aa methylenetetrahydrofolate reductase 4.0e-13 ●●○○○ -1.23 -1.22841722066858
Escherichia coli M12  CO715_10275  ATI06051.1  404 aa starvation-sensing protein RspA 1.5e-46 ●●○○○ -1.23 -1.22820857465433
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1715  NP_231351.1  Q9KRC7  mukE  247 aa condesin subunit E 6.4e-6 ●●○○○ -1.23 -1.22810393167779
Escherichia coli M12  CO715_19300  ATI07673.1  343 aa mechanosensitive ion channel protein MscS 1.5e-69 ●●○○○ -1.23 -1.22758263661158
Escherichia coli M12  CO715_11285  ATI06235.1  618 aa signal peptide peptidase SppA 2.3e-132 ●●○○○ -1.23 -1.22716534458309
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2548  WP_000517460.1  E8XFQ4  ucpA  263 aa SDR family oxidoreductase UcpA 0.011 ●●○○○ -1.23 -1.22702849235897
Escherichia coli M12  CO715_10085  ATI06024.1  68 aa hypothetical protein 3.9e-24 ●●○○○ -1.23 -1.22695669856884
Escherichia coli M12  CO715_11260  ATI06230.1  651 aa DNA topoisomerase III 0.00028 ●●○○○ -1.23 -1.22633076052609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2501  NP_232130.1  P0C6E1  pepA  503 aa leucyl aminopeptidase 4.2e-7 ●●○○○ -1.23 -1.2263057972728
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4078  WP_001311244.1  E8XIL1  ilvL  32 aa ilv operon leader peptide 0.013 ●●○○○ -1.23 -1.22599624529208
Escherichia coli M12  CO715_05565  ATI05243.1  218 aa carbon-nitrogen hydrolase family protein 0.003 ●●○○○ -1.23 -1.22570482248334
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3729  CBW19821.1  A0A0H3NHI8  mgtC  231 aa Mg(2+) transport ATPase protein C 0.014 ●●○○○ -1.23 -1.22569856475555
Escherichia coli M12  CO715_01295  ATI04487.1  212 aa DUF1190 domain-containing protein 3.7e-7 ●●○○○ -1.23 -1.22528753045485
Escherichia coli M12  CO715_19525  ATI07717.1  254 aa phosphatidylglycerophosphatase B 4.4e-6 ●●○○○ -1.22 -1.22445294639785
Escherichia coli M12  CO715_02830  ATI04765.1  111 aa ethanolamine utilization protein EutS 5.9e-15 ●●○○○ -1.22 -1.2242443003836
Escherichia coli M12  CO715_13345  ATI06607.1  294 aa adenine-specific DNA-methyltransferase 9.4e-7 ●●○○○ -1.22 -1.2238270083551
Escherichia coli M12  CO715_13755  ATI06677.1  154 aa anaerobic ribonucleoside-triphosphate reductase-activating protein 9.5e-13 ●●○○○ -1.22 -1.22361836234085
Escherichia coli M12  CO715_04855  ATI05120.1  949 aa two-component system sensor histidine kinase RcsC 1.0e-34 ●●○○○ -1.22 -1.22340971632661
Escherichia coli M12  CO715_09430  ATI05913.1  225 aa two-component system response regulator KdpE 2.6e-10 ●●○○○ -1.22 -1.22340971632661
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0023  CBW16124.1  A0A0H3N7J0  bcfC  873 aa fimbrial usher protein 0.0094 ●●○○○ -1.22 -1.22334197459004
Escherichia coli M12  CO715_05680  ATI05261.1  106 aa hypothetical protein 5.7e-41 ●●○○○ -1.22 -1.22320107031236
Escherichia coli M12  CO715_15630  ATI07017.1  883 aa phosphoenolpyruvate carboxylase 7.1e-25 ●●○○○ -1.22 -1.22174054821262
Escherichia coli M12  CO715_05030  ATI05152.1  356 aa histidinol-phosphate transaminase 1.1e-16 ●●○○○ -1.22 -1.22132325618412
Escherichia coli M12  CO715_04065  ATI04989.1  268 aa nitrite transporter NirC 0.036 ●●○○○ -1.22 -1.22132325618412
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1770  WP_000193432.1  E8XKX0  hnr  337 aa two-component system response regulator RssB 0.0049 ●●○○○ -1.22 -1.22119746878403
Escherichia coli M12  CO715_17700  ATI07390.1  110 aa hypothetical protein 2.5e-41 ●●○○○ -1.22 -1.22069731814137
Escherichia coli M12  CO715_21820  ATI08135.1  150 aa PTS galactitol transporter subunit IIA 2.5e-102 ●●○○○ -1.22 -1.22028002611287
Escherichia coli M12  CO715_16165  ATI07111.1  284 aa protein AmpE 1.1e-7 ●●○○○ -1.22 -1.22007138009862
Escherichia coli M12  CO715_10920  ATI06164.1  254 aa electron transfer flavoprotein 0.0006 ●●○○○ -1.22 -1.22007138009862
Porphyromonas gingivalis ATCC 33277  PGN_1790  WP_004583522.1  B2RLR4  117 aa DUF2023 family protein 1.4e-10 ●●○○○ -1.22 -1.21988490954807
Escherichia coli M12  CO715_21685  ATI08109.1  759 aa hypothetical protein 2.7e-44 ●●○○○ -1.22 -1.21840221198463
Escherichia coli M12  CO715_21560  ATI08088.1  231 aa CidB/LrgB family autolysis modulator 0.0039 ●●○○○ -1.22 -1.2161071058279
Escherichia coli M12  CO715_20670  ATI07925.1  129 aa curli production assembly/transport component CsgE 1.6e-26 ●●○○○ -1.22 -1.21589845981365
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2614  AIK81208.1  207 aa bglJ transcriptional regulator domain protein 5.8e-15 ●●○○○ -1.22 -1.21543005321497
Escherichia coli M12  CO715_20805  ATI07948.1  186 aa hypothetical protein 2.5e-13 ●●○○○ -1.22 -1.2152725217709
Escherichia coli M12  CO715_21460  ATI08068.1  293 aa LysR family transcriptional regulator 1.2e-82 ●●○○○ -1.21 -1.2148552297424
Escherichia coli M12  CO715_21350  ATI08047.1  364 aa ABC transporter permease 4.3e-9 ●●○○○ -1.21 -1.21464658372815
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3947  WP_001252662.1  E8XGX1  932 aa transcriptional regulator DagR 0.005 ●●○○○ -1.21 -1.2144106184195
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0866  WP_000210950.1  E8XBV3  421 aa DUF1479 domain-containing protein 1.0e-7 ●●○○○ -1.21 -1.21428230198337
Escherichia coli M12  CO715_08635  ATI05774.1  512 aa glutathione ABC transporter substrate-binding protein GsiB 5.7e-27 ●●○○○ -1.21 -1.21402064568541
Acinetobacter baumannii ATCC 17978  A1S_2780  ABO13192.2  285 aa rod shape-determining protein 1.1e-12 ●●○○○ -1.21 -1.21389877603274
Acinetobacter baumannii ATCC 17978  A1S_2862  ABO13268.2  A3M8M4  secA  907 aa preprotein translocase secretion protein of IISP family 2.5e-6 ●●○○○ -1.21 -1.21328322083051
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1030  AIK79653.1  308 aa phenylacetic acid degradation operon negative regulatory protein PaaX <1e-323 ●●○○○ -1.21 -1.21305107295786
Escherichia coli CFT073  c2627  AAN81083.1  A0A0H2VA83  yegV  321 aa Hypothetical sugar kinase yegV 0.01 ●●○○○ -1.21 -1.21274660566679
Escherichia coli M12  CO715_06880  ATI05463.1  50 aa isocitrate dehydrogenase 2.9e-14 ●●○○○ -1.21 -1.21214283155717
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1303  NP_230948.1  Q9KSF3  458 aa para-aminobenzoate synthase component I 1.2e-7 ●●○○○ -1.21 -1.21203398785915
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3133  AIK81705.1  204 aa putative elongation factor <1e-323 ●●○○○ -1.21 -1.21202313555184
Escherichia coli M12  CO715_03045  ATI04805.1  332 aa bile acid:sodium symporter 2.4e-9 ●●○○○ -1.21 -1.21193418554292
Escherichia coli M12  CO715_22545  ATI08262.1  134 aa hypothetical protein 2.5e-7 ●●○○○ -1.21 -1.21193418554292
Escherichia coli M12  CO715_03970  ATI04971.1  134 aa DUF2531 domain-containing protein 0.0037 ●●○○○ -1.21 -1.21193418554292
Porphyromonas gingivalis ATCC 33277  PGN_1940  WP_012458625.1  B2RM64  116 aa pyrophosphatase 1.6e-8 ●●○○○ -1.21 -1.21188755610159
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4263  CBW20349.1  A0A0H3NVR3  aspA  478 aa aspartate ammonia-lyase 0.021 ●●○○○ -1.21 -1.21187987711223
Escherichia coli M12  CO715_18655  ATI07560.1  328 aa MBL fold hydrolase 3.1e-50 ●●○○○ -1.21 -1.21130824750017
Escherichia coli CFT073  c2256  AAN80715.1  A0A0H2V9B4  ptrB  554 aa Protease II 0.024 ●●○○○ -1.21 -1.21116371986542
Escherichia coli M12  CO715_20755  ATI07938.1  408 aa multidrug resistance protein MdtG 0.00016 ●●○○○ -1.21 -1.21109960148592
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3229  AIK81790.1  334 aa N-acetyl-gamma-glutamyl-phosphate reductase <1e-323 ●●○○○ -1.21 -1.21090579248895
Escherichia coli M12  CO715_05295  ATI05195.1  142 aa universal stress protein UspC 7.2e-11 ●●○○○ -1.21 -1.21047366344318
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4109  AIK82655.1  107 aa rieske [2Fe-2S] domain protein 1.6e-14 ●●○○○ -1.21 -1.21007469077527
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1960  WP_000089042.1  E8XA75  otsA  473 aa alpha,alpha-trehalose-phosphate synthase 5.9e-7 ●●○○○ -1.21 -1.21004431319079
Escherichia coli M12  CO715_02750  ATI04751.1  287 aa neutral zinc metallopeptidase 6.4e-12 ●●○○○ -1.21 -1.20984772540043
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3259  AIK81820.1  224 aa hypothetical protein 3.6e-10 ●●○○○ -1.21 -1.20978386749333
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3872  WP_001112113.1  E8XG13  cysE  273 aa serine O-acetyltransferase 1.4e-7 ●●○○○ -1.21 -1.20916863899339
Escherichia coli M12  CO715_10305  ATI06056.1  101 aa hypothetical protein 1.5e-7 ●●○○○ -1.21 -1.20880449532919
Escherichia coli M12  CO715_00365  ATI04323.1  290 aa aldose 1-epimerase 0.0024 ●●○○○ -1.21 -1.20817855728644
Escherichia coli M12  CO715_10355  ATI06064.1  417 aa MFS transporter 9.4e-8 ●●○○○ -1.21 -1.20734397322944
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2614  WP_071822085.1  E8XGK2  shdA  2050 aa fibronectin-binding autotransporter adhesin ShdA 1.1e-7 ●●○○○ -1.21 -1.20662584613329
Escherichia coli M12  CO715_05080  ATI05160.1  388 aa serine-type D-Ala-D-Ala carboxypeptidase DacD 9.0e-48 ●●○○○ -1.21 -1.2063007431582
Acinetobacter baumannii ATCC 17978  A1S_0145  ABO10628.2  161 aa transcriptional repressor of Zn transport system (Fur family) 5.5e-7 ●●○○○ -1.21 -1.20527690999495
Escherichia coli M12  CO715_23760  ATI08458.1  227 aa DNA-binding response regulator 5.6e-26 ●●○○○ -1.21 -1.20525751308696
Escherichia coli M12  CO715_21735  ATI08118.1  181 aa hypothetical protein 1.5e-235 ●●○○○ -1.21 -1.20504886707271
Retrieved entries 3,501–3,600 out of 36,363 total in 790.1 ms (Link to these results)