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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2738  NP_232364.1  Q9KNK0  pckA  542 aa phosphoenolpyruvate carboxykinase 0.0097 ○○○○○ 0.05 0.0463294224479942
Escherichia coli M12  CO715_07415  ATI05557.1  209 aa protein Sxy 1.2e-14 ○○○○○ 0.05 0.0466185724062124
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3401  AIK81957.1  397 aa major Facilitator Superfamily protein <1e-323 ○○○○○ 0.05 0.0472271627705542
Escherichia coli M12  CO715_14600  ATI06833.1  140 aa 4-hydroxybenzoyl-CoA thioesterase 1.4e-5 ○○○○○ 0.05 0.0478704484917056
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0917  NP_233302.1  Q9KL32  161 aa TetR family transcriptional regulator 0.038 ○○○○○ 0.05 0.0478914492926611
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0675  NP_233063.1  Q9KLR7  583 aa nitrate/nitrite sensor protein NarQ 0.032 ○○○○○ 0.05 0.0479253908042109
Escherichia coli M12  CO715_21415  ATI08059.1  313 aa pseudouridine kinase 1.1e-82 ○○○○○ 0.05 0.0480790945059544
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3108  AIK81689.1  446 aa transporter, anaerobic C4-dicarboxylate uptake family protein <1e-323 ○○○○○ 0.05 0.04873610848914
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1497  NP_231138.1  Q9KRY6  proQ  208 aa solute/DNA competence effector 0.00089 ○○○○○ 0.05 0.0490224926087398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4036  AIK82583.1  289 aa bacterial regulatory helix-turn-helix, AraC family protein 4.4e-5 ○○○○○ 0.05 0.0493040998752339
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2266  AIK80871.1  195 aa putative fimbrillin MatB 1.3e-7 ○○○○○ 0.05 0.0495979640358373
Escherichia coli M12  CO715_14895  ATI06886.1  271 aa hypothetical protein 2.1e-15 ○○○○○ 0.05 0.0497482626199453
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2537  NP_232165.1  Q9KP42  thiQ  244 aa thiamine ABC transporter ATP-binding protein 0.021 ○○○○○ 0.05 0.0504819051328088
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2275  NP_231906.1  Q9KPT7  crl  129 aa DNA-binding transcriptional regulator Crl 0.011 ○○○○○ 0.05 0.0505119194711879
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2506  AIK81103.1  327 aa thiamin/thiamine pyrophosphate ABC transporter, thiamin/thiamine pyrophospate-binding protein <1e-323 ○○○○○ 0.05 0.0505597333207425
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4882  AIK83409.1  946 aa his Kinase A domain protein <1e-323 ○○○○○ 0.05 0.050613206656312
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2174  AIK80779.1  454 aa sugar (and other) transporter family protein 2.3e-11 ○○○○○ 0.05 0.0513961445998831
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2095  NP_231727.1  Q9KQA5  548 aa phosphoglucomutase 0.0013 ○○○○○ 0.05 0.0514918235386174
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2672  NP_232300.1  Q9KNQ9  rraA  171 aa ribonuclease activity regulator protein RraA 0.00016 ○○○○○ 0.05 0.0516066702617615
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1447  NP_231090.1  H9L4R8  467 aa RTX toxin transporter 0.0054 ○○○○○ 0.05 0.0518952291630676
Escherichia coli M12  CO715_01920  ATI04596.1  449 aa guanine/hypoxanthine permease GhxP 3.9e-49 ○○○○○ 0.05 0.0520433687766828
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4086  AIK82632.1  415 aa branched-chain amino acid transport system / permease component family protein <1e-323 ○○○○○ 0.05 0.0521115151567484
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2600  NP_232228.1  Q9KNY0  622 aa hypothetical protein 0.00021 ○○○○○ 0.05 0.0522093844459429
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1884  AIK80490.1  249 aa dsbGreduced 5.2e-11 ○○○○○ 0.05 0.0525366694372926
Escherichia coli M12  CO715_13185  ATI06576.1  375 aa cell division protein ZapE 0.00023 ○○○○○ 0.05 0.0528779528336783
Escherichia coli M12  CO715_11465  ATI06268.1  361 aa tartrate dehydrogenase 0.0079 ○○○○○ 0.05 0.0541298289191714
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1663  AIK80283.1  306 aa binding-protein-dependent transport system innermembrane component family protein 0.023 ○○○○○ 0.05 0.0544550852239994
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2468  AIK81065.1  130 aa 8-oxo-dGTPase 0.0043 ○○○○○ 0.05 0.05471840341651
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4989  AIK83515.1  345 aa binding-protein-dependent transport system innermembrane component family protein 7.9e-7 ○○○○○ 0.06 0.055287562659576
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0900  NP_230547.1  Q9KTK2  524 aa GGDEF family protein 0.0015 ○○○○○ 0.06 0.0553501395309508
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2073  NP_231705.1  Q9KQC7  198 aa hypothetical protein 0.00035 ○○○○○ 0.06 0.0554883846695746
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2610  AIK81204.1  348 aa diguanylate cyclase domain protein <1e-323 ○○○○○ 0.06 0.0563143575645278
Porphyromonas gingivalis ATCC 33277  PGN_0185  WP_012457311.1  B2RH59  fimE  550 aa hypothetical protein 0.012 ○○○○○ 0.06 0.0563348713882949
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2267  AIK80872.1  180 aa bacterial regulatory, luxR family protein 0.027 ○○○○○ 0.06 0.0564112894790428
Escherichia coli M12  CO715_18215  ATI07482.1  147 aa PTS mannitol transporter subunit IIA 0.00097 ○○○○○ 0.06 0.0564249350759089
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2053  NP_231685.1  Q9KQE7  ccmE  160 aa cytochrome c-type biogenesis protein CcmE 0.0035 ○○○○○ 0.06 0.057035100011137
Escherichia coli M12  CO715_23785  ATI08463.1  1047 aa CusA/CzcA family heavy metal efflux RND transporter 0.03 ○○○○○ 0.06 0.0572595191329043
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0755  NP_230404.2  Q9KTX5  pepB  429 aa aminopeptidase 0.015 ○○○○○ 0.06 0.0574326398405782
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3097  AIK81678.1  165 aa regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ family protein <1e-323 ○○○○○ 0.06 0.0581844516361079
Escherichia coli M12  CO715_17260  ATI07312.1  492 aa sugar kinase 0.027 ○○○○○ 0.06 0.0583027492041486
Escherichia coli M12  CO715_01820  ATI04579.1  683 aa multidrug transporter subunit MdtO 3.7e-27 ○○○○○ 0.06 0.0591373332611441
Escherichia coli M12  CO715_03720  ATI04927.1  153 aa GNAT family N-acetyltransferase 7.3e-6 ○○○○○ 0.06 0.0593459792753929
Escherichia coli M12  CO715_05390  ATI05211.1  248 aa copper homeostasis protein CutC 0.0042 ○○○○○ 0.06 0.0593459792753929
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0585  NP_232975.1  Q9KM04  203 aa glutathione S-transferase 0.028 ○○○○○ 0.06 0.0596017010660431
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4859  AIK83386.1  313 aa hypothetical protein 8.9e-16 ○○○○○ 0.06 0.0598197736977335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4940  AIK83466.1  231 aa lrgB-like family protein <1e-323 ○○○○○ 0.06 0.059926878910548
Escherichia coli CFT073  c1640  AAN80105.1  P0A3R7  nhaP2  578 aa Putative Na(+)/H(+) exchanger ycgO 1.7e-22 ○○○○○ 0.06 0.0600448507136023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3283  AIK81844.1  300 aa formate dehydrogenase, beta subunit <1e-323 ○○○○○ 0.06 0.0603791978766353
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4051  AIK82598.1  507 aa glycosyl hydrolases 43 family protein 1.1e-11 ○○○○○ 0.06 0.0606123706815887
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2037  AIK80643.1  334 aa D-fructose-responsive transcription factor family protein 1.8e-14 ○○○○○ 0.06 0.0606658267020712
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2644  AIK81238.1  479 aa D-aminoacylase 7.1e-9 ○○○○○ 0.06 0.0608267733889193
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1079  NP_230724.1  Q9KT26  329 aa hypothetical protein 0.0012 ○○○○○ 0.06 0.0615374990993744
Escherichia coli M12  CO715_15010  ATI06907.1  222 aa hypothetical protein 8.9e-15 ○○○○○ 0.06 0.0618497314463792
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3048  AIK81633.1  429 aa phage lambda receptor protein maltose high-affinity receptor 1.8e-15 ○○○○○ 0.06 0.0623491021758682
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1194  NP_230839.1  Q9KSR2  350 aa hypothetical protein 6.3e-5 ○○○○○ 0.06 0.0627455921928246
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0580  NP_232970.2  Q9KM09  161 aa hypothetical protein 0.0021 ○○○○○ 0.06 0.0627522589415248
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4444  AIK82987.1  730 aa hypothetical protein <1e-323 ○○○○○ 0.06 0.0629288869520637
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0617  NP_230266.1  Q9KUA6  327 aa peptide ABC transporter ATP-binding protein 0.00097 ○○○○○ 0.06 0.0631324041396528
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3105  AIK81686.1  510 aa diguanylate cyclase domain protein <1e-323 ○○○○○ 0.06 0.0632081994424866
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4374  AIK82917.1  455 aa L-serine ammonia-lyase 1.2e-11 ○○○○○ 0.06 0.0633796335589407
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0424  NP_232818.1  Q9KMD7  148 aa hypothetical protein 0.0063 ○○○○○ 0.06 0.0637192786889344
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2990  AIK81575.1  652 aa acetate--CoA ligase <1e-323 ○○○○○ 0.06 0.0637651002753862
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3664  AIK82219.1  162 aa acetyltransferase family protein 5.1e-9 ○○○○○ 0.06 0.0638300509822354
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2720  AIK81310.1  293 aa hypothetical protein 3.7e-9 ○○○○○ 0.07 0.0650386281256348
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1328  NP_230972.1  Q9KSD0  337 aa beta-methylgalactoside transporter inner membrane protein 0.00073 ○○○○○ 0.07 0.0651740355643498
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4679  AIK83213.1  410 aa major Facilitator Superfamily protein 8.5e-8 ○○○○○ 0.07 0.0652872248879749
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0200  NP_229857.1  Q9KVE6  718 aa iron(III) compound receptor 0.0023 ○○○○○ 0.07 0.0655311936337268
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0945  NP_233329.1  Q9KL05  406 aa maltose ABC transporter substrate-binding protein 0.033 ○○○○○ 0.07 0.0659285595918869
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3913  AIK82461.1  331 aa putative peptidase 2.6e-15 ○○○○○ 0.07 0.0664990615289218
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0321  NP_229975.1  Q9KV37  tufA  394 aa elongation factor Tu 0.00012 ○○○○○ 0.07 0.0667010602961167
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1721  AIK80341.1  329 aa molybdenum cofactor biosynthesis protein A 0.00021 ○○○○○ 0.07 0.0667116718094696
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4193  AIK82738.1  212 aa ureE urease accessory, N-terminal domain protein <1e-323 ○○○○○ 0.07 0.0669822943510291
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1055  NP_233437.1  Q9KKP7  307 aa LysR family transcriptional regulator 0.0045 ○○○○○ 0.07 0.067057325619076
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1043  NP_233425.1  Q9KKQ9  314 aa TagE protein 0.027 ○○○○○ 0.07 0.0673633653337607
Escherichia coli M12  CO715_20365  ATI07870.1  257 aa YaiO family outer membrane beta-barrel protein 5.6e-5 ○○○○○ 0.07 0.0674831738310985
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2381  NP_232011.1  Q9KPI6  btuF  276 aa hypothetical protein 0.0014 ○○○○○ 0.07 0.0678829386350136
Escherichia coli M12  CO715_22010  ATI08170.1  321 aa GDP-L-fucose synthase 0.019 ○○○○○ 0.07 0.0679004658595963
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2638  AIK81232.1  177 aa acetyltransferase family protein <1e-323 ○○○○○ 0.07 0.0685241609837789
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3537  AIK82093.1  393 aa xylH 3.2e-15 ○○○○○ 0.07 0.0686212300273914
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0780  NP_233166.1  Q9KLG4  388 aa UDP-glucose 6-dehydrogenase 0.0029 ○○○○○ 0.07 0.0690215877271943
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3629  AIK82185.1  349 aa hypothetical protein 1.0e-13 ○○○○○ 0.07 0.0691020904285694
Escherichia coli M12  CO715_01135  ATI04459.1  483 aa protein viaA 6.4e-8 ○○○○○ 0.07 0.0691523419450894
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1656  NP_231293.1  Q9KRI5  287 aa hypothetical protein 0.0088 ○○○○○ 0.07 0.0691775460402483
Escherichia coli M12  CO715_08890  ATI05820.1  234 aa hypothetical protein 0.016 ○○○○○ 0.07 0.0695696339735872
Escherichia coli M12  CO715_21750  ATI08121.1  344 aa adhesin 2.2e-31 ○○○○○ 0.07 0.069778279987836
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2150  NP_231781.1  Q9KQ54  131 aa hypothetical protein 0.012 ○○○○○ 0.07 0.0701715214061532
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1094  NP_230739.1  Q9KT11  324 aa oligopeptide ABC transporter ATP-binding protein 0.00034 ○○○○○ 0.07 0.0702484368098864
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0687  NP_233075.1  Q9KLQ5  fbpC  351 aa ferric transporter ATP-binding subunit 0.0021 ○○○○○ 0.07 0.0702502536723097
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1413  NP_231056.1  Q9KS47  578 aa methyl-accepting chemotaxis protein 0.0019 ○○○○○ 0.07 0.0705448596248435
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1964  NP_231598.1  Q9KQN4  291 aa hypothetical protein 3.9e-5 ○○○○○ 0.07 0.0708850609463944
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2815  AIK81404.1  435 aa 6-phospho-beta-glucosidase <1e-323 ○○○○○ 0.07 0.071008370227083
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2071  AIK80676.1  358 aa tRNA 2-selenouridine synthase 2.9e-5 ○○○○○ 0.07 0.0713050108200305
Porphyromonas gingivalis ATCC 33277  PGN_0336  WP_004583881.1  B2RHL0  207 aa hypothetical protein 5.2e-5 ○○○○○ 0.07 0.0713439245139355
Porphyromonas gingivalis ATCC 33277  PGN_0336  WP_077084031.1  B2RHL0  62 aa hypothetical protein 5.2e-5 ○○○○○ 0.07 0.0713439245139355
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0458  NP_230112.1  Q9KUQ7  96 aa hypothetical protein 0.018 ○○○○○ 0.07 0.0714508515267873
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1883  AIK80489.1  187 aa peroxiredoxin 3.1e-11 ○○○○○ 0.07 0.0729668003563072
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4865  AIK83392.1  267 aa 2-keto-3-deoxy-L-rhamnonate aldolase <1e-323 ○○○○○ 0.07 0.0735208264599144
Escherichia coli M12  CO715_23265  ATI08386.1  97 aa DNA repair protein RadC 0.014 ○○○○○ 0.07 0.0737425542585644
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5127  AIK83653.1  420 aa CP4-like integrase 6.3e-10 ○○○○○ 0.07 0.0738474222779587
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2642  AIK81236.1  495 aa sodium:solute symporter family protein <1e-323 ○○○○○ 0.07 0.0741721179504428
Retrieved entries 31,801–31,900 out of 36,363 total in 8.1 ms (Link to these results)