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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2232  NP_231863.1  Q9KPY0  419 aa hypothetical protein 0.0031 ○○○○○ 0.47 0.472102651504517
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4778  AIK83306.1  404 aa putative aminotransferase 1.7e-13 ○○○○○ 0.47 0.472720895337458
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4341  AIK82886.1  274 aa cobalt ABC transporter, ATP-binding family protein 0.00027 ○○○○○ 0.47 0.472788468527379
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2353  AIK80950.1  343 aa D-methionine ABC transporter, ATP-binding protein <1e-323 ○○○○○ 0.47 0.472870908492116
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4776  AIK83304.1  565 aa histidine kinase-, DNA gyrase B-, and HSP90-likeATPase family protein <1e-323 ○○○○○ 0.47 0.473019799909961
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1015  NP_230661.1  Q9KT88  rnfC  801 aa electron transport complex protein RnfC 0.0028 ○○○○○ 0.47 0.473225578200796
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0635  NP_230284.1  Q9KU88  98 aa hypothetical protein 0.00052 ○○○○○ 0.47 0.473805274103464
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5119  AIK83645.1  366 aa thiazolinyl imide reductase family protein 4.5e-12 ○○○○○ 0.47 0.474076081511727
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1967  AIK80572.1  487 aa bacterial regulatory, gntR family protein 7.2e-5 ○○○○○ 0.48 0.475832530241797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2395  AIK80992.1  472 aa H(+)/Cl(-) exchange transporter ClcA <1e-323 ○○○○○ 0.48 0.476870632503053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1404  AIK80027.1  517 aa periplasmic glucan biosynthesis, MdoG family protein 0.011 ○○○○○ 0.48 0.477698153306477
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1460  AIK80082.1  313 aa putative DNA-binding transcriptional regulator 4.7e-7 ○○○○○ 0.48 0.477848867406081
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3180  AIK81748.1  246 aa glycosyltransferase, WecB/TagA/CpsF family protein <1e-323 ○○○○○ 0.48 0.480756921454764
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4132  AIK82678.1  297 aa argP transcriptional activator 1.5e-11 ○○○○○ 0.48 0.481307330227719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4971  AIK83497.1  658 aa bacterially-derived sulfatase <1e-323 ○○○○○ 0.48 0.481548031326485
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4997  AIK83523.1  471 aa major Facilitator Superfamily protein 0.00019 ○○○○○ 0.48 0.483145391495321
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1984  AIK80590.1  366 aa metallo-beta-lactamase superfamily protein <1e-323 ○○○○○ 0.48 0.48355013157014
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4075  AIK82622.1  287 aa phage integrase family protein 2.8e-9 ○○○○○ 0.48 0.483981721196926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1745  AIK80365.1  321 aa acyltransferase family protein 0.0026 ○○○○○ 0.48 0.484406101939419
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1602  NP_231242.1  Q9KRN4  328 aa chemotaxis protein CheV 0.04 ○○○○○ 0.49 0.485418259208145
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4583  AIK83121.1  300 aa 23S rRNA pseudouridine synthase 5.6e-5 ○○○○○ 0.49 0.486535307025795
Porphyromonas gingivalis ATCC 33277  PGN_0236  WP_039417038.1  B2RHB0  191 aa membrane protein 3.4e-5 ○○○○○ 0.49 0.486715913668049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1956  AIK80562.1  350 aa binding-protein-dependent transport system innermembrane component family protein <1e-323 ○○○○○ 0.49 0.486893179750399
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3559  AIK82115.1  220 aa glycine zipper family protein <1e-323 ○○○○○ 0.49 0.488007358790147
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0416  NP_232810.1  Q9KME4  107 aa hypothetical protein 0.0011 ○○○○○ 0.49 0.488986577480674
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4338  AIK82883.1  245 aa cobalamin biosynthesis protein CbiM 1.6e-14 ○○○○○ 0.49 0.489661326747059
Escherichia coli M12  CO715_06275  ATI05360.1  561 aa multidrug ABC transporter ATP-binding protein 0.022 ○○○○○ 0.49 0.49040864471354
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1944  AIK80550.1  463 aa L-fucose isomerase, C-terminal domain protein 9.7e-8 ○○○○○ 0.49 0.490651994334141
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1012  NP_233396.1  Q9KKT8  155 aa hypothetical protein 0.012 ○○○○○ 0.49 0.491198965676413
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3064  AIK81650.1  291 aa 23S rRNA pseudouridine 2604 synthase <1e-323 ○○○○○ 0.49 0.493658951803706
Porphyromonas gingivalis ATCC 33277  PGN_1984  WP_005874429.1  B2RMA7  73 aa hypothetical protein 5.2e-12 ○○○○○ 0.49 0.494491648398595
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4476  AIK83019.1  259 aa short chain dehydrogenase family protein <1e-323 ○○○○○ 0.49 0.494710593474306
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4465  AIK83008.1  337 aa ascG transcriptional repressor 0.0024 ○○○○○ 0.5 0.496658555108864
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3563  AIK82119.1  193 aa putative lipase 2.4e-12 ○○○○○ 0.5 0.499329849882201
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3844  AIK82394.1  455 aa peptidase Do family protein 0.0098 ○○○○○ 0.5 0.499627116396408
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2853  AIK81442.1  290 aa araC <1e-323 ○○○○○ 0.5 0.499788552717665
Escherichia coli M12  CO715_03380  ATI04861.1  879 aa outer membrane usher protein 0.019 ○○○○○ 0.5 0.500840945425983
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4412  AIK82955.1  378 aa nlpD putative outer membrane lipoprotein <1e-323 ○○○○○ 0.5 0.501530206689099
Escherichia coli CFT073  c2348  AAN80807.1  A0A0H2V859  342 aa Outer membrane porin protein nmpC precursor 0.0067 ○○○○○ 0.5 0.501778480478839
Escherichia coli M12  CO715_01435  ATI04509.1  500 aa glutamate/gamma-aminobutyrate family transporter YjeM 0.03 ○○○○○ 0.5 0.502092821511477
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3836  AIK82386.1  422 aa na+ symporter family protein 1.1e-16 ○○○○○ 0.5 0.50414707454169
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2123  AIK80728.1  410 aa cyclodextrin-binding protein <1e-323 ○○○○○ 0.5 0.504792451342111
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2693  AIK81287.1  374 aa ABC-2 type transporter family protein <1e-323 ○○○○○ 0.5 0.504848598446198
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3569  AIK82124.1  339 aa dppB <1e-323 ○○○○○ 0.5 0.504904337378093
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4630  AIK83164.1  277 aa aldose 1-epimerase family protein 3.1e-6 ○○○○○ 0.51 0.505214208998956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1525  AIK80145.1  153 aa asnC family protein <1e-323 ○○○○○ 0.51 0.505222662949523
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4869  AIK83396.1  448 aa glycerol-3-phosphate transporter <1e-323 ○○○○○ 0.51 0.505975539477767
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1960  AIK80566.1  445 aa aminotransferase class-III family protein <1e-323 ○○○○○ 0.51 0.506842840572243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4660  AIK83194.1  230 aa hypothetical protein 0.018 ○○○○○ 0.51 0.506969393950707
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1252  NP_230897.1  Q9KSK4  415 aa competence damage protein CinA 0.0017 ○○○○○ 0.51 0.507832475105005
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5077  AIK83603.1  464 aa thiF family protein 1.6e-6 ○○○○○ 0.51 0.508141968417703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4844  AIK83371.1  180 aa nuoI 5.0e-7 ○○○○○ 0.51 0.5083139797159
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1643  AIK80263.1  134 aa phage regulatory CII family protein 7.7e-7 ○○○○○ 0.51 0.509387642170855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4040  AIK82587.1  727 aa radical SAM superfamily protein <1e-323 ○○○○○ 0.51 0.511326564283235
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2407  AIK81004.1  275 aa type II secretion system protein C 4.3e-15 ○○○○○ 0.51 0.511538947910641
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3719  AIK82274.1  56 aa hypothetical protein 0.026 ○○○○○ 0.51 0.512359303715391
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2576  AIK81173.1  452 aa inner membrane CreD family protein <1e-323 ○○○○○ 0.51 0.513043253173444
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4705  AIK83239.1  67 aa hypothetical protein 0.02 ○○○○○ 0.51 0.514770061645385
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0319  NP_232715.1  Q9K2J6  90 aa hypothetical protein 0.022 ○○○○○ 0.52 0.516327612257507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4332  AIK82877.1  257 aa precorrin-4 C11-methyltransferase <1e-323 ○○○○○ 0.52 0.517190545689039
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0792  NP_233178.1  Q9K344  114 aa transposase OrfAB subunit A 0.033 ○○○○○ 0.52 0.517233623734278
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0654  NP_230303.1  Q9KU69  175 aa hypothetical protein 0.00023 ○○○○○ 0.52 0.5173254296963
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1779  NP_231414.1  Q9KR64  siaP  321 aa C4-dicarboxylate-binding protein 0.028 ○○○○○ 0.52 0.517345495843172
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2357  NP_231987.1  Q9KPL0  77 aa hypothetical protein 0.0044 ○○○○○ 0.52 0.517488569506708
Porphyromonas gingivalis ATCC 33277  PGN_0384  WP_012457467.1  B2RHQ8  145 aa DUF695 domain-containing protein 3.3e-6 ○○○○○ 0.52 0.518181402816295
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1647  NP_231284.2  Q9KRJ3  587 aa hypothetical protein 0.028 ○○○○○ 0.52 0.519391536345838
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1991  AIK80597.1  95 aa helix-turn-helix family protein 0.014 ○○○○○ 0.52 0.519421408014557
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4969  AIK83495.1  603 aa adenine deaminase 2 5.8e-9 ○○○○○ 0.52 0.519878524982759
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4954  AIK83480.1  755 aa &beta-D-glucoside glucohydrolase, periplasmic <1e-323 ○○○○○ 0.52 0.520391536474176
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4063  AIK82610.1  200 aa hypothetical protein 0.0036 ○○○○○ 0.52 0.521187594328943
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2303  NP_231934.1  Q9KPR3  193 aa hypothetical protein 0.011 ○○○○○ 0.52 0.521247009854749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2354  AIK80951.1  213 aa binding-protein-dependent transport system innermembrane component family protein 3.0e-15 ○○○○○ 0.52 0.52320032225303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1461  AIK80081.1  426 aa FAD binding domain protein 0.028 ○○○○○ 0.53 0.525285815159638
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2802  AIK81391.1  488 aa C4-dicarboxylate anaerobic carrier family protein <1e-323 ○○○○○ 0.53 0.526031867988756
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4939  AIK83465.1  286 aa cytidine deaminase 0.0066 ○○○○○ 0.53 0.526365835000158
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0300  NP_229955.1  Q9KV57  607 aa hypothetical protein 0.03 ○○○○○ 0.53 0.52655283935257
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4054  AIK82601.1  95 aa hypothetical protein 5.4e-7 ○○○○○ 0.53 0.526975910455921
Porphyromonas gingivalis ATCC 33277  PGN_0020  WP_012457175.1  B2RGP4  rex  218 aa redox-sensing transcriptional repressor Rex <1e-323 ○○○○○ 0.53 0.527157780562024
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1653  NP_231290.2  Q9KRI8  1176 aa sensory box sensor histidine kinase/response regulator VieS 0.032 ○○○○○ 0.53 0.528111900010637
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2056  AIK80662.1  290 aa acetyltransferase family protein <1e-323 ○○○○○ 0.53 0.52843744361963
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2080  AIK80685.1  225 aa putative transporter subunit: ATP-binding component of ABC superfamily <1e-323 ○○○○○ 0.53 0.528890294774354
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1953  AIK80559.1  554 aa choline dehydrogenase 6.8e-9 ○○○○○ 0.53 0.529071501297107
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3148  AIK81720.1  482 aa recombination limiting protein <1e-323 ○○○○○ 0.53 0.529577627960463
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3485  AIK82041.1  238 aa ribonuclease PH 0.00016 ○○○○○ 0.53 0.530474053580651
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0920  NP_230567.1  Q9KTI2  382 aa exopolysaccharide biosynthesis protein EpsF 0.0017 ○○○○○ 0.53 0.530786882024428
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1815  AIK80428.1  682 aa K+-transporting ATPase, B subunit 9.4e-6 ○○○○○ 0.53 0.531067349670032
Porphyromonas gingivalis ATCC 33277  PGN_0660  WP_004585168.1  B2RII4  188 aa peroxiredoxin 3.7e-13 ○○○○○ 0.53 0.531825440723003
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4729  AIK83263.1  206 aa putative carboxysome structural protein with predicted role in ethanolamine utilization <1e-323 ○○○○○ 0.53 0.532336125342571
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0778  NP_230427.1  H9L4Q0  358 aa ferric vibriobactin ABC transporter permease 0.01 ○○○○○ 0.53 0.532752650114615
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4279  AIK82824.1  719 aa hypothetical protein <1e-323 ○○○○○ 0.53 0.533387044595211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4528  AIK83066.1  506 aa aldehyde dehydrogenase family protein <1e-323 ○○○○○ 0.53 0.533584392149985
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2747  NP_232373.1  Q9KNJ1  196 aa hypothetical protein 0.006 ○○○○○ 0.53 0.534149685900678
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2159  AIK80764.1  491 aa ampG muropeptide MFS transporter 3.9e-13 ○○○○○ 0.54 0.535674165188903
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1835  AIK80448.1  250 aa HAD hydrolase, IA, variant 1 family protein 2.4e-10 ○○○○○ 0.54 0.537399529049705
Porphyromonas gingivalis ATCC 33277  PGN_1463  WP_012458289.1  B2RKT7  286 aa decaprenyl-phosphate phosphoribosyltransferase <1e-323 ○○○○○ 0.54 0.537607440879459
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1680  AIK80300.1  441 aa glycosyl hydrolase 1 family protein <1e-323 ○○○○○ 0.54 0.538328468255622
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2625  AIK81219.1  308 aa hypothetical protein <1e-323 ○○○○○ 0.54 0.539258911487433
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0603  NP_230253.1  Q9KUB9  764 aa hypothetical protein 2.0e-6 ○○○○○ 0.54 0.539463887734102
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1827  NP_231461.1  Q9KR20  388 aa mannose-6-phosphate isomerase 2.9e-5 ○○○○○ 0.54 0.540093793891277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2098  AIK80703.1  183 aa adenine phosphoribosyltransferase 0.037 ○○○○○ 0.54 0.540659671433501
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