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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_10240  ATI06044.1  62 aa cell division inhibition protein DicB 1.2e-10 ●○○○○ -0.6 -0.600392717779506
Escherichia coli M12  CO715_08810  ATI05806.1  361 aa malate/lactate/ureidoglycolate dehydrogenase 6.3e-5 ●○○○○ -0.6 -0.600392717779506
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0724  NP_230373.1  Q9KU06  731 aa phosphate ABC transporter permease 0.00061 ●○○○○ -0.6 -0.600228441130862
Porphyromonas gingivalis ATCC 33277  PGN_0361  WP_004583909.1  B2RHN5  355 aa glycosyltransferase family 2 protein <1e-323 ●○○○○ -0.6 -0.599937752997956
Porphyromonas gingivalis ATCC 33277  PGN_0361  WP_080504395.1  B2RHN5  65 aa hypothetical protein <1e-323 ●○○○○ -0.6 -0.599937752997956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2665  AIK81259.1  318 aa cobalamin synthesis cobW C-terminal domain protein 8.9e-6 ●○○○○ -0.6 -0.599412896049198
Acinetobacter baumannii ATCC 17978  A1S_2600  ABO13017.2  129 aa hypothetical protein 0.034 ●○○○○ -0.6 -0.599034965054723
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0495  NP_230149.1  Q9KUM0  224 aa hypothetical protein 6.1e-10 ●○○○○ -0.6 -0.598690221140952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3173  AIK81745.1  393 aa hypothetical protein 3.3e-5 ●○○○○ -0.6 -0.598395900448091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1397  AIK80019.1  37 aa hypothetical protein 0.032 ●○○○○ -0.6 -0.59835014109238
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3448  AIK82004.1  464 aa sugar (Glycoside-Pentoside-Hexuronide) transporter domain protein <1e-323 ●○○○○ -0.6 -0.598250921469729
Porphyromonas gingivalis ATCC 33277  PGN_1729  WP_043876334.1  B2RLK3  339 aa GNAT family N-acetyltransferase 0.01 ●○○○○ -0.6 -0.59759901871906
Escherichia coli M12  CO715_21095  ATI08003.1  267 aa 2-keto-3-deoxy-L-rhamnonate aldolase 0.029 ●○○○○ -0.6 -0.597471673580022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1389  AIK80012.1  402 aa major Facilitator Superfamily protein 9.5e-15 ●○○○○ -0.6 -0.597316433120641
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3679  AIK82234.1  502 aa glpD 3.6e-14 ●○○○○ -0.6 -0.597286962138208
Acinetobacter baumannii ATCC 17978  A1S_1979  ABO12406.2  217 aa putative transcriptional regulator 0.00018 ●○○○○ -0.6 -0.597127541386115
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3276  AIK81837.1  182 aa helix-turn-helix family protein 2.2e-13 ●○○○○ -0.6 -0.597081025608672
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3230  AIK81791.1  383 aa acetylornithine deacetylase <1e-323 ●○○○○ -0.6 -0.596407820267917
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4549  AIK83087.1  303 aa bacterial regulatory helix-turn-helix, lysR family protein 2.2e-13 ●○○○○ -0.6 -0.595706993878796
Escherichia coli M12  CO715_06195  ATI05345.1  190 aa flavodoxin family protein 3.7e-8 ●○○○○ -0.6 -0.595385213437534
Escherichia coli M12  CO715_07660  ATI05603.1  193 aa D-alanyl-D-alanine dipeptidase 0.028 ●○○○○ -0.6 -0.595385213437534
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4647  AIK83181.1  258 aa sseB family protein 3.4e-7 ●○○○○ -0.59 -0.594998314892284
Escherichia coli M12  CO715_24135  ATI08528.1  122 aa hypothetical protein 5.1e-6 ●○○○○ -0.59 -0.594550629380538
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4180  AIK82725.1  141 aa type VII secretion system (T7SS), usher family protein 0.0034 ●○○○○ -0.59 -0.594106497442043
Escherichia coli M12  CO715_04735  ATI05103.1  457 aa flagellum-specific ATP synthase FliL 0.0014 ●○○○○ -0.59 -0.593924691337792
Porphyromonas gingivalis ATCC 33277  PGN_0555  WP_004585352.1  B2RI79  225 aa hypothetical protein 0.0016 ●○○○○ -0.59 -0.593386112795414
Escherichia coli M12  CO715_18845  ATI07592.1  189 aa flavin reductase family protein 2.0e-25 ●○○○○ -0.59 -0.593090107280796
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0212  NP_229869.1  Q9KVD4  lpxM  325 aa lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 7.2e-5 ●○○○○ -0.59 -0.5925695704446
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4842  AIK83369.1  841 aa NADH dehydrogenase (quinone), G subunit 0.0019 ●○○○○ -0.59 -0.59209042232381
Escherichia coli M12  CO715_06820  ATI05452.1  327 aa porin 1.1e-53 ●○○○○ -0.59 -0.591838231195303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5123  AIK83649.1  570 aa ABC transporter family protein 5.5e-12 ●○○○○ -0.59 -0.59143041810895
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2117  AIK80722.1  423 aa lamB porin family protein 1.3e-9 ●○○○○ -0.59 -0.591166932624471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4841  AIK83368.1  445 aa NADH oxidoreductase (quinone), F subunit 0.00088 ●○○○○ -0.59 -0.590898368582638
Porphyromonas gingivalis ATCC 33277  PGN_1539  WP_052269036.1  B2RL13  457 aa TolC family protein <1e-323 ●○○○○ -0.59 -0.590808691131695
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2809  AIK81398.1  128 aa hypothetical protein 0.0015 ●○○○○ -0.59 -0.590455307722924
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2937  WP_000492669.1  E8XK43  alaE  149 aa L-alanine exporter AlaE 0.014 ●○○○○ -0.59 -0.590161584478576
Acinetobacter baumannii ATCC 17978  A1S_1230  ABO11659.1  276 aa phage putative head morphogenesis protein 0.00027 ●○○○○ -0.59 -0.589725734591976
Porphyromonas gingivalis ATCC 33277  PGN_1175  WP_012458081.1  B2RJZ9  256 aa enoyl-CoA hydratase <1e-323 ●○○○○ -0.59 -0.58935315750503
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0519  NP_232910.1  Q9KM69  326 aa DNA-binding transcriptional regulator FruR 0.017 ●○○○○ -0.59 -0.589315626944847
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0768  NP_233154.1  Q9KLH6  422 aa DEAD/DEAH box helicase 8.5e-5 ●○○○○ -0.59 -0.589226750854334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1934  AIK80540.1  742 aa tonB-dependent siderophore receptor family protein <1e-323 ●○○○○ -0.59 -0.589196920758122
Porphyromonas gingivalis ATCC 33277  PGN_0002  WP_004583405.1  B2RGM6  190 aa N-acetyltransferase <1e-323 ●○○○○ -0.59 -0.588844753552965
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0139  NP_229797.1  Q9KVK4  156 aa DPS family protein 0.002 ●○○○○ -0.59 -0.58870295207977
Porphyromonas gingivalis ATCC 33277  PGN_0317  WP_012457421.1  B2RHJ1  413 aa bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase <1e-323 ●○○○○ -0.59 -0.588602857923832
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2244  WP_001197952.1  E8XCZ7  176 aa DUF1307 domain-containing protein 0.0044 ●○○○○ -0.59 -0.588255871340492
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1410  NP_231053.1  Q9KS50  406 aa multidrug resistance protein VceA 3.5e-5 ●○○○○ -0.59 -0.587331976600632
Acinetobacter baumannii ATCC 17978  A1S_2991  ABO13394.1  444 aa GTP-binding protein 0.00011 ●○○○○ -0.59 -0.587280822543401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0599  NP_232988.1  Q9KLZ2  301 aa hypothetical protein 1.3e-6 ●○○○○ -0.59 -0.587091540210956
Acinetobacter baumannii ATCC 17978  A1S_2925  ABO13330.1  109 aa hypothetical protein 0.001 ●○○○○ -0.59 -0.586587625334672
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4356  AIK82899.1  140 aa L-fucose mutarotase 1.1e-8 ●○○○○ -0.59 -0.586386445170929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5157  AIK83678.1  172 aa hypothetical protein 0.0083 ●○○○○ -0.59 -0.586323833217618
Escherichia coli M12  CO715_11350  ATI06247.1  331 aa aldehyde dehydrogenase 7.0e-27 ●○○○○ -0.59 -0.586204788810584
Porphyromonas gingivalis ATCC 33277  PGN_1035  WP_012457974.1  B2RJK9  433 aa serine dehydratase subunit alpha family protein <1e-323 ●○○○○ -0.59 -0.586168132891437
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1958  AIK80564.1  278 aa ABC transporter family protein 0.028 ●○○○○ -0.59 -0.586143590519424
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1626  AIK80246.1  96 aa phage holin 2 family protein 0.007 ●○○○○ -0.59 -0.585989414270586
Acinetobacter baumannii ATCC 17978  A1S_1263  ABO11691.1  148 aa L-2-haloalkanoic acid dehalogenase 0.00018 ●○○○○ -0.59 -0.585650260558156
Escherichia coli M12  CO715_03250  ATI08714.1  331 aa transcriptional regulator 3.7e-10 ●○○○○ -0.59 -0.585578850767837
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0948  NP_230595.1  Q9KTF4  rlpA  263 aa rare lipoprotein A 0.004 ●○○○○ -0.59 -0.585111388048866
Acinetobacter baumannii ATCC 17978  A1S_3136  ABO13533.1  425 aa hypothetical protein 0.0036 ●○○○○ -0.58 -0.584393962570602
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4191  WP_014343927.1  E8XJJ5  341 aa hypothetical protein 0.028 ●○○○○ -0.58 -0.583236875269891
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3668  AIK82223.1  331 aa periplasmic binding and sugar binding domain of LacI family protein <1e-323 ●○○○○ -0.58 -0.583029708057208
Porphyromonas gingivalis ATCC 33277  PGN_1734  WP_043876335.1  B2RLK8  411 aa MFS transporter <1e-323 ●○○○○ -0.58 -0.582991309935343
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4124  AIK82670.1  231 aa putative peptidase 8.6e-5 ●○○○○ -0.58 -0.581962894815519
Escherichia coli M12  CO715_01935  ATI04599.1  154 aa redox-sensitive transcriptional activator SoxR 6.7e-7 ●○○○○ -0.58 -0.581823222511358
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3856  WP_000766684.1  E8XFZ8  yibf  202 aa glutathione S-transferase 0.043 ●○○○○ -0.58 -0.581697164242555
Escherichia coli M12  CO715_09920  ATI05998.1  391 aa isochorismate synthase EntC 0.0012 ●○○○○ -0.58 -0.581197284468611
Acinetobacter baumannii ATCC 17978  A1S_1171  ABO11601.2  180 aa hypothetical protein 0.031 ●○○○○ -0.58 -0.581132665938882
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0062  WP_000691461.1  E8XG81  citD2  97 aa citrate lyase acyl carrier protein 0.0065 ●○○○○ -0.58 -0.580850681764336
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3702  WP_001197669.1  E8XEN8  glgA  477 aa glycogen synthase GlgA 0.0054 ●○○○○ -0.58 -0.580750483623849
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0866  NP_230513.1  Q9KTN5  mltF  530 aa transglycosylase 0.00023 ●○○○○ -0.58 -0.580700224099925
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4542  AIK83080.1  310 aa NAD binding domain of 6-phosphogluconate dehydrogenase family protein 4.5e-9 ●○○○○ -0.58 -0.580352964914196
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3227  AIK81788.1  457 aa argininosuccinate lyase 1.5e-11 ●○○○○ -0.58 -0.580202873951361
Porphyromonas gingivalis ATCC 33277  PGN_0009  WP_012457166.1  B2RGN3  1003 aa glycosyl hydrolase 3.3e-11 ●○○○○ -0.58 -0.580104452391727
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1866  NP_231500.2  Q9KQY1  758 aa formate acetyltransferase 9.9e-8 ●○○○○ -0.58 -0.579792178543369
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3315  AIK81871.1  465 aa H+ antiporter-2 family protein <1e-323 ●○○○○ -0.58 -0.579307421784404
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3100  AIK81681.1  251 aa thiazole biosynthesis adenylyltransferase ThiF 3.2e-15 ●○○○○ -0.58 -0.579254806827789
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4555  AIK83093.1  294 aa bacterial regulatory helix-turn-helix, lysR family protein 2.1e-15 ●○○○○ -0.58 -0.578906215387083
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2656  NP_232284.1  Q9KNS5  602 aa fumarate reductase flavoprotein subunit 3.8e-7 ●○○○○ -0.58 -0.578493519041788
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0005  WP_000906175.1  E8XG25  yaaa  257 aa peroxide stress protein YaaA 0.0088 ●○○○○ -0.58 -0.578319445214755
Porphyromonas gingivalis ATCC 33277  PGN_0302  WP_039417064.1  B2RHH6  82 aa hypothetical protein <1e-323 ●○○○○ -0.58 -0.578137462310958
Porphyromonas gingivalis ATCC 33277  PGN_0302  WP_012457408.1  B2RHH6  192 aa rubrerythrin family protein <1e-323 ●○○○○ -0.58 -0.578137462310958
Porphyromonas gingivalis ATCC 33277  PGN_0431  WP_077111014.1  B2RHV5  464 aa hypothetical protein <1e-323 ●○○○○ -0.58 -0.578081024637521
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3945  AIK82493.1  194 aa conserved inner membrane protein <1e-323 ●○○○○ -0.58 -0.577728391239731
Escherichia coli M12  CO715_08860  ATI05814.1  368 aa inner membrane transport permease YbhR 4.7e-6 ●○○○○ -0.58 -0.57765030222638
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0984  NP_233368.1  Q9KKW6  lldD  378 aa L-lactate dehydrogenase 0.039 ●○○○○ -0.58 -0.577247268441679
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3752  WP_001214750.1  E8XF97  yhhJ  374 aa ABC transporter permease 0.017 ●○○○○ -0.58 -0.576690688849911
Porphyromonas gingivalis ATCC 33277  PGN_0183  WP_039417483.1  B2RH57  fimC  453 aa DUF4906 domain-containing protein 2.8e-6 ●○○○○ -0.58 -0.576537119107081
Porphyromonas gingivalis ATCC 33277  PGN_1327  WP_012458187.1  B2RKF1  336 aa hypothetical protein 0.023 ●○○○○ -0.58 -0.576537119107081
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1407  NP_231050.1  Q9KS53  397 aa ATP-dependent RNA helicase RhlE 0.0022 ●○○○○ -0.58 -0.5760640898872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2847  AIK81436.1  1258 aa hypothetical protein <1e-323 ●○○○○ -0.58 -0.575956219011712
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3248  AIK81809.1  331 aa cytR transcriptional dual regulator <1e-323 ●○○○○ -0.58 -0.575460708868692
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3021  AIK81606.1  116 aa bacterial regulatory helix-turn-helix, AraC family protein 0.0031 ●○○○○ -0.57 -0.574775976466691
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2818  AIK81407.1  707 aa anaerobic ribonucleoside-triphosphate reductase <1e-323 ●○○○○ -0.57 -0.574726135475654
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3968  AIK82516.1  184 aa transcriptional regulator PadR-like family protein 0.035 ●○○○○ -0.57 -0.574512438422226
Escherichia coli M12  CO715_13125  ATI06566.1  496 aa MFS transporter 5.6e-8 ●○○○○ -0.57 -0.574311965998399
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3182  AIK81750.1  358 aa 4-alpha-L-fucosyltransferase <1e-323 ●○○○○ -0.57 -0.573874849608602
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2273  NP_231904.1  Q9KPT9  proA  417 aa gamma-glutamyl phosphate reductase 0.0011 ●○○○○ -0.57 -0.573804502691173
Escherichia coli M12  CO715_02900  ATI04777.1  219 aa ethanolamine utilization microcompartment protein EutL 0.018 ●○○○○ -0.57 -0.573686027955652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3981  AIK82529.1  555 aa glycerol dehydratase large subunit <1e-323 ●○○○○ -0.57 -0.57356507244618
Porphyromonas gingivalis ATCC 33277  PGN_0717  WP_012457724.1  B2RIP1  115 aa hypothetical protein 0.014 ●○○○○ -0.57 -0.573133093093702
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