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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0721  NP_233108.1  Q9KLM2  53 aa hypothetical protein 0.0037 ●○○○○ -0.22 -0.224387171352277
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0926  NP_233311.1  Q9KL23  365 aa AraC family transcriptional regulator 0.00032 ●○○○○ -0.22 -0.224138869249303
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0717  NP_230366.1  Q9KU13  466 aa protease 0.0026 ●○○○○ -0.22 -0.223740780789053
Escherichia coli M12  CO715_22235  ATI08211.1  359 aa TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase 1.9e-17 ●○○○○ -0.22 -0.222952078003316
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1865  NP_231499.1  Q9KQY2  517 aa hypothetical protein 0.0073 ●○○○○ -0.22 -0.222799177553225
Escherichia coli M12  CO715_11225  ATI06223.1  511 aa thiamine ABC transporter permease 1.2e-20 ●○○○○ -0.22 -0.222743431989067
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2687  AIK81281.1  494 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ●○○○○ -0.22 -0.222424643955918
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2849  AIK81438.1  212 aa methionine sulfoxide reductase A <1e-323 ●○○○○ -0.22 -0.222349491325403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3075  AIK81660.1  1227 aa methionine synthase <1e-323 ●○○○○ -0.22 -0.221987659166574
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2667  AIK81261.1  456 aa aldehyde dehydrogenase family protein 6.2e-8 ●○○○○ -0.22 -0.221975988594115
Escherichia coli M12  CO715_00095  ATI04274.1  1653 aa hypothetical protein 6.3e-67 ●○○○○ -0.22 -0.221908847932072
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0130  NP_232531.1  Q9KN35  294 aa D-ribose transporter subunit RbsB 2.2e-6 ●○○○○ -0.22 -0.221843743970197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4089  AIK82635.1  379 aa radical SAM superfamily protein 0.0051 ●○○○○ -0.22 -0.22161181696359
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0181  NP_232581.1  Q9KMY5  291 aa hypothetical protein 0.041 ●○○○○ -0.22 -0.220936444410129
Escherichia coli M12  CO715_01345  ATI04496.1  334 aa protease modulator HflC 9.2e-28 ●○○○○ -0.22 -0.219405095761086
Escherichia coli M12  CO715_21520  ATI08080.1  332 aa galactose ABC transporter substrate-binding protein 8.2e-10 ●○○○○ -0.22 -0.219196449746837
Escherichia coli M12  CO715_14490  ATI06811.1  374 aa ABC transporter permease 1.1e-7 ●○○○○ -0.22 -0.218779157718339
Escherichia coli M12  CO715_17945  ATI07434.1  577 aa single-stranded-DNA-specific exonuclease RecJ 0.00061 ●○○○○ -0.22 -0.21857051170409
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2147  AIK80752.1  133 aa acyl-CoA thioester hydrolase, YbgC/YbaW family protein 0.001 ●○○○○ -0.22 -0.218003443049242
Escherichia coli M12  CO715_01475  ATI04517.1  105 aa quaternary ammonium compound-resistance protein SugE 1.4e-7 ●○○○○ -0.22 -0.217735927647095
Escherichia coli M12  CO715_08410  ATI05731.1  107 aa hypothetical protein 0.0018 ●○○○○ -0.22 -0.217735927647095
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1885  NP_231519.1  Q9KQW3  191 aa hypothetical protein 0.00022 ●○○○○ -0.22 -0.217630063026439
Escherichia coli M12  CO715_12850  ATI06519.1  314 aa tRNA pseudouridine(55) synthase TruB 0.0069 ●○○○○ -0.22 -0.217527281632846
Escherichia coli M12  CO715_22480  ATI08894.1  98 aa hypothetical protein 3.5e-135 ●○○○○ -0.22 -0.216901343590099
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4094  AIK82640.1  326 aa putative transporter <1e-323 ●○○○○ -0.22 -0.216829066197454
Porphyromonas gingivalis ATCC 33277  PGN_0135  WP_010956493.1  B2RH09  513 aa MFS transporter 1.9e-12 ●○○○○ -0.22 -0.216653798359498
Escherichia coli M12  CO715_22675  ATI08282.1  555 aa energy-dependent translational throttle protein EttA 1.2e-13 ●○○○○ -0.22 -0.216066759533104
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1758  NP_231394.1  Q9KR84  411 aa phage family integrase 9.0e-5 ●○○○○ -0.22 -0.21579106380167
Escherichia coli M12  CO715_18105  ATI07461.1  261 aa methylmalonyl-CoA decarboxylase 6.8e-10 ●○○○○ -0.22 -0.215440821490357
Escherichia coli M12  CO715_23530  ATI08420.1  284 aa co-chaperone YbbN 0.0018 ●○○○○ -0.22 -0.215440821490357
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2065  NP_231697.1  Q9KQD5  130 aa chemotaxis protein CheY 0.0049 ●○○○○ -0.21 -0.214991760294889
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4044  AIK82591.1  299 aa bacterial regulatory helix-turn-helix, AraC family protein 3.5e-8 ●○○○○ -0.21 -0.214761040974317
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0460  NP_230114.1  Q9KUQ5  proC  272 aa pyrroline-5-carboxylate reductase 0.022 ●○○○○ -0.21 -0.214713914275871
Porphyromonas gingivalis ATCC 33277  PGN_0980  WP_012457932.1  B2RJF4  771 aa alpha-1 2-mannosidase <1e-323 ●○○○○ -0.21 -0.214610967708822
Porphyromonas gingivalis ATCC 33277  PGN_1174  WP_004584448.1  B2RJZ8  335 aa electron transfer flavoprotein subunit alpha/FixB family protein 7.0e-9 ●○○○○ -0.21 -0.214610967708822
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1375  NP_231019.2  Q9KS84  210 aa hypothetical protein 0.031 ●○○○○ -0.21 -0.214601034088206
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1370  NP_231014.1  Q9KS89  443 aa GGDEF family protein 0.00093 ●○○○○ -0.21 -0.213792846158062
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2771  NP_232397.1  Q9KNG8  atpI  129 aa F0F1 ATP synthase subunit I 7.4e-5 ●○○○○ -0.21 -0.213401580439729
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2176  AIK80781.1  303 aa putative 2-dehydropantoate 2-reductase 5.6e-14 ●○○○○ -0.21 -0.212856399785086
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1576  NP_231216.1  Q9KRR0  105 aa hypothetical protein 0.039 ●○○○○ -0.21 -0.212794062500699
Escherichia coli M12  CO715_15585  ATI07008.1  220 aa fructose-6-phosphate aldolase 2.8e-16 ●○○○○ -0.21 -0.212519777290873
Escherichia coli M12  CO715_19295  ATI07672.1  85 aa hypothetical protein 8.7e-5 ●○○○○ -0.21 -0.211476547219629
Escherichia coli M12  CO715_04630  ATI05084.1  472 aa DNA cytosine methyltransferase 4.6e-9 ●○○○○ -0.21 -0.21126790120538
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2883  AIK81471.1  95 aa hypothetical protein 3.4e-5 ●○○○○ -0.21 -0.211019697674168
Escherichia coli M12  CO715_07320  ATI05540.1  514 aa cytochrome bd-II ubiquinol oxidase subunit I 5.6e-9 ●○○○○ -0.21 -0.210433317148385
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2112  AIK80716.1  156 aa sigma70 sigma factor YlaC family protein 0.0016 ●○○○○ -0.21 -0.209641903503345
Porphyromonas gingivalis ATCC 33277  PGN_1637  WP_004584810.1  B2RLB1  209 aa methenyltetrahydrofolate cyclohydrolase 2.2e-9 ●○○○○ -0.21 -0.208961664837691
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4065  AIK82612.1  382 aa cystathionine beta-lyase 0.026 ●○○○○ -0.21 -0.20861141532973
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0212  NP_232611.1  Q9KMV6  349 aa hypothetical protein 2.5e-6 ●○○○○ -0.21 -0.208199938309196
Escherichia coli M12  CO715_03960  ATI04969.1  179 aa DNA utilization protein HofN 1.2e-10 ●○○○○ -0.21 -0.207303626934652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3456  AIK82012.1  400 aa sodium/glutamate symporter 1.5e-12 ●○○○○ -0.21 -0.207159605243245
Escherichia coli M12  CO715_13710  ATI06668.1  311 aa aspartate carbamoyltransferase catalytic subunit 0.033 ●○○○○ -0.21 -0.207094980920403
Porphyromonas gingivalis ATCC 33277  PGN_1105  WP_012458032.1  B2RJS9  190 aa peptidylprolyl isomerase 0.0015 ●○○○○ -0.21 -0.207077345859465
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0650  NP_233039.1  Q9KLU1  378 aa hypothetical protein 0.0074 ●○○○○ -0.21 -0.206924299223971
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3651  AIK82206.1  308 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.21 -0.206622059898253
Escherichia coli M12  CO715_13515  ATI06634.1  331 aa capsid protein 1.4e-43 ●○○○○ -0.21 -0.206051750849159
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3538  AIK82094.1  513 aa heme ABC exporter, ATP-binding protein CcmA 1.4e-11 ●○○○○ -0.21 -0.206041448500959
Escherichia coli M12  CO715_00340  ATI04319.1  1093 aa DUF5107 domain-containing protein 5.9e-13 ●○○○○ -0.21 -0.205425812806412
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4226  AIK82771.1  470 aa EAL domain protein 4.7e-6 ●○○○○ -0.2 -0.204650263934339
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0527  NP_232918.1  Q9KM61  329 aa hypothetical protein 0.0043 ●○○○○ -0.2 -0.204580143861393
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2035  NP_231669.1  Q9KQG3  212 aa hypothetical protein 0.00058 ●○○○○ -0.2 -0.20417397934519
Escherichia coli M12  CO715_09210  ATI05874.1  462 aa glutamate mutase 7.8e-10 ●○○○○ -0.2 -0.204173936720919
Porphyromonas gingivalis ATCC 33277  PGN_1693  WP_012458463.1  B2RLG7  selD  348 aa selenide, water dikinase SelD 0.0028 ●○○○○ -0.2 -0.204165531678657
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2661  AIK81255.1  271 aa putative ascBF operon repressor 9.9e-8 ●○○○○ -0.2 -0.203937538168053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4205  AIK82750.1  127 aa crcB-like family protein 5.8e-8 ●○○○○ -0.2 -0.203646944429536
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3159  AIK81731.1  286 aa phospholipase A <1e-323 ●○○○○ -0.2 -0.203472356067588
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3534  AIK82090.1  610 aa alpha amylase, catalytic domain protein <1e-323 ●○○○○ -0.2 -0.203288070214936
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3356  AIK81913.1  139 aa hypothetical protein 1.3e-11 ●○○○○ -0.2 -0.203115292778114
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3426  AIK81983.1  1035 aa acrB RND-type permease <1e-323 ●○○○○ -0.2 -0.20241100675378
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1293  NP_230938.2  Q9KSG3  396 aa aromatic amino acid aminotransferase 0.005 ●○○○○ -0.2 -0.202133485083457
Escherichia coli M12  CO715_23485  ATI08411.1  135 aa transcriptional regulator 9.1e-26 ●○○○○ -0.2 -0.201878830564181
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1092  AIK79715.1  530 aa impA-related N-terminal family protein 1.0e-10 ●○○○○ -0.2 -0.201595971268788
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1821  NP_231455.1  Q9KR26  467 aa PTS system fructose-specific transporter subunit IIBC 0.00049 ●○○○○ -0.2 -0.201145741587005
Escherichia coli M12  CO715_09780  ATI05973.1  461 aa anaerobic C4-dicarboxylate transporter DcuC 1.5e-16 ●○○○○ -0.2 -0.199375078393195
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3158  AIK81730.1  608 aa ATP-dependent DNA helicase RecQ 9.4e-5 ●○○○○ -0.2 -0.199003681887632
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4921  AIK83447.1  393 aa setB MFS transporter 0.0019 ●○○○○ -0.2 -0.19842433551091
Escherichia coli M12  CO715_00360  ATI08691.1  353 aa alcohol dehydrogenase 1.1e-21 ●○○○○ -0.2 -0.198331848321951
Escherichia coli M12  CO715_06205  ATI05347.1  236 aa antibiotic biosynthesis monooxygenase 0.035 ●○○○○ -0.2 -0.197705910279204
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2309  NP_231940.1  Q9KPQ7  csd  404 aa class V aminotransferase 0.033 ●○○○○ -0.2 -0.197631237603167
Escherichia coli M12  CO715_17365  ATI07331.1  429 aa serine transporter 3.1e-22 ●○○○○ -0.2 -0.197497264264955
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1673  AIK80292.1  421 aa putative cytoplasmic protein 0.00063 ●○○○○ -0.2 -0.197245707454476
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0036  NP_229695.2  Q9KVV3  474 aa FixG-like protein 1.4e-5 ●○○○○ -0.2 -0.19685076113933
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4177  AIK82722.1  1214 aa evgS-Phis <1e-323 ●○○○○ -0.2 -0.196398194307851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2547  AIK81144.1  234 aa dpiA-phosphorylated DNA binding transcriptional dual regulator 0.0035 ●○○○○ -0.2 -0.196219670857245
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1998  AIK80604.1  187 aa hypothetical protein 9.2e-5 ●○○○○ -0.2 -0.196047602319969
Escherichia coli M12  CO715_12005  ATI06367.1  237 aa thymidylate kinase 2.7e-71 ●○○○○ -0.2 -0.195828096150964
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1826  AIK80439.1  147 aa sugar (and other) transporter family protein 0.00017 ●○○○○ -0.2 -0.195718817510035
Porphyromonas gingivalis ATCC 33277  PGN_0329  WP_012457432.1  B2RHK3  897 aa transglutaminase 0.006 ●○○○○ -0.2 -0.195665802557606
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0544  NP_230195.1  Q56647  recX  152 aa recombination regulator RecX 0.0005 ●○○○○ -0.2 -0.195583226716022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1390  AIK80013.1  186 aa hypothetical protein 8.6e-6 ●○○○○ -0.2 -0.19552523077487
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2548  NP_232176.1  Q9KP31  582 aa hypothetical protein 0.0017 ●○○○○ -0.2 -0.195479424904023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4336  AIK82881.1  264 aa cbiX family protein 1.1e-9 ●○○○○ -0.2 -0.195331469732288
Escherichia coli CFT073  c0426  AAN78907.1  A0A0H2V5A3  776 aa Hypothetical protein 9.3e-30 ●○○○○ -0.19 -0.194958766480295
Escherichia coli M12  CO715_05880  ATI08742.1  62 aa phage tail protein 5.6e-13 ●○○○○ -0.19 -0.194576220065471
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1434  NP_231077.1  P0C6D0  fnr  250 aa fumarate/nitrate reduction transcriptional regulator 0.0039 ●○○○○ -0.19 -0.193915924188219
Escherichia coli M12  CO715_13000  ATI06543.1  269 aa phospholipid ABC transporter ATP-binding protein MlaF 1.1e-25 ●○○○○ -0.19 -0.193741636008476
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0468  NP_232860.1  Q9KMA6  higB-2  110 aa hypothetical protein 0.0016 ●○○○○ -0.19 -0.193444011373459
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4003  AIK82550.1  567 aa urease, alpha subunit 7.6e-5 ●○○○○ -0.19 -0.193328748226659
Escherichia coli M12  CO715_03825  ATI04945.1  797 aa maltodextrin phosphorylase 5.4e-25 ●○○○○ -0.19 -0.193324343979978
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0179  NP_232579.1  Q9KMY7  402 aa NupC family protein 0.013 ●○○○○ -0.19 -0.193312130181058
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