Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2572  AIK81169.1  820 aa thrA <1e-323 ●○○○○ -0.16 -0.158978435570725
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0118  NP_232519.1  Q9KN47  227 aa hypothetical protein 5.7e-7 ●○○○○ -0.16 -0.158682206801506
Escherichia coli M12  CO715_18165  ATI07473.1  143 aa DUF296 domain-containing protein 1.5e-11 ●○○○○ -0.16 -0.15806316757192
Escherichia coli M12  CO715_10835  ATI06149.1  495 aa Fe-S cluster assembly protein SufB 0.00057 ●○○○○ -0.16 -0.157854521557672
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4244  AIK82789.1  828 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.16 -0.157810510970939
Escherichia coli CFT073  c2611  AAN81067.1  A0A0H2VA75  yegQ  453 aa Putative protease yegQ 0.022 ●○○○○ -0.16 -0.157375175551683
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2837  AIK81426.1  175 aa acetyltransferase family protein <1e-323 ●○○○○ -0.16 -0.157180052889716
Escherichia coli M12  CO715_01880  ATI04589.1  478 aa ammonia-forming cytochrome c nitrite reductase subunit c552 2.2e-5 ●○○○○ -0.16 -0.157019937500676
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1082  NP_230727.1  Q9KT23  121 aa response regulator 0.028 ●○○○○ -0.16 -0.156942805584882
Escherichia coli M12  CO715_21990  ATI08166.1  405 aa putative colanic acid polymerase WcaD 2.9e-46 ●○○○○ -0.16 -0.156811291486427
Porphyromonas gingivalis ATCC 33277  PGN_0750  WP_012457751.1  B2RIS4  cutC  248 aa copper homeostasis protein CutC 2.7e-12 ●○○○○ -0.16 -0.156634926840652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2611  AIK81205.1  262 aa siderophore-iron reductase FhuF 3.2e-5 ●○○○○ -0.16 -0.156316672628085
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1148  NP_230793.1  Q9KSV8  284 aa DNA-binding transcriptional regulator HexR 0.00035 ●○○○○ -0.16 -0.156293525843279
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0834  NP_233220.1  Q9KLB2  317 aa hypothetical protein 0.0023 ●○○○○ -0.16 -0.156052363866432
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1956  NP_231590.1  Q9KQP2  323 aa lytic murein transglycosylase 0.019 ●○○○○ -0.16 -0.155765637397703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3077  AIK81662.1  594 aa aceK <1e-323 ●○○○○ -0.16 -0.155673097662103
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3184  AIK81752.1  376 aa TDP-4-keto-6-deoxy-D-glucose transaminase familyprotein <1e-323 ●○○○○ -0.16 -0.155651731808893
Escherichia coli M12  CO715_23880  ATI08481.1  815 aa glycogen phosphorylase 1.8e-11 ●○○○○ -0.16 -0.155350769386685
Escherichia coli M12  CO715_15550  ATI07001.1  376 aa cytoplasmic protein 4.8e-6 ●○○○○ -0.16 -0.155350769386685
Escherichia coli M12  CO715_05075  ATI05159.1  475 aa exodeoxyribonuclease I 1.8e-5 ●○○○○ -0.16 -0.155350769386685
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0655  NP_233044.1  Q9KLT6  548 aa sucrose-6-phosphate dehydrogenase 9.5e-6 ●○○○○ -0.16 -0.155337161701561
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0267  NP_232665.1  Q9KMQ3  379 aa multidrug resistance protein D 0.029 ●○○○○ -0.16 -0.155256411384344
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1643  NP_231280.1  Q9KRJ7  596 aa methyl-accepting chemotaxis protein 1.6e-6 ●○○○○ -0.16 -0.155113952512619
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0774  NP_233160.1  Q9KLH0  338 aa UDP-glucose 4-epimerase 0.00046 ●○○○○ -0.15 -0.154234555005114
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1796  NP_231431.1  Q9KR50  124 aa middle operon regulator-like protein 0.0067 ●○○○○ -0.15 -0.153836398280028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4384  AIK82927.1  446 aa glucarate dehydratase 2.1e-14 ●○○○○ -0.15 -0.153666622342199
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3644  AIK82199.1  507 aa bacterial regulatory, gntR family protein <1e-323 ●○○○○ -0.15 -0.153648884842947
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0105  NP_232506.1  Q9KN60  94 aa hypothetical protein 0.045 ●○○○○ -0.15 -0.153376296513333
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0301  NP_232697.1  Q9KMN0  250 aa short chain dehydrogenase/reductase oxidoreductase 0.0058 ●○○○○ -0.15 -0.153168012919048
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0076  NP_229735.1  Q9KVR3  141 aa universal stress protein A 6.5e-6 ●○○○○ -0.15 -0.153027005169412
Porphyromonas gingivalis ATCC 33277  PGN_0301  WP_039417063.1  B2RHH5  103 aa hypothetical protein 3.1e-10 ●○○○○ -0.15 -0.152642875192122
Porphyromonas gingivalis ATCC 33277  PGN_0301  WP_004583835.1  B2RHH5  163 aa OmpH family outer membrane protein 3.1e-10 ●○○○○ -0.15 -0.152642875192122
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3002  AIK81587.1  548 aa na+/H+ antiporter 2.3e-8 ●○○○○ -0.15 -0.152366921393709
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0146  NP_229804.1  Q9KVJ7  199 aa hypothetical protein 0.0014 ●○○○○ -0.15 -0.151629474973395
Escherichia coli M12  CO715_10165  ATI06033.1  273 aa antitermination protein 3.8e-12 ●○○○○ -0.15 -0.151386495115957
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1411  NP_231054.1  Q9KS49  511 aa multidrug resistance protein VceB 0.01 ●○○○○ -0.15 -0.151204522852572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3402  AIK81959.1  367 aa 2-aminoethylphosphonate--pyruvate transaminase <1e-323 ●○○○○ -0.15 -0.151137369335066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3967  AIK82515.1  332 aa putrescine aminotransferase 0.00056 ●○○○○ -0.15 -0.150675227080953
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0331  NP_232727.1  Q9KMK8  220 aa hypothetical protein 0.0046 ●○○○○ -0.15 -0.150455245989852
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4375  AIK82918.1  429 aa sdaC serine STP transporter <1e-323 ●○○○○ -0.15 -0.150416424180123
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1509  NP_231150.1  Q9KRX4  cobB  259 aa NAD-dependent deacetylase 0.0062 ●○○○○ -0.15 -0.149951684046017
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1754  NP_231390.1  Q9KR88  547 aa paraquat-inducible protein B 0.00075 ●○○○○ -0.15 -0.14978781455878
Porphyromonas gingivalis ATCC 33277  PGN_0405  WP_012457486.1  B2RHS9  781 aa alpha-1 2-mannosidase 4.5e-13 ●○○○○ -0.15 -0.149699011997091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2670  AIK81264.1  220 aa lysE type translocator family protein 2.8e-15 ●○○○○ -0.15 -0.149675892096414
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3544  AIK82100.1  331 aa acyltransferase family protein <1e-323 ●○○○○ -0.15 -0.14945599801004
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1145  NP_230790.1  Q9KSW1  558 aa hypothetical protein 0.00072 ●○○○○ -0.15 -0.149102744600772
Escherichia coli M12  CO715_22275  ATI08217.1  886 aa protein lysine acetyltransferase 2.3e-6 ●○○○○ -0.15 -0.149091388959219
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0225  NP_232624.1  Q9KMU4  254 aa hypothetical protein 3.9e-5 ●○○○○ -0.15 -0.147840012760521
Escherichia coli M12  CO715_20170  ATI07834.1  431 aa two-component system sensor histidine kinase PhoR 2.0e-9 ●○○○○ -0.15 -0.147839512873726
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2708  AIK81298.1  1049 aa cusA 5.1e-10 ●○○○○ -0.15 -0.147544850903036
Escherichia coli M12  CO715_20180  ATI07836.1  400 aa exonuclease subunit SbcD 4.8e-10 ●○○○○ -0.15 -0.147422220845229
Escherichia coli M12  CO715_06250  ATI05356.1  759 aa oxidoreductase 6.6e-6 ●○○○○ -0.15 -0.14721357483098
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0087  NP_229746.1  P57063  tatB  133 aa sec-independent translocase 0.0051 ●○○○○ -0.15 -0.146857018630633
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0728  NP_230377.1  Q9KU02  258 aa hypothetical protein 0.0023 ●○○○○ -0.15 -0.146820425530446
Escherichia coli M12  CO715_16890  ATI07244.1  123 aa PTS glucitol/sorbitol transporter subunit IIA 3.9e-11 ●○○○○ -0.15 -0.146796282802482
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1784  NP_231419.1  P0C6E9  nanH  807 aa neuraminidase 0.0029 ●○○○○ -0.15 -0.146691195593145
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4560  AIK83098.1  88 aa smpA 0.0012 ●○○○○ -0.15 -0.146627333803827
Escherichia coli CFT073  c1591  AAN80059.1  A0A0H2V6V1  555 aa Hypothetical protein 0.05 ●○○○○ -0.15 -0.146536264707635
Escherichia coli M12  CO715_04095  ATI04995.1  200 aa cell filamentation protein Fic 5.3e-12 ●○○○○ -0.15 -0.145753052731238
Escherichia coli M12  CO715_05950  ATI05300.1  196 aa DNA invertase 0.0047 ●○○○○ -0.15 -0.145753052731238
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4950  AIK83476.1  181 aa hypothetical protein 1.0e-12 ●○○○○ -0.14 -0.14452416120304
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2557  AIK81154.1  298 aa nhaR transcriptional activator 1.1e-12 ●○○○○ -0.14 -0.144281476264601
Escherichia coli M12  CO715_22135  ATI08191.1  296 aa HTH-type transcriptional activator IlvY 0.0029 ●○○○○ -0.14 -0.144083884617247
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3858  AIK82408.1  779 aa aerobic respiration control sensor protein arcB 2.2e-14 ●○○○○ -0.14 -0.143627070739349
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1949  NP_231583.1  Q9KQP9  608 aa pyoverdine biosynthesis protein PvcA 0.02 ●○○○○ -0.14 -0.143609892144851
Escherichia coli M12  CO715_23025  ATI08346.1  394 aa mannonate dehydratase 3.0e-6 ●○○○○ -0.14 -0.142832008531754
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4203  AIK82748.1  500 aa response regulator <1e-323 ●○○○○ -0.14 -0.142602082076894
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1971  NP_231605.1  Q9KQM7  476 aa 2-succinylbenzoate-CoA ligase 0.0066 ●○○○○ -0.14 -0.142432029477082
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1628  NP_231265.1  Q9KRL2  372 aa hypothetical protein 0.0007 ●○○○○ -0.14 -0.142389333339956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1805  AIK80418.1  331 aa hypothetical protein 0.0067 ●○○○○ -0.14 -0.142326349096792
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0018  NP_232419.1  Q9KNE7  694 aa VgrG protein 0.027 ●○○○○ -0.14 -0.142105291262545
Escherichia coli M12  CO715_06020  ATI05312.1  299 aa O-acetylserine/cysteine exporter 1.6e-43 ●○○○○ -0.14 -0.141997424474758
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3958  AIK82506.1  673 aa NADH:flavin oxidoreductase / NADH oxidase familyprotein 3.6e-7 ●○○○○ -0.14 -0.141226598804722
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2909  AIK81495.1  1109 aa mechanosensitive ion channel family protein 1.1e-16 ●○○○○ -0.14 -0.140909000486399
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0965  NP_233349.1  Q9KKY5  396 aa diguanylate cyclase 0.0038 ●○○○○ -0.14 -0.140818582396569
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0895  NP_233280.1  Q9KL53  981 aa chemotactic transducer-like protein 0.0031 ●○○○○ -0.14 -0.140635895221175
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1360  NP_231004.1  Q9KS99  365 aa amino acid ABC transporter permease 0.0077 ●○○○○ -0.14 -0.139717466551778
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0559  NP_230210.1  Q9KUG2  267 aa hypothetical protein 0.013 ●○○○○ -0.14 -0.139590852932614
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1868  NP_231502.1  Q9KQX9  626 aa methyl-accepting chemotaxis protein 0.00031 ●○○○○ -0.14 -0.139422845461244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2873  AIK81462.1  284 aa L-xylulose 5-phosphate 3-epimerase 1.4e-9 ●○○○○ -0.14 -0.139093193520401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1641  AIK80261.1  133 aa hypothetical protein 1.3e-6 ●○○○○ -0.14 -0.139080858161556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2489  AIK81086.1  163 aa acetolactate synthase, small subunit 1.9e-12 ●○○○○ -0.14 -0.138947693504572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3233  AIK81794.1  287 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●○○○○ -0.14 -0.138488150335977
Escherichia coli M12  CO715_17815  ATI07410.1  292 aa xanthine dehydrogenase FAD-binding subunit XdhB 0.01 ●○○○○ -0.14 -0.138241796218279
Escherichia coli M12  CO715_05865  ATI05288.1  140 aa phage minor tail protein G 1.2e-37 ●○○○○ -0.14 -0.137824504189781
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1125  NP_230770.1  Q9KSY1  175 aa hypothetical protein 0.00063 ●○○○○ -0.14 -0.137712716822342
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1353  NP_230997.1  Q9KSA6  976 aa GGDEF family protein 0.0076 ●○○○○ -0.14 -0.13723646780749
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2064  NP_231696.1  Q9KQD6  239 aa chemotaxis protein CheZ 0.0049 ●○○○○ -0.14 -0.136533450959806
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0693  NP_233080.1  Q9KLQ0  secD  612 aa preprotein translocase subunit SecD 0.021 ●○○○○ -0.14 -0.136458311233185
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3324  AIK81881.1  330 aa aspartate--ammonia ligase 1.1e-13 ●○○○○ -0.14 -0.135904119685155
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3586  AIK82141.1  872 aa cellulose synthase catalytic subunit <1e-323 ●○○○○ -0.14 -0.135839022563125
Escherichia coli M12  CO715_19340  ATI07681.1  513 aa TyrR family transcriptional regulator 0.0022 ●○○○○ -0.14 -0.135320752018795
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2125  AIK80730.1  353 aa malK 0.02 ●○○○○ -0.14 -0.135122283594329
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2664  AIK81258.1  67 aa hypothetical protein <1e-323 ●○○○○ -0.14 -0.135117918649995
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2228  AIK80833.1  105 aa psiF repeat family protein 2.8e-9 ●○○○○ -0.14 -0.135062329982098
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1011  NP_230657.1  Q9KT92  nth  213 aa endonuclease III 1.1e-5 ●○○○○ -0.14 -0.135048810723393
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4885  AIK83412.1  365 aa outer membrane protein C <1e-323 ●○○○○ -0.13 -0.134852185067308
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2999  AIK81584.1  229 aa lrgB-like family protein 0.00014 ●○○○○ -0.13 -0.134040309902753
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4265  AIK82810.1  428 aa bacterial extracellular solute-binding family protein <1e-323 ●○○○○ -0.13 -0.133598865307495
Escherichia coli M12  CO715_22495  ATI08255.1  423 aa transporter 0.049 ●○○○○ -0.13 -0.133234291876306
Retrieved entries 6,601–6,700 out of 36,363 total in 8.9 ms (Link to these results)