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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_12145  ATI06393.1  160 aa type II secretion system protein GspG 2.1e-149 ●●○○○ -1.99 -1.98788871253443
Escherichia coli M12  CO715_09930  ATI06000.1  416 aa MFS transporter 9.4e-13 ●●○○○ -1.99 -1.98726277449169
Mycobacterium avium subsp. paratuberculosis K10  MAP_1195c  AAS03512.1  Q740Z7  fadE15  609 aa FadE15 0.018 ●●○○○ -1.99 -1.98676487761502
Escherichia coli M12  CO715_12345  ATI06426.1  254 aa siderophore-interacting protein 4.9e-13 ●●○○○ -1.99 -1.98663683644894
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3225  WP_000105550.1  E8X9P9  speB  306 aa agmatinase 0.00023 ●●○○○ -1.99 -1.98644329310829
Mycobacterium avium subsp. paratuberculosis K10  MAP_3763c  AAS06313.1  Q73TF5  papA3  506 aa PapA3_2 0.018 ●●○○○ -1.99 -1.98505838477737
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2415  NP_232045.1  Q9KPF3  256 aa transcriptional regulator PdhR 7.0e-9 ●●○○○ -1.99 -1.9850543297024
Streptococcus pyogenes M1 5448  SP5448_06770  WP_002985288.1  435 aa phosphopyruvate hydratase 0.039 ●●○○○ -1.98 -1.98341375382671
Haemophilus influenzae Rd KW20  HI_0086  NP_438259.1  P44502  metB  381 aa cystathionine gamma-synthase 0.047 ●●○○○ -1.98 -1.98336411818886
Vibrio parahaemolyticus RIMD 2210633  VP_2643  BAC60906.1  Q87LG9  366 aa putative permease 0.049 ●●○○○ -1.98 -1.98286846007761
Escherichia coli M12  CO715_15410  ATI06978.1  320 aa ATP-dependent 6-phosphofructokinase 4.7e-8 ●●○○○ -1.98 -1.98246391616396
Acinetobacter baumannii ATCC 17978  A1S_2140  ABO12567.2  677 aa potassium-transporting ATPase B chain 1.9e-25 ●●○○○ -1.98 -1.98204960555399
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2474  WP_000118256.1  E8XF30  122 aa hypothetical protein 3.6e-14 ●●○○○ -1.98 -1.98044232534839
Escherichia coli M12  CO715_22725  ATI08292.1  259 aa 2-deoxyribose-5-phosphate aldolase 2.6e-13 ●●○○○ -1.98 -1.98037745602147
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4129  WP_000947139.1  E8XJE0  corA  316 aa magnesium/cobalt transporter CorA 9.3e-5 ●●○○○ -1.98 -1.97881186563126
Mycobacterium avium subsp. paratuberculosis K10  MAP_0946c  AAS03263.1  Q741Z1  307 aa hypothetical protein 0.018 ●●○○○ -1.98 -1.97877617262295
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0186  WP_000777532.1  E8XHX5  stiA  179 aa fimbrial protein StiA 1.6e-14 ●●○○○ -1.98 -1.97850435186044
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2307  NP_231938.1  Q9KPQ9  panE  296 aa 2-dehydropantoate 2-reductase 1.1e-14 ●●○○○ -1.98 -1.97793693242283
Escherichia coli O157:H7 str. EDL933  Z1477  AAG55598.1  714 aa putative portal protein of bacteriophage BP-933W 0.025 ●●○○○ -1.98 -1.97779636924577
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3813  CBW19904.1  A0A0H3NHP7  311 aa reverse transcriptase 1.3e-5 ●●○○○ -1.98 -1.97716002773661
Escherichia coli O157:H7 str. EDL933  Z3630  AAG57493.1  387 aa multidrug resistance protein K 0.025 ●●○○○ -1.98 -1.97688384398242
Escherichia coli M12  CO715_04835  ATI05116.1  216 aa CoA transferase subunit B 2.2e-12 ●●○○○ -1.98 -1.976621827765
Escherichia coli M12  CO715_20165  ATI07833.1  439 aa branched-chain amino acid transport system 2 carrier protein 1.2e-6 ●●○○○ -1.98 -1.9762045357365
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0666  NP_230315.2  Q9KU58  83 aa hypothetical protein 5.3e-10 ●●○○○ -1.97 -1.97437446878848
Mycobacterium avium subsp. paratuberculosis K10  MAP_2885c  AAS05202.1  Q73VX6  594 aa hypothetical protein 0.019 ●●○○○ -1.97 -1.9737497754821
Mycobacterium avium subsp. paratuberculosis K10  MAP_2523c  AAS04840.1  Q73WY7  347 aa hypothetical protein 0.019 ●●○○○ -1.97 -1.97316616848798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3293  AIK81854.1  607 aa GTP-binding protein TypA/BipA <1e-323 ●●○○○ -1.97 -1.97217797020214
Escherichia coli M12  CO715_17350  ATI07328.1  181 aa protein Syd 6.2e-11 ●●○○○ -1.97 -1.97057109335178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3493  AIK82049.1  55 aa ribosomal protein L33 1.1e-7 ●●○○○ -1.97 -1.96935760279367
Escherichia coli O157:H7 str. EDL933  Z3199  AAG57095.1  404 aa glycosyl transferase 0.026 ●●○○○ -1.97 -1.96922846498473
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1474  WP_002869203.1  A0A0H3PB11  921 aa RecB-like helicase 0.03 ●●○○○ -1.97 -1.96897366077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3530  AIK82086.1  462 aa L-seryl-tRNA selenium transferase <1e-323 ●●○○○ -1.97 -1.96867257777206
Escherichia coli M12  CO715_20410  ATI07879.1  288 aa 2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase 1.6e-7 ●●○○○ -1.97 -1.96827598719504
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1194  WP_002855878.1  A0A0H3PAE8  fliR  255 aa flagellar type III secretion system protein FliR 0.03 ●●○○○ -1.97 -1.96614564966
Escherichia coli O157:H7 str. EDL933  Z1829  AAG55928.1  453 aa hypothetical protein 0.026 ●●○○○ -1.97 -1.96527821975922
Mycobacterium avium subsp. paratuberculosis K10  MAP_2721  AAS05038.1  Q73WD9  166 aa hypothetical protein 0.019 ●●○○○ -1.97 -1.96527494653578
Acinetobacter baumannii ATCC 17978  A1S_1549  ABO11976.2  229 aa putative nucleotidyl transferase 2.1e-12 ●●○○○ -1.96 -1.96481814830345
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0928  WP_002865903.1  A1VZQ4  peb1A  259 aa bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein PEB1a 0.03 ●●○○○ -1.96 -1.96464285372
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3324  WP_000345259.1  E8XB99  ygiK  435 aa TRAP transporter large permease subunit 0.00018 ●●○○○ -1.96 -1.96454481794932
Escherichia coli M12  CO715_19750  ATI07754.1  434 aa inosine/guanosine kinase 6.9e-12 ●●○○○ -1.96 -1.96452035893856
Escherichia coli M12  CO715_06215  ATI05349.1  84 aa AraC family transcriptional regulator 5.4e-14 ●●○○○ -1.96 -1.96431171292431
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1193  WP_002852900.1  A0A0H3PD61  542 aa hypothetical protein 0.03 ●●○○○ -1.96 -1.96416220352
Mycobacterium avium subsp. paratuberculosis K10  MAP_1482  AAS03799.1  Q73ZW9  301 aa hypothetical protein 0.019 ●●○○○ -1.96 -1.96380825112383
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1708  NP_231344.1  Q9KRD4  228 aa hypothetical protein 4.9e-8 ●●○○○ -1.96 -1.96309581242545
Escherichia coli M12  CO715_06990  ATI05482.1  125 aa antitermination protein 2.0e-90 ●●○○○ -1.96 -1.96139066872483
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3277  WP_001092814.1  E8XAH7  433 aa FAD-binding oxidoreductase 2.2e-5 ●●○○○ -1.96 -1.96062017431258
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2569  WP_000582931.1  E8XFS5  eutD  338 aa phosphate acetyltransferase 2.8e-12 ●●○○○ -1.96 -1.95946016128317
Acinetobacter baumannii ATCC 17978  A1S_3171  ABO13568.1  A3M9H4  rpoZ  92 aa RNA polymerase omega subunit 1.5e-21 ●●○○○ -1.96 -1.95931235189848
Escherichia coli O157:H7 str. EDL933  Z1930  AAG56019.1  494 aa putative protease encoded within prophage CP-933X 0.026 ●●○○○ -1.96 -1.9586457864289
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4837  AIK83364.1  119 aa NADH:ubiquinone oxidoreductase, membrane subunitA 0.012 ●●○○○ -1.96 -1.95731940382212
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3205  WP_000193679.1  E8X9M9  pepP  438 aa Xaa-Pro aminopeptidase 6.2e-5 ●●○○○ -1.96 -1.95716916543663
Escherichia coli M12  CO715_17895  ATI07424.1  439 aa guanine deaminase 0.00029 ●●○○○ -1.96 -1.95638316438286
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4742  WP_001575392.1  E8XCI4  ptnD  278 aa PTS mannose/fructose/sorbose transporter family subunit IID 0.00036 ●●○○○ -1.96 -1.95637051599887
Mycobacterium avium subsp. paratuberculosis K10  MAP_3307c  AAS05857.1  Q73UQ9  366 aa hypothetical protein 0.019 ●●○○○ -1.96 -1.95594673259409
Haemophilus influenzae Rd KW20  HI_1346  NP_439497.1  P45170  potB  286 aa spermidine/putrescine ABC transporter membrane protein 0.05 ●●○○○ -1.96 -1.95513122738083
Haemophilus influenzae Rd KW20  HI_0544  NP_438702.1  P44349  rplI  149 aa 50S ribosomal protein L9 0.05 ●●○○○ -1.96 -1.95513122738083
Haemophilus influenzae Rd KW20  HI_0669  NP_438829.1  P44813  mioC  146 aa flavodoxin 0.05 ●●○○○ -1.96 -1.95513122738083
Haemophilus influenzae Rd KW20  HI_0371  NP_438532.1  P44668  iscX  64 aa hypothetical protein 0.05 ●●○○○ -1.96 -1.95513122738083
Haemophilus influenzae Rd KW20  HI_0916  NP_439076.1  Q57483  omp26  197 aa outer membrane protein 0.05 ●●○○○ -1.96 -1.95513122738083
Escherichia coli CFT073  c2400  AAN80859.1  A0A0H2V895  278 aa Hypothetical protein 0.047 ●●○○○ -1.95 -1.95444642070828
Escherichia coli M12  CO715_06140  ATI05334.1  317 aa transcriptional regulator LsrR 2.3e-14 ●●○○○ -1.95 -1.95387941221187
Acinetobacter baumannii ATCC 17978  A1S_0498  ABO10951.2  A3M207  ndk  143 aa nucleoside diphosphate kinase 3.1e-9 ●●○○○ -1.95 -1.95331328659361
Mycobacterium avium subsp. paratuberculosis K10  MAP_3167c  AAS05715.1  Q73V49  158 aa hypothetical protein 0.019 ●●○○○ -1.95 -1.95300136596351
Mycobacterium avium subsp. paratuberculosis K10  MAP_0490  AAS02807.1  Q743V1  398 aa hypothetical protein 0.02 ●●○○○ -1.95 -1.95067303708026
Mycobacterium avium subsp. paratuberculosis K10  MAP_0491c  AAS02808.1  Q743V0  248 aa hypothetical protein 0.02 ●●○○○ -1.95 -1.95067303708026
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1170  WP_000887043.1  E8XEU3  flgB  138 aa flagellar basal body rod protein FlgB 3.5e-25 ●●○○○ -1.95 -1.95058027317046
Escherichia coli M12  CO715_17705  ATI07391.1  79 aa type III secretion system needle complex protein 8.1e-12 ●●○○○ -1.95 -1.95033242996964
Escherichia coli M12  CO715_21805  ATI08132.1  350 aa fructose-bisphosphate aldolase 6.6e-13 ●●○○○ -1.95 -1.95012378395539
Mycobacterium avium subsp. paratuberculosis K10  MAP_0497  AAS02814.1  Q743U4  394 aa hypothetical protein 0.02 ●●○○○ -1.95 -1.94898407293639
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2635  NP_232263.1  Q9KNU5  mrcA  835 aa penicillin-binding protein 1A 2.7e-10 ●●○○○ -1.95 -1.94852274777226
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0507  WP_001196740.1  E8X873  htpG  632 aa molecular chaperone HtpG 2.2e-14 ●●○○○ -1.95 -1.94832535255975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3160  AIK81732.1  154 aa hypothetical protein 5.5e-15 ●●○○○ -1.95 -1.94711706322256
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1434  WP_002860360.1  A0A0H3PAB7  420 aa glycosyltransferase family 8 protein 0.031 ●●○○○ -1.95 -1.94700552173
Escherichia coli M12  CO715_13120  ATI06565.1  229 aa N-acetylmannosamine-6-phosphate 2-epimerase 1.2e-27 ●●○○○ -1.95 -1.94678544772741
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1964  AIK80570.1  213 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein 3.0e-6 ●●○○○ -1.95 -1.94658361247786
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1138  WP_002868950.1  A0A0H3P9F0  pglF  590 aa UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) 0.031 ●●○○○ -1.95 -1.94552235576
Escherichia coli M12  CO715_08195  ATI05695.1  230 aa DUF421 domain-containing protein 3.7e-5 ●●○○○ -1.95 -1.94532492562767
Escherichia coli M12  CO715_16980  ATI07260.1  307 aa hydrogenase 3 membrane subunit 1.0e-19 ●●○○○ -1.94 -1.94490763359917
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2279  WP_001036943.1  E8XDM7  mglB  332 aa galactose/glucose ABC transporter substrate-binding protein MglB 0.00043 ●●○○○ -1.94 -1.94347496915116
Escherichia coli M12  CO715_18000  ATI07444.1  129 aa glycine cleavage system protein H 2.4e-8 ●●○○○ -1.94 -1.94344711149943
Escherichia coli O157:H7 str. EDL933  Z2560  AAG56562.1  169 aa hypothetical protein 0.027 ●●○○○ -1.94 -1.94285365226349
Escherichia coli M12  CO715_20005  ATI07802.1  663 aa cytochrome ubiquinol oxidase subunit I 5.4e-35 ●●○○○ -1.94 -1.94261252744243
Mycobacterium avium subsp. paratuberculosis K10  MAP_0778  AAS03095.1  Q742Q7  174 aa hypothetical protein 0.02 ●●○○○ -1.94 -1.94108334184719
Escherichia coli O157:H7 str. EDL933  Z1254  AAG55393.1  427 aa 5-enolpyruvylshikimate-3-phosphate synthetase 0.027 ●●○○○ -1.94 -1.94107059919295
Escherichia coli M12  CO715_00950  ATI04425.1  391 aa multidrug resistance protein MdtL 1.0e-11 ●●○○○ -1.94 -1.94031742128569
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0098  WP_002851710.1  A0A0H3P9L2  fliM  359 aa flagellar motor switch protein FliM 0.032 ●●○○○ -1.94 -1.94025061135
Escherichia coli O157:H7 str. EDL933  Z5112  AAG58825.1  558 aa putative translocated intimin receptor protein 0.027 ●●○○○ -1.94 -1.94014498803114
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4183  WP_001188784.1  E8XJI7  glnG  469 aa nitrogen regulation protein NR(I) 0.00014 ●●○○○ -1.94 -1.93965244823527
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0965  NP_230612.1  Q9KTD7  573 aa phosphoenolpyruvate-protein phosphotransferase 1.0e-7 ●●○○○ -1.94 -1.9393343000844
Escherichia coli M12  CO715_06570  ATI05408.1  84 aa hypothetical protein 2.8e-10 ●●○○○ -1.94 -1.93927419121445
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3825  WP_001541099.1  E8XFW8  63 aa transposase 8.6e-6 ●●○○○ -1.94 -1.93825395290245
Streptococcus pyogenes M1 5448  SP5448_07455  WP_010921981.1  239 aa glutaminyl-peptide cyclotransferase 0.034 ●●○○○ -1.94 -1.93823093841766
Escherichia coli CFT073  c1924  AAN80382.1  A0A0H2V8M0  yddB  790 aa Hypothetical protein yddB 0.026 ●●○○○ -1.94 -1.93804911859107
Escherichia coli M12  CO715_18055  ATI07453.1  410 aa D-3-phosphoglycerate dehydrogenase 2.8e-9 ●●○○○ -1.94 -1.93802231512896
Escherichia coli CFT073  c2775  AAN81229.1  A0A0H2V8Z9  yfaL  1254 aa Hypothetical protein yfaL precursor 0.0054 ●●○○○ -1.94 -1.9363212652982
Streptococcus pyogenes M1 5448  SP5448_01200  WP_010921872.1  304 aa protein jag 0.03 ●●○○○ -1.94 -1.93630826542153
Mycobacterium avium subsp. paratuberculosis K10  MAP_0123  AAS02440.1  Q745B0  301 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.93471488528255
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2419  WP_000118515.1  E8XEG5  nuoH  325 aa NADH-quinone oxidoreductase subunit NuoH 6.2e-14 ●●○○○ -1.93 -1.93384197809842
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1117  WP_002869043.1  A0A0H3P9D4  pepF  572 aa oligoendopeptidase F 0.032 ●●○○○ -1.93 -1.93351478714
Escherichia coli M12  CO715_19245  ATI07664.1  187 aa DNA endonuclease SmrA 2.1e-12 ●●○○○ -1.93 -1.93322345680123
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