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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0355  NP_232751.1  Q9KMJ3  208 aa hypothetical protein 0.0036 ○○○○○ 0.72 0.716596953565687
Escherichia coli M12  CO715_12595  ATI06471.1  329 aa serine/threonine dehydratase 2.0e-9 ○○○○○ 0.72 0.716789570173555
Porphyromonas gingivalis ATCC 33277  PGN_1628  WP_012458419.1  B2RLA2  319 aa glycosyltransferase 0.0022 ○○○○○ 0.72 0.716955903995212
Escherichia coli M12  CO715_11845  ATI06337.1  245 aa 1-acyl-sn-glycerol-3-phosphate acyltransferase 8.6e-10 ○○○○○ 0.72 0.716998216187804
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1232  AIK79855.1  160 aa periplasmic protein related to spheroblast formation 0.0032 ○○○○○ 0.72 0.717118443117777
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2043  AIK80649.1  339 aa bacterial regulatory, lacI family protein 1.2e-8 ○○○○○ 0.72 0.71729753663505
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0723  NP_230372.1  Q9KU07  ppk  701 aa polyphosphate kinase 0.0028 ○○○○○ 0.72 0.717377711647894
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1938  AIK80544.1  491 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ○○○○○ 0.72 0.717405862266492
Escherichia coli M12  CO715_14290  ATI08817.1  215 aa magnesium transporter ATPase 1.7e-6 ○○○○○ 0.72 0.71762415423055
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0955  NP_233339.1  Q9KKZ5  174 aa MarR family transcriptional regulator 0.008 ○○○○○ 0.72 0.717850498616581
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0873  NP_233259.1  Q9KL74  378 aa cytochrome d ubiquinol oxidase subunit II 0.0078 ○○○○○ 0.72 0.718139311497818
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0504  NP_232895.2  Q9K3D4  94 aa RelB protein 0.021 ○○○○○ 0.72 0.718375458594518
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2293  AIK80897.1  319 aa acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha <1e-323 ○○○○○ 0.72 0.718480606076372
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1551  NP_231191.1  Q9KRT5  ugpE  280 aa glycerol-3-phosphate ABC transporter permease 0.008 ○○○○○ 0.72 0.718601274716416
Escherichia coli M12  CO715_23745  ATI08455.1  346 aa hypothetical protein 0.0094 ○○○○○ 0.72 0.719084676330292
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2537  AIK81134.1  302 aa triphosphoribosyl-dephospho-CoA synthase CitG 2.2e-11 ○○○○○ 0.72 0.719452312489509
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0619  NP_233008.1  Q9KLX2  122 aa hypothetical protein 0.008 ○○○○○ 0.72 0.720041023018858
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2544  WP_000021076.1  E8XFQ0  cysA  365 aa sulfate/thiosulfate ABC transporter ATP-binding protein CysA 0.044 ○○○○○ 0.72 0.720167830842245
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4947  AIK83473.1  61 aa hypothetical protein 2.4e-11 ○○○○○ 0.72 0.720307345608444
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1319  AIK79942.1  206 aa 23S rRNA pseudouridine 2457 synthase 5.0e-6 ○○○○○ 0.72 0.72063737449257
Escherichia coli M12  CO715_02310  ATI04667.1  344 aa glycosyltransferase 4.3e-9 ○○○○○ 0.72 0.721171136472781
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0524  NP_232915.1  Q9KM64  320 aa hypothetical protein 0.012 ○○○○○ 0.72 0.72121715616062
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3632  AIK82186.1  406 aa major Facilitator Superfamily protein 0.0025 ○○○○○ 0.72 0.721225669017266
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4945  AIK83471.1  620 aa PTS system, beta-glucoside-specific IIABC component family protein 4.4e-16 ○○○○○ 0.72 0.721443345590414
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1902  AIK80508.1  412 aa amidohydrolase family protein 0.009 ○○○○○ 0.72 0.721929629039344
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4152  AIK82698.1  477 aa aryl-phospho-beta-D-glucosidase BglA <1e-323 ○○○○○ 0.72 0.721936928633476
Escherichia coli M12  CO715_12360  ATI06429.1  506 aa hypothetical protein 0.0051 ○○○○○ 0.72 0.723257596615269
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2630  NP_232258.1  Q9KNV0  578 aa fimbrial assembly protein 0.0056 ○○○○○ 0.72 0.72376285559576
Escherichia coli M12  CO715_15625  ATI07016.1  577 aa phosphoethanolamine transferase CptA 0.0063 ○○○○○ 0.72 0.723883534658016
Escherichia coli M12  CO715_01785  ATI04572.1  144 aa aminoalkylphosphonate N-acetyltransferase 0.011 ○○○○○ 0.72 0.723883534658016
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3103  AIK81684.1  377 aa thiazole biosynthesis protein ThiH <1e-323 ○○○○○ 0.72 0.72402065473187
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2217  AIK80822.1  401 aa exonuclease SbcCD, D subunit <1e-323 ○○○○○ 0.72 0.724277651534465
Escherichia coli M12  CO715_00945  ATI04424.1  415 aa tryptophan permease 6.2e-5 ○○○○○ 0.72 0.724300826686514
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2094  AIK80699.1  624 aa htpG <1e-323 ○○○○○ 0.72 0.724491891092248
Escherichia coli M12  CO715_15050  ATI06915.1  78 aa hypothetical protein 2.1e-5 ○○○○○ 0.73 0.725135410743509
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2628  AIK81222.1  279 aa PTS system mannose/fructose/sorbose IID component family protein <1e-323 ○○○○○ 0.73 0.725399741269234
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0081  NP_229740.1  Q9KVQ8  303 aa hypothetical protein 0.034 ○○○○○ 0.73 0.725826328077786
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0218  NP_232617.1  Q9KMV0  418 aa thermolabile hemolysin 0.0088 ○○○○○ 0.73 0.726968096726123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4328  AIK82873.1  211 aa precorrin-8X methylmutase family protein 4.4e-10 ○○○○○ 0.73 0.727356129208189
Escherichia coli M12  CO715_17080  ATI07278.1  330 aa RNA polymerase sigma factor RpoS 0.018 ○○○○○ 0.73 0.727430516900247
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4311  AIK82856.1  91 aa carbon dioxide concentrating mechanism protein CcmL 1.9e-13 ○○○○○ 0.73 0.727783950216947
Escherichia coli M12  CO715_01705  ATI04558.1  742 aa clamp-binding protein CrfC 3.1e-6 ○○○○○ 0.73 0.727847808928744
Escherichia coli M12  CO715_03910  ATI04960.1  540 aa phosphoenolpyruvate carboxykinase (ATP) 0.00016 ○○○○○ 0.73 0.727847808928744
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3306  AIK81867.1  193 aa molybdopterin-guanine dinucleotide biosynthesis protein A <1e-323 ○○○○○ 0.73 0.728027385841537
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4615  AIK83149.1  282 aa helix-turn-helix domain, rpiR family protein 0.0026 ○○○○○ 0.73 0.728130578756772
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4111  AIK82657.1  340 aa rieske [2Fe-2S] domain protein 6.0e-11 ○○○○○ 0.73 0.728159048608943
Escherichia coli M12  CO715_00665  ATI04375.1  150 aa hypothetical protein 0.0046 ○○○○○ 0.73 0.728473746971491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2253  AIK80858.1  349 aa branched-chain amino-acid ABC transport system permease protein 1.0e-10 ○○○○○ 0.73 0.728771143126796
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0217  NP_232616.1  Q9KMV1  359 aa diguanylate cyclase 0.0051 ○○○○○ 0.73 0.729071670743983
Escherichia coli M12  CO715_14875  ATI06883.1  528 aa propionate catabolism operon regulatory protein PrpR 2.0e-6 ○○○○○ 0.73 0.729725623056984
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2381  WP_000667146.1  E8XEC7  glpB  419 aa glycerol-3-phosphate dehydrogenase subunit GlpB 0.035 ○○○○○ 0.73 0.730245699603038
Acinetobacter baumannii ATCC 17978  A1S_1841  ABO12268.2  264 aa hypothetical protein 0.034 ○○○○○ 0.73 0.730299203250871
Escherichia coli M12  CO715_16640  ATI07201.1  816 aa fimbrial biogenesis outer membrane usher protein 3.0e-34 ○○○○○ 0.73 0.730351561099731
Escherichia coli M12  CO715_23105  ATI08901.1  326 aa 9-O-acetyl-N-acetylneuraminic acid deacetylase 1.1e-10 ○○○○○ 0.73 0.730351561099731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2004  AIK80610.1  360 aa hypothetical protein <1e-323 ○○○○○ 0.73 0.731618568862866
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1660  AIK80280.1  413 aa lacY lactose MFS transporter <1e-323 ○○○○○ 0.73 0.731701025444135
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0189  NP_232589.1  Q9KMX7  334 aa response regulator 0.0033 ○○○○○ 0.73 0.73179062394055
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1578  AIK80198.1  231 aa aqpZ - water MIP channel <1e-323 ○○○○○ 0.73 0.732415221039323
Escherichia coli M12  CO715_21885  ATI08147.1  1025 aa multidrug resistance protein MdtC 0.042 ○○○○○ 0.73 0.733063959284966
Acinetobacter baumannii ATCC 17978  A1S_2431  ABO12849.2  309 aa putative transcriptional regulator 0.036 ○○○○○ 0.73 0.733116844355689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3066  AIK81651.1  315 aa sorbitol operon regulator <1e-323 ○○○○○ 0.73 0.733708234626957
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1822  NP_231456.1  Q9KR25  621 aa PTS system fructose-specific transporter subunit IIABC 0.00027 ○○○○○ 0.73 0.733878491273474
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0914  NP_230561.1  Q9KTI8  1036 aa multidrug resistance protein 0.044 ○○○○○ 0.73 0.733935550746876
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4165  AIK82711.1  184 aa isopentenyl-diphosphate delta-isomerase 7.3e-13 ○○○○○ 0.73 0.734027827017388
Escherichia coli M12  CO715_01910  ATI04594.1  430 aa hypothetical protein 0.022 ○○○○○ 0.73 0.734315835370459
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2337  NP_231968.1  Q9KPM9  335 aa LacI family transcription regulator 0.015 ○○○○○ 0.74 0.735446132370066
Escherichia coli M12  CO715_15610  ATI07013.1  292 aa [formate-C-acetyltransferase]-activating enzyme 0.0028 ○○○○○ 0.74 0.736402295512948
Escherichia coli M12  CO715_00540  ATI04354.1  145 aa hypothetical protein 0.013 ○○○○○ 0.74 0.736402295512948
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1063  NP_230708.1  Q9KT42  286 aa acyl-CoA thioesterase II 0.00058 ○○○○○ 0.74 0.736496478831865
Escherichia coli M12  CO715_21400  ATI08057.1  376 aa multiphosphoryl transfer protein 1.4e-23 ○○○○○ 0.74 0.736610941527197
Escherichia coli M12  CO715_02175  ATI04643.1  268 aa NAD(P)-dependent oxidoreductase 0.00044 ○○○○○ 0.74 0.736610941527197
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1636  NP_231273.2  Q9KRK4  594 aa helicase-like protein 1.1e-5 ○○○○○ 0.74 0.736681228764229
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0100  NP_229759.1  Q9KVP1  glpE  106 aa thiosulfate sulfurtransferase 0.0035 ○○○○○ 0.74 0.736983084757467
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4791  WP_000942363.1  E8XDB9  gpmB  215 aa phosphoglycerate mutase GpmB 0.039 ○○○○○ 0.74 0.737391525230806
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0815  WP_001115209.1  E8XBQ3  hutU  561 aa urocanate hydratase 0.032 ○○○○○ 0.74 0.737687877370298
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1445  NP_231088.1  Q9KS16  572 aa sensor histidine kinase/response regulator 0.045 ○○○○○ 0.74 0.737908356494703
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0178  NP_229835.1  Q9KVG8  355 aa patatin-like protein 0.0016 ○○○○○ 0.74 0.738200782922374
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1442  AIK80063.1  266 aa pyrimidine utilization protein D 5.5e-5 ○○○○○ 0.74 0.738778801242853
Escherichia coli M12  CO715_20430  ATI07882.1  360 aa lac repressor 0.048 ○○○○○ 0.74 0.739531985726681
Escherichia coli M12  CO715_04975  ATI05142.1  403 aa glycosyltransferase WbuB 3.7e-8 ○○○○○ 0.74 0.73974063174093
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4832  AIK83359.1  585 aa citrate transporter family protein <1e-323 ○○○○○ 0.74 0.740239189140827
Escherichia coli M12  CO715_09010  ATI05844.1  257 aa molybdate ABC transporter substrate-binding protein 0.023 ○○○○○ 0.74 0.740366569783676
Escherichia coli M12  CO715_08560  ATI05761.1  94 aa hypothetical protein 0.028 ○○○○○ 0.74 0.740575215797925
Escherichia coli M12  CO715_13110  ATI06563.1  154 aa YhcH/YjgK/YiaL family protein 0.00021 ○○○○○ 0.74 0.740992507826423
Escherichia coli M12  CO715_24745  ATI08633.1  476 aa hypothetical protein 0.00011 ○○○○○ 0.74 0.741827091883418
Acinetobacter baumannii ATCC 17978  A1S_1490  ABO11918.2  297 aa glutamate/aspartate transport protein 0.042 ○○○○○ 0.74 0.742010347309826
Acinetobacter baumannii ATCC 17978  A1S_2814  ABO13220.2  120 aa twitching motility protein 0.045 ○○○○○ 0.74 0.742011174527329
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2220  NP_231851.1  Q9KPZ2  298 aa hypothetical protein 5.0e-5 ○○○○○ 0.74 0.742873714875819
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0623  NP_230272.1  Q9KUA0  rsmC  340 aa 16S rRNA methyltransferase 0.043 ○○○○○ 0.74 0.743060414796332
Escherichia coli M12  CO715_20550  ATI07904.1  270 aa pyrimidine utilization protein D 0.002 ○○○○○ 0.74 0.743078967968911
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1388  NP_231032.1  Q9KS71  lplA  338 aa lipoate-protein ligase A 0.012 ○○○○○ 0.74 0.743138162336742
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1752  AIK80372.1  89 aa hypothetical protein 0.024 ○○○○○ 0.74 0.744266994458459
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1016  AIK79639.1  397 aa astC <1e-323 ○○○○○ 0.74 0.744292130447572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1638  AIK80258.1  673 aa bacteriophage replication gene A family protein <1e-323 ○○○○○ 0.74 0.744481668672601
Acinetobacter baumannii ATCC 17978  A1S_1823  ABO12250.2  191 aa Transcriptional Regulator TetR family 0.022 ○○○○○ 0.74 0.744681379323148
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0163  NP_232563.1  Q9KN03  70 aa hypothetical protein 4.1e-5 ○○○○○ 0.74 0.744779105576796
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1927  AIK80533.1  413 aa entS MFS transporter 8.7e-10 ○○○○○ 0.75 0.74541428397995
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2759  AIK81349.1  436 aa phage integrase family protein 0.00017 ○○○○○ 0.75 0.745473588700525
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1721  NP_231357.1  Q9KRC1  purR  336 aa LacI family transcription regulator 0.0091 ○○○○○ 0.75 0.745689541121923
Escherichia coli M12  CO715_15275  ATI06955.1  604 aa hypothetical protein 4.6e-8 ○○○○○ 0.75 0.746000012168395
Retrieved entries 33,401–33,500 out of 36,363 total in 1503.1 ms (Link to these results)