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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3189  AIK81757.1  361 aa UDP-N-acetylglucosamine 2-epimerase 0.00067 ●○○○○ -0.34 -0.339761792950885
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3154  AIK81726.1  330 aa alpha/beta hydrolase fold family protein 3.8e-10 ●○○○○ -0.34 -0.338342069345861
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2747  AIK81337.1  370 aa radical SAM superfamily protein 5.6e-5 ●○○○○ -0.34 -0.337979473784822
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3012  AIK81597.1  379 aa bacterial extracellular solute-binding family protein <1e-323 ●○○○○ -0.34 -0.336282040189462
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3619  AIK82174.1  314 aa nickel ABC transporter, permease subunit NikB <1e-323 ●○○○○ -0.33 -0.334350044959139
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3195  AIK81763.1  499 aa ppx/GppA phosphatase family protein <1e-323 ●○○○○ -0.33 -0.333587045126559
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2834  AIK81423.1  446 aa modulator of DNA gyrase family protein 2.2e-16 ●○○○○ -0.33 -0.333140428877491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4669  AIK83203.1  235 aa P-type conjugative transfer protein TrbJ 1.6e-7 ●○○○○ -0.33 -0.3308337923127
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3458  AIK82014.1  283 aa glpF - glycerol MIP channel 5.6e-16 ●○○○○ -0.33 -0.330229371293249
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3194  AIK81762.1  421 aa ATP-dependent RNA helicase <1e-323 ●○○○○ -0.33 -0.328917553633569
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2011  AIK80617.1  80 aa hypothetical protein 2.5e-6 ●○○○○ -0.33 -0.328166802130345
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4366  AIK82909.1  465 aa pyridine nucleotide-disulfide oxidoreductase family protein 0.014 ●○○○○ -0.33 -0.328096697143275
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3971  AIK82519.1  473 aa dihydroxyacetone kinase, phosphotransfer subunit 0.045 ●○○○○ -0.33 -0.32743966911862
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2114  AIK80718.1  232 aa acetyltransferase domain protein <1e-323 ●○○○○ -0.33 -0.327400641271693
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2504  AIK81101.1  40 aa hypothetical protein 0.0021 ●○○○○ -0.33 -0.326847597430633
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4299  AIK82844.1  442 aa amino-acid N-acetyltransferase 3.7e-6 ●○○○○ -0.33 -0.325731523877623
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1918  AIK80525.1  65 aa hypothetical protein <1e-323 ●○○○○ -0.33 -0.325288914569615
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4835  AIK83362.1  308 aa lrhA transcriptional repressor LrhA transcriptional dual regulator 1.1e-5 ●○○○○ -0.32 -0.324111083869334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2738  AIK81328.1  1213 aa putative atpase involved in dna repair <1e-323 ●○○○○ -0.32 -0.323690123338647
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3611  AIK82166.1  73 aa universal stress B family protein <1e-323 ●○○○○ -0.32 -0.323563221363935
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3531  AIK82087.1  613 aa selenocysteine-specific translation elongation factor 1.7e-9 ●○○○○ -0.32 -0.323050462795281
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2221  AIK80826.1  94 aa hypothetical protein 0.0034 ●○○○○ -0.32 -0.321966549907868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2333  AIK80937.1  151 aa lysE type translocator family protein 9.0e-5 ●○○○○ -0.32 -0.320790763263803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3135  AIK81707.1  729 aa fatty oxidation complex, alpha subunit FadB 0.0012 ●○○○○ -0.32 -0.320472197742692
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4032  AIK82579.1  193 aa flavodoxin-like fold family protein 0.00099 ●○○○○ -0.32 -0.319172427268432
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4497  AIK83035.1  518 aa glutamate--cysteine ligase 3.4e-12 ●○○○○ -0.32 -0.317656890499505
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2856  AIK81444.1  185 aa hypothetical protein 3.0e-9 ●○○○○ -0.32 -0.317052531834923
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3379  AIK81936.1  540 aa PTS system, alpha-glucoside-specific IIBC component domain protein <1e-323 ●○○○○ -0.32 -0.316865074300291
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2938  AIK81524.1  598 aa fused thiol:disulfide interchange protein: membrane electron transporter: activator of DsbC 2.8e-10 ●○○○○ -0.31 -0.314670386668882
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2653  AIK81247.1  285 aa 3,4-dihydroxyphenylacetate 2,3-dioxygenase <1e-323 ●○○○○ -0.31 -0.314651115582891
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2739  AIK81329.1  1228 aa eco57I restriction-modification methylase familyprotein <1e-323 ●○○○○ -0.31 -0.314606230252921
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3794  AIK82349.1  50 aa hypothetical protein 9.0e-6 ●○○○○ -0.31 -0.313383547766035
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3645  AIK82200.1  421 aa 4-aminobutyrate transaminase 1.2e-9 ●○○○○ -0.31 -0.311603291885969
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2646  AIK81240.1  338 aa dpkA 1.1e-12 ●○○○○ -0.31 -0.311270380974611
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2960  AIK81545.1  471 aa sugar (Glycoside-Pentoside-Hexuronide) transporter domain protein <1e-323 ●○○○○ -0.31 -0.309803170225929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2836  AIK81425.1  402 aa putative thioredoxin-like protein 1.4e-10 ●○○○○ -0.31 -0.308412411231488
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4145  AIK82691.1  247 aa putative NAD(P)-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain 1.7e-12 ●○○○○ -0.31 -0.30802263902877
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4101  AIK82647.1  232 aa extracellular deoxyribonuclease 4.8e-13 ●○○○○ -0.31 -0.307277148642546
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1832  AIK80445.1  266 aa glucosamine-6-phosphate deaminase 0.0005 ●○○○○ -0.3 -0.304382629232573
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3648  AIK82203.1  127 aa hypothetical protein 8.4e-12 ●○○○○ -0.3 -0.303592395365093
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4042  AIK82589.1  275 aa 2,5-diketo-D-gluconic acid reductase A 0.00087 ●○○○○ -0.3 -0.30277276417837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4958  AIK83484.1  245 aa binding-protein-dependent transport system innermembrane component family protein 0.00033 ●○○○○ -0.3 -0.29989873717491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4941  AIK83467.1  132 aa lrgA family protein 0.0019 ●○○○○ -0.3 -0.298914639646587
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2703  AIK81293.1  477 aa heavy metal sensor kinase family protein <1e-323 ●○○○○ -0.3 -0.298423242874373
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2899  AIK81488.1  503 aa putative carbohydrate kinase <1e-323 ●○○○○ -0.3 -0.298011576379226
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2490  AIK81087.1  574 aa acetolactate synthase, large subunit, biosynthetic type <1e-323 ●○○○○ -0.3 -0.297909934409701
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3523  AIK82079.1  551 aa lldP lactate transporter <1e-323 ●○○○○ -0.3 -0.297327126411976
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3673  AIK82228.1  728 aa 1,4-alpha-glucan branching enzyme <1e-323 ●○○○○ -0.3 -0.296157055612856
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3174  AIK81746.1  398 aa tetratricopeptide repeat family protein <1e-323 ●○○○○ -0.3 -0.295048639175677
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3636  AIK82191.1  208 aa yhhN-like family protein <1e-323 ●○○○○ -0.29 -0.293948168137815
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2589  AIK81186.1  215 aa bacterial virulence factor hemolysin family protein 7.3e-12 ●○○○○ -0.29 -0.293945380834143
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2846  AIK81435.1  114 aa AIG2-like family protein 1.3e-6 ●○○○○ -0.29 -0.293285601823746
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4717  AIK83251.1  229 aa cupin domain protein 0.036 ●○○○○ -0.29 -0.292407691706183
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2533  AIK81130.1  1074 aa carB 9.9e-5 ●○○○○ -0.29 -0.29192513884142
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3571  AIK82126.1  327 aa dppD <1e-323 ●○○○○ -0.29 -0.28965565728704
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3388  AIK81945.1  277 aa eamA-like transporter family protein 0.00034 ●○○○○ -0.29 -0.287987121622977
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2617  AIK81211.1  394 aa 4-hydroxybenzoate 3-monooxygenase 2.2e-16 ●○○○○ -0.29 -0.286515210261699
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3056  AIK81641.1  246 aa azlC family protein 4.4e-11 ●○○○○ -0.28 -0.283429711087017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2865  AIK81454.1  224 aa opacity-associated A N-terminal motif family protein 0.0017 ●○○○○ -0.28 -0.282774170960001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2838  AIK81427.1  445 aa L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase <1e-323 ●○○○○ -0.28 -0.282677712207012
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3871  AIK82421.1  325 aa yrbG CaCA transporter <1e-323 ●○○○○ -0.28 -0.281517099006905
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1969  AIK80575.1  422 aa amidase, hydantoinase/carbamoylase family protein 4.5e-8 ●○○○○ -0.28 -0.279418312064731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3752  AIK82308.1  161 aa type IV leader peptidase family protein 3.6e-6 ●○○○○ -0.28 -0.278589228331874
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2814  AIK81403.1  439 aa PTS system, cellobiose-specific IIC component 7.8e-16 ●○○○○ -0.28 -0.276279490217184
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3432  AIK81988.1  497 aa H+ antiporter-2 family protein <1e-323 ●○○○○ -0.28 -0.276124907071236
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3850  AIK82400.1  164 aa stringent starvation B family protein 0.00033 ●○○○○ -0.28 -0.276105549526763
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2619  AIK81213.1  258 aa hypothetical protein 1.2e-6 ●○○○○ -0.28 -0.27532199135008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3399  AIK81956.1  119 aa hypothetical protein <1e-323 ●○○○○ -0.28 -0.275144127170017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3549  AIK82105.1  539 aa ABC transporter family protein 3.6e-14 ●○○○○ -0.27 -0.273651774228328
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3413  AIK81970.1  448 aa sugar (and other) transporter family protein 6.7e-8 ●○○○○ -0.27 -0.271953822678993
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4936  AIK83462.1  506 aa ABC transporter family protein <1e-323 ●○○○○ -0.27 -0.271366902361865
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3955  AIK82503.1  200 aa helix-turn-helix family protein 0.00019 ●○○○○ -0.27 -0.271113074418181
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3236  AIK81797.1  293 aa eamA-like transporter family protein <1e-323 ●○○○○ -0.27 -0.269664461540707
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2120  AIK80725.1  366 aa arabinogalactan endo-1,4-beta-galactosidase <1e-323 ●○○○○ -0.27 -0.269601667074621
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4787  AIK83314.1  440 aa 47 kDa outer membrane protein <1e-323 ●○○○○ -0.27 -0.268609534829842
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2861  AIK81450.1  323 aa eamA-like transporter family protein <1e-323 ●○○○○ -0.27 -0.268048854554371
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4667  AIK83201.1  396 aa phage integrase family protein 5.0e-7 ●○○○○ -0.27 -0.267629828273028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2102  AIK80707.1  303 aa hypothetical protein <1e-323 ●○○○○ -0.27 -0.267388971240569
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3685  AIK82240.1  697 aa 4-alpha-glucanotransferase <1e-323 ●○○○○ -0.26 -0.263476496881013
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4927  AIK83453.1  288 aa LYSR-type transcriptional regulator 0.001 ●○○○○ -0.26 -0.262838442642123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3598  AIK82153.1  299 aa putative transcriptional regulator LYSR-type <1e-323 ●○○○○ -0.26 -0.262104619084652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4230  AIK82775.1  870 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.26 -0.261770991495134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2424  AIK81021.1  293 aa glutamyl-queuosine tRNA(Asp) synthetase <1e-323 ●○○○○ -0.26 -0.259229158814532
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1899  AIK80505.1  202 aa methylthioribulose-1-phosphate dehydratase 1.5e-8 ●○○○○ -0.26 -0.257379731260237
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2052  AIK80658.1  425 aa adiC 0.0018 ●○○○○ -0.26 -0.257110653948169
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2819  AIK81408.1  154 aa anaerobic ribonucleoside-triphosphate reductase activating protein 1.8e-6 ●○○○○ -0.26 -0.256867498594394
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1153  AIK79776.1  381 aa amidohydrolase family protein 0.033 ●○○○○ -0.26 -0.256712997238804
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3384  AIK81941.1  442 aa D-serine ammonia-lyase <1e-323 ●○○○○ -0.26 -0.256524945030451
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1700  AIK80320.1  444 aa DEAD-box-containing ATP-dependent RNA helicase family member 0.00076 ●○○○○ -0.26 -0.256406520560127
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4358  AIK82901.1  591 aa L-fucose isomerase <1e-323 ●○○○○ -0.26 -0.2557319645789
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3151  AIK81723.1  754 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase <1e-323 ●○○○○ -0.26 -0.255248192281561
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1907  AIK80513.1  342 aa S-methyl-5-thioribose-1-phosphate isomerase 0.034 ●○○○○ -0.26 -0.255245622841332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2632  AIK81226.1  921 aa AAA domain family protein <1e-323 ●○○○○ -0.25 -0.254759012967904
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4573  AIK83111.1  456 aa pepSY-associated TM helix family protein 6.8e-12 ●○○○○ -0.25 -0.254066238762764
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2026  AIK80632.1  372 aa periplasmic binding family protein 0.018 ●○○○○ -0.25 -0.25377619102056
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2700  AIK81290.1  373 aa cupin superfamily protein 9.4e-5 ●○○○○ -0.25 -0.252577706602095
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3872  AIK82422.1  270 aa mlaF 0.001 ●○○○○ -0.25 -0.251931714519342
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4750  AIK83284.1  323 aa cysteine synthase A 1.3e-14 ●○○○○ -0.25 -0.25053027819887
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1256  AIK79879.1  339 aa L-asparaginase I 0.0039 ●○○○○ -0.25 -0.25033036439997
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2842  AIK81431.1  500 aa ytfR 7.8e-5 ●○○○○ -0.25 -0.248671767224754
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