Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1138  NP_230783.1  Q9KSW8  hisF  257 aa imidazole glycerol phosphate synthase subunit HisF 0.028 ○○○○○ 0.37 0.365922004060293
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3274  AIK81835.1  707 aa alpha-galactosidase <1e-323 ○○○○○ 0.37 0.366507798023279
Escherichia coli M12  CO715_16525  ATI07179.1  504 aa L-carnitine/gamma-butyrobetaine antiporter 0.003 ○○○○○ 0.37 0.366681558263966
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2830  AIK81419.1  120 aa glycine-rich SFCGS family protein 0.00054 ○○○○○ 0.37 0.366718928865548
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4186  AIK82731.1  270 aa binding-protein-dependent transport system innermembrane component family protein 1.4e-6 ○○○○○ 0.37 0.366928629454702
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1977  AIK80583.1  239 aa hypothetical protein 6.2e-6 ○○○○○ 0.37 0.366999631864478
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2549  AIK81146.1  309 aa bacterial regulatory helix-turn-helix, lysR family protein 0.0045 ○○○○○ 0.37 0.367095425038036
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3949  AIK82497.1  495 aa D-altronate dehydratase <1e-323 ○○○○○ 0.37 0.367296343583175
Escherichia coli M12  CO715_04595  ATI08724.1  223 aa DNA-binding response regulator 0.011 ○○○○○ 0.37 0.367307496306712
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3089  AIK81670.1  464 aa his Kinase A domain protein 0.035 ○○○○○ 0.37 0.367874104055017
Escherichia coli M12  CO715_09215  ATI05875.1  481 aa methylaspartate mutase subunit E 0.033 ○○○○○ 0.37 0.368142080363708
Escherichia coli M12  CO715_02170  ATI04642.1  315 aa Cro/Cl family transcriptional regulator 0.032 ○○○○○ 0.37 0.368768018406454
Escherichia coli M12  CO715_23595  ATI08432.1  484 aa allantoin permease 7.2e-13 ○○○○○ 0.37 0.369393956449201
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2641  NP_232269.1  Q9KNT9  argH  458 aa argininosuccinate lyase 0.0001 ○○○○○ 0.37 0.369488404144155
Escherichia coli M12  CO715_21335  ATI08044.1  114 aa hypothetical protein 0.027 ○○○○○ 0.37 0.36960260246345
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2741  AIK81331.1  694 aa lon protease (S16) C-terminal proteolytic domainprotein 2.2e-16 ○○○○○ 0.37 0.369983590400748
Escherichia coli M12  CO715_23860  ATI08477.1  728 aa 1,4-alpha-glucan-branching protein 0.00039 ○○○○○ 0.37 0.370019894491947
Porphyromonas gingivalis ATCC 33277  PGN_0062  WP_012457208.1  B2RGT6  traK  207 aa conjugative transposon protein TraK 1.3e-14 ○○○○○ 0.37 0.370133824344833
Porphyromonas gingivalis ATCC 33277  PGN_1632  WP_012458423.1  B2RLA6  331 aa hypothetical protein 1.4e-8 ○○○○○ 0.37 0.370133824344833
Escherichia coli M12  CO715_14495  ATI06812.1  283 aa fructose-1,6-bisphosphate aldolase 0.023 ○○○○○ 0.37 0.371063124563192
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4543  AIK83081.1  242 aa class II Aldolase and Adducin N-terminal domain protein 3.6e-11 ○○○○○ 0.37 0.371183558967388
Escherichia coli M12  CO715_18250  ATI07488.1  243 aa hypothetical protein 5.0e-6 ○○○○○ 0.37 0.372732292677183
Escherichia coli M12  CO715_12535  ATI06459.1  121 aa DUF805 domain-containing protein 1.2e-6 ○○○○○ 0.37 0.373775522748427
Escherichia coli M12  CO715_13595  ATI06648.1  187 aa thermosensitive gluconokinase 0.00014 ○○○○○ 0.37 0.373775522748427
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3415  AIK81971.1  420 aa aromatic-ring-opening dioxygenase LigAB, LigA subunit <1e-323 ○○○○○ 0.37 0.374295455290975
Escherichia coli M12  CO715_01805  ATI04576.1  661 aa alkyl/aryl-sulfatase 0.0002 ○○○○○ 0.37 0.374401460791173
Escherichia coli M12  CO715_00345  ATI04320.1  327 aa sugar ABC transporter substrate-binding protein 0.00048 ○○○○○ 0.38 0.375444690862418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4771  AIK83299.1  318 aa putative oxidoreductase 4.0e-7 ○○○○○ 0.38 0.375577703110605
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1871  AIK80477.1  298 aa bacterial regulatory helix-turn-helix, lysR family protein 8.4e-7 ○○○○○ 0.38 0.375795991604271
Escherichia coli M12  CO715_00625  ATI08695.1  563 aa kdo(2)-lipid A phosphoethanolamine 7''-transferase 0.01 ○○○○○ 0.38 0.375861982890915
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1635  AIK80255.1  592 aa ATPase subunit of terminase family protein 9.7e-9 ○○○○○ 0.38 0.376058978625533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2131  AIK80736.1  475 aa bacterial regulatory, gntR family protein 0.0029 ○○○○○ 0.38 0.376366155770197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2942  AIK81527.1  158 aa PAAR motif family protein <1e-323 ○○○○○ 0.38 0.377039169840211
Escherichia coli M12  CO715_20320  ATI07862.1  968 aa outer membrane autotransporter barrel domain-containing protein 0.00017 ○○○○○ 0.38 0.377322504990657
Escherichia coli M12  CO715_08020  ATI05662.1  555 aa acyl-CoA synthetase FdrA 0.00024 ○○○○○ 0.38 0.378574381076151
Escherichia coli M12  CO715_23955  ATI08494.1  338 aa RNA 3'-phosphate cyclase 1.0e-5 ○○○○○ 0.38 0.380034903175893
Escherichia coli M12  CO715_21130  ATI08010.1  358 aa glycerophosphodiester phosphodiesterase 0.02 ○○○○○ 0.38 0.380243549190142
Escherichia coli M12  CO715_08920  ATI05826.1  302 aa hypothetical protein 0.0086 ○○○○○ 0.38 0.38045219520439
Escherichia coli M12  CO715_23865  ATI08478.1  657 aa glycogen debranching enzyme 0.016 ○○○○○ 0.38 0.381495425275635
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4566  AIK83104.1  263 aa cytochrome C assembly family protein <1e-323 ○○○○○ 0.38 0.381595942854931
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1068  NP_230713.1  Q9KT37  113 aa ArsR family transcriptional regulator 0.033 ○○○○○ 0.38 0.382299936237016
Porphyromonas gingivalis ATCC 33277  PGN_0233  WP_012457352.1  B2RHA7  232 aa glycosyltransferase 3.1e-7 ○○○○○ 0.38 0.382574995333284
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2676  AIK81271.1  354 aa hypothetical protein <1e-323 ○○○○○ 0.38 0.383864426913308
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5090  AIK83616.1  912 aa type IV secretory pathway, VirB3-like family protein <1e-323 ○○○○○ 0.38 0.384392695606719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1726  AIK80346.1  673 aa excinuclease ABC subunit B 9.5e-5 ○○○○○ 0.38 0.384715534524211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4965  AIK83491.1  153 aa acetyltransferase family protein 1.2e-13 ○○○○○ 0.38 0.384844523075785
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1955  AIK80561.1  522 aa bacterial extracellular solute-binding, 5 Middlefamily protein 4.7e-13 ○○○○○ 0.39 0.38566218441777
Porphyromonas gingivalis ATCC 33277  PGN_1111  WP_004585540.1  B2RJT5  fhs  555 aa formate--tetrahydrofolate ligase 1.6e-5 ○○○○○ 0.39 0.385863233435664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2264  AIK80869.1  824 aa putative enzyme <1e-323 ○○○○○ 0.39 0.386514550527461
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2505  AIK81102.1  551 aa sgrR transcriptional regulator 2.5e-6 ○○○○○ 0.39 0.388293462886575
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2104  AIK80709.1  216 aa acrR transcriptional regulator AcrR transcriptional repressor <1e-323 ○○○○○ 0.39 0.389336368737818
Escherichia coli M12  CO715_03205  ATI04831.1  564 aa oxalyl-CoA decarboxylase 0.00013 ○○○○○ 0.39 0.38963261983134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3093  AIK81674.1  196 aa hypothetical protein 1.1e-16 ○○○○○ 0.39 0.389728500605813
Escherichia coli M12  CO715_18350  ATI07506.1  328 aa hypothetical protein 0.0031 ○○○○○ 0.39 0.389841265845589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1763  AIK80383.1  338 aa UDP-glucose 4-epimerase 0.0015 ○○○○○ 0.39 0.390208168243534
Escherichia coli M12  CO715_09770  ATI05971.1  186 aa phospholipid:lipid A palmitoyltransferase 0.0083 ○○○○○ 0.39 0.390467203888336
Escherichia coli M12  CO715_17585  ATI07371.1  472 aa arabinose-proton symporter 0.003 ○○○○○ 0.39 0.390884495916833
Porphyromonas gingivalis ATCC 33277  PGN_0383  WP_012457466.1  B2RHQ7  303 aa transporter 0.00055 ○○○○○ 0.39 0.390953168414665
Escherichia coli M12  CO715_17755  ATI07401.1  155 aa type III secretion protein 0.014 ○○○○○ 0.39 0.391301787945331
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1069  NP_230714.1  Q9KT36  333 aa glyceraldehyde-3-phosphate dehydrogenase 0.00084 ○○○○○ 0.39 0.393145987167261
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3280  AIK81841.1  278 aa formate dehydrogenase family accessory protein FdhD <1e-323 ○○○○○ 0.39 0.393837924002787
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4117  AIK82663.1  158 aa cupin domain protein 1.3e-11 ○○○○○ 0.39 0.394381124290486
Escherichia coli M12  CO715_21175  ATI08017.1  1237 aa AIDA-I family autotransporter YfaL 0.00011 ○○○○○ 0.39 0.394431478159064
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1939  AIK80545.1  362 aa branched-chain amino acid transport system / permease component family protein <1e-323 ○○○○○ 0.39 0.394731302972175
Escherichia coli M12  CO715_23205  ATI08376.1  655 aa YjhG/YagF family D-xylonate dehydratase 9.2e-5 ○○○○○ 0.4 0.395683354244557
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0392  NP_230046.1  Q9KUW7  372 aa class V aminotransferase 0.047 ○○○○○ 0.4 0.396995554962481
Escherichia coli M12  CO715_16430  ATI07160.1  783 aa DNA polymerase II 0.0055 ○○○○○ 0.4 0.397769814387046
Escherichia coli M12  CO715_00515  ATI04349.1  513 aa D-xylose ABC transporter ATP-binding protein 2.3e-12 ○○○○○ 0.4 0.398187106415544
Porphyromonas gingivalis ATCC 33277  PGN_1963  WP_012458646.1  B2RM86  431 aa hypothetical protein 6.8e-6 ○○○○○ 0.4 0.398303195660559
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4966  AIK83492.1  105 aa hypothetical protein 1.1e-7 ○○○○○ 0.4 0.399547636140745
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1228  AIK79851.1  106 aa lichenan-specific phosphotransferase enzyme IIB component 0.001 ○○○○○ 0.4 0.400091961630816
Escherichia coli M12  CO715_01800  ATI04575.1  105 aa ribose-5-phosphate isomerase 0.016 ○○○○○ 0.4 0.400899504600779
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2508  AIK81106.1  255 aa inner membrane protein yabI <1e-323 ○○○○○ 0.4 0.401391059610539
Porphyromonas gingivalis ATCC 33277  PGN_0690  WP_021678821.1  B2RIL4  183 aa HD domain-containing protein <1e-323 ○○○○○ 0.4 0.401628144289643
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5152  AIK83673.1  44 aa hypothetical protein 0.0022 ○○○○○ 0.4 0.403330957465232
Escherichia coli M12  CO715_06150  ATI05336.1  1806 aa outer membrane autotransporter barrel domain-containing protein 0.016 ○○○○○ 0.4 0.403403256771765
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1439  AIK80060.1  363 aa pyrimidine utilization protein A 0.0067 ○○○○○ 0.4 0.403767287612994
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2072  AIK80677.1  381 aa putative outer membrane protein <1e-323 ○○○○○ 0.4 0.404033118581861
Escherichia coli M12  CO715_12705  ATI06490.1  384 aa AgaS family sugar isomerase 0.012 ○○○○○ 0.4 0.404237840828761
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4691  AIK83226.1  307 aa hypothetical protein 0.00062 ○○○○○ 0.41 0.405549803293728
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2574  AIK81171.1  228 aa RNA methyltransferase, TrmH, group 1 family protein <1e-323 ○○○○○ 0.41 0.406495508334592
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4310  AIK82855.1  338 aa cob(I)alamin adenosyltransferase 2.9e-9 ○○○○○ 0.41 0.406540806393615
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4688  AIK83222.1  477 aa glycosyl hydrolase 1 family protein <1e-323 ○○○○○ 0.41 0.407548173109367
Porphyromonas gingivalis ATCC 33277  PGN_1200  WP_010956212.1  B2RK24  434 aa replication-associated recombination protein A 5.0e-15 ○○○○○ 0.41 0.40763504437895
Escherichia coli M12  CO715_03800  ATI04941.1  200 aa histidine phosphatase family protein 2.7e-8 ○○○○○ 0.41 0.408410761113738
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1094  AIK79717.1  393 aa hypothetical protein 8.5e-6 ○○○○○ 0.41 0.408626946816684
Escherichia coli M12  CO715_18120  ATI07464.1  246 aa oxidative stress defense protein 0.033 ○○○○○ 0.41 0.409036699156484
Escherichia coli M12  CO715_03010  ATI04798.1  575 aa phosphoenolpyruvate--protein phosphotransferase 0.023 ○○○○○ 0.41 0.409245345170733
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2724  AIK81314.1  559 aa beta-xylosidase <1e-323 ○○○○○ 0.41 0.409638379362814
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3349  AIK81906.1  239 aa glucosamine-6-phosphate isomerases/6-phosphogluconolactonase family protein 1.1e-13 ○○○○○ 0.41 0.409906791583931
Escherichia coli M12  CO715_18360  ATI07508.1  433 aa TRAP transporter permease DctM 0.0012 ○○○○○ 0.41 0.410079929227729
Escherichia coli M12  CO715_01945  ATI04601.1  527 aa cyclic diguanylate phosphodiesterase 0.00043 ○○○○○ 0.41 0.410497221256227
Escherichia coli M12  CO715_23120  ATI08363.1  69 aa DNA helicase 0.023 ○○○○○ 0.41 0.411123159298973
Escherichia coli M12  CO715_12050  ATI06375.1  304 aa short-chain dehydrogenase 2.6e-6 ○○○○○ 0.41 0.411540451327471
Escherichia coli CFT073  c5423  AAN83843.1  A0A0H2VFF1  589 aa Putative restriction modification enzyme S subunit 9.8e-19 ○○○○○ 0.41 0.412299555646972
Escherichia coli M12  CO715_12075  ATI06380.1  350 aa glycolate oxidase subunit GlcE 0.045 ○○○○○ 0.41 0.412375035384466
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2464  AIK81061.1  347 aa guanosine monophosphate reductase 3.4e-13 ○○○○○ 0.41 0.413974259983443
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4779  AIK83307.1  378 aa sugar (and other) transporter family protein 1.2e-13 ○○○○○ 0.42 0.415257560609986
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2640  AIK81233.1  287 aa helix-turn-helix domain, rpiR family protein 0.00038 ○○○○○ 0.42 0.415817489806625
Escherichia coli M12  CO715_24695  ATI08625.1  551 aa L-lactate permease 0.0012 ○○○○○ 0.42 0.416339309655195
Retrieved entries 32,701–32,800 out of 36,363 total in 5.1 ms (Link to these results)