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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2768  AIK81357.1  489 aa sulfate transporter family protein 2.6e-15 ●○○○○ -0.86 -0.860589611123095
Escherichia coli M12  CO715_10115  ATI06028.1  177 aa lysozyme 5.9e-18 ●○○○○ -0.86 -0.85994835950509
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2000  AIK80606.1  340 aa xylose isomerase-like TIM barrel family protein 2.6e-6 ●○○○○ -0.86 -0.859915664410589
Escherichia coli M12  CO715_14670  ATI06845.1  221 aa VUT family protein 2.7e-31 ●○○○○ -0.86 -0.859322421462343
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2127  AIK80732.1  513 aa EAL domain protein <1e-323 ●○○○○ -0.86 -0.859095917950609
Porphyromonas gingivalis ATCC 33277  PGN_0718  WP_012457725.1  B2RIP2  783 aa FtsX-like permease family protein <1e-323 ●○○○○ -0.86 -0.859023101015382
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0603  NP_232992.1  Q9KLY8  339 aa ABC transporter substrate-binding protein 1.3e-6 ●○○○○ -0.86 -0.858317762488687
Acinetobacter baumannii ATCC 17978  A1S_2313  ABO12735.2  A3M741  queF  270 aa EsvE1 1.0e-7 ●○○○○ -0.86 -0.858286754724388
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0609  NP_230258.1  Q9KUB4  541 aa iron(III) ABC transporter permease 1.7e-8 ●○○○○ -0.86 -0.858036441004417
Escherichia coli M12  CO715_02895  ATI04776.1  295 aa ethanolamine ammonia-lyase light chain 9.1e-13 ●○○○○ -0.86 -0.856610023277108
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4119  AIK82665.1  264 aa putative short-chain dehydrogenase 0.00017 ●○○○○ -0.86 -0.856576530273263
Escherichia coli M12  CO715_08930  ATI05828.1  225 aa ATP-dependent dethiobiotin synthetase BioD 7.3e-8 ●○○○○ -0.85 -0.854940855163117
Acinetobacter baumannii ATCC 17978  A1S_0258  ABO10733.1  A3M1E0  argH  37 aa argininosuccinate lyase 0.0097 ●○○○○ -0.85 -0.854211130426638
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0087  NP_232488.1  Q9KN78  54 aa hypothetical protein 1.5e-5 ●○○○○ -0.85 -0.853628796189995
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4401  AIK82944.1  457 aa cysG <1e-323 ●○○○○ -0.85 -0.852681069347745
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0720  NP_230369.1  Q9KU10  433 aa phosphate regulon sensor protein 2.3e-7 ●○○○○ -0.85 -0.852514856764618
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1630  WP_001670738.1  E8XJU8  263 aa DeoR/GlpR transcriptional regulator 7.3e-5 ●○○○○ -0.85 -0.852215941975654
Escherichia coli M12  CO715_10195  ATI06038.1  341 aa hypothetical protein 4.7e-7 ●○○○○ -0.85 -0.852019810963633
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0605  NP_232994.1  Q9KLY6  465 aa 4-aminobutyrate aminotransferase 2.9e-7 ●○○○○ -0.85 -0.851966557896758
Acinetobacter baumannii ATCC 17978  A1S_3366  ABO13755.1  394 aa gamma-glutamate-cysteine ligase 2.2e-7 ●○○○○ -0.85 -0.850672096763414
Porphyromonas gingivalis ATCC 33277  PGN_0770  WP_012457766.1  B2RIU4  rnz  304 aa ribonuclease Z <1e-323 ●○○○○ -0.85 -0.849955187289735
Porphyromonas gingivalis ATCC 33277  PGN_1691  WP_012458462.1  B2RLG5  376 aa aminotransferase class V-fold PLP-dependent enzyme <1e-323 ●○○○○ -0.85 -0.849912569537593
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1020  NP_233404.1  Q9KKT0  306 aa LysR family transcriptional regulator 0.00099 ●○○○○ -0.85 -0.849673538515005
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4061  AIK82608.1  82 aa hypothetical protein 0.00091 ●○○○○ -0.85 -0.848932031202139
Escherichia coli M12  CO715_09350  ATI05898.1  310 aa hypothetical protein 0.023 ●○○○○ -0.85 -0.848681474735651
Acinetobacter baumannii ATCC 17978  A1S_2427  ABO12845.2  729 aa putative transporter 1.4e-7 ●○○○○ -0.85 -0.848667964704785
Escherichia coli M12  CO715_08835  ATI05810.1  454 aa ATP-dependent RNA helicase RhlE 1.4e-25 ●○○○○ -0.85 -0.848055536692905
Acinetobacter baumannii ATCC 17978  A1S_2682  ABO13095.2  A3M851  rlmE  216 aa cell division protein 0.0032 ●○○○○ -0.85 -0.847852690053193
Escherichia coli M12  CO715_21925  ATI08154.1  450 aa molecular chaperone 3.2e-29 ●○○○○ -0.85 -0.847220952635909
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1200  NP_230845.1  Q9KSQ6  403 aa serine protease 3.5e-6 ●○○○○ -0.85 -0.847142986766788
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4059  WP_000102338.1  E8XIK0  trkD  622 aa low affinity potassium transporter Kup 0.0033 ●○○○○ -0.85 -0.846467665489276
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4399  AIK82942.1  244 aa phosphoadenosine phosphosulfate reductase <1e-323 ●○○○○ -0.85 -0.845948232871937
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3394  AIK81951.1  500 aa histidine kinase-, DNA gyrase B-, and HSP90-likeATPase family protein 6.5e-14 ●○○○○ -0.85 -0.845600194943583
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0047  NP_232448.1  Q9KNB8  376 aa hypothetical protein 0.0018 ●○○○○ -0.85 -0.845336481831041
Acinetobacter baumannii ATCC 17978  A1S_0888  ABO11320.2  A3M326  argB  302 aa acetylglutamate kinase 1.4e-7 ●○○○○ -0.84 -0.844890378108718
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4460  AIK83004.1  102 aa toxin SymE, type I toxin-antitoxin system familyprotein 8.8e-13 ●○○○○ -0.84 -0.844846191943587
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2030  WP_000394196.1  E8XB20  umuD  139 aa translesion error-prone DNA polymerase V autoproteolytic subunit 2.0e-8 ●○○○○ -0.84 -0.844610927884034
Porphyromonas gingivalis ATCC 33277  PGN_1537  WP_012458355.1  B2RL11  366 aa efflux RND transporter periplasmic adaptor subunit <1e-323 ●○○○○ -0.84 -0.842974058056172
Escherichia coli M12  CO715_10375  ATI06067.1  273 aa serine protease 2.6e-28 ●○○○○ -0.84 -0.842839386336683
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2428  WP_000074540.1  E8XEY4  yfbQ  404 aa pyridoxal phosphate-dependent aminotransferase 0.00017 ●○○○○ -0.84 -0.84231883420618
Escherichia coli M12  CO715_09425  ATI05912.1  894 aa two-component system sensor histidine kinase KdbD 4.6e-14 ●○○○○ -0.84 -0.842004802279688
Acinetobacter baumannii ATCC 17978  A1S_2003  ABO12430.1  142 aa putative nitrate reductase 0.005 ●○○○○ -0.84 -0.841218512446843
Acinetobacter baumannii ATCC 17978  A1S_2474  ABO12892.2  363 aa major facilitator family transporter 3.8e-7 ●○○○○ -0.84 -0.841169121032999
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3196  AIK81764.1  308 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.84 -0.840733973519043
Porphyromonas gingivalis ATCC 33277  PGN_2016  WP_012458688.1  B2RMD9  139 aa hypothetical protein <1e-323 ●○○○○ -0.84 -0.840328151694636
Escherichia coli M12  CO715_17925  ATI07430.1  41 aa hypothetical protein 1.0e-5 ●○○○○ -0.84 -0.840126988151448
Acinetobacter baumannii ATCC 17978  A1S_3128  ABO13525.2  A3M9D1  astE  324 aa succinylglutamate desuccinylase 4.3e-5 ●○○○○ -0.84 -0.839908488743476
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2390  WP_001574701.1  E8XED6  yfaZ  215 aa membrane protein 9.2e-5 ●○○○○ -0.84 -0.839529226118645
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4391  WP_000368196.1  E8X8V9  581 aa tail protein 0.0063 ●○○○○ -0.84 -0.839289744134404
Porphyromonas gingivalis ATCC 33277  PGN_1681  WP_004584758.1  B2RLF5  223 aa ABC transporter ATP-binding protein 0.0076 ●○○○○ -0.84 -0.838925852388692
Escherichia coli M12  CO715_16750  ATI07221.1  319 aa class 1b ribonucleoside-diphosphate reductase subunit beta 6.7e-42 ●○○○○ -0.84 -0.838666466051706
Acinetobacter baumannii ATCC 17978  A1S_2912  ABO13317.2  A3M8S3  tgt  377 aa queuine tRNA-ribosyltransferase 2.6e-7 ●○○○○ -0.84 -0.838148904139694
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3546  WP_001219664.1  E8XD89  yhdG  321 aa tRNA dihydrouridine synthase DusB 0.035 ●○○○○ -0.84 -0.837298381977097
Escherichia coli M12  CO715_11815  ATI06331.1  130 aa TIGR00156 family protein 8.7e-11 ●○○○○ -0.84 -0.836997297937715
Escherichia coli M12  CO715_03040  ATI04804.1  72 aa hypothetical protein 7.4e-5 ●○○○○ -0.84 -0.836580005909217
Escherichia coli M12  CO715_01955  ATI04603.1  93 aa hypothetical protein 0.016 ●○○○○ -0.84 -0.836580005909217
Escherichia coli M12  CO715_01650  ATI04549.1  451 aa alpha-glucosidase/alpha-galactosidase 2.3e-6 ●○○○○ -0.84 -0.835954067866471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3929  AIK82477.1  296 aa 2-hydroxy-3-oxopropionate reductase <1e-323 ●○○○○ -0.84 -0.835873122857
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0568  WP_000708653.1  E8X922  fimH  335 aa type 1 fimbrin D-mannose specific adhesin FimH 0.00023 ●○○○○ -0.83 -0.834996376139136
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1460  NP_231103.1  P38443  427 aa hypothetical protein 1.1e-5 ●○○○○ -0.83 -0.834964982784374
Escherichia coli M12  CO715_07605  ATI05593.1  336 aa alcohol dehydrogenase AdhP 6.2e-60 ●○○○○ -0.83 -0.834702191780978
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1291  NP_230936.1  Q9KSG5  637 aa hypothetical protein 0.00013 ●○○○○ -0.83 -0.834664187678505
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3645  WP_014344416.1  E8XEI1  bigA  1964 aa autotransporter adhesin BigA 0.0068 ●○○○○ -0.83 -0.834475717430221
Acinetobacter baumannii ATCC 17978  A1S_1054  ABO11486.2  497 aa hypothetical protein 0.023 ●○○○○ -0.83 -0.834258420506885
Escherichia coli M12  CO715_08115  ATI05679.1  261 aa tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM 0.012 ●○○○○ -0.83 -0.833867607723982
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1484  WP_000412353.1  E8XI55  460 aa amino acid permease 9.7e-5 ●○○○○ -0.83 -0.83363145606107
Porphyromonas gingivalis ATCC 33277  PGN_1745  WP_010956414.1  B2RLL9  203 aa cytochrome c nitrite reductase small subunit <1e-323 ●○○○○ -0.83 -0.833426309349728
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3237  AIK81798.1  295 aa 5,10-methylenetetrahydrofolate reductase <1e-323 ●○○○○ -0.83 -0.833207001820077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3437  AIK81994.1  269 aa metQ 1.4e-11 ●○○○○ -0.83 -0.833172178957725
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2679  AIK81273.1  154 aa marR family protein 0.0095 ●○○○○ -0.83 -0.832806808025866
Escherichia coli CFT073  c1788  AAN80254.1  A0A0H2V8A1  ycjT  755 aa Hypothetical transport protein ycjT 0.033 ●○○○○ -0.83 -0.832567171437336
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1845  NP_231479.1  Q9KR02  ruvB  334 aa Holliday junction DNA helicase RuvB 9.2e-8 ●○○○○ -0.83 -0.83223531617806
Escherichia coli M12  CO715_06100  ATI05326.1  304 aa hypothetical protein 1.0e-27 ●○○○○ -0.83 -0.831989793595742
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0183  NP_232583.1  Q9KMY3  hmp  394 aa nitric oxide dioxygenase 3.6e-5 ●○○○○ -0.83 -0.831907168857476
Escherichia coli M12  CO715_16780  ATI07227.1  245 aa branched-chain amino acid ABC transporter permease 1.8e-44 ●○○○○ -0.83 -0.830737917510249
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1097  NP_230742.1  Q9KT08  pta  714 aa phosphate acetyltransferase 0.0012 ●○○○○ -0.83 -0.830586079735347
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0928  NP_233313.1  Q9KL21  169 aa hypothetical protein 0.00015 ●○○○○ -0.83 -0.830527985948892
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2643  NP_232271.1  Q9KNT7  argB  262 aa acetylglutamate kinase 2.4e-8 ●○○○○ -0.83 -0.830025662278978
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2201  WP_000136405.1  E8XCV4  wzc  719 aa tyrosine-protein kinase Wzc 0.0001 ●○○○○ -0.83 -0.829829080401885
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2232  AIK80837.1  227 aa extensin-like family protein 0.011 ●○○○○ -0.83 -0.829426480666695
Escherichia coli M12  CO715_04785  ATI05110.1  77 aa SirA-like protein 0.0043 ●○○○○ -0.83 -0.829277395410507
Escherichia coli M12  CO715_14440  ATI06801.1  144 aa universal stress protein A 3.2e-12 ●○○○○ -0.83 -0.828442811353512
Acinetobacter baumannii ATCC 17978  A1S_1176  ABO11606.2  A3M3W2  alaS  878 aa alanyl-tRNA synthetase 0.015 ●○○○○ -0.83 -0.828303455728115
Acinetobacter baumannii ATCC 17978  A1S_3010  ABO13411.2  601 aa hypothetical protein 0.00013 ●○○○○ -0.83 -0.828059193267129
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1227  WP_000456516.1  E8XFF7  ycfD  373 aa cupin domain-containing protein 0.00033 ●○○○○ -0.83 -0.82640780696763
Acinetobacter baumannii ATCC 17978  A1S_2437  ABO12855.2  162 aa putative Nudix hydrolase 0.0045 ●○○○○ -0.83 -0.826235839879306
Escherichia coli M12  CO715_09370  ATI05902.1  472 aa deoxyribodipyrimidine photo-lyase 2.8e-11 ●○○○○ -0.83 -0.825939059182525
Porphyromonas gingivalis ATCC 33277  PGN_1328  WP_012458188.1  B2RKF2  373 aa ABC transporter substrate-binding protein 1.9e-7 ●○○○○ -0.83 -0.825761461681078
Porphyromonas gingivalis ATCC 33277  PGN_1328  WP_051892388.1  B2RKF2  235 aa ATP-binding cassette domain-containing protein 1.9e-7 ●○○○○ -0.83 -0.825761461681078
Escherichia coli M12  CO715_09715  ATI05960.1  403 aa D-alanyl-D-alanine carboxypeptidase 4.4e-18 ●○○○○ -0.83 -0.825730413168277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2707  AIK81297.1  420 aa membrane fusion protein of the CusCFBA copper efflux system <1e-323 ●○○○○ -0.83 -0.825607372839241
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2305  WP_000169350.1  E8XDQ2  yeiR  328 aa GTP-binding protein 0.00012 ●○○○○ -0.83 -0.825419305415014
Escherichia coli M12  CO715_07125  ATI05508.1  79 aa DUF4222 domain-containing protein 7.1e-8 ●○○○○ -0.82 -0.824478537082783
Escherichia coli M12  CO715_00700  ATI04381.1  500 aa signal transduction histidine-protein kinase/phosphatase UhpB 1.3e-13 ●○○○○ -0.82 -0.824269891068534
Escherichia coli M12  CO715_12995  ATI06542.1  260 aa phospholipid ABC transporter permease 4.5e-15 ●○○○○ -0.82 -0.823852599040037
Escherichia coli M12  CO715_10385  ATI06069.1  121 aa multidrug transporter subunit MdtJ 1.0e-29 ●○○○○ -0.82 -0.823435307011539
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3001  AIK81586.1  293 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.82 -0.823289845989549
Escherichia coli M12  CO715_10945  ATI06169.1  792 aa phosphoenolpyruvate synthase 2.0e-26 ●○○○○ -0.82 -0.82322666099729
Escherichia coli M12  CO715_19025  ATI07623.1  403 aa BenE family transporter YdcO 6.3e-10 ●○○○○ -0.82 -0.822809368968792
Porphyromonas gingivalis ATCC 33277  PGN_1998  WP_004583707.1  B2RMC1  223 aa OmpA family protein 3.5e-6 ●○○○○ -0.82 -0.822756370105629
Retrieved entries 4,501–4,600 out of 36,363 total in 8.1 ms (Link to these results)