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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4057  AIK82604.1  40 aa hypothetical protein 4.4e-9 ●○○○○ -0.68 -0.67510321712607
Escherichia coli M12  CO715_03630  ATI04910.1  312 aa transcriptional regulator 5.4e-28 ●○○○○ -0.68 -0.675087990880599
Escherichia coli M12  CO715_01715  ATI08707.1  111 aa protein PhnA 1.0e-16 ●○○○○ -0.68 -0.675087990880599
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0421  NP_232815.1  Q9KME0  141 aa hypothetical protein 0.00021 ●○○○○ -0.67 -0.674928484931852
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1024  WP_010989008.1  E8XDI7  693 aa peptidase S14 0.0024 ●○○○○ -0.67 -0.674919652823455
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0626  WP_000002497.1  E8X977  ybdO  300 aa LysR family transcriptional regulator 0.024 ●○○○○ -0.67 -0.674595639385274
Escherichia coli M12  CO715_24670  ATI08621.1  120 aa hypothetical protein 0.0003 ●○○○○ -0.67 -0.673627468780857
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1507  NP_231148.2  Q9KRX6  353 aa 3-deoxy-7-phosphoheptulonate synthase 2.0e-6 ●○○○○ -0.67 -0.673557938390307
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1344  NP_230988.1  H9L4S8  369 aa 4-hydroxyphenylpyruvate dioxygenase 0.0014 ●○○○○ -0.67 -0.67318305453762
Porphyromonas gingivalis ATCC 33277  PGN_0922  WP_039417536.1  B2RJ96  397 aa virulence-associated protein E 9.0e-10 ●○○○○ -0.67 -0.67229358329273
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2173  AIK80778.1  392 aa oxidoreductase, Gfo/Idh/MocA family 7.6e-11 ●○○○○ -0.67 -0.67175861231512
Escherichia coli M12  CO715_16680  ATI07207.1  149 aa peptidoglycan-binding protein LysM 2.2e-6 ●○○○○ -0.67 -0.671541008638368
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2643  AIK81237.1  130 aa hypothetical protein 4.8e-13 ●○○○○ -0.67 -0.670461131413387
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3035  AIK81620.1  332 aa tRNA-dihydrouridine synthase A <1e-323 ●○○○○ -0.67 -0.67001010742712
Escherichia coli M12  CO715_21555  ATI08087.1  294 aa cytidine deaminase 1.3e-37 ●○○○○ -0.67 -0.669871840524377
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2269  AIK80874.1  308 aa phosphonate ABC transporter, periplasmic phosphonate binding protein 9.3e-5 ●○○○○ -0.67 -0.669536384796564
Escherichia coli M12  CO715_11180  ATI06215.1  344 aa arginine N-succinyltransferase 3.6e-16 ●○○○○ -0.67 -0.669454548495879
Escherichia coli M12  CO715_08760  ATI05796.1  248 aa amino acid ABC transporter substrate-binding protein 6.8e-23 ●○○○○ -0.67 -0.669245902481631
Acinetobacter baumannii ATCC 17978  A1S_2881  ABO13287.1  390 aa putative fatty acid desaturase 1.4e-5 ●○○○○ -0.67 -0.668932009029933
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1089  NP_230734.1  Q9KT16  270 aa periplasmic binding protein-like protein 3.3e-5 ●○○○○ -0.67 -0.668860276810153
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1985  NP_231619.1  Q9KQL3  566 aa long-chain-fatty-acid--CoA ligase 0.0012 ●○○○○ -0.67 -0.668219624792613
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3422  AIK81979.1  477 aa phosphotransferase system, EIIC family protein <1e-323 ●○○○○ -0.67 -0.668127852151044
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3410  AIK81967.1  440 aa PTS system, lactose/cellobiose IIC component family protein <1e-323 ●○○○○ -0.67 -0.668063771384784
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1352  AIK79975.1  1148 aa transcription-repair coupling factor <1e-323 ●○○○○ -0.67 -0.66787573121173
Escherichia coli M12  CO715_08085  ATI05674.1  215 aa MBL fold metallo-hydrolase 1.1e-12 ●○○○○ -0.67 -0.667159442339142
Porphyromonas gingivalis ATCC 33277  PGN_1534  WP_012458352.1  B2RL08  355 aa hypothetical protein 1.7e-5 ●○○○○ -0.67 -0.667016578159505
Escherichia coli M12  CO715_06080  ATI08745.1  315 aa GGDEF domain-containing protein 1.1e-20 ●○○○○ -0.67 -0.666950796324893
Escherichia coli M12  CO715_10105  ATI06026.1  70 aa cold-shock protein CspI 6.7e-8 ●○○○○ -0.67 -0.666950796324893
Acinetobacter baumannii ATCC 17978  A1S_0887  ABO11319.2  472 aa phosphomannomutase 0.00074 ●○○○○ -0.67 -0.666825132919095
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1468  WP_000361451.1  E8XI42  ydgT  51 aa division septum protein Blr 0.0053 ●○○○○ -0.67 -0.666301142561629
Escherichia coli M12  CO715_19815  ATI07766.1  54 aa DUF2496 domain-containing protein 2.8e-11 ●○○○○ -0.67 -0.665907566253649
Escherichia coli M12  CO715_08360  ATI05724.1  231 aa aquaporin 7.8e-9 ●○○○○ -0.67 -0.6656989202394
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3822  AIK82372.1  489 aa ribonuclease G <1e-323 ●○○○○ -0.67 -0.665058366456287
Acinetobacter baumannii ATCC 17978  A1S_2381  ABO12800.2  542 aa putative acinetobactin biosynthesis protein 0.00084 ●○○○○ -0.66 -0.664809724704468
Escherichia coli CFT073  c1251  AAN79708.1  A0A0H2V871  iroE  318 aa IroE protein 9.9e-8 ●○○○○ -0.66 -0.664731817296556
Escherichia coli M12  CO715_18130  ATI07466.1  347 aa ABC transporter substrate-binding protein 5.3e-10 ●○○○○ -0.66 -0.664238398139658
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3158  WP_000201030.1  E8X9I3  galR  342 aa HTH-type transcriptional regulator GalR 0.0068 ●○○○○ -0.66 -0.664226234609724
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0591  NP_232981.1  Q9KLZ8  611 aa peptide ABC transporter substrate-binding protein 6.5e-6 ●○○○○ -0.66 -0.663846222131599
Porphyromonas gingivalis ATCC 33277  PGN_0316  WP_012457420.1  B2RHJ0  614 aa precorrin-4 C(11)-methyltransferase 1.8e-9 ●○○○○ -0.66 -0.662894808797887
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0540  NP_232930.1  Q9KM49  483 aa formate transporter 1 0.0014 ●○○○○ -0.66 -0.662009971288838
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1867  AIK80473.1  382 aa rare lipoA family protein 0.007 ●○○○○ -0.66 -0.659338195391209
Porphyromonas gingivalis ATCC 33277  PGN_1121  WP_004585529.1  B2RJU5  104 aa NAD(P) transhydrogenase subunit alpha <1e-323 ●○○○○ -0.66 -0.658691943788804
Acinetobacter baumannii ATCC 17978  A1S_0414  ABO10869.2  A3M1S5  rppH  161 aa (di)nucleoside polyphosphate hydrolase (Ap5A pyrophosphatase) 0.0051 ●○○○○ -0.66 -0.658593111501567
Acinetobacter baumannii ATCC 17978  A1S_3029  ABO13426.1  246 aa putative tRNA-i(6)A37 modification enzyme 2.7e-5 ●○○○○ -0.66 -0.657834264758274
Escherichia coli M12  CO715_19385  ATI07690.1  421 aa 4-aminobutyrate transaminase 1.0e-8 ●○○○○ -0.66 -0.657353079669445
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1617  NP_231257.1  Q9KRL9  296 aa LysR family transcriptional regulator 1.4e-8 ●○○○○ -0.66 -0.656759252170431
Escherichia coli M12  CO715_02240  ATI04656.1  533 aa malate synthase A 5.7e-32 ●○○○○ -0.66 -0.656727141626699
Escherichia coli M12  CO715_21505  ATI08077.1  385 aa DUF418 family protein 0.00048 ●○○○○ -0.66 -0.656309849598201
Porphyromonas gingivalis ATCC 33277  PGN_0003  WP_012457160.1  B2RGM7  339 aa acyltransferase <1e-323 ●○○○○ -0.66 -0.656022586664728
Escherichia coli M12  CO715_04080  ATI04992.1  393 aa MFS transporter 2.4e-6 ●○○○○ -0.66 -0.655266619526957
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2028  AIK80634.1  265 aa ABC transporter family protein 1.3e-15 ●○○○○ -0.66 -0.655138322934473
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0688  NP_230337.1  Q9KU41  113 aa hypothetical protein 8.9e-6 ●○○○○ -0.65 -0.65488945288475
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2104  WP_000189662.1  E8XB85  cobQ  506 aa cobyric acid synthase 0.013 ●○○○○ -0.65 -0.654869845638262
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1233  NP_230878.1  Q9KSM3  129 aa hypothetical protein 0.00038 ●○○○○ -0.65 -0.654773203235161
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3074  WP_001092263.1  E8X8L3  cysN  479 aa sulfate adenylyltransferase subunit CysN 0.0044 ●○○○○ -0.65 -0.654260455257932
Escherichia coli M12  CO715_14695  ATI06850.1  119 aa hypothetical protein 0.024 ●○○○○ -0.65 -0.653388805398717
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4889  AIK83416.1  547 aa yojI 0.049 ●○○○○ -0.65 -0.653338081241664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1625  AIK80245.1  113 aa D-alanyl-D-alanine carboxypeptidase family protein <1e-323 ●○○○○ -0.65 -0.653327112740286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4046  AIK82593.1  395 aa cystathionine beta-lyase <1e-323 ●○○○○ -0.65 -0.653121131912408
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4717  WP_000233260.1  E8XCF9  yjiJ  394 aa MFS transporter 0.0022 ●○○○○ -0.65 -0.652733534432894
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0432  WP_000752021.1  E8XKJ9  tsx  287 aa nucleoside-specific channel-forming protein Tsx 0.0025 ●○○○○ -0.65 -0.65215150155214
Escherichia coli M12  CO715_21625  ATI08097.1  305 aa ABC transporter substrate-binding protein 2.6e-5 ●○○○○ -0.65 -0.650885053227731
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1059  NP_233441.1  Q9KKP3  205 aa hypothetical protein 1.7e-5 ●○○○○ -0.65 -0.650845469017576
Escherichia coli M12  CO715_09510  ATI05928.1  250 aa ribonucleotide monophosphatase NagD 2.1e-5 ●○○○○ -0.65 -0.650676407213482
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2939  AIK81525.1  196 aa regulator 3.4e-8 ●○○○○ -0.65 -0.650029246384033
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1676  AIK80296.1  522 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ●○○○○ -0.65 -0.649849299454252
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3482  AIK82038.1  295 aa hlyD secretion family protein 1.4e-10 ●○○○○ -0.65 -0.64944347158008
Porphyromonas gingivalis ATCC 33277  PGN_0556  WP_012457595.1  B2RI80  1469 aa cobaltochelatase subunit CobN <1e-323 ●○○○○ -0.65 -0.64942749254021
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3477  AIK82033.1  248 aa phosphoenolpyruvate phosphomutase family protein <1e-323 ●○○○○ -0.65 -0.648743520620313
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3898  AIK82447.1  447 aa argininosuccinate synthase <1e-323 ●○○○○ -0.65 -0.648672120080557
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4755  WP_000211207.1  E8XCJ7  354 aa GGDEF domain-containing protein 0.028 ●○○○○ -0.65 -0.648574329838217
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0011  WP_001258094.1  E8XG31  yaai  134 aa DUF2541 family protein 0.0026 ●○○○○ -0.65 -0.648453960475283
Escherichia coli M12  CO715_16965  ATI07257.1  255 aa formate hydrogenlyase 4.1e-10 ●○○○○ -0.65 -0.648381301056744
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3895  AIK82444.1  115 aa yfaZ family protein <1e-323 ●○○○○ -0.65 -0.647438689120258
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2368  NP_231998.1  Q9KPJ9  238 aa two-component response regulator 0.00019 ●○○○○ -0.65 -0.64626054237983
Acinetobacter baumannii ATCC 17978  A1S_3173  ABO13570.1  127 aa hypothetical protein 0.00017 ●○○○○ -0.65 -0.646061447851377
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4698  AIK83232.1  188 aa gcvR GcvR predicted transcriptional regulator 0.00018 ●○○○○ -0.65 -0.645863526758189
Escherichia coli M12  CO715_20720  ATI07932.1  385 aa glucan biosynthesis protein C 4.0e-83 ●○○○○ -0.65 -0.645668902871509
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3737  AIK82292.1  187 aa flavodoxin-like fold family protein <1e-323 ●○○○○ -0.65 -0.645321131103703
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0406  NP_232800.1  Q9KMF4  171 aa lipoprotein Blc 0.0023 ●○○○○ -0.65 -0.64524995837154
Escherichia coli M12  CO715_12175  ATI06399.1  178 aa general secretion pathway protein 1.4e-11 ●○○○○ -0.64 -0.644625672800265
Escherichia coli M12  CO715_17415  ATI07341.1  366 aa 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM 1.4e-25 ●○○○○ -0.64 -0.643999734757518
Porphyromonas gingivalis ATCC 33277  PGN_0004  WP_012457161.1  B2RGM8  cobB  234 aa NAD-dependent deacylase <1e-323 ●○○○○ -0.64 -0.643824780148059
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2099  AIK80704.1  125 aa hypothetical protein 0.022 ●○○○○ -0.64 -0.643805590434011
Escherichia coli M12  CO715_21000  ATI07987.1  265 aa metal-dependent hydrolase 0.00077 ●○○○○ -0.64 -0.643373796714772
Escherichia coli M12  CO715_00115  ATI04278.1  337 aa cytoskeleton protein RodZ 0.023 ●○○○○ -0.64 -0.642121920629279
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3708  AIK82263.1  414 aa protein involved in utilization of DNA as a carbon source 3.4e-13 ●○○○○ -0.64 -0.641702131495385
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4063  WP_001056260.1  E8XIK4  rbsB  296 aa ribose ABC transporter substrate-binding protein RbsB 0.034 ●○○○○ -0.64 -0.641075491718853
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4115  AIK82661.1  398 aa pyridine nucleotide-disulfide oxidoreductase family protein 2.1e-5 ●○○○○ -0.64 -0.640068723623129
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3214  WP_000389833.1  E8X9N8  yggB  286 aa small-conductance mechanosensitive channel MscS 0.0058 ●○○○○ -0.64 -0.638859256939076
Escherichia coli M12  CO715_16310  ATI07139.1  152 aa division/cell wall cluster transcriptional repressor MraZ 1.1e-22 ●○○○○ -0.64 -0.63815764635855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4253  AIK82798.1  289 aa bacterial regulatory helix-turn-helix, lysR family protein 3.2e-7 ●○○○○ -0.64 -0.638128663563996
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5162  AIK83683.1  192 aa phage antitermination Q family protein 0.00022 ●○○○○ -0.64 -0.638074286603839
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1000  NP_233384.1  Q9KKV0  209 aa hypothetical protein 0.00045 ●○○○○ -0.64 -0.637961897308028
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2343  NP_231973.1  Q9KPM4  radA  459 aa DNA repair protein RadA 0.0014 ●○○○○ -0.64 -0.636796496402547
Escherichia coli M12  CO715_06040  ATI05316.1  221 aa stress protection protein MarC 0.002 ●○○○○ -0.64 -0.636697124258808
Porphyromonas gingivalis ATCC 33277  PGN_1965  WP_012458648.1  B2RM88  195 aa hypothetical protein 2.6e-12 ●○○○○ -0.64 -0.636573302994387
Escherichia coli M12  CO715_01180  ATI04465.1  475 aa MFS transporter 1.6e-7 ●○○○○ -0.64 -0.635653894187564
Acinetobacter baumannii ATCC 17978  A1S_0431  ABO10886.2  311 aa lipid A biosynthesis lauroyl acyltransferase 3.9e-5 ●○○○○ -0.64 -0.635540896481904
Escherichia coli M12  CO715_04845  ATI05118.1  461 aa two-component system response regulator 2.6e-7 ●○○○○ -0.64 -0.635236602159066
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