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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_18230  ATI07484.1  663 aa transketolase 2.4e-10 ●○○○○ -0.48 -0.477500215386927
Acinetobacter baumannii ATCC 17978  A1S_1957  ABO12384.2  416 aa putative L-kynurenine hydrolase 0.0039 ●○○○○ -0.48 -0.477152217169536
Escherichia coli M12  CO715_22190  ATI08202.1  367 aa UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase 0.0001 ●○○○○ -0.48 -0.476456985315683
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1030  WP_000478859.1  E8XDJ3  132 aa phage minor tail protein G 0.015 ●○○○○ -0.48 -0.476406033127134
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1967  WP_000920611.1  E8XA81  ftn  165 aa non-heme ferritin 0.022 ●○○○○ -0.48 -0.475731914840487
Escherichia coli M12  CO715_09755  ATI05968.1  262 aa hydrolase 2.9e-9 ●○○○○ -0.48 -0.475205109230189
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0795  NP_230444.1  Q9KTU3  448 aa citrate/sodium symporter 3.3e-5 ●○○○○ -0.48 -0.47517329105025
Escherichia coli M12  CO715_13290  ATI06596.1  646 aa RNase E specificity factor CsrD 2.2e-18 ●○○○○ -0.47 -0.474579171187443
Acinetobacter baumannii ATCC 17978  A1S_1481  ABO11909.2  363 aa putative GTP-binding protein 0.0011 ●○○○○ -0.47 -0.474565560374997
Porphyromonas gingivalis ATCC 33277  PGN_1362  WP_012458218.1  B2RKI6  521 aa lytic transglycosylase F 6.7e-16 ●○○○○ -0.47 -0.474564086866825
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1735  NP_231371.1  Q9KRA7  aat  243 aa leucyl/phenylalanyl-tRNA--protein transferase 0.0064 ●○○○○ -0.47 -0.474304066496252
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4204  AIK82749.1  137 aa crcB-like family protein 8.4e-8 ●○○○○ -0.47 -0.473740798391913
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3725  AIK82280.1  189 aa cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD family protein 2.3e-8 ●○○○○ -0.47 -0.472919359349462
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1931  AIK80537.1  1293 aa amino acid adenylation domain protein 0.00016 ●○○○○ -0.47 -0.472665772170851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3815  AIK82365.1  333 aa sulfoxide reductase catalytic subunit yedY 0.016 ●○○○○ -0.47 -0.472358346823231
Escherichia coli M12  CO715_07280  ATI05535.1  357 aa electron transporter YccM 1.6e-8 ●○○○○ -0.47 -0.471866773002208
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3572  AIK82127.1  337 aa dppF 1.1e-16 ●○○○○ -0.47 -0.471634174907357
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4857  AIK83384.1  458 aa O-succinylbenzoate-CoA ligase 0.0022 ●○○○○ -0.47 -0.470925063634301
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3698  AIK82253.1  540 aa phosphoenolpyruvate carboxykinase <1e-323 ●○○○○ -0.47 -0.470335923290608
Porphyromonas gingivalis ATCC 33277  PGN_0223  WP_012457342.1  B2RH97  wecA  368 aa undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase <1e-323 ●○○○○ -0.47 -0.47025546365703
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4753  WP_000058276.1  E8XCJ5  152 aa YbaK/EbsC family protein 0.039 ●○○○○ -0.47 -0.470010463556095
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1043  NP_230688.1  Q9KT62  428 aa long-chain fatty acid transport protein 0.00014 ●○○○○ -0.47 -0.46921469575271
Escherichia coli M12  CO715_19920  ATI07785.1  272 aa HMP-PP phosphatase 0.036 ●○○○○ -0.47 -0.468945728802724
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1193  NP_230838.1  Q9KSR3  65 aa hypothetical protein 0.00033 ●○○○○ -0.47 -0.468639219707682
Escherichia coli M12  CO715_03140  ATI04818.1  415 aa PTS fructose transporter subunit IIC 0.0022 ●○○○○ -0.47 -0.467067914674484
Escherichia coli M12  CO715_18575  ATI07544.1  559 aa peptide ABC transporter substrate-binding protein 8.4e-5 ●○○○○ -0.47 -0.466441976631737
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2205  WP_001252270.1  E8XCV8  asmA  618 aa outer membrane assembly protein AsmA 0.0027 ●○○○○ -0.47 -0.466304511657994
Escherichia coli M12  CO715_23755  ATI08457.1  482 aa two-component sensor histidine kinase 0.00016 ●○○○○ -0.47 -0.466233330617489
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0420  NP_230074.1  Q9KUU5  1291 aa hypothetical protein 1.6e-6 ●○○○○ -0.47 -0.46581898347531
Escherichia coli M12  CO715_21425  ATI08061.1  416 aa NupC/NupG family nucleoside CNT transporter 2.4e-18 ●○○○○ -0.47 -0.465190100546244
Escherichia coli M12  CO715_04270  ATI05029.1  179 aa stationary phase growth adaptation protein 5.4e-6 ●○○○○ -0.47 -0.465190100546244
Escherichia coli M12  CO715_22695  ATI08286.1  214 aa hypothetical protein 2.8e-21 ●○○○○ -0.46 -0.464355516489249
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0593  NP_232983.1  Q9KLZ6  310 aa hypothetical protein 0.0096 ●○○○○ -0.46 -0.463734616329696
Escherichia coli M12  CO715_22955  ATI08333.1  85 aa DUF3343 domain-containing protein 2.1e-117 ●○○○○ -0.46 -0.462894994389507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3953  AIK82501.1  329 aa oxidoreductase, NAD-binding Rossmann fold family protein <1e-323 ●○○○○ -0.46 -0.462649045825629
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1348  NP_230992.2  Q9KSB1  379 aa response regulator 7.6e-6 ●○○○○ -0.46 -0.462409611840233
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3615  AIK82170.1  132 aa nickel-responsive transcriptional regulator NikR <1e-323 ●○○○○ -0.46 -0.462346607518332
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0800  NP_233186.1  Q9KLE6  160 aa creA protein 0.044 ●○○○○ -0.46 -0.462113172336819
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0987  NP_233371.1  Q9KKW3  803 aa phosphoenolpyruvate synthase 0.0028 ●○○○○ -0.46 -0.462056894651174
Acinetobacter baumannii ATCC 17978  A1S_0567  ABO11020.2  104 aa pyridine nucleotide transhydrogenase (proton pump) alpha subunit (part2) 0.01 ●○○○○ -0.46 -0.462030961263409
Escherichia coli M12  CO715_11470  ATI06269.1  536 aa BCCT family transporter 7.4e-17 ●○○○○ -0.46 -0.461851764318263
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2798  AIK81387.1  254 aa tRNA- family protein 0.00045 ●○○○○ -0.46 -0.461694972158763
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0037  NP_232438.1  Q9KNC8  150 aa hypothetical protein 0.0043 ●○○○○ -0.46 -0.461682016051674
Escherichia coli M12  CO715_10975  ATI06175.1  237 aa EAL domain-containing protein 2.8e-29 ●○○○○ -0.46 -0.461434472289765
Escherichia coli M12  CO715_23875  ATI08480.1  477 aa glycogen synthase 1.1e-25 ●○○○○ -0.46 -0.461225826275516
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0155  NP_232555.1  Q9KN11  498 aa NADH dehydrogenase 2.1e-5 ●○○○○ -0.46 -0.460979784223204
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1619  AIK80239.1  394 aa baseplate J-like family protein <1e-323 ●○○○○ -0.46 -0.460189104149127
Escherichia coli M12  CO715_07870  ATI05635.1  358 aa hypothetical protein 1.2e-59 ●○○○○ -0.46 -0.459973950190023
Escherichia coli M12  CO715_22740  ATI08295.1  260 aa metal-dependent hydrolase 2.0e-11 ●○○○○ -0.46 -0.459973950190023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3094  AIK81675.1  223 aa endonuclease V 7.0e-10 ●○○○○ -0.46 -0.459953888346532
Escherichia coli M12  CO715_12080  ATI06381.1  407 aa glycolate oxidase iron-sulfur subunit 0.0016 ●○○○○ -0.46 -0.459765304175774
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4034  AIK82581.1  219 aa qseB transcriptional activator 2.2e-12 ●○○○○ -0.46 -0.45965435921475
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4914  AIK83440.1  234 aa protein with low undecaprenyl pyrophosphate phosphatase activity 0.015 ●○○○○ -0.46 -0.459460735208506
Escherichia coli M12  CO715_05690  ATI05263.1  605 aa DNA primase 6.2e-19 ●○○○○ -0.46 -0.459348012147276
Escherichia coli M12  CO715_07145  ATI05512.1  217 aa 23S rRNA pseudouridine(2457) synthase RluE 7.7e-6 ●○○○○ -0.46 -0.459348012147276
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1753  NP_231389.1  Q9KR89  434 aa paraquat-inducible protein A 0.0022 ●○○○○ -0.46 -0.459107243539881
Porphyromonas gingivalis ATCC 33277  PGN_1524  WP_012458343.1  B2RKZ8  821 aa polysaccharide biosynthesis tyrosine autokinase <1e-323 ●○○○○ -0.46 -0.458420428141337
Porphyromonas gingivalis ATCC 33277  PGN_0291  WP_012457399.1  B2RHG5  1228 aa VWA domain-containing protein <1e-323 ●○○○○ -0.46 -0.458356558778859
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1611  NP_231251.1  Q9KRM5  metAS  319 aa homoserine O-succinyltransferase 4.7e-8 ●○○○○ -0.46 -0.457957233959302
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3134  WP_000678626.1  E8X8S3  mltA  365 aa murein transglycosylase A 0.024 ●○○○○ -0.46 -0.457241980038098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4602  AIK83135.1  245 aa putative S-adenosyl-L-methionine-dependent methyltransferase 1.7e-5 ●○○○○ -0.46 -0.45721137507179
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0031  NP_232432.1  Q9KND4  521 aa methyl-accepting chemotaxis protein 0.013 ●○○○○ -0.46 -0.457056059731913
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4276  AIK82821.1  257 aa uxuR transcriptional repressor 0.0007 ●○○○○ -0.46 -0.45670843275178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3667  AIK82222.1  231 aa pirin-like protein <1e-323 ●○○○○ -0.46 -0.456598062404465
Porphyromonas gingivalis ATCC 33277  PGN_0270  WP_012457382.1  B2RHE4  246 aa ComF family protein <1e-323 ●○○○○ -0.46 -0.456431404369799
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4448  AIK82991.1  373 aa hydrogenase expression/formation protein HypD <1e-323 ●○○○○ -0.46 -0.455262027819293
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3701  AIK82256.1  227 aa HAD hydrolase, IA, variant 3 family protein 6.5e-10 ●○○○○ -0.45 -0.454803535329265
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3661  WP_001519362.1  E8XEJ7  nudE  198 aa ADP compounds hydrolase NudE 0.039 ●○○○○ -0.45 -0.454800875751739
Escherichia coli M12  CO715_22650  ATI08280.1  215 aa phosphoglycerate mutase GpmB 0.026 ●○○○○ -0.45 -0.454340507805303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3540  AIK82096.1  440 aa xylose isomerase <1e-323 ●○○○○ -0.45 -0.453038147248505
Escherichia coli M12  CO715_18830  ATI07590.1  243 aa laccase domain-containing protein 0.0036 ●○○○○ -0.45 -0.452671339691313
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0109  NP_232510.1  Q9KN56  145 aa hypothetical protein 0.0062 ●○○○○ -0.45 -0.452626244538964
Escherichia coli M12  CO715_20700  ATI07929.1  110 aa curli assembly protein CsgC 3.5e-20 ●○○○○ -0.45 -0.452462693677064
Escherichia coli M12  CO715_00425  ATI04332.1  271 aa AraC family transcriptional regulator 0.00011 ●○○○○ -0.45 -0.452254047662815
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2124  WP_000097497.1  E8XBZ3  pduB  270 aa propanediol utilization microcompartment protein PduB 0.043 ●○○○○ -0.45 -0.452224405331892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3960  AIK82508.1  323 aa lsrR transcriptional repressor <1e-323 ●○○○○ -0.45 -0.451848465229741
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0925  WP_000491118.1  E8XCP6  ybjE  299 aa lysine exporter LysO family protein 0.024 ●○○○○ -0.45 -0.451008063273167
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1300  NP_230945.1  Q9KSF6  453 aa L-serine dehydratase 1 1.9e-6 ●○○○○ -0.45 -0.450175500753579
Escherichia coli M12  CO715_12300  ATI06418.1  487 aa anion permease 6.8e-14 ●○○○○ -0.45 -0.450167587520326
Escherichia coli M12  CO715_19165  ATI07649.1  286 aa oxidoreductase 8.4e-15 ●○○○○ -0.45 -0.449750295491828
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0121  NP_229780.1  Q9KVM0  48 aa hypothetical protein 0.001 ●○○○○ -0.45 -0.44906846419736
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0006  NP_232407.1  Q9KNF8  239 aa hypothetical protein 1.8e-5 ●○○○○ -0.45 -0.448746264094931
Escherichia coli M12  CO715_10970  ATI06174.1  478 aa SELO family protein 1.2e-41 ●○○○○ -0.45 -0.448707065420584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3674  AIK82229.1  658 aa glycogen debranching enzyme GlgX <1e-323 ●○○○○ -0.45 -0.448297795276435
Escherichia coli M12  CO715_01225  ATI04473.1  91 aa DUF1471 domain-containing protein 3.1e-5 ●○○○○ -0.45 -0.448081127377838
Acinetobacter baumannii ATCC 17978  A1S_0842  ABO11276.1  245 aa hypothetical protein 0.0029 ●○○○○ -0.45 -0.447849319833781
Acinetobacter baumannii ATCC 17978  A1S_0649  ABO11098.2  616 aa putative phage primase 0.0024 ●○○○○ -0.45 -0.446782734980215
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3257  AIK81818.1  232 aa response regulator 0.0011 ●○○○○ -0.45 -0.446604015910168
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0029  NP_232430.1  Q9KND6  244 aa transcriptional regulator 0.004 ●○○○○ -0.45 -0.445348746777388
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0194  NP_229851.1  Q9KVF2  588 aa gamma-glutamyltranspeptidase 5.4e-5 ●○○○○ -0.45 -0.445043436857798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4227  AIK82772.1  301 aa minor fimbrial subunit, D-mannose specific adhesin 9.3e-12 ●○○○○ -0.44 -0.444841259974266
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3665  AIK82220.1  217 aa polymer-forming cytoskeletal family protein <1e-323 ●○○○○ -0.44 -0.44422823649631
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4337  AIK82882.1  236 aa precorrin-2 C20-methyltransferase <1e-323 ●○○○○ -0.44 -0.444048352762831
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2382  WP_001285726.1  E8XEC8  glpC  396 aa anaerobic glycerol-3-phosphate dehydrogenase subunit C 0.028 ●○○○○ -0.44 -0.443981230824319
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4173  AIK82718.1  309 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.44 -0.443811802616754
Escherichia coli M12  CO715_11430  ATI06263.1  32 aa hypothetical protein 0.00099 ●○○○○ -0.44 -0.443699561078612
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4418  AIK82961.1  197 aa phenolic acid decarboxylase subunit B 0.0025 ●○○○○ -0.44 -0.443594197693314
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2278  NP_231909.1  Q9KPT4  430 aa hypothetical protein 2.3e-5 ●○○○○ -0.44 -0.442603698490788
Escherichia coli M12  CO715_09315  ATI05892.1  188 aa type 1 fimbrial protein 6.5e-27 ●○○○○ -0.44 -0.442447684993118
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3229  WP_000853913.1  E8X9Q3  338 aa zinc-binding alcohol dehydrogenase family protein 0.024 ●○○○○ -0.44 -0.442303537355923
Retrieved entries 5,601–5,700 out of 36,363 total in 8.3 ms (Link to these results)