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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_20195  ATI07838.1  302 aa fructokinase 0.022 ●○○○○ -0.38 -0.379436588689962
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3621  AIK82176.1  286 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.38 -0.379395812484161
Acinetobacter baumannii ATCC 17978  A1S_0492  ABO10945.2  339 aa beta-N-acetyl-D-glucosaminidase 0.0097 ●○○○○ -0.38 -0.379262259740235
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2298  NP_231929.1  Q9KPR8  206 aa lipoprotein 8.9e-6 ●○○○○ -0.38 -0.378893015999154
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0073  NP_232474.1  Q9KN92  pstB2  251 aa phosphate ABC transporter ATP-binding protein 0.037 ●○○○○ -0.38 -0.378657034307202
Acinetobacter baumannii ATCC 17978  A1S_3199  ABO13592.2  110 aa hypothetical protein 0.043 ●○○○○ -0.38 -0.377438642362752
Escherichia coli M12  CO715_06555  ATI05406.1  92 aa hypothetical protein 7.1e-13 ●○○○○ -0.38 -0.376932836518976
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1673  NP_231309.1  Q9KRG9  1037 aa AcrB/AcrD/AcrF family transporter 3.2e-6 ●○○○○ -0.38 -0.376912628059942
Escherichia coli M12  CO715_10125  ATI06030.1  71 aa lysis protein S 1.1e-16 ●○○○○ -0.38 -0.376306898476229
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3589  AIK82144.1  1159 aa tetratricopeptide repeat family protein <1e-323 ●○○○○ -0.38 -0.37600074266004
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2248  AIK80853.1  459 aa ethanolamine permease <1e-323 ●○○○○ -0.37 -0.374784953754055
Escherichia coli M12  CO715_11045  ATI06189.1  252 aa DUF481 domain-containing protein 2.5e-7 ●○○○○ -0.37 -0.374637730362239
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4512  AIK83050.1  136 aa nrdI protein 0.0021 ●○○○○ -0.37 -0.374342702614466
Porphyromonas gingivalis ATCC 33277  PGN_1538  WP_051892399.1  B2RL12  1010 aa efflux RND transporter permease subunit 4.7e-14 ●○○○○ -0.37 -0.373939698381232
Escherichia coli M12  CO715_25145  ATI08677.1  115 aa antirestriction protein 5.4e-12 ●○○○○ -0.37 -0.373385854276745
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4161  AIK82707.1  237 aa dsbCreduced <1e-323 ●○○○○ -0.37 -0.373120073772585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2531  AIK81128.1  177 aa general stress protein 14 0.0019 ●○○○○ -0.37 -0.372881449722388
Escherichia coli M12  CO715_13060  ATI06555.1  210 aa hypothetical protein 2.7e-19 ●○○○○ -0.37 -0.372342624205501
Escherichia coli M12  CO715_16655  ATI07204.1  388 aa Na+/H+ antiporter NhaA 0.00045 ●○○○○ -0.37 -0.372342624205501
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1817  NP_231451.1  Q9KR30  587 aa Fis family transcriptional regulator 0.0013 ●○○○○ -0.37 -0.372275713481355
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1042  NP_230687.1  Q9KT63  432 aa long-chain fatty acid transport protein 8.9e-5 ●○○○○ -0.37 -0.372134339112649
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3267  AIK81828.1  322 aa rhamnose ABC transporter, rhamnose-binding protein <1e-323 ●○○○○ -0.37 -0.371926520428519
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4428  AIK82971.1  97 aa hypothetical protein 3.0e-10 ●○○○○ -0.37 -0.370895097905068
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1044  NP_230689.1  Q9KT61  253 aa hypothetical protein 0.00029 ●○○○○ -0.37 -0.370856062761915
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3062  AIK81647.1  449 aa aspartate kinase, monofunctional class 6.7e-11 ●○○○○ -0.37 -0.370611374967028
Escherichia coli M12  CO715_04685  ATI05093.1  207 aa helix-turn-helix transcriptional regulator 6.6e-39 ●○○○○ -0.37 -0.370464810077261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3399  WP_022562449.1  E8XC62  tdcA  76 aa hypothetical protein 0.049 ●○○○○ -0.37 -0.370189393854241
Escherichia coli M12  CO715_04335  ATI08722.1  231 aa DUF1481 domain-containing protein 3.1e-77 ●○○○○ -0.37 -0.370047518048764
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1171  NP_230816.1  Q9KST5  trpCF  469 aa bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.0011 ●○○○○ -0.37 -0.369041161107961
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2456  AIK81053.1  468 aa sugar (Glycoside-Pentoside-Hexuronide) transporter domain protein <1e-323 ●○○○○ -0.37 -0.368435137122301
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3268  AIK81829.1  503 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ●○○○○ -0.37 -0.36785323084818
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4262  AIK82807.1  413 aa lacY lactose MFS transporter <1e-323 ●○○○○ -0.37 -0.367489094983664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3697  AIK82252.1  451 aa envZ <1e-323 ●○○○○ -0.37 -0.366922745312122
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1571  NP_231211.1  Q9KRR5  445 aa quinol oxidase subunit I 1.8e-10 ●○○○○ -0.37 -0.366617650433934
Escherichia coli M12  CO715_16710  ATI07213.1  114 aa hypothetical protein 7.6e-15 ●○○○○ -0.37 -0.366500535806533
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1879  NP_231513.1  Q9KQW8  752 aa Rec2-like protein 4.1e-5 ●○○○○ -0.37 -0.366423283122741
Porphyromonas gingivalis ATCC 33277  PGN_0086  WP_012457230.1  B2RGW0  1828 aa DNA methylase 2.5e-10 ●○○○○ -0.37 -0.366297599305696
Escherichia coli M12  CO715_11925  ATI06353.1  47 aa carboxymethylenebutenolidase 1.0e-6 ●○○○○ -0.37 -0.366291889792284
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0098  NP_229757.1  Q9KVP3  659 aa methyl-accepting chemotaxis protein 0.00015 ●○○○○ -0.37 -0.366014474080958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3076  AIK81661.1  276 aa iclR transcriptional repressor 3.7e-10 ●○○○○ -0.37 -0.365702998304382
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1203  NP_230848.1  Q9KSQ3  hutU  565 aa urocanate hydratase 0.00025 ●○○○○ -0.36 -0.364991232763183
Acinetobacter baumannii ATCC 17978  A1S_2995  ABO13396.2  224 aa putative membrane protein 0.013 ●○○○○ -0.36 -0.364781749540799
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0725  NP_230374.1  Q9KU05  548 aa phosphate ABC transporter permease 8.8e-7 ●○○○○ -0.36 -0.364767667764604
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1023  NP_233407.1  Q9KKS7  619 aa hypothetical protein 0.006 ●○○○○ -0.36 -0.364498204156227
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1723  AIK80343.1  546 aa sulfatase family protein <1e-323 ●○○○○ -0.36 -0.364222350090084
Escherichia coli M12  CO715_22960  ATI08334.1  286 aa hypothetical protein 2.7e-12 ●○○○○ -0.36 -0.363996783635547
Porphyromonas gingivalis ATCC 33277  PGN_0450  WP_012457515.1  B2RHX4  174 aa RNA polymerase sigma factor <1e-323 ●○○○○ -0.36 -0.363796759332169
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2682  NP_232310.1  Q9KNP9  metJ  105 aa transcriptional repressor protein MetJ 0.001 ●○○○○ -0.36 -0.363791714761253
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0197  NP_232597.1  Q9KMW9  guaC  347 aa guanosine 5'-monophosphate oxidoreductase 6.8e-6 ●○○○○ -0.36 -0.363679494132252
Escherichia coli M12  CO715_00305  ATI04313.1  475 aa two-component sensor histidine kinase 5.6e-5 ●○○○○ -0.36 -0.363579491607049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2985  AIK81570.1  139 aa molybdopterin oxidoreductase family protein 3.0e-6 ●○○○○ -0.36 -0.363095202422132
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2979  AIK81564.1  332 aa branched-chain amino acid transport system / permease component family protein 0.028 ●○○○○ -0.36 -0.363035258708979
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0516  NP_232907.1  Q9KM72  580 aa PTS system fructose-specific transporter subunit IIBC 0.00014 ●○○○○ -0.36 -0.362964113606971
Escherichia coli M12  CO715_05605  ATI08736.1  479 aa 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF 0.00098 ●○○○○ -0.36 -0.362953553564302
Acinetobacter baumannii ATCC 17978  A1S_0264  ABO10739.1  169 aa hypothetical protein 0.019 ●○○○○ -0.36 -0.36262402567939
Escherichia coli M12  CO715_16920  ATI07250.1  479 aa anaerobic nitric oxide reductase flavorubredoxin 5.0e-18 ●○○○○ -0.36 -0.362536261535805
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2634  AIK81228.1  340 aa putative L-galactonate oxidoreductase 3.9e-15 ●○○○○ -0.36 -0.361590847282446
Escherichia coli M12  CO715_23430  ATI08404.1  94 aa malate transporter 3.2e-9 ●○○○○ -0.36 -0.361284385450311
Escherichia coli M12  CO715_20475  ATI07890.1  427 aa cytosine deaminase 0.0046 ●○○○○ -0.36 -0.361075739436062
Porphyromonas gingivalis ATCC 33277  PGN_0756  WP_012457755.1  B2RIT0  dpp5  684 aa S9 family peptidase 0.013 ●○○○○ -0.36 -0.360575233684083
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0723  NP_233110.1  Q9KLM0  436 aa 3-hydroxy-3-methylglutaryl-CoA reductase 0.0016 ●○○○○ -0.36 -0.360341049505648
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1591  AIK80211.1  242 aa ABC transporter family protein 6.8e-5 ●○○○○ -0.36 -0.359989325818215
Escherichia coli M12  CO715_04470  ATI05057.1  484 aa AMP nucleosidase 3.6e-5 ●○○○○ -0.36 -0.359823863350569
Escherichia coli M12  CO715_02285  ATI04662.1  143 aa rhodanese-like domain-containing protein 8.3e-7 ●○○○○ -0.36 -0.359615217336321
Escherichia coli M12  CO715_24950  ATI08658.1  157 aa antirestriction protein 1.9e-11 ●○○○○ -0.36 -0.358363341250827
Escherichia coli M12  CO715_02800  ATI04760.1  191 aa GDP-mannose pyrophosphatase NudK 0.0016 ●○○○○ -0.36 -0.357737403208081
Escherichia coli M12  CO715_03735  ATI04930.1  556 aa 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 0.0013 ●○○○○ -0.36 -0.357528757193832
Escherichia coli M12  CO715_09955  ATI06005.1  1293 aa enterobactin synthase subunit F 6.7e-25 ●○○○○ -0.36 -0.357320111179583
Porphyromonas gingivalis ATCC 33277  PGN_0121  WP_012457261.1  B2RGZ5  581 aa hypothetical protein <1e-323 ●○○○○ -0.36 -0.356909584456883
Acinetobacter baumannii ATCC 17978  A1S_1059  ABO11491.1  133 aa putative oligopeptide transport protein 0.045 ●○○○○ -0.36 -0.356853260296448
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2691  AIK81285.1  355 aa efflux transporter, RND family, MFP subunit 2.9e-7 ●○○○○ -0.36 -0.356814022958785
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3317  AIK81874.1  296 aa rbsB 1.4e-7 ●○○○○ -0.36 -0.356767359948546
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2726  AIK81316.1  160 aa transposase, Mutator family protein 0.0011 ●○○○○ -0.36 -0.356354292517846
Escherichia coli M12  CO715_16860  ATI07238.1  166 aa regulatory protein RecX 3.8e-8 ●○○○○ -0.36 -0.35606823509409
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2775  AIK81364.1  299 aa inosose dehydratase 0.0002 ●○○○○ -0.36 -0.355748109526913
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2348  NP_231978.1  Q9KPL9  deoB  406 aa phosphopentomutase 4.6e-5 ●○○○○ -0.36 -0.355490118907826
Escherichia coli M12  CO715_05885  ATI05290.1  859 aa phage tail tape measure protein 2.0e-20 ●○○○○ -0.36 -0.355233651037094
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2369  NP_231999.1  Q9KPJ8  785 aa aerobic respiration control sensor protein ArcB 0.012 ●○○○○ -0.35 -0.354995251117393
Porphyromonas gingivalis ATCC 33277  PGN_1462  WP_012458288.1  B2RKT6  ybeY  151 aa rRNA maturation RNase YbeY 0.022 ●○○○○ -0.35 -0.3545107548168
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1652  NP_231289.1  H9L4Q6  584 aa response regulator VieA 2.7e-5 ●○○○○ -0.35 -0.354365777344114
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2568  AIK81165.1  257 aa hypothetical protein 1.1e-16 ●○○○○ -0.35 -0.353596536832064
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3704  AIK82259.1  811 aa peptidoglycan synthetase penicillin-binding protein 1A <1e-323 ●○○○○ -0.35 -0.3535254006727
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4365  AIK82908.1  390 aa alkanesulfonate monooxygenase, FMNH(2)-dependent 7.8e-11 ●○○○○ -0.35 -0.353164087216092
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2082  AIK80688.1  136 aa cu(I)-responsive transcriptional regulator 4.3e-9 ●○○○○ -0.35 -0.353075984289204
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3157  AIK81729.1  206 aa homoserine/Threonine efflux family protein <1e-323 ●○○○○ -0.35 -0.35169100518383
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1901  AIK80507.1  411 aa bacterial regulatory, Fis family protein 0.0024 ●○○○○ -0.35 -0.351620082694093
Porphyromonas gingivalis ATCC 33277  PGN_1334  WP_039417135.1  B2RKF8  547 aa hypothetical protein <1e-323 ●○○○○ -0.35 -0.351598930691595
Escherichia coli M12  CO715_22005  ATI08169.1  373 aa GDP-mannose 4,6-dehydratase 2.2e-9 ●○○○○ -0.35 -0.350852084737868
Porphyromonas gingivalis ATCC 33277  PGN_0557  WP_012457596.1  B2RI81  hmuR  646 aa TonB-dependent receptor <1e-323 ●○○○○ -0.35 -0.350845812076298
Porphyromonas gingivalis ATCC 33277  PGN_0704  WP_012457713.1  B2RIM8  757 aa TonB-dependent receptor 7.8e-8 ●○○○○ -0.35 -0.350845812076298
Porphyromonas gingivalis ATCC 33277  PGN_0982  WP_070105217.1  B2RJF6  116 aa hypothetical protein 0.02 ●○○○○ -0.35 -0.350845812076298
Porphyromonas gingivalis ATCC 33277  PGN_0982  WP_012457934.1  B2RJF6  305 aa restriction endonuclease 0.02 ●○○○○ -0.35 -0.350845812076298
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0767  NP_230416.1  Q9KTW3  guaB  489 aa inosine 5'-monophosphate dehydrogenase 0.0009 ●○○○○ -0.35 -0.350782541365319
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3277  AIK81838.1  219 aa azlC family protein <1e-323 ●○○○○ -0.35 -0.350750461833205
Escherichia coli M12  CO715_22555  ATI08264.1  188 aa succinate-acetate/proton symporter SatP 2.6e-27 ●○○○○ -0.35 -0.350434792709371
Escherichia coli M12  CO715_01235  ATI04475.1  284 aa L-ribulose-5-phosphate 3-epimerase UlaE 5.2e-5 ●○○○○ -0.35 -0.350434792709371
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0460  NP_232852.1  Q9KMB3  115 aa hypothetical protein 0.00069 ●○○○○ -0.35 -0.349942164849987
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3526  AIK82081.1  74 aa hypothetical protein 0.028 ●○○○○ -0.35 -0.349706838084341
Escherichia coli M12  CO715_19210  ATI07658.1  377 aa phosphoporin PhoE 1.6e-28 ●○○○○ -0.35 -0.349600208652375
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2340  AIK80943.1  351 aa lysM domain protein <1e-323 ●○○○○ -0.35 -0.348710090784181
Retrieved entries 5,901–6,000 out of 36,363 total in 3.9 ms (Link to these results)