Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_02600  ATI04721.1  50 aa hypothetical protein 3.0e-12 ●●●○○ -2.05 -2.05027387079484
Escherichia coli M12  CO715_18385  ATI07513.1  239 aa tRNA (guanosine(46)-N7)-methyltransferase TrmB 4.6e-14 ●●●○○ -2.05 -2.0496479327521
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4250  WP_001519915.1  E8XKD5  240 aa GntR family transcriptional regulator 6.6e-5 ●●●○○ -2.05 -2.04950216449058
Mycobacterium avium subsp. paratuberculosis K10  MAP_0397  AAS02714.1  Q744E4  267 aa hypothetical protein 0.016 ●●●○○ -2.05 -2.04844291127579
Escherichia coli O157:H7 str. EDL933  Z5813  AAG59400.1  264 aa orf, hypothetical protein 0.022 ●●●○○ -2.05 -2.04830321504482
Escherichia coli M12  CO715_02955  ATI04787.1  298 aa N-acetylmuramic acid 6-phosphate etherase 3.7e-13 ●●●○○ -2.05 -2.04818741065235
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0943  NP_230590.1  Q9KTF9  lipA  321 aa lipoyl synthase 1.0e-8 ●●●○○ -2.05 -2.04631781845038
Mycobacterium avium subsp. paratuberculosis K10  MAP_0054c  AAS02371.1  Q744U7  262 aa hypothetical protein 0.016 ●●●○○ -2.04 -2.04304030286617
Escherichia coli O157:H7 str. EDL933  Z5750  AAG59344.1  289 aa orf, hypothetical protein 0.022 ●●●○○ -2.04 -2.0427398489286
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3673  WP_000736973.1  E8XEK9  feoB  772 aa Fe(2+) transporter permease subunit FeoB 4.4e-5 ●●●○○ -2.04 -2.04242265067903
Haemophilus influenzae Rd KW20  HI_1248  NP_439404.1  P44136  322 aa hypothetical protein 0.042 ●●●○○ -2.04 -2.04173540868779
Haemophilus influenzae Rd KW20  HI_1323  NP_439474.1  P44161  matP  148 aa hypothetical protein 0.042 ●●●○○ -2.04 -2.04173540868779
Mycobacterium avium subsp. paratuberculosis K10  MAP_0668  AAS02985.1  Q743B7  426 aa hypothetical protein 0.016 ●●●○○ -2.04 -2.04158679056928
Vibrio parahaemolyticus RIMD 2210633  VP_2845  BAC61108.1  Q87KX9  efp  188 aa elongation factor P 0.043 ●●●○○ -2.04 -2.04071831003534
Escherichia coli M12  CO715_15650  ATI07021.1  457 aa argininosuccinate lyase 1.3e-11 ●●●○○ -2.04 -2.0406761541394
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3165  WP_000383271.1  E8X9J0  kduI  278 aa 5-dehydro-4-deoxy-D-glucuronate isomerase 7.9e-12 ●●●○○ -2.04 -2.03872108543239
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1716  NP_231352.1  Q9KRC6  mukF  445 aa condesin subunit F 3.7e-9 ●●●○○ -2.04 -2.03866437094365
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0198  WP_000938517.1  E8XHY7  hrpB  824 aa ATP-dependent helicase HrpB 1.3e-10 ●●●○○ -2.04 -2.03767250228228
Streptococcus pyogenes M1 5448  SP5448_04100  WP_010922407.1  430 aa 3-phosphoshikimate 1-carboxyvinyltransferase 0.0048 ●●●○○ -2.04 -2.03724859771834
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0374  NP_230028.1  Q9KUY4  pgi  550 aa glucose-6-phosphate isomerase 2.3e-11 ●●●○○ -2.04 -2.03625606704014
Escherichia coli M12  CO715_13210  ATI06581.1  156 aa arginine repressor 4.9e-7 ●●●○○ -2.04 -2.03587729581167
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4742  AIK83277.1  131 aa hypothetical protein 0.00098 ●●●○○ -2.03 -2.03411519288998
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2199  AIK80804.1  38 aa hypothetical protein 1.0e-6 ●●●○○ -2.03 -2.03407038341484
Mycobacterium avium subsp. paratuberculosis K10  MAP_3836c  AAS06386.1  Q73T82  777 aa hypothetical protein 0.017 ●●●○○ -2.03 -2.03392313027714
Acinetobacter baumannii ATCC 17978  A1S_1269  ABO11697.2  527 aa putative allophanate hydrolase subunit 1 and 2 7.8e-31 ●●●○○ -2.03 -2.03384510529731
Escherichia coli M12  CO715_19955  ATI07792.1  784 aa Lon protease 5.5e-13 ●●●○○ -2.03 -2.03337354364069
Escherichia coli M12  CO715_00470  ATI04340.1  155 aa YhcH/YjgK/YiaL family protein 2.8e-5 ●●●○○ -2.03 -2.03337354364069
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4923  AIK83449.1  312 aa 1-phosphofructokinase <1e-323 ●●●○○ -2.03 -2.03271879652973
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0167  WP_000888962.1  E8XHV6  acnB  865 aa bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 0.00011 ●●●○○ -2.03 -2.03271220227749
Escherichia coli M12  CO715_04000  ATI04976.1  225 aa ribulose-phosphate 3-epimerase 2.7e-10 ●●●○○ -2.03 -2.03253895958369
Escherichia coli M12  CO715_04295  ATI05034.1  211 aa thiamine phosphate synthase 2.8e-15 ●●●○○ -2.03 -2.0312870834982
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0366  WP_002868915.1  A0A0H3PAT9  uvrA  941 aa excinuclease ABC subunit UvrA 0.026 ●●●○○ -2.03 -2.03090074218
Escherichia coli O157:H7 str. EDL933  Z3510  AAG57383.1  200 aa protein induced by aluminum 0.023 ●●●○○ -2.03 -2.03071876723549
Vibrio parahaemolyticus RIMD 2210633  VP_0711  BAC58974.1  Q87RR6  561 aa trehalose-6-phosphate hydrolase 0.044 ●●●○○ -2.03 -2.02904083026845
Mycobacterium avium subsp. paratuberculosis K10  MAP_1391c  AAS03708.1  Q740G0  207 aa hypothetical protein 0.017 ●●●○○ -2.03 -2.02894357593373
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0926  WP_002853290.1  A0A0H3PA28  219 aa amino acid ABC transporter permease 0.027 ●●●○○ -2.03 -2.02817716922
Escherichia coli CFT073  c2037  AAN80497.1  A0A0H2V7L5  ydhK  670 aa Hypothetical protein ydhK 0.024 ●●●○○ -2.03 -2.02746009675828
Escherichia coli O157:H7 str. EDL933  Z5136  AAG58848.1  204 aa hypothetical protein 0.023 ●●●○○ -2.03 -2.02732187496741
Escherichia coli M12  CO715_08000  ATI05658.1  355 aa 5-(carboxyamino)imidazole ribonucleotide synthase 1.7e-5 ●●●○○ -2.03 -2.02711416321322
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3883  CBW19973.1  A0A0H3NNE2  rffC  182 aa lipopolysaccharide biosynthesis protein 5.1e-5 ●●●○○ -2.03 -2.02612789420407
Mycobacterium avium subsp. paratuberculosis K10  MAP_4078  AAS06628.1  Q73SJ5  320 aa hypothetical protein 0.017 ●●●○○ -2.03 -2.02586003703819
Haemophilus influenzae Rd KW20  HI_0887  NP_439048.1  P43852  purH  532 aa bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.043 ●●●○○ -2.03 -2.02555435575152
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2911  WP_000274378.1  E8XK18  iroE  311 aa alpha/beta hydrolase 4.4e-6 ●●●○○ -2.02 -2.02443171292986
Escherichia coli CFT073  c2239  AAN80698.1  A0A0H2V7Z4  prc  682 aa Tail-specific protease precursor 0.048 ●●●○○ -2.02 -2.02398755611562
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0859  WP_002861483.1  A0A0H3P9Z2  541 aa lytic transglycosylase domain-containing protein 0.027 ●●●○○ -2.02 -2.02307481381
Escherichia coli O157:H7 str. EDL933  Z4009  AAG57810.1  216 aa PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components; frag 0.023 ●●●○○ -2.02 -2.02257571828341
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0727  NP_230376.1  Q9KU03  236 aa transcriptional regulator PhoU 4.2e-6 ●●●○○ -2.02 -2.02253305084101
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3253  CBW19349.1  A0A0H3NI69  deaD  629 aa ATP-dependent RNA helicase (dead-box protein) 1.2e-5 ●●●○○ -2.02 -2.02209757885468
Escherichia coli M12  CO715_07890  ATI05638.1  120 aa hypothetical protein 4.5e-13 ●●●○○ -2.02 -2.0214807208285
Escherichia coli M12  CO715_07500  ATI05572.1  191 aa NAD(P)H-dependent FMN reductase 1.5e-8 ●●●○○ -2.02 -2.02043749075726
Escherichia coli M12  CO715_17980  ATI07441.1  219 aa hemolysin III family protein 4.6e-6 ●●●○○ -2.02 -2.02043749075726
Streptococcus pyogenes M1 5448  SP5448_01495  WP_011054989.1  427 aa trigger factor 0.048 ●●●○○ -2.02 -2.01898320425511
Escherichia coli M12  CO715_09940  ATI06002.1  330 aa iron-enterobactin transporter permease 1.4e-27 ●●●○○ -2.02 -2.01835103061477
Escherichia coli M12  CO715_05040  ATI05154.1  299 aa ATP phosphoribosyltransferase 1.2e-14 ●●●○○ -2.02 -2.01668186250078
Vibrio parahaemolyticus RIMD 2210633  VP_1168  BAC59431.1  Q87QI1  331 aa peptide ABC transporter, ATP-binding protein 0.046 ●●●○○ -2.01 -2.01392087877154
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1596  NP_231236.2  Q9KRP0  354 aa galactose-1-phosphate uridylyltransferase 3.1e-12 ●●●○○ -2.01 -2.01384519312882
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0092  NP_229751.1  Q9KVP9  lexA  209 aa LexA repressor 4.0e-7 ●●●○○ -2.01 -2.01223989512919
Haemophilus influenzae Rd KW20  HI_1249  NP_439405.1  P44137  206 aa hypothetical protein 0.044 ●●●○○ -2.01 -2.01080436198276
Escherichia coli O157:H7 str. EDL933  Z4492  AAG58270.1  158 aa PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 1 (EIIB-AGA) 0.024 ●●●○○ -2.01 -2.01010187490336
Mycobacterium avium subsp. paratuberculosis K10  MAP_3889  AAS06439.1  Q73T30  165 aa hypothetical protein 0.017 ●●●○○ -2.01 -2.01004857709237
Acinetobacter baumannii ATCC 17978  A1S_2276  ABO12699.2  756 aa hypothetical protein 7.4e-13 ●●●○○ -2.01 -2.00999204707206
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4630  WP_000661783.1  E8XBI6  408 aa MFS transporter 2.3e-13 ●●●○○ -2.01 -2.00930774765967
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0544  WP_000006865.1  E8X8B0  allB  453 aa allantoinase AllB 1.6e-12 ●●●○○ -2.01 -2.00801197122101
Escherichia coli M12  CO715_06480  ATI05392.1  76 aa cation transport regulator ChaB 1.5e-9 ●●●○○ -2.01 -2.00791872990232
Haemophilus influenzae Rd KW20  HI_0480  NP_438640.1  P43716  atpG  289 aa F0F1 ATP synthase subunit gamma 0.045 ●●●○○ -2.01 -2.00783269838906
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4063  CBW20152.1  A0A0H3NV35  pflD  765 aa formate acetyltransferase 2 (ec 2.3.1.54) (pyruvate formate-lyase 2) 0.0009 ●●●○○ -2.01 -2.00768048791312
Escherichia coli M12  CO715_07035  ATI05490.1  233 aa Replication protein P 1.1e-14 ●●●○○ -2.01 -2.00750143787383
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4158  WP_000209831.1  E8XJG8  fre  233 aa NAD(P)H-flavin reductase 0.00037 ●●●○○ -2.01 -2.00743554174611
Vibrio parahaemolyticus RIMD 2210633  VP_2997  BAC61260.1  Q87KI0  ubiD  617 aa conserved hypothetical protein 0.046 ●●●○○ -2.01 -2.0073595246258
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3924  WP_000834259.1  E8XGV0  yicJ  460 aa glycoside-pentoside-hexuronide family transporter 7.5e-13 ●●●○○ -2.01 -2.00726300825794
Streptococcus pyogenes M1 5448  SP5448_07845  WP_010921932.1  79 aa hypothetical protein 0.01 ●●●○○ -2.01 -2.0055244932822
Escherichia coli O157:H7 str. EDL933  Z1328  AAG55461.1  85 aa unknown protein encoded by cryptic prophage CP-933M 0.024 ●●●○○ -2 -2.00499898485874
Acinetobacter baumannii ATCC 17978  A1S_0231  ABO10706.2  394 aa putative periplasmic carboxyl-terminal protease 0.0012 ●●●○○ -2 -2.00440901377979
Vibrio parahaemolyticus RIMD 2210633  VP_0058  BAC58321.1  Q87TL1  369 aa gluconate utilization system Gnt-I transcriptional repressor 0.047 ●●●○○ -2 -2.00284070453488
Mycobacterium avium subsp. paratuberculosis K10  MAP_1667  AAS03984.1  Q73ZD6  271 aa hypothetical protein 0.018 ●●●○○ -2 -2.00279288932662
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4011  AIK82558.1  273 aa undecaprenyl-diphosphatase UppP <1e-323 ●●●○○ -2 -2.0027178246777
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1116  WP_002869044.1  A1W085  pyrB  295 aa aspartate carbamoyltransferase 0.028 ●●●○○ -2 -2.00193873698
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0094  NP_229753.1  Q9KVP7  ubiA  284 aa 4-hydroxybenzoate octaprenyltransferase 4.1e-10 ●●●○○ -2 -2.00191854972126
Mycobacterium avium subsp. paratuberculosis K10  MAP_3557  AAS06107.1  Q73U11  126 aa hypothetical protein 0.018 ●●●○○ -2 -2.00182773853569
Streptococcus pyogenes M1 5448  SP5448_03945  WP_002989220.1  71 aa helix-turn-helix transcriptional regulator 0.0068 ●●●○○ -2 -2.00167914728994
Acinetobacter baumannii ATCC 17978  A1S_1519  ABO11946.2  A3M4V2  metK  388 aa methionine adenosyltransferase 5.7e-9 ●●●○○ -2 -2.00103055268094
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0996  WP_002854139.1  A0A0H3PD47  192 aa hypothetical protein 0.028 ●●●○○ -2 -2.00063174638
Mycobacterium avium subsp. paratuberculosis K10  MAP_0343  AAS02660.1  Q744J8  122 aa hypothetical protein 0.018 ●●●○○ -2 -2.00048407497513
Mycobacterium avium subsp. paratuberculosis K10  MAP_1311  AAS03628.1  Q740N9  tesB1  300 aa TesB1 0.018 ●●●○○ -2 -2.00034632154256
Escherichia coli M12  CO715_13300  ATI06598.1  276 aa hypothetical protein 2.4e-14 ●●○○○ -2 -1.99936424331812
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3276  WP_001147546.1  E8XAH6  124 aa cupin domain-containing protein 3.4e-12 ●●○○○ -2 -1.99871451148767
Escherichia coli M12  CO715_05475  ATI05227.1  251 aa zinc ABC transporter ATP-binding protein ZnuC 9.3e-18 ●●○○○ -2 -1.99811236723263
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2660  CBW18762.1  A0A0H3NER3  smpB  160 aa SsrA (tmRNA)-binding protein 0.0005 ●●○○○ -2 -1.99793994165925
Escherichia coli M12  CO715_03745  ATI04932.1  285 aa 1,4-dihydroxy-2-naphthoyl-CoA synthase 6.8e-11 ●●○○○ -2 -1.99644319911864
Escherichia coli M12  CO715_15150  ATI06933.1  222 aa fimbrial chaperone EcpB 4.2e-11 ●●○○○ -2 -1.99519132303314
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5044  AIK83570.1  434 aa hisD 1.1e-12 ●●○○○ -1.99 -1.99469618293949
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3700  AIK82255.1  133 aa heat shock protein Hsp15 involved in ribosome recycling 1.1e-16 ●●○○○ -1.99 -1.99463655205111
Mycobacterium avium subsp. paratuberculosis K10  MAP_0667  AAS02984.1  Q743B8  72 aa hypothetical protein 0.018 ●●○○○ -1.99 -1.99457861622969
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0056  CBW16157.1  A0A0H3N8V4  591 aa oxaloacetate decarboxylase alpha chain 3.8e-6 ●●○○○ -1.99 -1.99455136408037
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3558  AIK82114.1  338 aa periplasmic binding and sugar binding domain of LacI family protein 6.6e-10 ●●○○○ -1.99 -1.9939275536531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1799  AIK80412.1  115 aa succinate dehydrogenase, hydrophobic membrane anchor protein 0.0073 ●●○○○ -1.99 -1.99346066506293
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2581  WP_000673300.1  E8XFT7  yfeW  432 aa penicillin binding protein PBP4B 3.7e-11 ●●○○○ -1.99 -1.99292594812307
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0250  NP_232648.1  Q9KMS0  466 aa alpha-amylase 9.7e-7 ●●○○○ -1.99 -1.99186521592891
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2895  WP_000088556.1  E8XJC0  291 aa integrase 1.2e-14 ●●○○○ -1.99 -1.99167344150639
Acinetobacter baumannii ATCC 17978  A1S_0052  ABO10547.2  431 aa WecC protein 0.018 ●●○○○ -1.99 -1.99143519863956
Retrieved entries 1,701–1,800 out of 36,363 total in 575 ms (Link to these results)