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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5044  AIK83570.1  434 aa hisD 1.1e-12 ●●○○○ -1.99 -1.99469618293949
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3700  AIK82255.1  133 aa heat shock protein Hsp15 involved in ribosome recycling 1.1e-16 ●●○○○ -1.99 -1.99463655205111
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3558  AIK82114.1  338 aa periplasmic binding and sugar binding domain of LacI family protein 6.6e-10 ●●○○○ -1.99 -1.9939275536531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1799  AIK80412.1  115 aa succinate dehydrogenase, hydrophobic membrane anchor protein 0.0073 ●●○○○ -1.99 -1.99346066506293
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3293  AIK81854.1  607 aa GTP-binding protein TypA/BipA <1e-323 ●●○○○ -1.97 -1.97217797020214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3493  AIK82049.1  55 aa ribosomal protein L33 1.1e-7 ●●○○○ -1.97 -1.96935760279367
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3530  AIK82086.1  462 aa L-seryl-tRNA selenium transferase <1e-323 ●●○○○ -1.97 -1.96867257777206
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4837  AIK83364.1  119 aa NADH:ubiquinone oxidoreductase, membrane subunitA 0.012 ●●○○○ -1.96 -1.95731940382212
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3160  AIK81732.1  154 aa hypothetical protein 5.5e-15 ●●○○○ -1.95 -1.94711706322256
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1964  AIK80570.1  213 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein 3.0e-6 ●●○○○ -1.95 -1.94658361247786
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4259  AIK82805.1  331 aa periplasmic binding and sugar binding domain of LacI family protein 1.2e-9 ●●○○○ -1.93 -1.92767087049286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5060  AIK83586.1  129 aa malonate semialdehyde decarboxylase 0.0018 ●●○○○ -1.9 -1.90348634564569
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3203  AIK81772.1  495 aa threonine ammonia-lyase, biosynthetic <1e-323 ●●○○○ -1.9 -1.90184902772316
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4049  AIK82596.1  141 aa tonB system transport protein ExbD 2.5e-7 ●●○○○ -1.9 -1.89824830218754
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2570  AIK81167.1  426 aa threonine synthase <1e-323 ●●○○○ -1.89 -1.88698546896814
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4846  AIK83373.1  100 aa NADH:ubiquinone oxidoreductase, membrane subunitK 0.00043 ●●○○○ -1.89 -1.88624241373225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4743  AIK83276.1  303 aa cysteine synthase B 0.00098 ●●○○○ -1.89 -1.8853856296457
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3224  AIK81785.1  210 aa fabR transcriptional repressor FabR transcriptional dual regulator 4.2e-12 ●●○○○ -1.88 -1.88097545291029
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1691  AIK80311.1  240 aa glnQ <1e-323 ●●○○○ -1.88 -1.87933681990934
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2735  AIK81325.1  331 aa hypothetical protein 3.0e-6 ●●○○○ -1.88 -1.87710829108431
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2460  AIK81057.1  297 aa nicotinate-nucleotide diphosphorylase 8.6e-9 ●●○○○ -1.87 -1.8677525231417
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1665  AIK80285.1  619 aa nickel import ATP-binding protein NikE 0.039 ●●○○○ -1.87 -1.86650898366657
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1458  AIK80079.1  185 aa DNA-binding transcriptional repressor 0.021 ●●○○○ -1.86 -1.86107526504709
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4545  AIK83083.1  268 aa bacterial extracellular solute-binding, 3 familyprotein 1.6e-9 ●●○○○ -1.85 -1.85384928079492
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2559  AIK81156.1  377 aa chaperone protein DnaJ 3.2e-5 ●●○○○ -1.85 -1.84907791241932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3626  AIK82181.1  300 aa putative 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD <1e-323 ●●○○○ -1.84 -1.84222548309787
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3630  AIK82184.1  126 aa arnF <1e-323 ●●○○○ -1.84 -1.84214130641482
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3271  AIK81832.1  382 aa lactaldehyde reductase <1e-323 ●●○○○ -1.82 -1.81971336413785
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4125  AIK82671.1  663 aa transketolase 0.013 ●●○○○ -1.8 -1.80093813984857
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3590  AIK82145.1  639 aa putative zinc-dependent peptidase 3.8e-11 ●●○○○ -1.79 -1.79457275415617
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1742  AIK80362.1  143 aa universal stress protein UP12 2.3e-5 ●●○○○ -1.79 -1.78520294741972
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3861  AIK82411.1  90 aa phosphocarrier, HPr family protein 7.2e-13 ●●○○○ -1.78 -1.78359494815035
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4843  AIK83370.1  325 aa NADH:ubiquinone oxidoreductase, membrane subunitH 0.013 ●●○○○ -1.78 -1.77771773998676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4601  AIK83136.1  539 aa L-aspartate oxidase <1e-323 ●●○○○ -1.77 -1.77188296769045
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1573  AIK80193.1  73 aa cold shock domain protein CspD 0.00027 ●●○○○ -1.77 -1.77105179780836
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3266  AIK81827.1  276 aa rhamnulose-1-phosphate aldolase 1.2e-15 ●●○○○ -1.76 -1.75973723009172
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3680  AIK82235.1  109 aa thiosulfate:cyanide sulfurtransferase 1.3e-5 ●●○○○ -1.75 -1.74794707407623
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4466  AIK83009.1  175 aa putative electron transport protein HydN 8.7e-10 ●●○○○ -1.73 -1.72997824922223
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1594  AIK80214.1  222 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein <1e-323 ●●○○○ -1.73 -1.72870993425433
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1260  AIK79883.1  114 aa HNH endonuclease family protein <1e-323 ●●○○○ -1.72 -1.72102456203238
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3541  AIK82097.1  484 aa xylulokinase <1e-323 ●●○○○ -1.71 -1.70712770307192
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3853  AIK82403.1  1448 aa glutamate synthase (NADPH) large chain glutamatesynthase, large subunit <1e-323 ●●○○○ -1.7 -1.69623696213403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3167  AIK81739.1  274 aa diaminopimelate epimerase 0.021 ●●○○○ -1.69 -1.6883299533522
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3464  AIK82020.1  188 aa hypothetical protein 1.3e-10 ●●○○○ -1.67 -1.67230690705897
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2981  AIK81566.1  335 aa pfkB carbohydrate kinase family protein 2.1e-11 ●●○○○ -1.67 -1.66733642077406
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3284  AIK81845.1  211 aa formate dehydrogenase, gamma subunit <1e-323 ●●○○○ -1.65 -1.65398991748504
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1654  AIK80274.1  252 aa deoR-like helix-turn-helix domain protein 0.0063 ●●○○○ -1.65 -1.64716215003351
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1453  AIK80074.1  73 aa hypothetical protein 0.0018 ●●○○○ -1.63 -1.63287853016129
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4505  AIK83043.1  111 aa ygaH L-valine exporter 1.0e-7 ●●○○○ -1.63 -1.63143636757052
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2778  AIK81367.1  646 aa 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase 0.00049 ●●○○○ -1.63 -1.63085375320251
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4458  AIK83001.1  255 aa hydrogenase 3 and formate hydrogenlyase complex,HycG subunit 0.00038 ●●○○○ -1.63 -1.62980496457023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2509  AIK81105.1  233 aa thiamine ABC transporter, ATP-binding protein 1.5e-10 ●●○○○ -1.62 -1.62255671428573
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2273  AIK80878.1  173 aa transposase family protein 1.4e-6 ●●○○○ -1.62 -1.62050095250413
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3842  AIK82392.1  236 aa ATP:dephospho-CoA triphosphoribosyl transferase family protein 1.9e-11 ●●○○○ -1.61 -1.61158067454457
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4442  AIK82985.1  423 aa PTS system, lactose/cellobiose IIC component family protein 0.0088 ●●○○○ -1.61 -1.60792535105998
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4672  AIK83206.1  73 aa addiction module antidote protein, HigA family 5.2e-6 ●●○○○ -1.6 -1.60368542594075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2404  AIK81001.1  185 aa putative general secretion pathway protein B <1e-323 ●●○○○ -1.6 -1.59931518776291
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4284  AIK82829.1  231 aa DNA mismatch repair endonuclease MutH <1e-323 ●●○○○ -1.6 -1.59812057727736
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3594  AIK82149.1  61 aa putative antibiotic biosynthesis monooxygenase 8.4e-11 ●●○○○ -1.59 -1.59228442614906
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2914  AIK81500.1  120 aa fumarate reductase membrane protein <1e-323 ●●○○○ -1.59 -1.59096408796701
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2420  AIK81017.1  809 aa ATP-dependent helicase HrpB 2.4e-9 ●●○○○ -1.59 -1.58628585819714
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3256  AIK81817.1  87 aa LTXXQ motif family protein <1e-323 ●●○○○ -1.58 -1.58463556200493
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3662  AIK82217.1  106 aa hypothetical protein <1e-323 ●●○○○ -1.58 -1.58203182623292
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4550  AIK83088.1  142 aa transcriptional regulator family protein 3.2e-11 ●●○○○ -1.58 -1.5818588205683
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3069  AIK81654.1  164 aa manX <1e-323 ●●○○○ -1.57 -1.56681988958594
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4504  AIK83042.1  176 aa emrR transcriptional repressor MprA transcriptional repressor <1e-323 ●●○○○ -1.56 -1.56472897180277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3163  AIK81735.1  720 aa DNA helicase II <1e-323 ●●○○○ -1.56 -1.55976481621001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4131  AIK82677.1  239 aa hypothetical protein <1e-323 ●●○○○ -1.55 -1.55413483259328
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4196  AIK82741.1  359 aa ammonium Transporter family protein <1e-323 ●●○○○ -1.55 -1.55263800351945
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3290  AIK81851.1  131 aa D-tyrosyl-tRNA(Tyr) deacylase 4.9e-10 ●●○○○ -1.55 -1.55026281050013
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4533  AIK83071.1  364 aa fimbrial family protein 0.006 ●●○○○ -1.54 -1.54388592651713
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2892  AIK81481.1  420 aa hflK protein <1e-323 ●●○○○ -1.53 -1.53265170713172
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3207  AIK81775.1  52 aa ACT domain protein <1e-323 ●●○○○ -1.53 -1.52932220544903
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2890  AIK81479.1  96 aa hypothetical protein 4.2e-9 ●●○○○ -1.53 -1.52906550195443
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3067  AIK81652.1  267 aa short chain dehydrogenase family protein 2.1e-10 ●●○○○ -1.52 -1.52101267400929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2845  AIK81434.1  66 aa hypothetical protein 0.00073 ●●○○○ -1.52 -1.51856229558897
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3873  AIK82423.1  260 aa mlaE <1e-323 ●●○○○ -1.51 -1.51467339789729
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1516  AIK80136.1  381 aa alkanesulfonate monooxygenase, FMNH(2)-dependent 3.0e-9 ●●○○○ -1.5 -1.5007083277195
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4473  AIK83015.1  516 aa norR transcriptional activator NorR transcriptional dual regulator <1e-323 ●●○○○ -1.49 -1.4903918123749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2272  AIK80877.1  261 aa putative transposase 0.006 ●●○○○ -1.49 -1.48529792262384
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2392  AIK80989.1  266 aa periplasmic vitamin B12 binding protein 0.0013 ●●○○○ -1.48 -1.47507903095526
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4792  AIK83319.1  183 aa smr domain protein 0.0004 ●●○○○ -1.47 -1.47135257485123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4983  AIK83509.1  455 aa mannitol dehydrogenase Rossmann domain protein 1.3e-10 ●●○○○ -1.47 -1.46563541305326
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3962  AIK82510.1  344 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●●○○○ -1.47 -1.46551604610278
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2704  AIK81294.1  227 aa transcriptional activator protein CopR <1e-323 ●●○○○ -1.47 -1.4653459829708
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3412  AIK81969.1  313 aa bacterial regulatory, lacI family protein <1e-323 ●●○○○ -1.46 -1.4647588450815
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3243  AIK81804.1  386 aa O-succinylhomoserine (thiol)-lyase <1e-323 ●●○○○ -1.46 -1.45862410251774
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4142  AIK82688.1  364 aa glycine cleavage system T protein 2.9e-10 ●●○○○ -1.46 -1.45806312044684
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3932  AIK82480.1  50 aa hypothetical protein <1e-323 ●●○○○ -1.46 -1.4560982298401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4362  AIK82905.1  251 aa 5'-3' exonuclease, C-terminal SAM fold family protein 0.0042 ●●○○○ -1.45 -1.4539637581388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5113  AIK83639.1  37 aa hemolysin expression modulating family protein <1e-323 ●●○○○ -1.45 -1.45392822111739
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4922  AIK83448.1  376 aa phosphocarrier, HPr family protein 0.0018 ●●○○○ -1.45 -1.44907846283614
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3440  AIK81997.1  259 aa beta-lactamase superfamily domain protein 3.2e-10 ●●○○○ -1.45 -1.44859601331806
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2152  AIK80757.1  784 aa ATP-dependent protease La 2.2e-16 ●●○○○ -1.45 -1.44639893989232
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3943  AIK82491.1  122 aa hypothetical protein <1e-323 ●●○○○ -1.44 -1.43867071549681
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4818  AIK83345.1  257 aa hisP 0.0074 ●●○○○ -1.44 -1.43614688089645
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2964  AIK81549.1  92 aa phnA family protein 1.1e-6 ●●○○○ -1.44 -1.43529236239746
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1609  AIK80229.1  87 aa glutaredoxin, GrxA family 0.0013 ●●○○○ -1.43 -1.43365654117661
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2968  AIK81553.1  194 aa phosphonate C-P lyase system protein PhnH 4.3e-14 ●●○○○ -1.43 -1.42882249311136
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5035  AIK83561.1  297 aa glycosyl transferase 2 family protein 3.5e-5 ●●○○○ -1.42 -1.42384568801583
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