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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Mycobacterium avium subsp. paratuberculosis K10  MAP_1239c  AAS03556.1  Q740V3  mmpL4  972 aa MmpL4_2 0.042 ●●○○○ -1.5 -1.50454218371778
Escherichia coli M12  CO715_23490  ATI08412.1  67 aa hypothetical protein 1.3e-9 ●●○○○ -1.5 -1.50403860549132
Escherichia coli M12  CO715_21615  ATI08095.1  571 aa D-lactate dehydrogenase 0.04 ●●○○○ -1.5 -1.50403860549132
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1141  NP_230786.1  Q9KSW5  741 aa isocitrate dehydrogenase 3.3e-7 ●●○○○ -1.5 -1.50365431845007
Escherichia coli M12  CO715_13215  ATI06582.1  87 aa hypothetical protein 1.4e-41 ●●○○○ -1.5 -1.50341266744858
Escherichia coli M12  CO715_13760  ATI06678.1  128 aa cytochrome b562 3.3e-7 ●●○○○ -1.5 -1.50278672940583
Escherichia coli M12  CO715_13780  ATI06682.1  332 aa fructose 1,6-bisphosphatase 0.0028 ●●○○○ -1.5 -1.50236943737733
Mycobacterium avium subsp. paratuberculosis K10  MAP_0028c  AAS02345.1  Q741E1  411 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.50202466294846
Mycobacterium avium subsp. paratuberculosis K10  MAP_1150c  AAS03467.1  Q741E1  411 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.50179314163642
Mycobacterium avium subsp. paratuberculosis K10  MAP_0849c  AAS03166.1  Q742I6  411 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.50158716578305
Acinetobacter baumannii ATCC 17978  A1S_0259  ABO10734.1  A3M1E0  argH  344 aa argininosuccinate lyase 2.1e-12 ●●○○○ -1.5 -1.50120910678282
Escherichia coli M12  CO715_07640  ATI05599.1  328 aa ABC transporter ATP-binding protein 4.0e-5 ●●○○○ -1.5 -1.50111756129184
Mycobacterium avium subsp. paratuberculosis K10  MAP_1751  AAS04068.1  Q73Z52  389 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.50101153278381
Mycobacterium avium subsp. paratuberculosis K10  MAP_1053  AAS03370.1  Q741N7  419 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.50095944801016
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1516  AIK80136.1  381 aa alkanesulfonate monooxygenase, FMNH(2)-dependent 3.0e-9 ●●○○○ -1.5 -1.5007083277195
Escherichia coli M12  CO715_09915  ATI05997.1  536 aa 2,3-dihydroxybenzoate-AMP ligase 6.9e-41 ●●○○○ -1.5 -1.5000743312206
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3693  WP_000448179.1  E8XEM9  glpD  502 aa glycerol-3-phosphate dehydrogenase 2.1e-7 ●●○○○ -1.5 -1.50006731592869
Mycobacterium avium subsp. paratuberculosis K10  MAP_3759c  AAS06309.1  Q742I6  411 aa hypothetical protein 0.042 ●●○○○ -1.5 -1.49994171859006
Escherichia coli M12  CO715_19265  ATI07667.1  481 aa amidohydrolase 2.1e-15 ●●○○○ -1.5 -1.4992397471636
Acinetobacter baumannii ATCC 17978  A1S_2233  ABO12660.1  277 aa hypothetical protein 4.0e-9 ●●○○○ -1.5 -1.49908804329112
Mycobacterium avium subsp. paratuberculosis K10  MAP_3733c  AAS06283.1  Q73TI5  208 aa hypothetical protein 0.043 ●●○○○ -1.5 -1.49884920766784
Escherichia coli M12  CO715_04690  ATI05094.1  261 aa flagellar type III secretion system protein FliR 2.6e-29 ●●○○○ -1.5 -1.49861380912085
Escherichia coli M12  CO715_12920  ATI06530.1  97 aa ribosome assembly RNA-binding protein YhbY 0.0027 ●●○○○ -1.5 -1.49757057904961
Mycobacterium avium subsp. paratuberculosis K10  MAP_2081  AAS04398.1  Q73Y76  558 aa hypothetical protein 0.043 ●●○○○ -1.5 -1.49731231318086
Mycobacterium avium subsp. paratuberculosis K10  MAP_3877c  AAS06427.1  Q73T42  fadE20  382 aa FadE20_3 0.043 ●●○○○ -1.5 -1.49716830648462
Escherichia coli M12  CO715_00765  ATI04394.1  120 aa hypothetical protein 0.041 ●●○○○ -1.5 -1.49715328702111
Acinetobacter baumannii ATCC 17978  A1S_1066  ABO11497.2  A3M3K3  pyrC  344 aa dihydroorotase 2.6e-6 ●●○○○ -1.5 -1.49637965762763
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2897  WP_001738699.1  E8XJC2  198 aa DUF4102 domain-containing protein 1.1e-5 ●●○○○ -1.5 -1.49636267270369
Escherichia coli M12  CO715_20480  ATI07891.1  419 aa cytosine permease 5.3e-32 ●●○○○ -1.5 -1.49611005694987
Escherichia coli M12  CO715_09785  ATI05974.1  226 aa response regulator 1.3e-17 ●●○○○ -1.5 -1.49590141093562
Acinetobacter baumannii ATCC 17978  A1S_0146  ABO10629.2  267 aa high affinity Zn transport protein 6.7e-8 ●●○○○ -1.5 -1.49570368628323
Escherichia coli M12  CO715_16900  ATI07246.1  119 aa transcriptional regulator GutM 9.8e-9 ●●○○○ -1.49 -1.49402359680738
Escherichia coli M12  CO715_03175  ATI04825.1  412 aa alanine transaminase 2.7e-8 ●●○○○ -1.49 -1.49318901275038
Escherichia coli M12  CO715_19895  ATI07780.1  428 aa ammonia channel 4.0e-21 ●●○○○ -1.49 -1.49298036673613
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2203  NP_231834.1  Q9KQ04  255 aa flagellar basal body P-ring biosynthesis protein FlgA 2.4e-7 ●●○○○ -1.49 -1.4928429414623
Escherichia coli M12  CO715_00930  ATI04422.1  454 aa tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 6.9e-7 ●●○○○ -1.49 -1.49277172072189
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4383  WP_000954611.1  E8X8V1  yjbC  289 aa 23S rRNA pseudouridine(2604) synthase RluF 6.2e-5 ●●○○○ -1.49 -1.49274117228506
Escherichia coli M12  CO715_10505  ATI06091.1  390 aa pyridoxal phosphate-dependent aminotransferase 1.2e-14 ●●○○○ -1.49 -1.49235442869339
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4752  WP_000431550.1  E8XCJ4  bglJ  224 aa DNA-binding transcriptional activator BglJ 6.3e-10 ●●○○○ -1.49 -1.4916086216568
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4473  AIK83015.1  516 aa norR transcriptional activator NorR transcriptional dual regulator <1e-323 ●●○○○ -1.49 -1.4903918123749
Mycobacterium avium subsp. paratuberculosis K10  MAP_0779  AAS03096.1  Q742Q6  396 aa hypothetical protein 0.043 ●●○○○ -1.49 -1.48951477007182
Mycobacterium avium subsp. paratuberculosis K10  MAP_2154c  AAS04471.1  Q73Y04  191 aa hypothetical protein 0.043 ●●○○○ -1.49 -1.48949310910113
Escherichia coli M12  CO715_09525  ATI05931.1  87 aa hypothetical protein 5.1e-6 ●●○○○ -1.49 -1.4894333844939
Mycobacterium avium subsp. paratuberculosis K10  MAP_2367c  AAS04684.1  Q73XE2  634 aa hypothetical protein 0.043 ●●○○○ -1.49 -1.48942331895704
Acinetobacter baumannii ATCC 17978  A1S_1628  ABO12055.2  A3M561  hscA  619 aa heat shock protein 1.1e-8 ●●○○○ -1.49 -1.48925960194364
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4255  WP_001283048.1  E8XKE0  ydeW  319 aa transcriptional regulator LsrR 0.0031 ●●○○○ -1.49 -1.48793021109569
Escherichia coli M12  CO715_05645  ATI05255.1  110 aa head decoration protein 0.0077 ●●○○○ -1.49 -1.48776421637991
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1156  WP_000872773.1  E8XES9  solA  372 aa N-methyl-L-tryptophan oxidase 0.0073 ●●○○○ -1.49 -1.4870964492316
Mycobacterium avium subsp. paratuberculosis K10  MAP_1860  AAS04177.1  Q73YU5  300 aa hypothetical protein 0.043 ●●○○○ -1.49 -1.48551933437739
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2272  AIK80877.1  261 aa putative transposase 0.006 ●●○○○ -1.49 -1.48529792262384
Escherichia coli M12  CO715_18580  ATI07545.1  508 aa PTS glucose transporter subunit IIABC 2.5e-87 ●●○○○ -1.49 -1.48526046420893
Mycobacterium avium subsp. paratuberculosis K10  MAP_1282c  AAS03599.1  Q740R0  615 aa hypothetical protein 0.043 ●●○○○ -1.49 -1.48524086915649
Escherichia coli M12  CO715_19585  ATI07727.1  252 aa YciK family oxidoreductase 5.6e-6 ●●○○○ -1.48 -1.48484317218043
Mycobacterium avium subsp. paratuberculosis K10  MAP_3347c  AAS05897.1  Q73UL9  473 aa hypothetical protein 0.043 ●●○○○ -1.48 -1.48466501814134
Escherichia coli M12  CO715_15935  ATI07069.1  162 aa transcription/translation regulatory transformer protein RfaH 0.041 ●●○○○ -1.48 -1.48463452616618
Escherichia coli M12  CO715_16510  ATI07176.1  428 aa FAD-dependent oxidoreductase 0.0012 ●●○○○ -1.48 -1.48317400406644
Acinetobacter baumannii ATCC 17978  A1S_2085  ABO12512.2  227 aa putative oxidoreductase short-chain dehydrogenase/reductase family 0.00085 ●●○○○ -1.48 -1.48175190383652
Escherichia coli M12  CO715_02610  ATI04723.1  513 aa exopolyphosphatase 3.0e-11 ●●○○○ -1.48 -1.48067025189545
Escherichia coli M12  CO715_05085  ATI05161.1  157 aa DNA gyrase inhibitor SbmC 2.7e-35 ●●○○○ -1.48 -1.4804616058812
Escherichia coli M12  CO715_15930  ATI07068.1  260 aa 3'-5' ssDNA/RNA exonuclease TatD 2.7e-26 ●●○○○ -1.48 -1.48025295986695
Mycobacterium avium subsp. paratuberculosis K10  MAP_2632c  AAS04949.1  Q73WM8  121 aa hypothetical protein 0.044 ●●○○○ -1.48 -1.47987977264029
Mycobacterium avium subsp. paratuberculosis K10  MAP_2882c  AAS05199.1  Q73VX9  353 aa hypothetical protein 0.044 ●●○○○ -1.48 -1.47956397629707
Escherichia coli M12  CO715_08185  ATI05693.1  427 aa 3-phosphoshikimate 1-carboxyvinyltransferase 0.042 ●●○○○ -1.48 -1.47941837580996
Escherichia coli M12  CO715_22245  ATI08213.1  246 aa lipopolysaccharide N-acetylmannosaminouronosyltransferase 1.5e-23 ●●○○○ -1.48 -1.47920972979571
Mycobacterium avium subsp. paratuberculosis K10  MAP_1609c  AAS03926.1  Q73ZJ4  fbpB  330 aa FbpB 0.044 ●●○○○ -1.48 -1.47914433414988
Escherichia coli M12  CO715_22560  ATI08265.1  195 aa molybdopterin adenylyltransferase 7.0e-19 ●●○○○ -1.48 -1.47900108378146
Escherichia coli M12  CO715_04660  ATI05089.1  564 aa cellulose biosynthesis regulator YedQ 1.2e-17 ●●○○○ -1.48 -1.47900108378146
Escherichia coli M12  CO715_07100  ATI05503.1  226 aa exonuclease 8.1e-14 ●●○○○ -1.48 -1.47900108378146
Escherichia coli M12  CO715_16465  ATI07167.1  329 aa 4-hydroxythreonine-4-phosphate dehydrogenase 7.0e-11 ●●○○○ -1.48 -1.47879243776721
Escherichia coli M12  CO715_06725  ATI05436.1  139 aa protein UmuD 2.0e-6 ●●○○○ -1.48 -1.47879243776721
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3016  WP_000558928.1  E8XL05  iagB  160 aa SPI-1 type III secretion system invasion protein IagB 0.00066 ●●○○○ -1.48 -1.47843180304983
Acinetobacter baumannii ATCC 17978  A1S_0747  ABO11187.2  944 aa ribonucleoside diphosphate reductase alpha subunit 1.5e-5 ●●○○○ -1.48 -1.47790226502222
Mycobacterium avium subsp. paratuberculosis K10  MAP_1383c  AAS03700.1  Q740G8  340 aa hypothetical protein 0.044 ●●○○○ -1.48 -1.47658354783733
Escherichia coli M12  CO715_21725  ATI08116.1  93 aa DUF2574 domain-containing protein 1.9e-55 ●●○○○ -1.48 -1.47628868559623
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0363  WP_000722978.1  E8XJP7  119 aa DUF4156 domain-containing protein 9.6e-10 ●●○○○ -1.48 -1.47625067861912
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2392  AIK80989.1  266 aa periplasmic vitamin B12 binding protein 0.0013 ●●○○○ -1.48 -1.47507903095526
Escherichia coli M12  CO715_24560  ATI08603.1  417 aa gamma-glutamyl-phosphate reductase 8.0e-19 ●●○○○ -1.47 -1.47461951748224
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2651  WP_000174944.1  E8XGN8  292 aa alpha/beta hydrolase 4.7e-8 ●●○○○ -1.47 -1.47453621247523
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3173  WP_000336259.1  E8X9J8  170 aa CaiF/GrlA family transcriptional regulator 1.3e-7 ●●○○○ -1.47 -1.47411412125857
Escherichia coli M12  CO715_05815  ATI05283.1  140 aa phage minor tail protein G 0.043 ●●○○○ -1.47 -1.47378493342524
Mycobacterium avium subsp. paratuberculosis K10  MAP_3255  AAS05803.1  Q73UW1  597 aa hypothetical protein 0.044 ●●○○○ -1.47 -1.4730687881519
Mycobacterium avium subsp. paratuberculosis K10  MAP_3352c  AAS05902.1  Q73UL4  523 aa hypothetical protein 0.044 ●●○○○ -1.47 -1.47303632109235
Escherichia coli M12  CO715_05750  ATI05273.1  117 aa phage tail protein 1.2e-7 ●●○○○ -1.47 -1.47253305733975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4792  AIK83319.1  183 aa smr domain protein 0.0004 ●●○○○ -1.47 -1.47135257485123
Escherichia coli M12  CO715_04100  ATI04996.1  187 aa aminodeoxychorismate synthase component 2 4.0e-27 ●●○○○ -1.47 -1.47107253524
Escherichia coli M12  CO715_16385  ATI07153.1  327 aa thiamine ABC transporter substrate binding subunit 6.5e-15 ●●○○○ -1.47 -1.47065524321151
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2074  CBW18170.1  A0A0H3NDB8  rfbB  361 aa dTDP-glucose 4,6-dehydratase 0.0032 ●●○○○ -1.47 -1.46941598041964
Escherichia coli M12  CO715_21940  ATI08157.1  213 aa uridine kinase 4.6e-22 ●●○○○ -1.47 -1.46940336712601
Mycobacterium avium subsp. paratuberculosis K10  MAP_2010  AAS04327.1  Q73YE6  355 aa hypothetical protein 0.044 ●●○○○ -1.47 -1.46940258825026
Escherichia coli M12  CO715_15315  ATI06962.1  84 aa hypothetical protein 2.5e-9 ●●○○○ -1.47 -1.46898607509752
Escherichia coli M12  CO715_18300  ATI07496.1  243 aa ribosomal RNA small subunit methyltransferase E 2.7e-13 ●●○○○ -1.47 -1.46815149104052
Escherichia coli CFT073  c1836  AAN80299.1  A0A0H2V781  ynbC  585 aa Hypothetical protein ynbC 0.027 ●●○○○ -1.47 -1.46750124325595
Escherichia coli M12  CO715_11520  ATI06279.1  59 aa YoaH family protein 2.1e-6 ●●○○○ -1.47 -1.46731690698353
Mycobacterium avium subsp. paratuberculosis K10  MAP_1826c  AAS04143.1  Q73YX7  263 aa hypothetical protein 0.045 ●●○○○ -1.47 -1.46686369592232
Acinetobacter baumannii ATCC 17978  A1S_2378  ABO12797.1  232 aa putative ABC transporter 2.4e-8 ●●○○○ -1.47 -1.46676276071501
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1369  WP_000612921.1  E8XGH0  ydiJ  1018 aa FAD-binding oxidoreductase 3.9e-9 ●●○○○ -1.47 -1.46663018435585
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3834  WP_000459827.1  E8XFX6  xylR  392 aa xylose operon transcription regulator XylR 4.9e-8 ●●○○○ -1.47 -1.46589611481971
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4983  AIK83509.1  455 aa mannitol dehydrogenase Rossmann domain protein 1.3e-10 ●●○○○ -1.47 -1.46563541305326
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3962  AIK82510.1  344 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●●○○○ -1.47 -1.46551604610278
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2704  AIK81294.1  227 aa transcriptional activator protein CopR <1e-323 ●●○○○ -1.47 -1.4653459829708
Retrieved entries 2,801–2,900 out of 36,363 total in 889.5 ms (Link to these results)