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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0734  NP_230383.1  Q9KTZ6  556 aa malate synthase 0.0092 ○○○○○ 0.75 0.746169274632578
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1896  AIK80502.1  313 aa pfkB carbohydrate kinase family protein 0.00091 ○○○○○ 0.75 0.74637967343977
Escherichia coli M12  CO715_12630  ATI06476.1  381 aa glycerate 2-kinase 0.015 ○○○○○ 0.75 0.746834596225391
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2613  NP_232241.1  Q9KNW7  289 aa phosphoribulokinase 0.00025 ○○○○○ 0.75 0.746987971317117
Escherichia coli M12  CO715_18285  ATI07493.1  464 aa galactose-proton symporter 6.4e-7 ○○○○○ 0.75 0.747251888253888
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1936  AIK80542.1  313 aa periplasmic binding and sugar binding domain of LacI family protein 1.3e-11 ○○○○○ 0.75 0.747342518597652
Escherichia coli M12  CO715_03830  ATI04946.1  693 aa 4-alpha-glucanotransferase 0.0042 ○○○○○ 0.75 0.748086472310884
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4263  AIK82808.1  478 aa sucrose-6-phosphate hydrolase <1e-323 ○○○○○ 0.75 0.748312410049403
Escherichia coli M12  CO715_15310  ATI06961.1  1016 aa formate dehydrogenase O subunit alpha, selenocysteine-containing 8.3e-6 ○○○○○ 0.75 0.748712410353631
Escherichia coli M12  CO715_22340  ATI08229.1  200 aa DNA-binding response regulator 0.0024 ○○○○○ 0.75 0.748712410353631
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1934  NP_231568.1  Q9KQR4  655 aa GGDEF family protein 0.0027 ○○○○○ 0.75 0.748945331671898
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2097  NP_231729.1  Q9KQA3  257 aa esterase 0.00058 ○○○○○ 0.75 0.749047090116473
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4694  AIK83228.1  487 aa peptidase M48 family protein 1.1e-8 ○○○○○ 0.75 0.749124064823346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3991  AIK82539.1  121 aa hdeA/HdeB family protein 1.1e-16 ○○○○○ 0.75 0.750078474804559
Acinetobacter baumannii ATCC 17978  A1S_1946  ABO12373.2  315 aa 1-phosphofructokinase 0.027 ○○○○○ 0.75 0.750450790717032
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0166  NP_232566.1  Q9KN00  cspA  70 aa cold shock transcriptional regulator CspA 0.0023 ○○○○○ 0.75 0.750981589257806
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0059  NP_229718.1  Q9KVT0  46 aa hypothetical protein 0.00025 ○○○○○ 0.75 0.751154533040769
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2166  AIK80771.1  252 aa bacterial transcriptional regulator family protein 2.2e-16 ○○○○○ 0.75 0.751269379847968
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0418  NP_230072.1  Q9KUU7  205 aa Maf-like protein 0.021 ○○○○○ 0.75 0.751732846628575
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0886  NP_230533.1  Q9KTL6  345 aa hypothetical protein 0.0087 ○○○○○ 0.75 0.752076551324776
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2087  AIK80692.1  550 aa calcineurin-like phosphoesterase family protein <1e-323 ○○○○○ 0.75 0.752298943921118
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2657  WP_000982961.1  E8XGP4  csiE  425 aa stationary phase inducible protein CsiE 0.042 ○○○○○ 0.75 0.752611116075345
Escherichia coli M12  CO715_08040  ATI05666.1  381 aa glycerate kinase 2.0e-5 ○○○○○ 0.75 0.753928560709852
Escherichia coli M12  CO715_23665  ATI08442.1  253 aa porin thermoregulatory protein EnvY 7.5e-5 ○○○○○ 0.75 0.753928560709852
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3020  AIK81605.1  524 aa tannase and feruloyl esterase family protein <1e-323 ○○○○○ 0.75 0.753981870181787
Escherichia coli M12  CO715_08520  ATI05753.1  240 aa oxygen-insensitive NADPH nitroreductase 0.012 ○○○○○ 0.75 0.754137206724101
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4774  AIK83302.1  278 aa glucokinase <1e-323 ○○○○○ 0.75 0.754255167381902
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4680  AIK83214.1  295 aa bacterial regulatory helix-turn-helix, lysR family protein 0.0092 ○○○○○ 0.75 0.754262504161798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4405  AIK82948.1  108 aa hypothetical protein <1e-323 ○○○○○ 0.75 0.75427095095099
Acinetobacter baumannii ATCC 17978  A1S_2584  ABO13001.2  367 aa MFS family drug transporter 0.021 ○○○○○ 0.75 0.754273281466817
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5144  AIK83666.1  265 aa protein mtfA 0.00051 ○○○○○ 0.75 0.754387407839288
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0278  NP_229934.2  Q9KV78  519 aa DNA-binding transcriptional activator CadC 5.4e-6 ○○○○○ 0.75 0.754491212170425
Escherichia coli M12  CO715_22215  ATI08207.1  293 aa glucose-1-phosphate thymidylyltransferase 0.0038 ○○○○○ 0.75 0.754554498752599
Escherichia coli M12  CO715_08395  ATI05729.1  476 aa DUF2867 domain-containing protein 9.2e-5 ○○○○○ 0.75 0.754763144766847
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0195  NP_229852.1  Q9KVF1  302 aa RarD protein 0.0014 ○○○○○ 0.75 0.754852627159328
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0312  NP_232708.1  Q7DCR7  80 aa hypothetical protein 0.0092 ○○○○○ 0.76 0.755401361704635
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2022  AIK80628.1  55 aa putative lipoprotein 0.00082 ○○○○○ 0.76 0.75542966351167
Escherichia coli M12  CO715_01835  ATI04582.1  229 aa hypothetical protein 0.0054 ○○○○○ 0.76 0.755597728823843
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2401  AIK80998.1  47 aa hypothetical protein 1.1e-6 ○○○○○ 0.76 0.756492058288889
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1573  NP_231213.1  Q9KRR3  fumC  461 aa fumarate hydratase 0.00012 ○○○○○ 0.76 0.756618018487674
Escherichia coli M12  CO715_09380  ATI05904.1  135 aa hypothetical protein 0.026 ○○○○○ 0.76 0.756640958895087
Escherichia coli M12  CO715_02560  ATI04713.1  383 aa hypothetical protein 5.3e-12 ○○○○○ 0.76 0.756849604909336
Escherichia coli M12  CO715_22055  ATI08179.1  464 aa colanic acid biosynthesis protein WcaM 6.0e-5 ○○○○○ 0.76 0.757266896937834
Escherichia coli M12  CO715_00550  ATI04356.1  102 aa hypothetical protein 0.00052 ○○○○○ 0.76 0.757266896937834
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1510  AIK80130.1  701 aa 23S rRNA m2G2445 methyltransferase 1.3e-14 ○○○○○ 0.76 0.757569383276314
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2803  WP_001519447.1  E8XIF7  413 aa DUF21 domain-containing protein 0.03 ○○○○○ 0.76 0.757631589077017
Escherichia coli M12  CO715_12730  ATI06495.1  255 aa galactosamine-6-phosphate isomerase 0.013 ○○○○○ 0.76 0.757684188966332
Porphyromonas gingivalis ATCC 33277  PGN_1445  WP_012458275.1  B2RKR9  627 aa amidophosphoribosyltransferase <1e-323 ○○○○○ 0.76 0.75777243634455
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0862  NP_230509.1  Q9KTN9  122 aa hypothetical protein 0.027 ○○○○○ 0.76 0.75829143056131
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1512  AIK80131.1  369 aa putative 2Fe-2S cluster-containing protein 0.0097 ○○○○○ 0.76 0.758613920382881
Acinetobacter baumannii ATCC 17978  A1S_2101  ABO12528.2  396 aa putative transcriptional regulator 0.024 ○○○○○ 0.76 0.758931277891865
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0754  NP_233140.1  Q9KLJ0  276 aa lipase-like protein 0.0034 ○○○○○ 0.76 0.759080342214185
Porphyromonas gingivalis ATCC 33277  PGN_0400  WP_012457482.1  B2RHS4  926 aa TonB-dependent receptor 0.0051 ○○○○○ 0.76 0.759119803805991
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0678  NP_230327.1  P52695  hlyU  108 aa transcriptional activator HlyU 1.1e-5 ○○○○○ 0.76 0.759395186674701
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1920  NP_231554.1  Q9KQS8  lon  786 aa ATP-dependent protease LA 0.0065 ○○○○○ 0.76 0.760083069782754
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4335  AIK82880.1  261 aa precorrin-6x reductase 1.7e-10 ○○○○○ 0.76 0.760381657099052
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1527  AIK80147.1  358 aa outer membrane protein C 6.2e-12 ○○○○○ 0.76 0.760543117564765
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4536  AIK83074.1  222 aa gram-negative pili assembly chaperone, C-terminal domain protein 1.1e-5 ○○○○○ 0.76 0.760691840508394
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2115  AIK80720.1  87 aa ribosomal protein L31 1.0e-15 ○○○○○ 0.76 0.760921044994181
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0645  NP_233034.1  Q9KLU6  126 aa hypothetical protein 0.0076 ○○○○○ 0.76 0.761206049870004
Acinetobacter baumannii ATCC 17978  A1S_1804  ABO12231.2  310 aa putative transcriptional regulator LysR family 0.028 ○○○○○ 0.76 0.761255024558751
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2196  NP_231827.1  Q9KQ11  249 aa flagellar basal body rod protein FlgF 0.023 ○○○○○ 0.76 0.761416825680812
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0032  NP_232433.1  Q9KND3  186 aa hypothetical protein 0.023 ○○○○○ 0.76 0.761472472218204
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4217  AIK82762.1  136 aa arsenate reductase 9.5e-9 ○○○○○ 0.76 0.761715282452323
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1976  AIK80582.1  371 aa &gamma-glutamyl:cysteine ligase YbdK <1e-323 ○○○○○ 0.76 0.762372687046247
Escherichia coli M12  CO715_23900  ATI08484.1  190 aa type 1 fimbrial protein 0.00037 ○○○○○ 0.76 0.762483047294055
Porphyromonas gingivalis ATCC 33277  PGN_1816  WP_012458554.1  B2RLU0  220 aa hypothetical protein <1e-323 ○○○○○ 0.76 0.762546565011831
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4678  AIK83212.1  392 aa anaerobic sulfatase maturase <1e-323 ○○○○○ 0.76 0.763495436388109
Escherichia coli M12  CO715_15330  ATI06964.1  464 aa porin 4.0e-8 ○○○○○ 0.76 0.764152215408046
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3894  AIK82443.1  82 aa hypothetical protein 1.2e-11 ○○○○○ 0.76 0.764230416057356
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2077  NP_231709.1  Q9KQC3  758 aa ferrous iron transport protein B 0.038 ○○○○○ 0.76 0.764800472162277
Escherichia coli M12  CO715_21480  ATI08072.1  659 aa catecholate siderophore receptor CirA 0.026 ○○○○○ 0.77 0.765195445479291
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2216  NP_231847.1  Q9KPZ6  150 aa hypothetical protein 0.0053 ○○○○○ 0.77 0.765970969534675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0614  NP_230263.1  Q9KUA9  gspK  325 aa hypothetical protein 0.0069 ○○○○○ 0.77 0.766073955630485
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1228  NP_230873.1  Q9KSM8  purT  393 aa phosphoribosylglycinamide formyltransferase 2 0.0026 ○○○○○ 0.77 0.766148099088572
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2489  NP_232118.1  Q9KP84  211 aa TetR family transcriptional regulator 0.0079 ○○○○○ 0.77 0.766642004946037
Escherichia coli M12  CO715_10720  ATI06129.1  403 aa Bcr/CflA family drug resistance efflux transporter 4.8e-6 ○○○○○ 0.77 0.766655967579033
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1734  AIK80354.1  460 aa amino acid permease family protein <1e-323 ○○○○○ 0.77 0.767458445510997
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2294  AIK80898.1  339 aa acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta <1e-323 ○○○○○ 0.77 0.767693361791227
Escherichia coli M12  CO715_08480  ATI05745.1  162 aa hypothetical protein 0.00018 ○○○○○ 0.77 0.767699197650277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2863  AIK81452.1  467 aa amino acid permease family protein <1e-323 ○○○○○ 0.77 0.768036691380564
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2879  AIK81469.1  233 aa esterase <1e-323 ○○○○○ 0.77 0.768856090267561
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0979  NP_230626.1  Q9KTC3  275 aa short chain dehydrogenase 0.00066 ○○○○○ 0.77 0.769259239926923
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0601  NP_230251.1  Q9KUC1  820 aa ATP-dependent RNA helicase HrpB 0.0012 ○○○○○ 0.77 0.77001997455519
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1158  NP_230803.1  Q9KSU8  421 aa hypothetical protein 0.021 ○○○○○ 0.77 0.770220185783469
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1191  NP_230836.1  Q9KSR5  132 aa hypothetical protein 0.011 ○○○○○ 0.77 0.770903130602012
Acinetobacter baumannii ATCC 17978  A1S_2643  ABO13060.2  260 aa oxidoreductase short chain dehydrogenase/reductase family 0.024 ○○○○○ 0.77 0.771929801885741
Acinetobacter baumannii ATCC 17978  A1S_1210  ABO11640.2  452 aa major facilitator superfamily MFS_1 0.018 ○○○○○ 0.77 0.772150530902471
Escherichia coli M12  CO715_21435  ATI08063.1  313 aa pyrimidine-specific ribonucleoside hydrolase RihB 2.2e-10 ○○○○○ 0.77 0.77270670199225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4500  AIK83037.1  241 aa cupin domain protein <1e-323 ○○○○○ 0.77 0.772888375048763
Escherichia coli M12  CO715_02755  ATI04752.1  671 aa tRNA(Met) cytidine acetyltransferase 1.0e-5 ○○○○○ 0.77 0.772915348006498
Escherichia coli M12  CO715_22900  ATI08323.1  304 aa restriction endonuclease 1.3e-5 ○○○○○ 0.77 0.773123994020747
Escherichia coli M12  CO715_15030  ATI06911.1  475 aa iron-sulfur cluster-binding protein 2.1e-5 ○○○○○ 0.77 0.773332640034996
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1405  AIK80028.1  386 aa acyltransferase family protein <1e-323 ○○○○○ 0.77 0.774144864002641
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1109  AIK79732.1  510 aa HD domain protein 0.0052 ○○○○○ 0.77 0.774203001154247
Acinetobacter baumannii ATCC 17978  A1S_1457  ABO11885.2  173 aa putative chromate transport protein 0.028 ○○○○○ 0.77 0.774675392697649
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0516  NP_230167.1  Q9KUK2  413 aa phage integrase 0.04 ○○○○○ 0.77 0.774891953039378
Escherichia coli M12  CO715_23365  ATI08395.1  290 aa 50S ribosome-binding GTPase 4.1e-5 ○○○○○ 0.78 0.775001808148987
Escherichia coli M12  CO715_13610  ATI06650.1  254 aa gluconate 5-dehydrogenase 4.6e-13 ○○○○○ 0.78 0.775836392205982
Escherichia coli M12  CO715_23210  ATI08377.1  449 aa gluconate permease 0.00045 ○○○○○ 0.78 0.77625368423448
Retrieved entries 33,501–33,600 out of 36,363 total in 655.9 ms (Link to these results)