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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4486  WP_000919710.1  E8X9U1  proP  500 aa proline/glycine betaine transporter ProP 0.0082 ○○○○○ 0.91 0.912560116531622
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2172  NP_231803.1  Q9KQ32  160 aa hypothetical protein 0.0016 ○○○○○ 0.91 0.913219357907478
Escherichia coli M12  CO715_11310  ATI06239.1  326 aa aldo/keto reductase 2.2e-12 ○○○○○ 0.91 0.913542761610231
Acinetobacter baumannii ATCC 17978  A1S_0631  ABO11080.2  377 aa hypothetical protein 0.018 ○○○○○ 0.91 0.913594142951272
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1604  AIK80224.1  370 aa potF 1.7e-11 ○○○○○ 0.91 0.913814905397742
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1424  AIK80045.1  60 aa hypothetical protein 1.7e-6 ○○○○○ 0.91 0.914403717589054
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1482  AIK80103.1  112 aa anti-anti-sigma factor family protein 1.2e-8 ○○○○○ 0.91 0.91444128206252
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2138  NP_231769.1  Q9KQ65  fliS  136 aa flagellar protein FliS 0.019 ○○○○○ 0.91 0.914680926224088
Acinetobacter baumannii ATCC 17978  A1S_0338  ABO10798.2  A3M1K4  rbfA  133 aa ribosome-binding factor A 0.0019 ○○○○○ 0.92 0.915003277299053
Escherichia coli M12  CO715_10230  ATI08782.1  51 aa DUF1391 domain-containing protein 3.0e-11 ○○○○○ 0.92 0.915211929724222
Escherichia coli M12  CO715_24470  ATI08586.1  165 aa hypothetical protein 0.0043 ○○○○○ 0.92 0.915211929724222
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0106  WP_000951812.1  E8XH11  araB  569 aa ribulokinase 0.023 ○○○○○ 0.92 0.915307823710779
Acinetobacter baumannii ATCC 17978  A1S_0844  ABO11278.2  A3M2Y4  smpB  158 aa ssrA-binding protein (Small protein B) 0.0017 ○○○○○ 0.92 0.915326118622999
Porphyromonas gingivalis ATCC 33277  PGN_0205  WP_012457326.1  B2RH79  299 aa AraC family transcriptional regulator 0.0026 ○○○○○ 0.92 0.915609871495575
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2140  AIK80745.1  592 aa ABC transporter family protein <1e-323 ○○○○○ 0.92 0.915819390321343
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1209  WP_001043449.1  E8XEY0  ycfj  179 aa glycine zipper 2TM domain-containing protein 0.05 ○○○○○ 0.92 0.915909557314842
Escherichia coli M12  CO715_22110  ATI08186.1  548 aa acetolactate synthase 2 catalytic subunit 1.9e-11 ○○○○○ 0.92 0.916046513781217
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5089  AIK83615.1  203 aa type IV secretion system family protein 1.1e-16 ○○○○○ 0.92 0.916183271628527
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4853  AIK83380.1  556 aa 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 7.8e-11 ○○○○○ 0.92 0.916322589483699
Escherichia coli M12  CO715_18205  ATI07480.1  425 aa L-sorbose 1-phosphate reductase 1.5e-22 ○○○○○ 0.92 0.916463805809715
Acinetobacter baumannii ATCC 17978  A1S_1563  ABO11990.2  126 aa general secretion pathway protein I precursor 0.036 ○○○○○ 0.92 0.917871822448243
Escherichia coli M12  CO715_15565  ATI07004.1  726 aa catalase-peroxidase 2.9e-22 ○○○○○ 0.92 0.917924327909457
Escherichia coli M12  CO715_17990  ATI07443.1  479 aa 6-phospho-beta-glucosidase 1.7e-28 ○○○○○ 0.92 0.918967557980701
Acinetobacter baumannii ATCC 17978  A1S_0635  ABO11084.2  445 aa hypothetical bacteriophage protein 0.0022 ○○○○○ 0.92 0.919458281417501
Escherichia coli M12  CO715_04545  ATI05072.1  426 aa MFS transporter 1.6e-13 ○○○○○ 0.92 0.920010788051946
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2135  WP_001029484.1  E8XC04  pduO  336 aa two-domain cob(I)yrinic acid a,c-diamide adenosyltransferase PduO 0.042 ○○○○○ 0.92 0.920101950794114
Escherichia coli M12  CO715_23585  ATI08430.1  258 aa hydroxypyruvate isomerase 5.1e-9 ○○○○○ 0.92 0.920636726094692
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5051  AIK83577.1  474 aa exonuclease I, 3' -- 5' specific deoxyribophosphodiesterase <1e-323 ○○○○○ 0.92 0.920726438136712
Acinetobacter baumannii ATCC 17978  A1S_1738  ABO12165.2  321 aa putative transcriptional regulator 0.021 ○○○○○ 0.92 0.920842133877898
Escherichia coli M12  CO715_13390  ATI06615.1  341 aa amino acid ABC transporter substrate-binding protein 0.021 ○○○○○ 0.92 0.920845372108941
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2229  NP_231860.1  Q9KPY3  281 aa hypothetical protein 0.0095 ○○○○○ 0.92 0.920938988115232
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1828  AIK80441.1  467 aa outer membrane porin, OprD family protein <1e-323 ○○○○○ 0.92 0.921035346145188
Escherichia coli M12  CO715_03885  ATI04955.1  773 aa RNA-binding transcriptional accessory protein 3.3e-14 ○○○○○ 0.92 0.921262664137439
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1810  AIK80423.1  247 aa conserved metal-binding protein 0.0041 ○○○○○ 0.92 0.921590523852864
Acinetobacter baumannii ATCC 17978  A1S_1942  ABO12369.2  139 aa hypothetical protein 0.0024 ○○○○○ 0.92 0.921791184690053
Porphyromonas gingivalis ATCC 33277  PGN_2077  WP_004585614.1  B2RMK0  60 aa (2Fe-2S)-binding protein <1e-323 ○○○○○ 0.92 0.921970471357599
Escherichia coli M12  CO715_14485  ATI06810.1  911 aa ABC transporter ATP-binding protein/permease 1.6e-14 ○○○○○ 0.92 0.922097248194434
Escherichia coli M12  CO715_00495  ATI04345.1  676 aa alpha-amylase 3.5e-12 ○○○○○ 0.92 0.922097248194434
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1095  NP_230740.1  Q9KT10  336 aa oligopeptide ABC transporter ATP-binding protein 0.0014 ○○○○○ 0.92 0.922400350352261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2430  WP_001012861.1  E8XEY6  yfbS  608 aa SLC13 family permease 0.05 ○○○○○ 0.92 0.923192207831154
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4906  AIK83432.1  398 aa drug resistance transporter, Bcr/CflA subfamily protein <1e-323 ○○○○○ 0.92 0.923909283270998
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4097  WP_000193413.1  E8XIM9  wzzE  348 aa ECA polysaccharide chain length modulation protein 0.048 ○○○○○ 0.92 0.924064941149276
Porphyromonas gingivalis ATCC 33277  PGN_0149  WP_004584679.1  B2RH23  prs  313 aa ribose-phosphate pyrophosphokinase 4.9e-9 ○○○○○ 0.92 0.924692361721378
Porphyromonas gingivalis ATCC 33277  PGN_0158  WP_012457288.1  B2RH32  thiG  259 aa thiazole synthase 0.023 ○○○○○ 0.92 0.924692361721378
Escherichia coli M12  CO715_14240  ATI06763.1  274 aa AraC family transcriptional regulator 6.3e-18 ○○○○○ 0.92 0.924809646379669
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2332  AIK80936.1  256 aa hydrolase <1e-323 ○○○○○ 0.93 0.925249600928005
Escherichia coli M12  CO715_23195  ATI08374.1  262 aa IclR family transcriptional regulator 1.7e-8 ○○○○○ 0.93 0.925644230436665
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1952  NP_231586.1  Q9KQP6  846 aa chitinase 0.034 ○○○○○ 0.93 0.927114596612406
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2046  AIK80652.1  390 aa oxidoreductase, NAD-binding Rossmann fold family protein <1e-323 ○○○○○ 0.93 0.927720302912738
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2471  NP_232100.1  Q9KPA2  sdhE  86 aa hypothetical protein 6.0e-5 ○○○○○ 0.93 0.927777282048865
Escherichia coli M12  CO715_03545  ATI04893.1  296 aa ISNCY family transposase 2.8e-10 ○○○○○ 0.93 0.927939336593402
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0404  NP_230058.1  Q9KUV8  389 aa MSHA biogenesis protein MshN 0.00064 ○○○○○ 0.93 0.929218084560613
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0836  WP_001129814.1  E8XBS4  ybhn  320 aa UPF0104 family protein 0.019 ○○○○○ 0.93 0.93067280242432
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3866  WP_000586988.1  E8XG08  lldD  396 aa quinone-dependent L-lactate dehydrogenase 0.029 ○○○○○ 0.93 0.930692531190624
Escherichia coli M12  CO715_17385  ATI07335.1  215 aa L-fuculose-phosphate aldolase 1.6e-67 ○○○○○ 0.93 0.931069026807135
Escherichia coli M12  CO715_18370  ATI07510.1  348 aa L-asparaginase 2 7.7e-8 ○○○○○ 0.93 0.931277672821384
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0237  NP_232635.1  Q9KMT3  189 aa hypothetical protein 0.034 ○○○○○ 0.93 0.931884763554359
Escherichia coli M12  CO715_22700  ATI08287.1  338 aa lipoate--protein ligase A 0.0001 ○○○○○ 0.93 0.932320902892628
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2668  NP_232296.1  Q9KNR3  146 aa hypothetical protein 0.00012 ○○○○○ 0.93 0.932349962620063
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2854  AIK81443.1  68 aa hypothetical protein 8.0e-6 ○○○○○ 0.93 0.93252367059449
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0117  WP_001140629.1  E8XH22  leuC  466 aa 3-isopropylmalate dehydratase large subunit 0.04 ○○○○○ 0.93 0.932617000418538
Escherichia coli M12  CO715_15860  ATI07054.1  266 aa pyridoxal phosphate phosphatase YigL 2.7e-7 ○○○○○ 0.93 0.932738194921126
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0781  WP_000115347.1  E8XAY6  nadA  347 aa quinolinate synthase NadA 0.023 ○○○○○ 0.93 0.933405639545715
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0736  NP_233123.1  Q9KLK7  luxQ  857 aa sensor histidine kinase LuxQ 0.008 ○○○○○ 0.93 0.933497063045105
Escherichia coli M12  CO715_00720  ATI04385.1  96 aa acetolactate synthase isozyme 1 small subunit 0.022 ○○○○○ 0.93 0.933572778978122
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4459  AIK83002.1  136 aa formate hydrogenlyase maturation HycH family protein 1.5e-7 ○○○○○ 0.93 0.934647487818987
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1116  WP_000083126.1  E8XE80  ycdC  212 aa HTH-type transcriptional regulator RutR 0.041 ○○○○○ 0.93 0.934930389115899
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2239  NP_231870.1  Q9KPX3  114 aa nitrogen regulatory protein P-II 0.0045 ○○○○○ 0.94 0.935671401071231
Escherichia coli M12  CO715_23480  ATI08410.1  391 aa HlyD family type I secretion periplasmic adaptor subunit 7.9e-11 ○○○○○ 0.94 0.937328407234601
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1717  WP_001623919.1  E8XKR7  yciR  660 aa cyclic di-GMP phosphodiesterase 0.037 ○○○○○ 0.94 0.937376036367449
Escherichia coli M12  CO715_05355  ATI05205.1  214 aa protein phosphatase CheZ 0.00045 ○○○○○ 0.94 0.938371637305845
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5011  AIK83537.1  527 aa transporter associated domain protein 5.5e-5 ○○○○○ 0.94 0.93842478475332
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0695  NP_233082.1  Q9KLP8  223 aa hypothetical protein 0.0025 ○○○○○ 0.94 0.939387232900277
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2616  NP_232244.1  Q9KNW4  astD  485 aa succinylglutamic semialdehyde dehydrogenase 0.0017 ○○○○○ 0.94 0.93954307536426
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4553  WP_000968675.1  E8XAN2  yjeF  515 aa bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.0064 ○○○○○ 0.94 0.939952064850468
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5160  AIK83681.1  61 aa endodeoxyribonuclease RusA family protein 3.2e-8 ○○○○○ 0.94 0.940089923783106
Escherichia coli M12  CO715_03425  ATI04870.1  274 aa penicillin-insensitive murein endopeptidase 5.5e-15 ○○○○○ 0.94 0.940249451434085
Escherichia coli M12  CO715_13475  ATI08809.1  396 aa integrase 7.7e-7 ○○○○○ 0.94 0.940666743462583
Acinetobacter baumannii ATCC 17978  A1S_1731  ABO12158.1  213 aa acetoacetyl-CoA transferase beta subunit 0.022 ○○○○○ 0.94 0.940830268975489
Escherichia coli M12  CO715_12435  ATI06442.1  378 aa 23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG 8.9e-5 ○○○○○ 0.94 0.941084035491081
Escherichia coli M12  CO715_12450  ATI08799.1  328 aa gfo/Idh/MocA family oxidoreductase 0.0032 ○○○○○ 0.94 0.941709973533827
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3852  WP_000183985.1  E8XFZ4  aldB  512 aa aldehyde dehydrogenase 0.04 ○○○○○ 0.94 0.942179698069087
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1703  AIK80323.1  249 aa short chain dehydrogenase family protein <1e-323 ○○○○○ 0.94 0.942212940848656
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4493  WP_000106992.1  E8X9U8  melR  310 aa transcriptional regulator MelR 0.048 ○○○○○ 0.94 0.942721251925173
Escherichia coli M12  CO715_22205  ATI08205.1  420 aa UDP-N-acetyl-D-mannosamine dehydrogenase 4.2e-9 ○○○○○ 0.94 0.94296184961932
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0403  NP_230057.1  H9L4Q2  281 aa MSHA biogenesis protein MshM 4.6e-5 ○○○○○ 0.94 0.943053136493044
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5053  AIK83579.1  157 aa gyrI-like small molecule binding domain protein 4.1e-15 ○○○○○ 0.94 0.943268068531666
Escherichia coli M12  CO715_23935  ATI08490.1  276 aa rhomboid family intramembrane serine protease GlpG 0.022 ○○○○○ 0.94 0.943379141647818
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4592  WP_000381075.1  E8XAS0  yifZ  308 aa DMT family transporter 0.0077 ○○○○○ 0.94 0.943648471743971
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1010  NP_233394.1  Q9KKU0  ribN  298 aa hypothetical protein 0.0028 ○○○○○ 0.94 0.944688388224424
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4933  AIK83459.1  385 aa hypothetical protein 1.9e-15 ○○○○○ 0.94 0.944883731935389
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1181  AIK79804.1  324 aa cysB 0.015 ○○○○○ 0.95 0.945195886302987
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2379  WP_000948739.1  E8XEC5  glpT  452 aa glycerol-3-phosphate transporter 0.043 ○○○○○ 0.95 0.945217824217033
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1584  AIK80204.1  333 aa ltaA 1.8e-9 ○○○○○ 0.95 0.945647399131733
Acinetobacter baumannii ATCC 17978  A1S_1696  ABO12123.2  250 aa hypothetical protein 0.0054 ○○○○○ 0.95 0.946034744138207
Escherichia coli M12  CO715_16160  ATI07110.1  457 aa aromatic amino acid transporter AroP 1.2e-6 ○○○○○ 0.95 0.946508831861551
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2319  AIK80923.1  351 aa impB/mucB/samB family protein 3.4e-7 ○○○○○ 0.95 0.94669405044697
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0473  NP_230127.1  Q9KUP2  tkt1  694 aa transketolase 0.0018 ○○○○○ 0.95 0.947539812844347
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4477  WP_000551709.1  E8X9T2  nrfE  740 aa heme lyase NrfEFG subunit NrfEF 0.045 ○○○○○ 0.95 0.947677522047713
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2471  WP_000127736.1  E8XF27  yfcj  392 aa MFS transporter 0.016 ○○○○○ 0.95 0.947804170444957
Retrieved entries 34,001–34,100 out of 36,363 total in 702.8 ms (Link to these results)