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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0577  WP_002856730.1  A0A0H3PJ60  230 aa DUF969 domain-containing protein 0.039 ○○○○○ 1.83 1.82937814976
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0634  WP_002856742.1  A0A0H3PBN0  396 aa amidohydrolase 0.039 ○○○○○ 1.83 1.83020941592
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5136  AIK83660.1  234 aa regulatory protein TetR family <1e-323 ○○○○○ 1.83 1.83021259038781
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0439  WP_002869237.1  A0A0H3PAP4  573 aa GMC family oxidoreductase 0.039 ○○○○○ 1.83 1.83396033573
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0439  WP_002869238.1  A0A0H3PAP4  32 aa hypothetical protein 0.039 ○○○○○ 1.83 1.83396033573
Mycobacterium avium subsp. paratuberculosis K10  MAP_0008c  AAS02325.1  Q744Q6  192 aa hypothetical protein 0.024 ○○○○○ 1.84 1.83549737111389
Mycobacterium avium subsp. paratuberculosis K10  MAP_2569c  AAS04886.1  Q73WU1  329 aa hypothetical protein 0.024 ○○○○○ 1.84 1.83656525407921
Mycobacterium avium subsp. paratuberculosis K10  MAP_1616  AAS03933.1  Q73ZI7  104 aa hypothetical protein 0.024 ○○○○○ 1.84 1.83907638642962
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0931  WP_002855874.1  A0A0H3PA34  cheB  184 aa chemotaxis protein CheB 0.038 ○○○○○ 1.84 1.83918527621
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5032  AIK83558.1  246 aa ABC transporter family protein 0.012 ○○○○○ 1.84 1.84036338385582
Acinetobacter baumannii ATCC 17978  A1S_1688  ABO12115.2  A3M5C1  101 aa hypothetical protein 2.9e-16 ○○○○○ 1.84 1.84059741440647
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1184  AIK79807.1  348 aa peptidase S49 family protein <1e-323 ○○○○○ 1.84 1.84141328931311
Streptococcus pyogenes M1 5448  SP5448_03595  WP_002988369.1  89 aa hypothetical protein 0.017 ○○○○○ 1.84 1.8427055084712
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0313  NP_232709.1  Q9KMM0  128 aa MutT/nudix family protein 0.00026 ○○○○○ 1.84 1.84401322610525
Mycobacterium avium subsp. paratuberculosis K10  MAP_3461  AAS06011.1  Q73UA7  203 aa hypothetical protein 0.024 ○○○○○ 1.85 1.84641872504751
Escherichia coli O157:H7 str. EDL933  Z2015  AAG56095.1  205 aa thymidine kinase 0.032 ○○○○○ 1.85 1.84840523422524
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1042  WP_002856173.1  A0A0H3PHA3  asd  343 aa aspartate-semialdehyde dehydrogenase 0.038 ○○○○○ 1.85 1.84886311479
Acinetobacter baumannii ATCC 17978  A1S_2164  ABO12591.2  792 aa phosphoenolpyruvate synthase 3.1e-6 ○○○○○ 1.85 1.84895609543056
Mycobacterium avium subsp. paratuberculosis K10  MAP_1572c  AAS03889.1  Q73ZM9  251 aa hypothetical protein 0.024 ○○○○○ 1.85 1.84919950043428
Mycobacterium avium subsp. paratuberculosis K10  MAP_4007c  AAS06557.1  Q73SR6  146 aa hypothetical protein 0.024 ○○○○○ 1.85 1.84960085395743
Mycobacterium avium subsp. paratuberculosis K10  MAP_2936c  AAS05253.1  Q73VS5  620 aa hypothetical protein 0.024 ○○○○○ 1.85 1.85247652446682
Mycobacterium avium subsp. paratuberculosis K10  MAP_2216c  AAS04533.1  Q73XU2  lppR  252 aa LppR 0.024 ○○○○○ 1.85 1.85256767573137
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0106  NP_229765.1  Q9KVN5  143 aa hypothetical protein 0.00017 ○○○○○ 1.85 1.85260906958134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2035  AIK80641.1  456 aa negative regulator of sacY activity <1e-323 ○○○○○ 1.86 1.85605553943063
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4901  AIK83427.1  435 aa beta-lactamase family protein <1e-323 ○○○○○ 1.86 1.85610694237962
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0606  WP_002856930.1  A0A0H3PAS9  tatC  245 aa twin-arginine translocase subunit TatC 0.037 ○○○○○ 1.86 1.85623481279
Escherichia coli M12  CO715_13840  ATI06693.1  68 aa hypothetical protein 0.0012 ○○○○○ 1.86 1.85683139202933
Mycobacterium avium subsp. paratuberculosis K10  MAP_3813  AAS06363.1  Q73TA5  101 aa hypothetical protein 0.023 ○○○○○ 1.86 1.85836546395823
Escherichia coli M12  CO715_22940  ATI08330.1  426 aa DUF445 domain-containing protein 0.0024 ○○○○○ 1.86 1.86016972825731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1135  AIK79758.1  84 aa hypothetical protein 1.9e-15 ○○○○○ 1.86 1.86069990560424
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1715  AIK80335.1  321 aa hypothetical protein 1.7e-11 ○○○○○ 1.86 1.86112421443927
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0051  NP_232452.1  Q9KNB4  507 aa hypothetical protein 0.0064 ○○○○○ 1.86 1.86115648231704
Mycobacterium avium subsp. paratuberculosis K10  MAP_3073  AAS05621.1  Q73VE1  103 aa hypothetical protein 0.023 ○○○○○ 1.86 1.86178932163318
Mycobacterium avium subsp. paratuberculosis K10  MAP_1967c  AAS04284.1  Q73YI9  522 aa hypothetical protein 0.023 ○○○○○ 1.86 1.8631764998248
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0512  NP_232903.1  Q9KM76  nrdG  155 aa anaerobic ribonucleotide reductase-activating protein 0.026 ○○○○○ 1.86 1.86351982579956
Mycobacterium avium subsp. paratuberculosis K10  MAP_1608c  AAS03925.1  Q73ZJ5  168 aa hypothetical protein 0.023 ○○○○○ 1.86 1.86419337878993
Mycobacterium avium subsp. paratuberculosis K10  MAP_1160c  AAS03477.1  Q741D1  269 aa hypothetical protein 0.023 ○○○○○ 1.86 1.86445662736094
Streptococcus pyogenes M1 5448  SP5448_05045  WP_002984598.1  356 aa tyrosine recombinase XerS 0.035 ○○○○○ 1.86 1.86481624792669
Mycobacterium avium subsp. paratuberculosis K10  MAP_1823c  AAS04140.1  Q73YY0  pepE  375 aa PepE 0.023 ○○○○○ 1.87 1.86899645106024
Mycobacterium avium subsp. paratuberculosis K10  MAP_0966c  AAS03283.1  Q741X1  422 aa hypothetical protein 0.023 ○○○○○ 1.87 1.8690501598779
Porphyromonas gingivalis ATCC 33277  PGN_1934  WP_012458620.1  B2RM58  78 aa hypothetical protein 0.0027 ○○○○○ 1.87 1.86990701071267
Mycobacterium avium subsp. paratuberculosis K10  MAP_0853  AAS03170.1  Q742I2  219 aa hypothetical protein 0.023 ○○○○○ 1.87 1.87010616895625
Mycobacterium avium subsp. paratuberculosis K10  MAP_2762c  AAS05079.1  Q73W98  146 aa hypothetical protein 0.023 ○○○○○ 1.87 1.87022240930878
Escherichia coli M12  CO715_20290  ATI07856.1  102 aa hypothetical protein 3.3e-17 ○○○○○ 1.87 1.8712279670125
Mycobacterium avium subsp. paratuberculosis K10  MAP_3633  AAS06183.1  Q73TT5  414 aa hypothetical protein 0.023 ○○○○○ 1.87 1.87179714151002
Escherichia coli M12  CO715_18810  ATI07586.1  113 aa ribosomal subunit interface protein 2.0e-214 ○○○○○ 1.87 1.87435765722624
Streptococcus pyogenes M1 5448  SP5448_05450  WP_011285520.1  258 aa ABC transporter permease 0.035 ○○○○○ 1.88 1.87731362240153
Mycobacterium avium subsp. paratuberculosis K10  MAP_2635c  AAS04952.1  Q73WM5  800 aa hypothetical protein 0.022 ○○○○○ 1.88 1.87782760219311
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1447  WP_002869185.1  A1W162  rimO  439 aa 30S ribosomal protein S12 methylthiotransferase RimO 0.035 ○○○○○ 1.88 1.87932060752
Escherichia coli M12  CO715_05470  ATI05226.1  261 aa zinc ABC transporter permease 0.0099 ○○○○○ 1.88 1.8801997456252
Mycobacterium avium subsp. paratuberculosis K10  MAP_1350c  AAS03667.1  Q740K0  494 aa hypothetical protein 0.022 ○○○○○ 1.88 1.88024483229495
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1318  WP_009882875.1  Q2M5Q6  520 aa HAD-IIIC family phosphatase 0.035 ○○○○○ 1.88 1.88077777735
Mycobacterium avium subsp. paratuberculosis K10  MAP_3398c  AAS05948.1  Q73UH0  512 aa hypothetical protein 0.022 ○○○○○ 1.89 1.88520715322541
Mycobacterium avium subsp. paratuberculosis K10  MAP_2356  AAS04673.1  Q73XF3  343 aa hypothetical protein 0.022 ○○○○○ 1.89 1.88522904382453
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1075  NP_230720.1  Q9KT30  180 aa hypothetical protein 0.016 ○○○○○ 1.89 1.8864118109359
Mycobacterium avium subsp. paratuberculosis K10  MAP_2541c  AAS04858.1  P61976  mdh  329 aa Mdh 0.022 ○○○○○ 1.89 1.88654531426114
Mycobacterium avium subsp. paratuberculosis K10  MAP_1525  AAS03842.1  Q73ZS6  294 aa hypothetical protein 0.022 ○○○○○ 1.89 1.88658666144112
Escherichia coli M12  CO715_03920  ATI04962.1  574 aa DUF4153 domain-containing protein <1e-323 ○○○○○ 1.89 1.88687641808117
Streptococcus pyogenes M1 5448  SP5448_07330  WP_002985634.1  283 aa Rgg/GadR/MutR family transcriptional regulator 0.047 ○○○○○ 1.89 1.88692698738218
Mycobacterium avium subsp. paratuberculosis K10  MAP_1242  AAS03559.1  Q740V0  pstA  4027 aa PstA 0.022 ○○○○○ 1.89 1.88943935791848
Mycobacterium avium subsp. paratuberculosis K10  MAP_2325  AAS04642.1  Q73XI4  eis  412 aa hypothetical protein 0.022 ○○○○○ 1.89 1.88947709656102
Porphyromonas gingivalis ATCC 33277  PGN_0464  WP_012457526.1  B2RHY8  995 aa tetratricopeptide repeat protein <1e-323 ○○○○○ 1.89 1.89090393499175
Mycobacterium avium subsp. paratuberculosis K10  MAP_3259  AAS05807.1  Q73UV7  pknJ  333 aa PknJ 0.022 ○○○○○ 1.89 1.8928096056252
Mycobacterium avium subsp. paratuberculosis K10  MAP_4026  AAS06576.1  Q73SP7  434 aa hypothetical protein 0.022 ○○○○○ 1.89 1.89346073555339
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0093  WP_024088096.1  A0A0H3PGT9  164 aa hypothetical protein 0.034 ○○○○○ 1.89 1.89471702649
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1111  AIK79734.1  304 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 1.9 1.89581563459594
Serratia marcescens Strain UMH9  BVG96_04240  ASL96857.1  864 aa fimbrial protein 0.0014 ○○○○○ 1.9 1.89625323037812
Mycobacterium avium subsp. paratuberculosis K10  MAP_3744  AAS06294.1  Q73TH4  344 aa hypothetical protein 0.022 ○○○○○ 1.9 1.89659016442921
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1056  AIK79679.1  1175 aa ferredoxin (flavodoxin) oxidoreductase <1e-323 ○○○○○ 1.9 1.8972984498802
Acinetobacter baumannii ATCC 17978  A1S_1219  ABO11649.2  135 aa Glutathione-dependent formaldehyde-activating GFA 0.0013 ○○○○○ 1.9 1.899165878767
Acinetobacter baumannii ATCC 17978  A1S_1734  ABO12161.2  275 aa hypothetical protein 7.4e-8 ○○○○○ 1.9 1.89984378717811
Mycobacterium avium subsp. paratuberculosis K10  MAP_1855  AAS04172.1  Q73YV0  409 aa hypothetical protein 0.021 ○○○○○ 1.9 1.90045579621216
Mycobacterium avium subsp. paratuberculosis K10  MAP_3173c  AAS05721.1  Q73V43  166 aa hypothetical protein 0.021 ○○○○○ 1.9 1.9016898412158
Mycobacterium avium subsp. paratuberculosis K10  MAP_2756c  AAS05073.1  Q73WA4  1636 aa hypothetical protein 0.021 ○○○○○ 1.9 1.90171710040395
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3917  AIK82466.1  178 aa general stress protein 18 <1e-323 ○○○○○ 1.9 1.903240665146
Streptococcus pyogenes M1 5448  SP5448_03475  WP_002994744.1  126 aa ImmA/IrrE family metallo-endopeptidase 0.022 ○○○○○ 1.91 1.90519238084541
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3925  AIK82473.1  287 aa 16S rRNA 2'-O-ribose C1402 methyltransferase <1e-323 ○○○○○ 1.91 1.90597282058792
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1224  AIK79847.1  274 aa chbR transcriptional regulator ChbR transcriptional dual regulator 4.0e-6 ○○○○○ 1.91 1.90736927183581
Mycobacterium avium subsp. paratuberculosis K10  MAP_3485  AAS06035.1  Q73U83  kasB  419 aa KasB_2 0.021 ○○○○○ 1.91 1.90749659099177
Mycobacterium avium subsp. paratuberculosis K10  MAP_0107  AAS02424.1  Q745A4  119 aa hypothetical protein 0.021 ○○○○○ 1.91 1.90770719514155
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5182  AIK83703.1  815 aa phage tail tape measure protein, lambda family <1e-323 ○○○○○ 1.91 1.91121450210313
Acinetobacter baumannii ATCC 17978  A1S_1974  ABO12401.2  A3M657  frr  184 aa ribosome releasing factor 0.0019 ○○○○○ 1.91 1.91175216919359
Mycobacterium avium subsp. paratuberculosis K10  MAP_3460c  AAS06010.1  Q73UA8  461 aa hypothetical protein 0.021 ○○○○○ 1.91 1.91223911704133
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2562  AIK81159.1  249 aa ubiquinol-cytochrome C chaperone family protein <1e-323 ○○○○○ 1.91 1.91238958013556
Escherichia coli M12  CO715_25075  ATI08668.1  113 aa adhesin 0.0031 ○○○○○ 1.91 1.91316581587653
Acinetobacter baumannii ATCC 17978  A1S_2126  ABO12553.1  246 aa aconitate hydratase 2 0.025 ○○○○○ 1.91 1.91401478555246
Serratia marcescens Strain UMH9  BVG96_11830  ASL98272.1  517 aa GGDEF domain-containing protein 0.024 ○○○○○ 1.91 1.91474283507808
Porphyromonas gingivalis ATCC 33277  PGN_1045  WP_012457982.1  B2RJL9  lacZII  1068 aa DUF4981 domain-containing protein <1e-323 ○○○○○ 1.92 1.9175593875417
Mycobacterium avium subsp. paratuberculosis K10  MAP_3671  AAS06221.1  Q73TP7  227 aa hypothetical protein 0.021 ○○○○○ 1.92 1.91841008589308
Escherichia coli M12  CO715_15600  ATI07011.1  106 aa fructose-like phosphotransferase enzyme IIB component 2 0.02 ○○○○○ 1.92 1.91879925826124
Mycobacterium avium subsp. paratuberculosis K10  MAP_0164  AAS02481.1  Q745F7  509 aa hypothetical protein 0.021 ○○○○○ 1.92 1.91990297640192
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1056  WP_002856595.1  A0A0H3PD54  accC-1  481 aa acetyl-CoA carboxylase subunit A 0.033 ○○○○○ 1.92 1.92116364649
Escherichia coli M12  CO715_24150  ATI08531.1  136 aa large conductance mechanosensitive channel protein MscL 0.0097 ○○○○○ 1.92 1.92130301043223
Mycobacterium avium subsp. paratuberculosis K10  MAP_2659  AAS04976.1  Q73WK1  280 aa hypothetical protein 0.021 ○○○○○ 1.92 1.92309577486696
Mycobacterium avium subsp. paratuberculosis K10  MAP_3824  AAS06374.1  Q73T94  448 aa hypothetical protein 0.02 ○○○○○ 1.93 1.92630885953329
Mycobacterium avium subsp. paratuberculosis K10  MAP_1025  AAS03342.1  Q741R2  pra  241 aa Pra 0.02 ○○○○○ 1.93 1.92661674314945
Streptococcus pyogenes M1 5448  SP5448_03015  WP_011285654.1  564 aa hyaluronidase 0.038 ○○○○○ 1.93 1.9273031203009
Porphyromonas gingivalis ATCC 33277  PGN_1629  WP_021676670.1  B2RLA3  302 aa DMT family transporter <1e-323 ○○○○○ 1.93 1.92777886652292
Mycobacterium avium subsp. paratuberculosis K10  MAP_1577  AAS03894.1  Q73ZM5  494 aa hypothetical protein 0.02 ○○○○○ 1.93 1.92788804210923
Mycobacterium avium subsp. paratuberculosis K10  MAP_1421  AAS03738.1  Q740D0  asnB  601 aa AsnB_1 0.02 ○○○○○ 1.93 1.92788927048041
Retrieved entries 35,601–35,700 out of 36,363 total in 1484.3 ms (Link to these results)