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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3004  WP_014344400.1  E8XKZ3  avrA  301 aa type III secretion system YopJ family effector AvrA 6.5e-7 ●●●●○ -3.15 -3.14633230601217
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3232  WP_001576357.1  E8XAD4  266 aa FadR family transcriptional regulator 1.5e-5 ●●●●○ -3.14 -3.14460024652412
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1549  AIK80169.1  362 aa phosphoserine transaminase 5.2e-5 ●●●●○ -3.14 -3.1442857838189
Haemophilus influenzae Rd KW20  HI_0600  NP_438757.1  P43705  recA  354 aa recombinase A 0.0024 ●●●●○ -3.14 -3.14384023917427
Streptococcus pyogenes M1 5448  SP5448_01345  WP_002986031.1  279 aa undecaprenyl-diphosphate phosphatase 0.00061 ●●●●○ -3.14 -3.14086289749673
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3715  WP_001066509.1  E8XEQ1  253 aa hypothetical protein 1.5e-25 ●●●●○ -3.14 -3.13768186464601
Acinetobacter baumannii ATCC 17978  A1S_0574  ABO11027.2  935 aa GacS-like sensor kinase protein 3.1e-23 ●●●●○ -3.14 -3.13631481701742
Mycobacterium avium subsp. paratuberculosis K10  MAP_1006  AAS03323.1  Q741T1  256 aa hypothetical protein 0.00096 ●●●●○ -3.14 -3.1360818649737
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4537  WP_000609649.1  E8XAL9  frdD  119 aa fumarate reductase subunit FrdD 1.7e-5 ●●●●○ -3.14 -3.1357337198599
Mycobacterium avium subsp. paratuberculosis K10  MAP_3702  AAS06252.1  Q73TL6  nirB  855 aa NirB 0.00096 ●●●●○ -3.14 -3.13545338651367
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1923  WP_000625584.1  E8X9F8  znuA  319 aa zinc ABC transporter substrate-binding protein ZnuA 3.8e-8 ●●●●○ -3.13 -3.13304523533169
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0835  WP_001052198.1  E8XBS3  186 aa membrane protein 6.8e-25 ●●●●○ -3.13 -3.13196448219247
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0690  WP_000493272.1  E8XA28  361 aa PhoH family protein 5.5e-8 ●●●●○ -3.13 -3.13100329140111
Vibrio parahaemolyticus RIMD 2210633  VP_0848  BAC59111.1  Q87RE9  401 aa 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 0.0026 ●●●●○ -3.13 -3.13091590947689
Vibrio parahaemolyticus RIMD 2210633  VP_2879  BAC61142.1  Q87KU6  aroQ  149 aa 3-dehydroquinate dehydratase 0.0026 ●●●●○ -3.13 -3.13091590947689
Acinetobacter baumannii ATCC 17978  A1S_0274  ABO10749.2  497 aa anthranilate synthase component I; TrpE 1.6e-43 ●●●●○ -3.13 -3.128456443965
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2501  CBW18602.1  A0A0H3NEE0  hscA  616 aa Chaperone protein hscA 3.0e-11 ●●●●○ -3.13 -3.12606236174155
Vibrio parahaemolyticus RIMD 2210633  VP_0794  BAC59057.1  Q87RK0  574 aa phosphoenolpyruvate-protein phosphotransferase 0.0026 ●●●●○ -3.13 -3.1255279975142
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1002  NP_230648.1  Q9KTA1  198 aa DedD protein 2.9e-14 ●●●●○ -3.12 -3.12280232560604
Streptococcus pyogenes M1 5448  SP5448_07835  WP_010921933.1  287 aa 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9.1e-5 ●●●●○ -3.12 -3.12163616753543
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4387  WP_000587738.1  E8X8V5  242 aa hypothetical protein 2.4e-20 ●●●●○ -3.12 -3.1214345847599
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3933  CBW20024.1  A0A0H3NNJ2  fre  233 aa flavin reductase 4.3e-10 ●●●●○ -3.12 -3.1201515905882
Streptococcus pyogenes M1 5448  SP5448_07840  WP_002985838.1  107 aa DNA replication initiation control protein YabA 0.0032 ●●●●○ -3.12 -3.1197134945393
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4397  WP_000703632.1  E8X8W5  309 aa glycosyltransferase 1.0e-14 ●●●●○ -3.12 -3.118933037433
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0185  CBW16287.1  A0A0H3N7Q0  pcnB  472 aa poly(A) polymerase 3.3e-10 ●●●●○ -3.12 -3.11852290240654
Haemophilus influenzae Rd KW20  HI_0313  NP_438479.1  P44632  ruvA  204 aa Holliday junction DNA helicase RuvA 0.0026 ●●●●○ -3.12 -3.11832471018123
Streptococcus pyogenes M1 5448  SP5448_05620  WP_010922266.1  598 aa excinuclease ABC subunit UvrC 0.0023 ●●●●○ -3.12 -3.11586814854704
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2295  CBW18397.1  A0A0H3NFB3  nuoC  600 aa NADH dehydrogenase I chain C; chain D 1.4e-8 ●●●●○ -3.11 -3.11281870189159
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2158  WP_000102719.1  E8XC27  hisC  359 aa histidinol-phosphate transaminase 9.0e-8 ●●●●○ -3.11 -3.11189503348585
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1329  CBW17425.1  A0A0H3NB62  ssaD  403 aa hypothetical pathogenicity island protein 4.7e-9 ●●●●○ -3.11 -3.10986329968145
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0945  WP_000537407.1  E8XCR5  trxB  322 aa thioredoxin-disulfide reductase 1.7e-24 ●●●●○ -3.11 -3.10965139654543
Serratia marcescens Strain UMH9  BVG96_22745  ASM00252.1  554 aa alpha,alpha-phosphotrehalase 0.0051 ●●●●○ -3.11 -3.10836945846216
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0338  WP_000893231.1  E8XJM5  proA  416 aa glutamate-5-semialdehyde dehydrogenase 1.5e-7 ●●●●○ -3.11 -3.10829135490986
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3885  CBW19975.1  A0A0H3NUD9  wzxE  416 aa hypothetical lipopolysaccharide biosynthesis protein 2.6e-7 ●●●●○ -3.11 -3.10707572256718
Vibrio parahaemolyticus RIMD 2210633  VP_0146  BAC58409.1  Q87TC4  nfuA  194 aa conserved hypothetical protein 0.0028 ●●●●○ -3.11 -3.10521821697976
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1981  NP_231615.2  Q9KQL7  183 aa hypothetical protein 1.5e-12 ●●●●○ -3.1 -3.10457178394925
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4281  WP_000899636.1  E8XKG6  596 aa aryl-sulfate sulfotransferase 2.9e-8 ●●●●○ -3.1 -3.10384128317779
Serratia marcescens Strain UMH9  BVG96_10420  ASL98008.1  334 aa Holliday junction branch migration DNA helicase RuvB 0.013 ●●●●○ -3.1 -3.09809792112797
Streptococcus pyogenes M1 5448  SP5448_00065  WP_010921768.1  659 aa ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein 0.0021 ●●●●○ -3.1 -3.09760275508381
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0013  NP_232414.1  Q9KNF1  817 aa maltodextrin phosphorylase 2.2e-9 ●●●●○ -3.1 -3.09677796846748
Acinetobacter baumannii ATCC 17978  A1S_1582  ABO12009.2  221 aa transcriptional regulator Cro/CI family 3.4e-14 ●●●●○ -3.09 -3.09129564447933
Streptococcus pyogenes M1 5448  SP5448_06635  WP_002994426.1  85 aa DUF1146 domain-containing protein 0.00065 ●●●●○ -3.09 -3.08991206309929
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0995  WP_000917564.1  E8XDG0  52 aa hypothetical protein 9.7e-24 ●●●●○ -3.09 -3.08807433149994
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1321  WP_000078785.1  E8XGC3  celF  451 aa 6-phospho-beta-glucosidase 1.0e-23 ●●●●○ -3.09 -3.08696108795443
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0251  NP_229908.1  Q9KV99  825 aa acyl protein synthase/acyl-CoA reductase RfbN 5.9e-13 ●●●●○ -3.09 -3.08502134679006
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0958  WP_001145561.1  E8XCS8  319 aa SPI-2 type III secretion system effector SopD2 1.2e-23 ●●●●○ -3.08 -3.08288365361731
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3298  WP_000017678.1  E8XAJ8  hybB  392 aa Ni/Fe-hydrogenase cytochrome b subunit 1.4e-7 ●●●●○ -3.08 -3.08259610490099
Vibrio parahaemolyticus RIMD 2210633  VP_2348  BAC60611.1  Q87MA9  nqrD  210 aa sodium-translocating NADH-quinone reductase, subunit D 0.003 ●●●●○ -3.08 -3.08117865869861
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4283  WP_000852810.1  E8XKG8  metJ  105 aa met regulon transcriptional regulator MetJ 6.1e-8 ●●●●○ -3.08 -3.08068565613196
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0359  WP_002859438.1  A0A0H3PAV1  258 aa flagellar motor protein MotA 0.0018 ●●●●○ -3.08 -3.07987459326
Vibrio parahaemolyticus RIMD 2210633  VP_2567  BAC60830.1  Q87LP4  932 aa sensor histidine kinase/response regulator 0.0031 ●●●●○ -3.08 -3.07702408319809
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0371  WP_000910371.1  E8XJQ5  mod  652 aa site-specific DNA-methyltransferase 0.00024 ●●●●○ -3.08 -3.07639452274794
Acinetobacter baumannii ATCC 17978  A1S_2359  ABO12778.2  A3M784  trpD  349 aa anthranilate phosphoribosyltransferase 4.5e-26 ●●●●○ -3.08 -3.07594695221736
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0303  WP_000272655.1  E8XIV6  rhs1  1198 aa hypothetical protein 2.8e-22 ●●●●○ -3.07 -3.07496526009508
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2084  AIK80689.1  833 aa copper-translocating P-type ATPase <1e-323 ●●●●○ -3.07 -3.07494055055066
Vibrio parahaemolyticus RIMD 2210633  VPA_0416  BAC61759.1  Q87J37  369 aa hypothetical protein 0.0044 ●●●●○ -3.07 -3.07392419528727
Acinetobacter baumannii ATCC 17978  A1S_0469  ABO10924.2  195 aa hypothetical protein 2.3e-59 ●●●●○ -3.07 -3.07053773607358
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0576  NP_230227.1  Q9KUE5  211 aa stringent starvation protein A 9.9e-15 ●●●●○ -3.07 -3.07050295131631
Acinetobacter baumannii ATCC 17978  A1S_2963  ABO13366.2  373 aa phosphoribosylaminoimidazole carboxylase ATPase subunit 3.9e-22 ●●●●○ -3.07 -3.07031229099619
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4492  WP_000978690.1  E8X9U7  adiA  756 aa arginine decarboxylase 2.8e-43 ●●●●○ -3.07 -3.06758529882814
Vibrio parahaemolyticus RIMD 2210633  VP_0593  BAC58856.1  Q87S31  267 aa inositol monophosphate family protein 0.0032 ●●●●○ -3.07 -3.06518875423978
Acinetobacter baumannii ATCC 17978  A1S_2079  ABO12506.2  411 aa putative mechanosensitive ion channel 4.0e-17 ●●●●○ -3.06 -3.06478104572618
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4098  WP_000866685.1  E8XIN0  wecB  376 aa UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) 1.8e-17 ●●●●○ -3.06 -3.06430203120411
Vibrio parahaemolyticus RIMD 2210633  VP_0645  BAC58908.1  Q87RY1  147 aa conserved hypothetical protein 0.0032 ●●●●○ -3.06 -3.06062509390376
Acinetobacter baumannii ATCC 17978  A1S_0603  ABO11054.2  A3M2B0  ihfA  98 aa integration host factor alpha subunit 1.2e-18 ●●●●○ -3.06 -3.05870459602933
Mycobacterium avium subsp. paratuberculosis K10  MAP_2924  AAS05241.1  Q73VT7  nicT  410 aa NicT 0.0012 ●●●●○ -3.06 -3.05702916439454
Vibrio parahaemolyticus RIMD 2210633  VP_0137  BAC58400.1  Q87TD3  198 aa general secretion pathway protein H 0.0033 ●●●●○ -3.06 -3.05669422678045
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4218  WP_000710966.1  E8XKA3  343 aa DUF3829 domain-containing protein 5.1e-21 ●●●●○ -3.06 -3.05667434694759
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1326  CBW17422.1  A0A0H3NCP6  ssrA  920 aa two-component sensor kinase 1.6e-9 ●●●●○ -3.05 -3.05192594812338
Vibrio parahaemolyticus RIMD 2210633  VP_0588  BAC58851.1  Q87S36  tgt  377 aa queuine tRNA-ribosyltransferase 0.0033 ●●●●○ -3.05 -3.05177420596253
Acinetobacter baumannii ATCC 17978  A1S_2875  ABO13281.2  409 aa tryptophan synthase beta chain 2.7e-42 ●●●●○ -3.05 -3.04988621961789
Streptococcus pyogenes M1 5448  SP5448_06890  WP_010922050.1  232 aa MBL fold metallo-hydrolase 8.6e-6 ●●●●○ -3.05 -3.04761325718444
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1575  WP_000152297.1  E8XJ10  osmC  143 aa OsmC family peroxiredoxin 9.0e-9 ●●●●○ -3.04 -3.04363266961084
Acinetobacter baumannii ATCC 17978  A1S_2819  ABO13225.2  A3M8I1  proS  571 aa prolyl-tRNA synthetase 6.5e-28 ●●●●○ -3.04 -3.04302617506557
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3086  AIK81667.1  529 aa phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase <1e-323 ●●●●○ -3.04 -3.0426210463551
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0424  WP_000667305.1  E8XKJ1  tgt  375 aa tRNA guanosine(34) transglycosylase Tgt 4.9e-8 ●●●●○ -3.04 -3.04202695056639
Mycobacterium avium subsp. paratuberculosis K10  MAP_3741  AAS06291.1  Q73TH7  281 aa hypothetical protein 0.0013 ●●●●○ -3.04 -3.03884436656861
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0359  WP_000545421.1  E8XJP3  162 aa hypothetical protein 5.6e-6 ●●●●○ -3.04 -3.03685241713986
Vibrio parahaemolyticus RIMD 2210633  VP_0229  BAC58492.1  Q87T41  187 aa dTDP-4-dehydrorhamnose 3,5-epimerase 0.0035 ●●●●○ -3.04 -3.03615779869016
Streptococcus pyogenes M1 5448  SP5448_03340  WP_002995878.1  218 aa cell division protein SepF 0.0058 ●●●●○ -3.04 -3.03607721920767
Acinetobacter baumannii ATCC 17978  A1S_2876  ABO13282.2  219 aa N-(5'-phosphoribosyl)anthranilate isomerase 5.5e-41 ●●●●○ -3.03 -3.03427642944829
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2850  WP_014344394.1  E8XJ75  369 aa hypothetical protein 1.0e-23 ●●●●○ -3.03 -3.03399644011148
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1144  WP_000100055.1  E8XER7  mdoC  384 aa glucans biosynthesis protein MdoC 6.2e-6 ●●●●○ -3.03 -3.03159476167953
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0041  WP_001094892.1  E8XG60  571 aa arylsulfatase 1.6e-7 ●●●●○ -3.03 -3.02828989212099
Vibrio parahaemolyticus RIMD 2210633  VP_0107  BAC58370.1  Q87TG2  polA  931 aa DNA polymerase I 0.0035 ●●●●○ -3.03 -3.0279905541223
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1346  CBW17442.1  A0A0H3NCR2  ssaL  338 aa Type III secretion system apparatus 9.6e-9 ●●●●○ -3.03 -3.02755845872285
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1134  WP_001137620.1  E8XEQ7  csgG  277 aa curli production assembly/transport protein CsgG 1.7e-16 ●●●●○ -3.03 -3.02752901763613
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0835  NP_230483.1  P29480  tcpT  503 aa toxin co-regulated pilus biosynthesis protein T 8.5e-14 ●●●●○ -3.03 -3.02727692923892
Vibrio parahaemolyticus RIMD 2210633  VP_0428  BAC58691.1  Q87SJ5  cpdA  268 aa cyclic AMP phosphodiesterase 0.0036 ●●●●○ -3.03 -3.02513546026674
Serratia marcescens Strain UMH9  BVG96_19000  ASL99583.1  711 aa Intracellular growth attenuator protein igaA 0.0019 ●●●●○ -3.02 -3.02474289337523
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2370  WP_000944714.1  E8XEB7  294 aa GntR family transcriptional regulator 2.0e-20 ●●●●○ -3.02 -3.02224691387731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3830  AIK82380.1  38 aa hypothetical protein 4.4e-16 ●●●●○ -3.02 -3.02160703906757
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1918  NP_231552.1  Q9KQT0  619 aa peptidyl-prolyl cis-trans isomerse D 1.1e-8 ●●●●○ -3.02 -3.02147503001033
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3169  WP_000036825.1  E8X9J4  409 aa transporter 1.0e-23 ●●●●○ -3.02 -3.02066629539066
Vibrio parahaemolyticus RIMD 2210633  VPA_0662  BAC62004.1  Q87IE5  128 aa transcriptional regulator, MerR family 0.0052 ●●●●○ -3.02 -3.01664231395621
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0249  NP_229906.1  H9L4Q1  471 aa RfbL protein 3.3e-14 ●●●●○ -3.02 -3.01564282087777
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1924  WP_000203014.1  E8X9F9  znuC  251 aa zinc ABC transporter ATP-binding protein ZnuC 3.4e-21 ●●●●○ -3.01 -3.01438279497535
Mycobacterium avium subsp. paratuberculosis K10  MAP_0347c  AAS02664.1  Q744J4  451 aa hypothetical protein 0.0014 ●●●●○ -3.01 -3.0113275222741
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3707  CBW19801.1  A0A0H3NTT7  rpoZ  91 aa DNA-directed RNA polymerase omega chain 5.3e-12 ●●●●○ -3.01 -3.00847596171145
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3425  AIK81982.1  448 aa putative efflux pump outer membrane protein ttgC 2.2e-7 ●●●●○ -3.01 -3.00714698255712
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