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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_22040  ATI08176.1  492 aa colanic acid exporter 1.6e-11 ●●○○○ -1.24 -1.24010139746651
Escherichia coli M12  CO715_11070  ATI06194.1  222 aa 2-deoxyglucose-6-phosphate phosphatase 4.0e-15 ●●○○○ -1.24 -1.23864087536677
Escherichia coli M12  CO715_05625  ATI05252.1  232 aa RNA chaperone ProQ 1.1e-8 ●●○○○ -1.24 -1.23843222935252
Escherichia coli M12  CO715_10480  ATI06086.1  603 aa beta-glucuronidase 1.8e-37 ●●○○○ -1.24 -1.23738899928128
Escherichia coli M12  CO715_11305  ATI06238.1  252 aa DeoR/GlpR transcriptional regulator 2.0e-9 ●●○○○ -1.24 -1.23571983116729
Escherichia coli M12  CO715_08705  ATI05787.1  531 aa ABC-F family ATPase 6.5e-6 ●●○○○ -1.24 -1.23530253913879
Escherichia coli M12  CO715_09245  ATI05880.1  200 aa cob(I)yrinic acid a,c-diamide adenosyltransferase 0.00025 ●●○○○ -1.24 -1.23509389312454
Escherichia coli M12  CO715_21995  ATI08167.1  248 aa colanic acid biosynthesis glycosyltransferase WcaE 5.2e-99 ●●○○○ -1.23 -1.23488524711029
Escherichia coli M12  CO715_18980  ATI07615.1  313 aa spermidine/putrescine ABC transporter permease 2.4e-13 ●●○○○ -1.23 -1.23467660109604
Escherichia coli M12  CO715_17480  ATI07351.1  1180 aa exodeoxyribonuclease V subunit beta 1.9e-11 ●●○○○ -1.23 -1.2344679550818
Escherichia coli M12  CO715_19240  ATI08866.1  410 aa sensor domain-containing diguanylate cyclase 3.0e-32 ●●○○○ -1.23 -1.2336333710248
Escherichia coli M12  CO715_16305  ATI07138.1  313 aa ribosomal RNA small subunit methyltransferase H 9.9e-20 ●●○○○ -1.23 -1.23342472501055
Escherichia coli M12  CO715_22500  ATI08256.1  334 aa dipeptide ABC transporter ATP-binding protein 0.0013 ●●○○○ -1.23 -1.23342472501055
Escherichia coli M12  CO715_01745  ATI04564.1  150 aa phosphonate C-P lyase system protein PhnG 9.1e-15 ●●○○○ -1.23 -1.23259014095356
Escherichia coli M12  CO715_19545  ATI07721.1  55 aa hypothetical protein 4.9e-8 ●●○○○ -1.23 -1.23154691088231
Escherichia coli M12  CO715_06900  ATI05466.1  304 aa metal ABC transporter substrate-binding protein 2.5e-59 ●●○○○ -1.23 -1.23133826486806
Escherichia coli M12  CO715_09025  ATI05847.1  262 aa molybdenum-dependent transcriptional regulator 0.001 ●●○○○ -1.23 -1.23112961885381
Escherichia coli M12  CO715_15490  ATI06991.1  161 aa ribonuclease E activity regulator RraA 4.5e-10 ●●○○○ -1.23 -1.23092097283956
Escherichia coli M12  CO715_19915  ATI07784.1  152 aa transcriptional regulator 2.1e-18 ●●○○○ -1.23 -1.23071232682532
Escherichia coli M12  CO715_07390  ATI05553.1  220 aa hypothetical protein 1.1e-6 ●●○○○ -1.23 -1.22966909675407
Escherichia coli M12  CO715_13795  ATI06685.1  500 aa sugar ABC transporter ATP-binding protein 4.9e-19 ●●○○○ -1.23 -1.22904315871133
Escherichia coli M12  CO715_20080  ATI07816.1  325 aa thiamine-phosphate kinase 0.011 ●●○○○ -1.23 -1.22904315871133
Escherichia coli M12  CO715_00090  ATI04273.1  281 aa sulfurtransferase 3.1e-51 ●●○○○ -1.23 -1.22862586668283
Escherichia coli M12  CO715_15560  ATI07003.1  296 aa methylenetetrahydrofolate reductase 4.0e-13 ●●○○○ -1.23 -1.22841722066858
Escherichia coli M12  CO715_10275  ATI06051.1  404 aa starvation-sensing protein RspA 1.5e-46 ●●○○○ -1.23 -1.22820857465433
Escherichia coli M12  CO715_19300  ATI07673.1  343 aa mechanosensitive ion channel protein MscS 1.5e-69 ●●○○○ -1.23 -1.22758263661158
Escherichia coli M12  CO715_11285  ATI06235.1  618 aa signal peptide peptidase SppA 2.3e-132 ●●○○○ -1.23 -1.22716534458309
Escherichia coli M12  CO715_10085  ATI06024.1  68 aa hypothetical protein 3.9e-24 ●●○○○ -1.23 -1.22695669856884
Escherichia coli M12  CO715_11260  ATI06230.1  651 aa DNA topoisomerase III 0.00028 ●●○○○ -1.23 -1.22633076052609
Escherichia coli M12  CO715_05565  ATI05243.1  218 aa carbon-nitrogen hydrolase family protein 0.003 ●●○○○ -1.23 -1.22570482248334
Escherichia coli M12  CO715_01295  ATI04487.1  212 aa DUF1190 domain-containing protein 3.7e-7 ●●○○○ -1.23 -1.22528753045485
Escherichia coli M12  CO715_19525  ATI07717.1  254 aa phosphatidylglycerophosphatase B 4.4e-6 ●●○○○ -1.22 -1.22445294639785
Escherichia coli M12  CO715_02830  ATI04765.1  111 aa ethanolamine utilization protein EutS 5.9e-15 ●●○○○ -1.22 -1.2242443003836
Escherichia coli M12  CO715_13345  ATI06607.1  294 aa adenine-specific DNA-methyltransferase 9.4e-7 ●●○○○ -1.22 -1.2238270083551
Escherichia coli M12  CO715_13755  ATI06677.1  154 aa anaerobic ribonucleoside-triphosphate reductase-activating protein 9.5e-13 ●●○○○ -1.22 -1.22361836234085
Escherichia coli M12  CO715_04855  ATI05120.1  949 aa two-component system sensor histidine kinase RcsC 1.0e-34 ●●○○○ -1.22 -1.22340971632661
Escherichia coli M12  CO715_09430  ATI05913.1  225 aa two-component system response regulator KdpE 2.6e-10 ●●○○○ -1.22 -1.22340971632661
Escherichia coli M12  CO715_05680  ATI05261.1  106 aa hypothetical protein 5.7e-41 ●●○○○ -1.22 -1.22320107031236
Escherichia coli M12  CO715_15630  ATI07017.1  883 aa phosphoenolpyruvate carboxylase 7.1e-25 ●●○○○ -1.22 -1.22174054821262
Escherichia coli M12  CO715_05030  ATI05152.1  356 aa histidinol-phosphate transaminase 1.1e-16 ●●○○○ -1.22 -1.22132325618412
Escherichia coli M12  CO715_04065  ATI04989.1  268 aa nitrite transporter NirC 0.036 ●●○○○ -1.22 -1.22132325618412
Escherichia coli M12  CO715_17700  ATI07390.1  110 aa hypothetical protein 2.5e-41 ●●○○○ -1.22 -1.22069731814137
Escherichia coli M12  CO715_21820  ATI08135.1  150 aa PTS galactitol transporter subunit IIA 2.5e-102 ●●○○○ -1.22 -1.22028002611287
Escherichia coli M12  CO715_16165  ATI07111.1  284 aa protein AmpE 1.1e-7 ●●○○○ -1.22 -1.22007138009862
Escherichia coli M12  CO715_10920  ATI06164.1  254 aa electron transfer flavoprotein 0.0006 ●●○○○ -1.22 -1.22007138009862
Escherichia coli M12  CO715_21685  ATI08109.1  759 aa hypothetical protein 2.7e-44 ●●○○○ -1.22 -1.21840221198463
Escherichia coli M12  CO715_21560  ATI08088.1  231 aa CidB/LrgB family autolysis modulator 0.0039 ●●○○○ -1.22 -1.2161071058279
Escherichia coli M12  CO715_20670  ATI07925.1  129 aa curli production assembly/transport component CsgE 1.6e-26 ●●○○○ -1.22 -1.21589845981365
Escherichia coli M12  CO715_20805  ATI07948.1  186 aa hypothetical protein 2.5e-13 ●●○○○ -1.22 -1.2152725217709
Escherichia coli M12  CO715_21460  ATI08068.1  293 aa LysR family transcriptional regulator 1.2e-82 ●●○○○ -1.21 -1.2148552297424
Escherichia coli M12  CO715_21350  ATI08047.1  364 aa ABC transporter permease 4.3e-9 ●●○○○ -1.21 -1.21464658372815
Escherichia coli M12  CO715_08635  ATI05774.1  512 aa glutathione ABC transporter substrate-binding protein GsiB 5.7e-27 ●●○○○ -1.21 -1.21402064568541
Escherichia coli M12  CO715_06880  ATI05463.1  50 aa isocitrate dehydrogenase 2.9e-14 ●●○○○ -1.21 -1.21214283155717
Escherichia coli M12  CO715_03045  ATI04805.1  332 aa bile acid:sodium symporter 2.4e-9 ●●○○○ -1.21 -1.21193418554292
Escherichia coli M12  CO715_22545  ATI08262.1  134 aa hypothetical protein 2.5e-7 ●●○○○ -1.21 -1.21193418554292
Escherichia coli M12  CO715_03970  ATI04971.1  134 aa DUF2531 domain-containing protein 0.0037 ●●○○○ -1.21 -1.21193418554292
Escherichia coli M12  CO715_18655  ATI07560.1  328 aa MBL fold hydrolase 3.1e-50 ●●○○○ -1.21 -1.21130824750017
Escherichia coli M12  CO715_20755  ATI07938.1  408 aa multidrug resistance protein MdtG 0.00016 ●●○○○ -1.21 -1.21109960148592
Escherichia coli M12  CO715_05295  ATI05195.1  142 aa universal stress protein UspC 7.2e-11 ●●○○○ -1.21 -1.21047366344318
Escherichia coli M12  CO715_02750  ATI04751.1  287 aa neutral zinc metallopeptidase 6.4e-12 ●●○○○ -1.21 -1.20984772540043
Escherichia coli M12  CO715_10305  ATI06056.1  101 aa hypothetical protein 1.5e-7 ●●○○○ -1.21 -1.20880449532919
Escherichia coli M12  CO715_00365  ATI04323.1  290 aa aldose 1-epimerase 0.0024 ●●○○○ -1.21 -1.20817855728644
Escherichia coli M12  CO715_10355  ATI06064.1  417 aa MFS transporter 9.4e-8 ●●○○○ -1.21 -1.20734397322944
Escherichia coli M12  CO715_05080  ATI05160.1  388 aa serine-type D-Ala-D-Ala carboxypeptidase DacD 9.0e-48 ●●○○○ -1.21 -1.2063007431582
Escherichia coli M12  CO715_23760  ATI08458.1  227 aa DNA-binding response regulator 5.6e-26 ●●○○○ -1.21 -1.20525751308696
Escherichia coli M12  CO715_21735  ATI08118.1  181 aa hypothetical protein 1.5e-235 ●●○○○ -1.21 -1.20504886707271
Escherichia coli M12  CO715_03310  ATI04849.1  246 aa hypothetical protein 2.5e-47 ●●○○○ -1.2 -1.20484022105846
Escherichia coli M12  CO715_17250  ATI07310.1  261 aa oxidoreductase 2.4e-20 ●●○○○ -1.2 -1.20484022105846
Escherichia coli M12  CO715_18640  ATI07557.1  400 aa ERCC4 helicase 6.5e-20 ●●○○○ -1.2 -1.20463157504421
Escherichia coli M12  CO715_15360  ATI06970.1  312 aa HTH-type transcriptional activator RhaR 0.00092 ●●○○○ -1.2 -1.20421428301571
Escherichia coli M12  CO715_08130  ATI05682.1  297 aa hypothetical protein 7.3e-35 ●●○○○ -1.2 -1.20400563700146
Escherichia coli M12  CO715_09355  ATI05899.1  218 aa hypothetical protein 0.00039 ●●○○○ -1.2 -1.20337969895872
Escherichia coli M12  CO715_21565  ATI08089.1  132 aa hypothetical protein 6.2e-5 ●●○○○ -1.2 -1.20296240693022
Escherichia coli M12  CO715_20415  ATI07880.1  314 aa 2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase 8.9e-44 ●●○○○ -1.2 -1.20129323881623
Escherichia coli M12  CO715_15635  ATI07018.1  383 aa acetylornithine deacetylase 2.5e-7 ●●○○○ -1.2 -1.19983271671648
Escherichia coli M12  CO715_20895  ATI07966.1  313 aa flagellar assembly peptidoglycan hydrolase FlgJ 0.00016 ●●○○○ -1.2 -1.19962407070224
Escherichia coli M12  CO715_05400  ATI05213.1  809 aa molybdopterin guanine dinucleotide-containing S/N-oxide reductase 5.2e-10 ●●○○○ -1.2 -1.19920677867374
Escherichia coli M12  CO715_21935  ATI08156.1  1105 aa diguanylate cyclase 1.9e-49 ●●○○○ -1.2 -1.19837219461674
Escherichia coli M12  CO715_03395  ATI04864.1  156 aa fimbrial protein 0.00011 ●●○○○ -1.2 -1.19816354860249
Escherichia coli M12  CO715_04085  ATI04993.1  190 aa peptidylprolyl isomerase A 8.9e-5 ●●○○○ -1.2 -1.19753761055975
Escherichia coli M12  CO715_03390  ATI04863.1  204 aa fimbrial protein 0.00053 ●●○○○ -1.2 -1.19712031853125
Escherichia coli M12  CO715_09310  ATI05891.1  427 aa type II citrate synthase 3.0e-10 ●●○○○ -1.2 -1.196911672517
Escherichia coli M12  CO715_06635  ATI05419.1  270 aa SAM-dependent methyltransferase 1.8e-5 ●●○○○ -1.2 -1.196911672517
Escherichia coli M12  CO715_07040  ATI05491.1  299 aa Replication protein O 1.9e-9 ●●○○○ -1.2 -1.19670302650275
Escherichia coli M12  CO715_06260  ATI05357.1  253 aa AraC family transcriptional regulator 1.1e-186 ●●○○○ -1.19 -1.19294739824627
Escherichia coli M12  CO715_13220  ATI06583.1  90 aa hypothetical protein 0.034 ●●○○○ -1.19 -1.19294739824627
Escherichia coli M12  CO715_23930  ATI08489.1  108 aa thiosulfate sulfurtransferase 0.039 ●●○○○ -1.19 -1.19294739824627
Escherichia coli M12  CO715_13970  ATI06715.1  274 aa hypothetical protein 1.4e-26 ●●○○○ -1.19 -1.19044364607529
Escherichia coli M12  CO715_20570  ATI07907.1  212 aa transcriptional regulator 2.8e-31 ●●○○○ -1.19 -1.19023500006104
Escherichia coli M12  CO715_08440  ATI05737.1  243 aa arginine ABC transporter substrate-binding protein 3.4e-5 ●●○○○ -1.19 -1.18940041600404
Escherichia coli M12  CO715_06060  ATI05320.1  462 aa succinate-semialdehyde dehydrogenase 1.4e-47 ●●○○○ -1.19 -1.18898312397554
Escherichia coli M12  CO715_04985  ATI05144.1  468 aa phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) 3.2e-29 ●●○○○ -1.19 -1.18898312397554
Escherichia coli M12  CO715_21125  ATI08009.1  452 aa MFS transporter 7.5e-5 ●●○○○ -1.19 -1.18856583194705
Escherichia coli M12  CO715_12095  ATI06384.1  560 aa glycolate permease GlcA 2.2e-27 ●●○○○ -1.19 -1.1879398939043
Escherichia coli M12  CO715_00040  ATI04263.1  162 aa Fe-S cluster assembly transcriptional regulator IscR 0.0012 ●●○○○ -1.19 -1.1875226018758
Escherichia coli M12  CO715_20240  ATI07846.1  152 aa DUF188 domain-containing protein 1.1e-18 ●●○○○ -1.19 -1.1871053098473
Escherichia coli M12  CO715_08495  ATI05748.1  377 aa polyamine ABC transporter ATP-binding protein 2.1e-95 ●●○○○ -1.18 -1.18334968159082
Escherichia coli M12  CO715_22305  ATI08223.1  127 aa autonomous glycyl radical cofactor GrcA 0.00056 ●●○○○ -1.18 -1.18272374354808
Escherichia coli M12  CO715_11515  ATI06278.1  119 aa DUF1889 domain-containing protein 2.2e-12 ●●○○○ -1.18 -1.18251509753383
Escherichia coli M12  CO715_08750  ATI05795.1  167 aa DNA starvation/stationary phase protection protein 1.0e-6 ●●○○○ -1.18 -1.18188915949108
Retrieved entries 801–900 out of 3,550 total in 47.4 ms (Link to these results)