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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1634  AIK80254.1  243 aa phage capsid scaffolding (GPO) serine peptidase family protein 0.00033 ○○○○○ 0.31 0.314103898778168
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4383  AIK82926.1  435 aa glucarate dehydratase <1e-323 ○○○○○ 0.31 0.314260829909584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4650  AIK83184.1  1649 aa alpha-2-macroglobulin MG1 domain protein <1e-323 ○○○○○ 0.32 0.315866530246686
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1697  AIK80317.1  86 aa hypothetical protein 0.0013 ○○○○○ 0.32 0.316211491973559
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4298  AIK82843.1  106 aa hypothetical protein 2.7e-5 ○○○○○ 0.32 0.317215151279799
Escherichia coli M12  CO715_03260  ATI04840.1  307 aa aminoimidazole riboside kinase 0.04 ○○○○○ 0.32 0.317441098901234
Escherichia coli M12  CO715_05290  ATI05194.1  474 aa alpha,alpha-trehalose-phosphate synthase 0.00024 ○○○○○ 0.32 0.317649744915483
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2296  AIK80900.1  465 aa dihydrolipoyl dehydrogenase <1e-323 ○○○○○ 0.32 0.317937590090269
Escherichia coli M12  CO715_11365  ATI06250.1  248 aa MltA-interacting protein 0.0019 ○○○○○ 0.32 0.318067036943981
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0402  NP_230056.1  Q9KUV9  559 aa MSHA biogenesis protein MshL 5.8e-6 ○○○○○ 0.32 0.318112293589539
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4359  AIK82902.1  423 aa H+ symporter permease 5.6e-7 ○○○○○ 0.32 0.318665411240112
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2013  AIK80619.1  390 aa major Facilitator Superfamily protein 2.6e-13 ○○○○○ 0.32 0.319252541646833
Escherichia coli M12  CO715_18240  ATI07486.1  520 aa DUF1266 domain-containing protein 4.9e-5 ○○○○○ 0.32 0.32015349708647
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2008  AIK80614.1  499 aa amino acid permease family protein <1e-323 ○○○○○ 0.32 0.321452227254515
Porphyromonas gingivalis ATCC 33277  PGN_0322  WP_005874255.1  B2RHJ6  297 aa hypothetical protein 3.9e-11 ○○○○○ 0.32 0.321941107810943
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0299  NP_232695.1  Q9KMN2  147 aa hypothetical protein 0.04 ○○○○○ 0.32 0.322054257782485
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1806  AIK80419.1  241 aa hypothetical protein 0.00037 ○○○○○ 0.32 0.323863449022571
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2408  AIK81005.1  657 aa type II secretion system protein D <1e-323 ○○○○○ 0.32 0.324075941327004
Escherichia coli M12  CO715_09365  ATI05901.1  493 aa dipeptide permease D 0.035 ○○○○○ 0.32 0.324535063385696
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4269  AIK82814.1  108 aa cupin 2, conserved barrel domain protein 0.016 ○○○○○ 0.32 0.324785864571044
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4055  AIK82602.1  288 aa glutathione S-transferase, C-terminal domain protein 6.4e-15 ○○○○○ 0.33 0.325337253401275
Escherichia coli M12  CO715_16515  ATI07177.1  313 aa protein FixB 0.0055 ○○○○○ 0.33 0.325369647442691
Escherichia coli M12  CO715_16415  ATI07157.1  566 aa ribulokinase 0.0073 ○○○○○ 0.33 0.325369647442691
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4239  AIK82783.1  318 aa high-affinity nickel-transport family protein 1.3e-15 ○○○○○ 0.33 0.325388876949138
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2263  AIK80868.1  541 aa putative receptor <1e-323 ○○○○○ 0.33 0.326324287180677
Porphyromonas gingivalis ATCC 33277  PGN_1110  WP_012458037.1  B2RJT4  211 aa IS5/IS1182 family transposase 2.9e-6 ○○○○○ 0.33 0.32734400235132
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4120  AIK82666.1  254 aa homoserine dehydrogenase, NAD binding domain protein <1e-323 ○○○○○ 0.33 0.329100303779074
Escherichia coli M12  CO715_09870  ATI05988.1  406 aa phosphoadenosine phosphosulfate reductase 0.01 ○○○○○ 0.33 0.329125275699171
Escherichia coli M12  CO715_01815  ATI04578.1  343 aa multidrug resistance protein MdtN 0.0053 ○○○○○ 0.33 0.329751213741917
Escherichia coli M12  CO715_02130  ATI04635.1  212 aa hypothetical protein 0.0067 ○○○○○ 0.33 0.330377151784664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1751  AIK80371.1  403 aa blue light-responsive regulator of YcgE 1.0e-9 ○○○○○ 0.33 0.331000460871904
Escherichia coli M12  CO715_24580  ATI08605.1  294 aa LysR family transcriptional regulator 0.00014 ○○○○○ 0.33 0.331211735841659
Escherichia coli M12  CO715_08715  ATI05789.1  372 aa anion transporter 0.0027 ○○○○○ 0.33 0.331837673884406
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2852  AIK81441.1  669 aa beta-galactosidase trimerization domain protein <1e-323 ○○○○○ 0.33 0.331858548314925
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2286  AIK80890.1  149 aa hypothetical protein 0.00035 ○○○○○ 0.33 0.332082707436795
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2542  AIK81139.1  446 aa citrate-sodium symporter 7.6e-15 ○○○○○ 0.33 0.332348829801214
Escherichia coli M12  CO715_09240  ATI05879.1  550 aa fumarate hydratase 1.9e-7 ○○○○○ 0.33 0.332672257941401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2633  AIK81227.1  481 aa altronate oxidoreductase <1e-323 ○○○○○ 0.33 0.332864100018646
Escherichia coli M12  CO715_22380  ATI08235.1  194 aa hypothetical protein 0.0006 ○○○○○ 0.33 0.33288090395565
Escherichia coli M12  CO715_04280  ATI05031.1  256 aa thiazole synthase 0.0049 ○○○○○ 0.33 0.333089549969899
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4884  AIK83411.1  885 aa putative 2-component sensor protein 6.9e-13 ○○○○○ 0.33 0.334380716331983
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2535  NP_232163.1  Q9KP44  447 aa peptidase PmbA 0.039 ○○○○○ 0.33 0.33482656226265
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3370  AIK81927.1  430 aa phosphoglycerate transporter family protein <1e-323 ○○○○○ 0.34 0.335525745187109
Escherichia coli M12  CO715_22440  ATI08246.1  779 aa cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB 9.0e-13 ○○○○○ 0.34 0.335801948155134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4534  AIK83072.1  342 aa fimbrial family protein <1e-323 ○○○○○ 0.34 0.335872969872051
Escherichia coli M12  CO715_22805  ATI08306.1  225 aa helix-turn-helix transcriptional regulator 2.3e-7 ○○○○○ 0.34 0.338097054311872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2674  AIK81268.1  383 aa 2-hydroxyglutaryl-CoA dehydratase, D-component family protein <1e-323 ○○○○○ 0.34 0.338302258474216
Escherichia coli M12  CO715_04105  ATI04997.1  406 aa aspartate aminotransferase family protein 0.026 ○○○○○ 0.34 0.338931638368867
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4985  AIK83511.1  425 aa polyol permease family protein 1.8e-12 ○○○○○ 0.34 0.339651019742544
Porphyromonas gingivalis ATCC 33277  PGN_0065  WP_012457210.1  B2RGT9  traG  833 aa TraG family conjugative transposon ATPase 2.6e-13 ○○○○○ 0.34 0.341171113761066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1191  AIK79814.1  206 aa telomere recombination family protein 0.00035 ○○○○○ 0.34 0.341861044839137
Escherichia coli M12  CO715_20965  ATI07980.1  244 aa beta-ketoacyl-ACP reductase 0.044 ○○○○○ 0.34 0.3420613285826
Escherichia coli M12  CO715_14315  ATI06777.1  445 aa heme anaerobic degradation radical SAM methyltransferase ChuW/HutW 0.014 ○○○○○ 0.34 0.342687266625346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1579  AIK80199.1  299 aa hypothetical protein 0.00051 ○○○○○ 0.34 0.342985380519538
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3363  AIK81920.1  270 aa sugar phosphatase <1e-323 ○○○○○ 0.34 0.343357298458281
Escherichia coli M12  CO715_23495  ATI08413.1  140 aa hypothetical protein 0.005 ○○○○○ 0.34 0.344356434739337
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3372  AIK81929.1  110 aa hypothetical protein 0.00084 ○○○○○ 0.34 0.344470345192025
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4736  AIK83270.1  191 aa hypothetical protein <1e-323 ○○○○○ 0.34 0.344807103660926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3302  AIK81863.1  299 aa acyltransferase family protein <1e-323 ○○○○○ 0.35 0.345156139461512
Escherichia coli M12  CO715_04450  ATI05055.1  495 aa MATE family multidrug exporter 0.023 ○○○○○ 0.35 0.345399664810582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2840  AIK81429.1  332 aa yjfF <1e-323 ○○○○○ 0.35 0.345553890341795
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0783  NP_230432.1  Q9KTV4  660 aa hypothetical protein 1.4e-7 ○○○○○ 0.35 0.345627822322124
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2295  AIK80899.1  511 aa e3 binding domain protein 0.0006 ○○○○○ 0.35 0.345700284621567
Porphyromonas gingivalis ATCC 33277  PGN_0925  WP_012457885.1  B2RJ99  313 aa mobilization protein 1.1e-9 ○○○○○ 0.35 0.345737523340452
Escherichia coli M12  CO715_23580  ATI08429.1  593 aa glyoxylate carboligase 0.00012 ○○○○○ 0.35 0.346234248867577
Escherichia coli M12  CO715_15825  ATI07048.1  296 aa protein RarD 0.0013 ○○○○○ 0.35 0.346860186910324
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1309  AIK79932.1  295 aa manganese containing catalase family protein <1e-323 ○○○○○ 0.35 0.346938859471112
Escherichia coli M12  CO715_17780  ATI07406.1  249 aa AraC family transcriptional regulator 9.9e-13 ○○○○○ 0.35 0.34748612495307
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1519  AIK80139.1  871 aa aminopeptidase N 2.5e-14 ○○○○○ 0.35 0.348371394021543
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2076  AIK80681.1  207 aa tesA 7.8e-16 ○○○○○ 0.35 0.348689626200347
Escherichia coli M12  CO715_17650  ATI07383.1  163 aa CesD/SycD/LcrH family type III secretion system chaperone 0.001 ○○○○○ 0.35 0.348946647052812
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3024  AIK81609.1  526 aa bacterial extracellular solute-binding, 3 familyprotein <1e-323 ○○○○○ 0.35 0.349118474692025
Porphyromonas gingivalis ATCC 33277  PGN_0561  WP_080504398.1  B2RI85  prtT  48 aa DUF1661 domain-containing protein <1e-323 ○○○○○ 0.35 0.349769284119935
Porphyromonas gingivalis ATCC 33277  PGN_0564  WP_004585361.1  B2RI88  sod  191 aa superoxide dismutase <1e-323 ○○○○○ 0.35 0.349769284119935
Porphyromonas gingivalis ATCC 33277  PGN_0561  WP_080504440.1  B2RI85  prtT  824 aa T9SS type A sorting domain-containing protein <1e-323 ○○○○○ 0.35 0.349769284119935
Escherichia coli M12  CO715_01725  ATI04560.1  262 aa phosphonate ABC transporter ATP-binding protein 0.0044 ○○○○○ 0.35 0.349781231109808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4953  AIK83479.1  581 aa D-lactate dehydrogenase <1e-323 ○○○○○ 0.35 0.349986220971391
Escherichia coli M12  CO715_22640  ATI08278.1  157 aa protein CreA 4.4e-7 ○○○○○ 0.35 0.350824461181052
Escherichia coli M12  CO715_24710  ATI08628.1  157 aa tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL 0.0013 ○○○○○ 0.35 0.350824461181052
Escherichia coli M12  CO715_14170  ATI06750.1  207 aa hypothetical protein 4.3e-6 ○○○○○ 0.35 0.351867691252296
Escherichia coli M12  CO715_02320  ATI04669.1  398 aa 2-amino-3-ketobutyrate CoA ligase 0.0035 ○○○○○ 0.35 0.352076337266545
Escherichia coli CFT073  c1474  AAN79943.1  A0A0H2V5P4  221 aa Hypothetical protein ybcY precursor 6.2e-17 ○○○○○ 0.35 0.352172457803436
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4979  AIK83505.1  535 aa FGGY carbohydrate kinase domain-containing protein <1e-323 ○○○○○ 0.35 0.352256023065227
Escherichia coli M12  CO715_02295  ATI04664.1  514 aa 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.048 ○○○○○ 0.35 0.352493629295043
Escherichia coli M12  CO715_13605  ATI06649.1  343 aa L-idonate 5-dehydrogenase 9.8e-5 ○○○○○ 0.35 0.352702275309292
Escherichia coli M12  CO715_01245  ATI04477.1  154 aa ascorbate-specific phosphotransferase enzyme IIA component 0.00018 ○○○○○ 0.35 0.352910921323541
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5120  AIK83646.1  3163 aa methyltransferase domain protein <1e-323 ○○○○○ 0.35 0.353085341046847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3733  AIK82288.1  289 aa phosphoribulokinase / Uridine kinase family protein <1e-323 ○○○○○ 0.35 0.354529808032618
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3609  AIK82164.1  473 aa yhiP peptide POT transporter <1e-323 ○○○○○ 0.35 0.354998274877962
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3511  AIK82067.1  262 aa glycosyl transferase 2 family protein 1.9e-11 ○○○○○ 0.36 0.355085026150923
Escherichia coli M12  CO715_23780  ATI08462.1  407 aa efflux RND transporter periplasmic adaptor subunit 0.0003 ○○○○○ 0.36 0.355206027480278
Escherichia coli M12  CO715_18680  ATI07564.1  390 aa hypothetical protein 0.0067 ○○○○○ 0.36 0.358127071679762
Escherichia coli M12  CO715_22645  ATI08279.1  289 aa right origin-binding protein 0.0084 ○○○○○ 0.36 0.359378947765255
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1788  AIK80401.1  38 aa cyd operon protein YbgT 0.011 ○○○○○ 0.36 0.360524844155659
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2415  AIK81012.1  317 aa type II secretion system (T2SS), K family protein 9.7e-9 ○○○○○ 0.36 0.360585579188524
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1965  AIK80571.1  283 aa bacterial extracellular solute-binding, 3 familyprotein 2.4e-13 ○○○○○ 0.36 0.361226204244941
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1978  AIK80584.1  1030 aa efflux pump membrane transporter BepE <1e-323 ○○○○○ 0.36 0.361630764688336
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2507  AIK81104.1  523 aa thiamine/thiamine pyrophosphate ABC transporter,permease protein <1e-323 ○○○○○ 0.36 0.361649514117401
Escherichia coli M12  CO715_13445  ATI06623.1  47 aa hypothetical protein 2.6e-9 ○○○○○ 0.36 0.364595098121477
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2041  AIK80647.1  494 aa heme ABC exporter, ATP-binding protein CcmA 2.9e-7 ○○○○○ 0.37 0.365347436741581
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