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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1331  AIK79954.1  285 aa potB 0.0014 ○○○○○ 0.42 0.416593990449108
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2161  AIK80766.1  604 aa cytochrome o ubiquinol oxidase, subunit I <1e-323 ○○○○○ 0.42 0.417104361673602
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4970  AIK83496.1  307 aa bacterial regulatory helix-turn-helix, lysR family protein 0.0032 ○○○○○ 0.42 0.417578070877257
Escherichia coli M12  CO715_00840  ATI04407.1  430 aa MFS transporter 0.0021 ○○○○○ 0.42 0.417591185740688
Escherichia coli M12  CO715_01520  ATI04526.1  418 aa L-methionine/branched-chain amino acid transporter 6.0e-5 ○○○○○ 0.42 0.418008477769185
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4087  AIK82633.1  269 aa ABC transporter family protein 9.8e-12 ○○○○○ 0.42 0.418747515633816
Escherichia coli M12  CO715_23005  ATI08342.1  276 aa hypothetical protein 0.00068 ○○○○○ 0.42 0.418843061826181
Escherichia coli M12  CO715_13855  ATI06695.1  303 aa hypothetical protein 0.00049 ○○○○○ 0.42 0.41905170784043
Porphyromonas gingivalis ATCC 33277  PGN_0083  WP_012457227.1  B2RGV7  464 aa DUF3945 domain-containing protein 0.006 ○○○○○ 0.42 0.419427830764738
Escherichia coli M12  CO715_15140  ATI06931.1  196 aa helix-turn-helix transcriptional regulator 1.4e-8 ○○○○○ 0.42 0.419468999868927
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3348  AIK81905.1  388 aa esterase family protein <1e-323 ○○○○○ 0.42 0.419627705713148
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1388  AIK80011.1  194 aa ribosomal-protein-S5-alanine N-acetyltransferase 0.049 ○○○○○ 0.42 0.419886575802851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4411  AIK82954.1  208 aa protein-L-isoaspartate O-methyltransferase 5.0e-12 ○○○○○ 0.42 0.419933152337275
Escherichia coli M12  CO715_05705  ATI05266.1  346 aa minor capsid protein E 0.00031 ○○○○○ 0.42 0.420512229940172
Escherichia coli M12  CO715_17605  ATI07375.1  409 aa transporter 4.1e-6 ○○○○○ 0.42 0.421138167982918
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3821  AIK82371.1  193 aa septum formation protein Maf 0.00045 ○○○○○ 0.42 0.421428224263395
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5085  AIK83611.1  302 aa P-type conjugative transfer protein VirB9 1.1e-10 ○○○○○ 0.42 0.421465496601042
Porphyromonas gingivalis ATCC 33277  PGN_0491  WP_012457551.1  B2RI15  167 aa low molecular weight phosphotyrosine protein phosphatase <1e-323 ○○○○○ 0.42 0.42261462991981
Porphyromonas gingivalis ATCC 33277  PGN_0125  WP_012457265.1  B2RGZ9  319 aa dihydrofolate reductase <1e-323 ○○○○○ 0.42 0.423620384071092
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4426  AIK82969.1  345 aa putative heme/hemoglobin transport protein <1e-323 ○○○○○ 0.42 0.423716558558294
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1920  AIK80526.1  701 aa carbon starvation CstA family protein <1e-323 ○○○○○ 0.42 0.423804662865121
Escherichia coli M12  CO715_23525  ATI08419.1  259 aa iron export permease FetB 0.022 ○○○○○ 0.42 0.424059212182403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1798  AIK80411.1  588 aa succinate dehydrogenase, flavoprotein subunit 0.00014 ○○○○○ 0.43 0.425934800522291
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3063  AIK81648.1  309 aa sodium Bile acid symporter family protein 4.5e-5 ○○○○○ 0.43 0.427194798436555
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4677  AIK83211.1  622 aa type I phosphodiesterase / nucleotide pyrophosphatase family protein 2.9e-8 ○○○○○ 0.43 0.427687857431422
Escherichia coli M12  CO715_15555  ATI07002.1  517 aa bifunctional metallophosphatase/5'-nucleotidase 0.0029 ○○○○○ 0.43 0.42823213246738
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2520  AIK81117.1  541 aa histidine kinase-, DNA gyrase B-, and HSP90-likeATPase family protein <1e-323 ○○○○○ 0.43 0.429146304075259
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0954  NP_233338.1  Q9KKZ6  306 aa chemotaxis protein CheV 0.0045 ○○○○○ 0.43 0.42988790057279
Escherichia coli M12  CO715_00530  ATI04352.1  484 aa xylulokinase 0.044 ○○○○○ 0.43 0.429901300581371
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2038  AIK80644.1  213 aa hypothetical protein 0.0044 ○○○○○ 0.43 0.431297531801456
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5130  AIK83655.1  478 aa MATE efflux family protein 3.8e-7 ○○○○○ 0.43 0.431904882229398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4166  AIK82712.1  238 aa hypothetical protein <1e-323 ○○○○○ 0.43 0.432039534344942
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1294  AIK79917.1  212 aa leuE leucine RhtB transporter 0.019 ○○○○○ 0.43 0.432053916605358
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1436  AIK80057.1  1320 aa putA bifunctional enzyme and transcriptional regulator PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1.4e-5 ○○○○○ 0.43 0.433383333235752
Escherichia coli M12  CO715_15065  ATI06918.1  296 aa AraC family transcriptional regulator 0.015 ○○○○○ 0.43 0.433865574852099
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1275  AIK79897.1  405 aa major Facilitator Superfamily protein 1.6e-6 ○○○○○ 0.43 0.433921014408248
Porphyromonas gingivalis ATCC 33277  PGN_1071  WP_012458002.1  B2RJP5  286 aa hypothetical protein 1.1e-16 ○○○○○ 0.43 0.433967773356307
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2145  NP_231776.1  Q9KQ59  302 aa TyrA protein 0.013 ○○○○○ 0.43 0.434435339167288
Escherichia coli M12  CO715_23225  ATI08380.1  334 aa multidrug DMT transporter permease 0.012 ○○○○○ 0.43 0.434491512894845
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3742  AIK82297.1  276 aa peptidyl-prolyl cis-trans isomerase in protein folding <1e-323 ○○○○○ 0.43 0.434598967382164
Escherichia coli M12  CO715_12545  ATI06461.1  298 aa LysR family transcriptional regulator 0.011 ○○○○○ 0.44 0.435743388980339
Escherichia coli M12  CO715_24350  ATI08566.1  494 aa type VI secretion system contractile sheath large subunit 0.049 ○○○○○ 0.44 0.436160681008836
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3646  AIK82201.1  414 aa tryptophan/tyrosine permease family protein <1e-323 ○○○○○ 0.44 0.436188946082398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4773  AIK83300.1  553 aa indole-3-pyruvate decarboxylase <1e-323 ○○○○○ 0.44 0.436853581392216
Escherichia coli M12  CO715_15965  ATI07075.1  204 aa YigZ family protein 0.021 ○○○○○ 0.44 0.439081725208321
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2615  AIK81209.1  164 aa putative DNA-binding transcriptional regulator 1.7e-14 ○○○○○ 0.44 0.440032874103023
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1002  NP_233386.1  Q9KKU8  239 aa AzlC family protein 0.0071 ○○○○○ 0.44 0.440406151780323
Escherichia coli M12  CO715_15680  ATI07025.1  366 aa tRNA (uridine(54)-C5)-methyltransferase TrmA 0.0018 ○○○○○ 0.44 0.441794123393556
Escherichia coli M12  CO715_24625  ATI08612.1  614 aa selenocysteinyl-tRNA-specific translation elongation factor SelB 0.024 ○○○○○ 0.44 0.442211415422053
Escherichia coli M12  CO715_06280  ATI05361.1  715 aa TonB-dependent receptor 0.016 ○○○○○ 0.44 0.443045999479049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3944  AIK82492.1  127 aa hypothetical protein 0.0065 ○○○○○ 0.44 0.443598032921176
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4256  AIK82801.1  391 aa oligogalacturonate lyase 6.7e-16 ○○○○○ 0.44 0.443774742521783
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5105  AIK83631.1  689 aa tonB-dependent siderophore receptor family protein 7.3e-7 ○○○○○ 0.44 0.443982040974228
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4833  AIK83360.1  199 aa deoxyribonucleoside 5'-monophosphate phosphatase 3.5e-5 ○○○○○ 0.44 0.444772951846868
Escherichia coli M12  CO715_16005  ATI08834.1  866 aa outer membrane usher protein 0.0095 ○○○○○ 0.45 0.445967043678533
Escherichia coli M12  CO715_14475  ATI06808.1  540 aa DUF4049 domain-containing protein 0.047 ○○○○○ 0.45 0.446592981721279
Escherichia coli M12  CO715_06225  ATI05351.1  239 aa fimbrial chaperone protein FimC 0.0012 ○○○○○ 0.45 0.447218919764026
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3828  AIK82378.1  635 aa p-hydroxybenzoic acid efflux pump subunit AaeB <1e-323 ○○○○○ 0.45 0.448012057081488
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4793  AIK83320.1  310 aa N5-glutamine methyltransferase, ribosomal protein L3-specific 8.3e-9 ○○○○○ 0.45 0.448781463390084
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4502  AIK83040.1  390 aa emrA Membrane Fusion Protein 2.2e-16 ○○○○○ 0.45 0.448785224475443
Escherichia coli M12  CO715_09325  ATI05894.1  243 aa fimbrial protein 0.033 ○○○○○ 0.45 0.449722671935012
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1216  NP_230861.1  Q9KSP0  372 aa GGDEF family protein 0.00059 ○○○○○ 0.45 0.449833306496854
Escherichia coli M12  CO715_00940  ATI04423.1  471 aa tryptophanase 0.044 ○○○○○ 0.45 0.449931317949261
Escherichia coli M12  CO715_13295  ATI06597.1  324 aa oxidoreductase 0.047 ○○○○○ 0.45 0.449931317949261
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2312  AIK80916.1  466 aa GABA permease <1e-323 ○○○○○ 0.45 0.450194372326116
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2204  AIK80809.1  463 aa PTS system sugar-specific permease component family protein 0.00013 ○○○○○ 0.45 0.451356958042031
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4438  AIK82981.1  304 aa ROK family protein <1e-323 ○○○○○ 0.45 0.451464422026622
Escherichia coli M12  CO715_20330  ATI07864.1  283 aa taurine dioxygenase 0.014 ○○○○○ 0.45 0.452226424105999
Escherichia coli M12  CO715_18440  ATI07523.1  357 aa hypothetical protein 0.002 ○○○○○ 0.45 0.453686946205741
Escherichia coli M12  CO715_14920  ATI06891.1  328 aa autoinducer 2 ABC transporter substrate-binding protein 0.021 ○○○○○ 0.45 0.453686946205741
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3985  AIK82533.1  267 aa glpF - glycerol MIP channel 1.4e-13 ○○○○○ 0.45 0.453802363739977
Escherichia coli M12  CO715_06230  ATI05352.1  865 aa fimbrial protein 6.2e-6 ○○○○○ 0.45 0.45389559221999
Escherichia coli M12  CO715_07955  ATI05650.1  180 aa type 1 fimbrial protein subunit FimA 0.033 ○○○○○ 0.45 0.454521530262736
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3520  AIK82076.1  157 aa tRNA (cytidine(34)-2'-O)-methyltransferase 0.022 ○○○○○ 0.45 0.454846366166019
Porphyromonas gingivalis ATCC 33277  PGN_0807  WP_039417259.1  B2RIY1  267 aa TatD family deoxyribonuclease <1e-323 ○○○○○ 0.46 0.455036946957539
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2428  AIK81025.1  284 aa pantoate--beta-alanine ligase 0.00014 ○○○○○ 0.46 0.455878876546217
Porphyromonas gingivalis ATCC 33277  PGN_1412  WP_005874035.1  B2RKN6  273 aa purine nucleoside phosphorylase I, inosine and guanosine-specific <1e-323 ○○○○○ 0.46 0.456223043331576
Porphyromonas gingivalis ATCC 33277  PGN_0554  WP_010956341.1  B2RI78  192 aa hypothetical protein 0.00026 ○○○○○ 0.46 0.456223043331576
Porphyromonas gingivalis ATCC 33277  PGN_0162  WP_012457292.1  B2RH36  256 aa hypothetical protein 0.0031 ○○○○○ 0.46 0.456223043331576
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4470  AIK83013.1  482 aa metallo-beta-lactamase superfamily protein <1e-323 ○○○○○ 0.46 0.45798360361027
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4068  AIK82615.1  243 aa gram-negative pili assembly chaperone, C-terminal domain protein <1e-323 ○○○○○ 0.46 0.459264489656737
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1146  AIK79769.1  465 aa hypothetical protein <1e-323 ○○○○○ 0.46 0.460362982782134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3179  AIK81747.1  461 aa amino acid permease family protein <1e-323 ○○○○○ 0.46 0.462558963026276
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1297  AIK79920.1  347 aa L-asparaginase 8.9e-16 ○○○○○ 0.46 0.462884670668015
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4704  AIK83238.1  231 aa phospholipase/Carboxylesterase family protein 0.0065 ○○○○○ 0.46 0.46291055804551
Porphyromonas gingivalis ATCC 33277  PGN_1260  WP_012458148.1  B2RK84  cobQ  498 aa cobyric acid synthase 0.022 ○○○○○ 0.46 0.463756665180932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4725  AIK83259.1  410 aa ethanolamine utilization, EutH family protein <1e-323 ○○○○○ 0.46 0.463814048093385
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4649  AIK83183.1  285 aa 3-mercaptopyruvate sulfurtransferase 0.0021 ○○○○○ 0.47 0.466536893672491
Escherichia coli M12  CO715_00980  ATI04431.1  802 aa type III effector 0.024 ○○○○○ 0.47 0.467040291117668
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5081  AIK83607.1  629 aa type IV secretory system Conjugative DNA transfer family protein 0.0025 ○○○○○ 0.47 0.467041224762432
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4868  AIK83395.1  540 aa glycerol-3-phosphate dehydrogenase, anaerobic, Asubunit 1.9e-8 ○○○○○ 0.47 0.467364551262081
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1253  AIK79876.1  248 aa acid phosphatase <1e-323 ○○○○○ 0.47 0.467935905128275
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0148  NP_232548.2  Q9KN18  1247 aa TagA-like protein 0.034 ○○○○○ 0.47 0.468170604928892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2913  AIK81499.1  244 aa fumarate reductase iron-sulfur protein <1e-323 ○○○○○ 0.47 0.468370878545475
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1682  AIK80302.1  157 aa mntR transcriptional repressor 0.0005 ○○○○○ 0.47 0.469875410512502
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2211  AIK80815.1  300 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 0.47 0.470952505375015
Porphyromonas gingivalis ATCC 33277  PGN_0741  WP_012457745.1  B2RIR5  848 aa TonB-dependent receptor <1e-323 ○○○○○ 0.47 0.471349390654537
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2387  AIK80984.1  128 aa hypothetical protein 0.00086 ○○○○○ 0.47 0.47146603291422
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4768  AIK83296.1  400 aa nucleoside transporter, NupC family protein <1e-323 ○○○○○ 0.47 0.471484357349261
Escherichia coli M12  CO715_17175  ATI07296.1  520 aa type I-E CRISPR-associated protein Cse1/CasA 0.042 ○○○○○ 0.47 0.471630503431143
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