Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0797  WP_000301556.1  E8XB02  gpmA  250 aa 2,3-diphosphoglycerate-dependent phosphoglycerate mutase 0.0045 ●○○○○ -0.57 -0.572989275762483
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2268  NP_231899.2  Q9KPU4  ribH  156 aa 6,7-dimethyl-8-ribityllumazine synthase 0.0036 ●○○○○ -0.57 -0.572399505972335
Acinetobacter baumannii ATCC 17978  A1S_2565  ABO12982.1  382 aa putative transport protein (MFS superfamily) 0.0041 ●○○○○ -0.57 -0.571548071974824
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3212  AIK81780.1  229 aa hdfR transcriptional regulator HdfR transcriptional repressor <1e-323 ●○○○○ -0.57 -0.571112808364823
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2555  NP_232183.1  Q9KP24  173 aa hypothetical protein 1.5e-8 ●○○○○ -0.57 -0.570982977695173
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2285  NP_231916.1  Q9KPS7  505 aa GGDEF family protein 0.00016 ●○○○○ -0.57 -0.570606601739023
Escherichia coli M12  CO715_18775  ATI07579.1  160 aa hypothetical protein 0.034 ●○○○○ -0.57 -0.570556337741919
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3864  AIK82414.1  95 aa putative ribosome-associated, sigma 54 modulation protein 0.0033 ●○○○○ -0.57 -0.570384307153801
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1049  NP_233431.1  Q9KKQ3  292 aa hypothetical protein 0.025 ●○○○○ -0.57 -0.570340954769144
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0988  WP_000301921.1  E8XDF4  77 aa hypothetical protein 0.036 ●○○○○ -0.57 -0.570098014414609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1026  NP_233410.1  Q9KKS4  385 aa hypothetical protein 0.021 ●○○○○ -0.57 -0.569553583686932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2164  AIK80769.1  295 aa protoheme IX farnesyltransferase 4.1e-5 ●○○○○ -0.57 -0.569407119978634
Escherichia coli M12  CO715_06130  ATI05332.1  342 aa autoinducer 2 ABC transporter permease LsrC 1.1e-8 ●○○○○ -0.57 -0.569095815642177
Porphyromonas gingivalis ATCC 33277  PGN_1372  WP_012458223.1  B2RKJ6  236 aa hemerythrin domain-containing protein 0.00051 ●○○○○ -0.57 -0.568761435044064
Porphyromonas gingivalis ATCC 33277  PGN_0445  WP_012457511.1  B2RHW9  368 aa efflux RND transporter periplasmic adaptor subunit 0.0026 ●○○○○ -0.57 -0.568761435044064
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3732  AIK82287.1  110 aa osmC-like family protein <1e-323 ●○○○○ -0.57 -0.568717704352544
Escherichia coli M12  CO715_19175  ATI07651.1  107 aa DUF1318 domain-containing protein 5.4e-12 ●○○○○ -0.57 -0.568052585570933
Porphyromonas gingivalis ATCC 33277  PGN_2064  WP_012458725.1  B2RMI7  265 aa M48 family peptidase <1e-323 ●○○○○ -0.57 -0.568020340769485
Escherichia coli M12  CO715_24445  ATI08581.1  814 aa acyl-CoA dehydrogenase 9.9e-19 ●○○○○ -0.57 -0.567843939556684
Escherichia coli M12  CO715_15895  ATI07061.1  475 aa DNA recombination protein RmuC 0.0011 ●○○○○ -0.57 -0.567635293542435
Porphyromonas gingivalis ATCC 33277  PGN_0228  WP_012457347.1  B2RHA2  444 aa phenylacetate--CoA ligase family protein <1e-323 ●○○○○ -0.57 -0.567202578507501
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4394  AIK82937.1  223 aa hypothetical protein 1.0e-10 ●○○○○ -0.57 -0.567165537747941
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1663  WP_001193265.1  E8XJY1  nifJ  1174 aa pyruvate:ferredoxin (flavodoxin) oxidoreductase 0.0047 ●○○○○ -0.57 -0.566799947359618
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1699  NP_231335.1  Q9KRE3  89 aa hypothetical protein 0.0046 ●○○○○ -0.57 -0.566553171162533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4222  AIK82767.1  341 aa putative membrane fusion protein of efflux pump 2.3e-9 ●○○○○ -0.57 -0.566165759482571
Porphyromonas gingivalis ATCC 33277  PGN_0444  WP_005875133.1  B2RHW8  455 aa TolC family protein 2.7e-6 ●○○○○ -0.57 -0.566155595378869
Escherichia coli M12  CO715_11325  ATI06242.1  347 aa NAD(P)-dependent alcohol dehydrogenase 1.2e-51 ●○○○○ -0.57 -0.565966125428444
Escherichia coli M12  CO715_16585  ATI07190.1  304 aa non-specific ribonucleoside hydrolase RihC 1.6e-38 ●○○○○ -0.57 -0.565548833399947
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2616  WP_000375791.1  E8XGK3  ratA  1865 aa outer membrane protein RatA 0.029 ●○○○○ -0.57 -0.56512807748652
Escherichia coli M12  CO715_17670  ATI07386.1  167 aa lytic transglycosylase 0.0069 ●○○○○ -0.56 -0.5649228953572
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4495  WP_000028075.1  E8X9V0  melB  476 aa melibiose:sodium transporter MelB 0.0075 ●○○○○ -0.56 -0.564868778971786
Porphyromonas gingivalis ATCC 33277  PGN_0929  WP_012457889.1  B2RJA3  633 aa ATP-binding protein 2.1e-11 ●○○○○ -0.56 -0.564070950114621
Porphyromonas gingivalis ATCC 33277  PGN_0929  WP_080504411.1  B2RJA3  69 aa KTSC domain-containing protein 2.1e-11 ●○○○○ -0.56 -0.564070950114621
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2365  AIK80962.1  129 aa glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein <1e-323 ●○○○○ -0.56 -0.563949817016008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3483  AIK82039.1  305 aa ABC transporter family protein <1e-323 ●○○○○ -0.56 -0.563812172973468
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3298  AIK81859.1  457 aa oxygen-independent coproporphyrinogen III oxidase <1e-323 ●○○○○ -0.56 -0.563705090050195
Escherichia coli M12  CO715_21360  ATI08049.1  518 aa phage resistance protein 0.025 ●○○○○ -0.56 -0.563462373257458
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4236  WP_000812819.1  E8XKC1  327 aa TRAP transporter substrate-binding protein 0.047 ●○○○○ -0.56 -0.563288712516686
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1014  WP_010989004.1  E8XDH7  105 aa hypothetical protein 0.038 ●○○○○ -0.56 -0.563138704823914
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3935  AIK82483.1  233 aa pirin family protein 2.4e-13 ●○○○○ -0.56 -0.562982461218512
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0989  NP_233373.1  Q9KKW1  444 aa hypothetical protein 5.4e-5 ●○○○○ -0.56 -0.561994956229028
Escherichia coli M12  CO715_06005  ATI05309.1  296 aa sensor domain-containing diguanylate cyclase 4.7e-15 ●○○○○ -0.56 -0.561793205143467
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4334  AIK82879.1  241 aa precorrin-3B C17-methyltransferase 5.0e-5 ●○○○○ -0.56 -0.561502616233186
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3338  WP_000833405.1  E8XBB3  yqib  140 aa DUF1249 family protein 0.05 ●○○○○ -0.56 -0.561237837411505
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4556  WP_001122537.1  E8XAN5  mutL  618 aa DNA mismatch repair endonuclease MutL 0.0051 ●○○○○ -0.56 -0.560727995508943
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3318  AIK81875.1  321 aa branched-chain amino acid transport system / permease component family protein 5.0e-14 ●○○○○ -0.56 -0.559320593626867
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2803  AIK81392.1  521 aa amidohydrolase family protein <1e-323 ●○○○○ -0.56 -0.559124810353981
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2606  NP_232234.2  Q9KNX4  kefB  600 aa glutathione-regulated potassium-efflux system protein KefB 1.5e-5 ●○○○○ -0.56 -0.558583118481719
Escherichia coli M12  CO715_01350  ATI04497.1  419 aa protease modulator HflK 4.2e-9 ●○○○○ -0.56 -0.558454868915485
Escherichia coli M12  CO715_09320  ATI05893.1  816 aa fimbrial biogenesis outer membrane usher protein 8.2e-119 ●○○○○ -0.56 -0.55762028485849
Escherichia coli M12  CO715_00490  ATI04344.1  417 aa valine--pyruvate transaminase 6.3e-6 ●○○○○ -0.56 -0.557411638844241
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1462  NP_231105.1  Q9KS08  127 aa RstB2 protein 2.6e-6 ●○○○○ -0.56 -0.557023692549627
Escherichia coli M12  CO715_14540  ATI06821.1  254 aa nickel import ATP-binding protein NikD 9.7e-27 ●○○○○ -0.56 -0.556994346815743
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1251  WP_001518864.1  E8XFH8  156 aa Hsp20 family protein 0.0065 ●○○○○ -0.56 -0.556831719958224
Escherichia coli M12  CO715_01340  ATI04495.1  65 aa DUF2065 domain-containing protein 0.0086 ●○○○○ -0.56 -0.556577054787246
Escherichia coli M12  CO715_10535  ATI06096.1  146 aa DUF2569 domain-containing protein 7.1e-13 ●○○○○ -0.56 -0.556159762758748
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0584  NP_232974.1  Q9KM05  222 aa glutathione S-transferase 0.0019 ●○○○○ -0.56 -0.555930517658083
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2111  NP_231742.1  Q9KQ90  175 aa hypothetical protein 6.8e-7 ●○○○○ -0.56 -0.555919670277131
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4024  AIK82571.1  223 aa hypothetical protein 5.4e-5 ●○○○○ -0.56 -0.555618676631425
Escherichia coli M12  CO715_05735  ATI05272.1  253 aa abortive phage resistance protein 5.2e-16 ●○○○○ -0.56 -0.555325178701752
Escherichia coli M12  CO715_20425  ATI07881.1  315 aa transcriptional regulator 6.3e-9 ●○○○○ -0.56 -0.555116532687503
Escherichia coli M12  CO715_14685  ATI06848.1  732 aa zinc/cadmium/mercury/lead-transporting ATPase 1.4e-61 ●○○○○ -0.55 -0.554699240659006
Escherichia coli M12  CO715_09330  ATI05895.1  353 aa hypothetical protein 7.7e-12 ●○○○○ -0.55 -0.554699240659006
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4254  WP_000113090.1  E8XKD9  lsrk  530 aa autoinducer-2 kinase 0.0068 ●○○○○ -0.55 -0.5546834842482
Acinetobacter baumannii ATCC 17978  A1S_2132  ABO12559.2  906 aa putative outer membrane protein 0.0044 ●○○○○ -0.55 -0.554466980614707
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1542  WP_001189401.1  E8XIX8  295 aa ATP/GTP-binding protein 0.0068 ●○○○○ -0.55 -0.554208993137422
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4755  AIK83290.1  332 aa sodium Bile acid symporter family protein 8.9e-8 ●○○○○ -0.55 -0.552973300827992
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3484  AIK82040.1  364 aa ABC-2 type transporter family protein <1e-323 ●○○○○ -0.55 -0.552934297249716
Acinetobacter baumannii ATCC 17978  A1S_1794  ABO12221.1  391 aa hypothetical protein 0.0023 ●○○○○ -0.55 -0.551903368094386
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4478  WP_000083232.1  E8X9T3  nrfG  206 aa heme lyase NrfEFG subunit NrfG 0.022 ●○○○○ -0.55 -0.551851124614772
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1170  AIK79793.1  249 aa DNA-binding transcriptional regulator 2.7e-5 ●○○○○ -0.55 -0.551785271298602
Escherichia coli M12  CO715_12020  ATI06370.1  274 aa hypothetical protein 2.7e-36 ●○○○○ -0.55 -0.551360904431024
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4786  WP_000093829.1  E8XDB4  nadR  410 aa multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.0057 ●○○○○ -0.55 -0.55014554913893
Escherichia coli M12  CO715_03460  ATI04876.1  392 aa arabinose transporter 5.8e-6 ●○○○○ -0.55 -0.550109028345531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3808  AIK82358.1  293 aa ribosomal protein L11 methyltransferase 1.4e-6 ●○○○○ -0.55 -0.549235617126958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4082  AIK82628.1  352 aa A/G-specific adenine glycosylase <1e-323 ●○○○○ -0.55 -0.548782286256717
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1982  AIK80588.1  82 aa hypothetical protein 8.7e-6 ●○○○○ -0.55 -0.548446574350473
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0043  NP_229702.1  Q9KVU6  458 aa potassium transporter peripheral membrane protein 0.00067 ●○○○○ -0.55 -0.548004958517149
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1651  AIK80271.1  270 aa HAD hydrolase, IIB family protein <1e-323 ●○○○○ -0.55 -0.547764103970216
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3132  WP_014343890.1  E8X8S1  295 aa EamA family transporter RarD 0.022 ●○○○○ -0.55 -0.547542585878518
Porphyromonas gingivalis ATCC 33277  PGN_0856  WP_023846950.1  B2RJ30  381 aa A/G-specific adenine glycosylase 7.2e-11 ●○○○○ -0.55 -0.547514957911125
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3947  AIK82495.1  433 aa exuT hexuronate MFS transporter <1e-323 ●○○○○ -0.55 -0.54737590414674
Escherichia coli M12  CO715_10820  ATI06146.1  406 aa cysteine desulfurase 6.0e-6 ●○○○○ -0.55 -0.547187984146047
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1557  AIK80177.1  277 aa dimethyl sulfoxide reductase, chain C 0.0072 ●○○○○ -0.55 -0.546979687003353
Escherichia coli M12  CO715_11505  ATI06276.1  636 aa ATP-dependent DNA helicase 1.8e-6 ●○○○○ -0.55 -0.546353400089051
Escherichia coli M12  CO715_06030  ATI05314.1  127 aa MDR efflux pump AcrAB transcriptional activator MarA 0.021 ●○○○○ -0.55 -0.546353400089051
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4297  AIK82842.1  614 aa exodeoxyribonuclease V, alpha subunit 0.0017 ●○○○○ -0.55 -0.546267250324507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3228  AIK81789.1  257 aa acetylglutamate kinase 0.0032 ●○○○○ -0.55 -0.546176668934696
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1355  WP_000117497.1  E8XGF7  ydiD  546 aa medium-chain fatty-acid--CoA ligase 0.022 ●○○○○ -0.55 -0.545460352473139
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0842  NP_230490.1  H9L4P4  157 aa hypothetical protein 1.6e-5 ●○○○○ -0.54 -0.54412856295645
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4577  AIK83115.1  356 aa 3-deoxy-7-phosphoheptulonate synthase 2.4e-13 ●○○○○ -0.54 -0.543988931340732
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3087  AIK81669.1  443 aa response regulator 1.1e-16 ●○○○○ -0.54 -0.543924648033098
Escherichia coli M12  CO715_08540  ATI05757.1  561 aa transporter 3.0e-7 ●○○○○ -0.54 -0.543849647918065
Escherichia coli M12  CO715_21280  ATI08036.1  836 aa outer membrane autotransporter barrel domain-containing protein 2.0e-7 ●○○○○ -0.54 -0.543641001903816
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3439  AIK81995.1  284 aa eamA-like transporter family protein 1.5e-7 ●○○○○ -0.54 -0.543368289474342
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1922  WP_001184028.1  E8X9F7  yeba  439 aa murein DD-endopeptidase MepM 0.0081 ●○○○○ -0.54 -0.542460173171275
Escherichia coli M12  CO715_01840  ATI04583.1  437 aa glutamate/aspartate:proton symporter GltP 4.8e-7 ●○○○○ -0.54 -0.542180479804074
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1895  AIK80501.1  334 aa branched-chain amino acid transport system / permease component family protein 3.3e-7 ●○○○○ -0.54 -0.541939573576496
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0557  NP_232947.1  Q9KM32  469 aa diguanylate cyclase 0.029 ●○○○○ -0.54 -0.541899091358764
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4252  AIK82797.1  153 aa bacterial Transmembrane Pair family protein 3.8e-14 ●○○○○ -0.54 -0.541754880198113
Retrieved entries 5,301–5,400 out of 36,363 total in 8.7 ms (Link to these results)