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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4154  AIK82700.1  103 aa hypothetical protein 1.5e-8 ●○○○○ -0.44 -0.441829237816815
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3591  AIK82146.1  428 aa dctA dicarboxylate transporter <1e-323 ●○○○○ -0.44 -0.441018509257617
Escherichia coli M12  CO715_20815  ATI07950.1  402 aa multidrug resistance protein MdtH 0.009 ●○○○○ -0.44 -0.440987162893376
Escherichia coli M12  CO715_07825  ATI05627.1  265 aa DNA-binding protein 6.7e-5 ●○○○○ -0.44 -0.440569870864879
Porphyromonas gingivalis ATCC 33277  PGN_0903  WP_012457866.1  B2RJ77  fimR  227 aa response regulator transcription factor <1e-323 ●○○○○ -0.44 -0.439871321115254
Escherichia coli M12  CO715_05195  ATI05179.1  610 aa excinuclease ABC subunit C 0.00011 ●○○○○ -0.44 -0.439735286807883
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3161  AIK81733.1  297 aa eamA-like transporter family protein <1e-323 ●○○○○ -0.44 -0.439518733818806
Porphyromonas gingivalis ATCC 33277  PGN_0271  WP_012457383.1  B2RHE5  689 aa M13 family peptidase <1e-323 ●○○○○ -0.44 -0.439444439694199
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0450  NP_230104.2  Q9KUR5  375 aa membrane-bound lytic murein transglycosylase C 4.2e-5 ●○○○○ -0.44 -0.439300932231477
Acinetobacter baumannii ATCC 17978  A1S_1006  ABO11438.1  149 aa putative transcriptional regulator 0.0031 ●○○○○ -0.44 -0.438846159340544
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4548  AIK83086.1  316 aa agmatinase 6.5e-6 ●○○○○ -0.44 -0.438835818012506
Escherichia coli M12  CO715_22730  ATI08293.1  516 aa YjjI family glycine radical enzyme 6.9e-7 ●○○○○ -0.44 -0.43848341072239
Escherichia coli M12  CO715_04465  ATI05056.1  238 aa YebC/PmpR family DNA-binding transcriptional regulator 6.6e-8 ●○○○○ -0.44 -0.438066118693892
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1085  NP_230730.1  Q9KT20  434 aa sensor histidine kinase 1.2e-5 ●○○○○ -0.44 -0.43801137357929
Acinetobacter baumannii ATCC 17978  A1S_0505  ABO10958.2  381 aa hypothetical protein 0.0025 ●○○○○ -0.44 -0.437675670464813
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0070  NP_229729.1  Q9KVR9  94 aa hypothetical protein 3.8e-7 ●○○○○ -0.44 -0.437010338622572
Escherichia coli M12  CO715_07095  ATI05502.1  261 aa phage recombination protein Bet 1.4e-16 ●○○○○ -0.44 -0.43660559659415
Escherichia coli M12  CO715_05845  ATI05287.1  223 aa tail assembly protein 0.041 ●○○○○ -0.44 -0.43660559659415
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2681  AIK81275.1  470 aa putative regulator 5.2e-11 ●○○○○ -0.44 -0.436018111549388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2292  AIK80896.1  881 aa bacterial regulatory, luxR family protein <1e-323 ●○○○○ -0.44 -0.435656554593156
Porphyromonas gingivalis ATCC 33277  PGN_1246  WP_012458136.1  B2RK70  1383 aa hypothetical protein <1e-323 ●○○○○ -0.44 -0.435056197214053
Porphyromonas gingivalis ATCC 33277  PGN_1962  WP_012458645.1  B2RM85  352 aa hypothetical protein 8.9e-5 ●○○○○ -0.44 -0.435056197214053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3096  AIK81677.1  257 aa NUDIX domain protein 2.3e-7 ●○○○○ -0.44 -0.435043926352728
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0148  NP_229806.1  Q9KVJ5  ftsE  233 aa cell division ATP-binding protein FtsE 0.00016 ●○○○○ -0.44 -0.435033255733634
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4208  AIK82753.1  267 aa carboxymuconolactone decarboxylase family protein 6.3e-5 ●○○○○ -0.43 -0.434800560601145
Escherichia coli M12  CO715_01605  ATI04541.1  90 aa N-acetyltransferase 0.007 ●○○○○ -0.43 -0.434101844423164
Acinetobacter baumannii ATCC 17978  A1S_1007  ABO11439.1  108 aa putative transcriptional regulator 0.03 ●○○○○ -0.43 -0.433669712234759
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3269  AIK81830.1  335 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.43 -0.433508063900114
Escherichia coli M12  CO715_14405  ATI06794.1  27 aa Damage inducible protein 0.0026 ●○○○○ -0.43 -0.433475906380417
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2896  AIK81485.1  619 aa mutL 1.0e-10 ●○○○○ -0.43 -0.433297899649428
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3235  WP_001540881.1  E8XAD7  yqgB  54 aa hypothetical protein 0.022 ●○○○○ -0.43 -0.432353974125653
Porphyromonas gingivalis ATCC 33277  PGN_0063  WP_012457209.1  B2RGT7  traJ  358 aa conjugative transposon protein TraJ <1e-323 ●○○○○ -0.43 -0.432070995525812
Escherichia coli M12  CO715_12475  ATI06449.1  495 aa altronate dehydratase 1.1e-17 ●○○○○ -0.43 -0.432015384280675
Escherichia coli M12  CO715_11910  ATI06350.1  294 aa NAD(P)-dependent oxidoreductase 3.4e-8 ●○○○○ -0.43 -0.432015384280675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0610  NP_230259.1  Q9KUB3  343 aa iron(III) ABC transporter ATP-binding protein 0.00014 ●○○○○ -0.43 -0.43200167290749
Acinetobacter baumannii ATCC 17978  A1S_1880  ABO12307.2  809 aa pyrroloquinoline-quinone QuiA 0.003 ●○○○○ -0.43 -0.431981807827154
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2160  NP_231791.1  Q9KQ44  155 aa thioredoxin-dependent thiol peroxidase 0.0034 ●○○○○ -0.43 -0.431607718646599
Acinetobacter baumannii ATCC 17978  A1S_1924  ABO12351.2  528 aa cytochrome d terminal oxidase polypeptide subunit I 0.0038 ●○○○○ -0.43 -0.431560246387428
Acinetobacter baumannii ATCC 17978  A1S_0738  ABO11178.2  163 aa putative flavoprotein oxidoreductase 0.005 ●○○○○ -0.43 -0.431497338790515
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3625  AIK82180.1  661 aa fused UDP-L-Ara4N formyltransferase and UDP-GlcAC-4''-decarboxylase <1e-323 ●○○○○ -0.43 -0.431127366636628
Acinetobacter baumannii ATCC 17978  A1S_1194  ABO11624.2  259 aa hypothetical protein 0.028 ●○○○○ -0.43 -0.430393269254719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1820  AIK80433.1  546 aa phosphoglucomutase, alpha-D-glucose phosphate-specific 6.3e-10 ●○○○○ -0.43 -0.429935257650064
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0914  WP_000756589.1  E8XCN5  artI  243 aa arginine ABC transporter substrate-binding protein 0.025 ●○○○○ -0.43 -0.429834668312505
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3699  AIK82254.1  292 aa molecular chaperone Hsp33 0.0034 ●○○○○ -0.43 -0.429354809387934
Escherichia coli M12  CO715_21570  ATI08888.1  315 aa tRNA dihydrouridine(16) synthase DusC 0.001 ●○○○○ -0.43 -0.42930298609544
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2337  AIK80941.1  222 aa methyltransferase domain protein <1e-323 ●○○○○ -0.43 -0.429264507086761
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0698  NP_230347.1  Q9KU31  555 aa ABC transporter ATP-binding protein 0.00058 ●○○○○ -0.43 -0.42885687696082
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2018  NP_231652.2  Q9KQI0  pabC  267 aa 4-amino-4-deoxychorismate lyase 2.7e-6 ●○○○○ -0.43 -0.42863132519104
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0993  NP_230639.1  Q9KTB0  404 aa N-acetylglucosamine repressor 0.011 ●○○○○ -0.43 -0.428315287571755
Escherichia coli M12  CO715_12490  ATI06450.1  258 aa transcriptional regulator ExuR 2.4e-6 ●○○○○ -0.43 -0.428051110009947
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0848  NP_230495.1  P52116  smpB  161 aa SsrA-binding protein 0.00015 ●○○○○ -0.43 -0.427940493939698
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2957  WP_001279499.1  E8XK63  yqaA  141 aa DedA family protein 0.038 ●○○○○ -0.43 -0.426604703151582
Escherichia coli M12  CO715_18790  ATI07582.1  121 aa hypothetical protein 7.2e-30 ●○○○○ -0.43 -0.426381941895956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4064  AIK82611.1  303 aa bacterial regulatory helix-turn-helix, lysR family protein 7.7e-12 ●○○○○ -0.43 -0.426335116566976
Escherichia coli M12  CO715_14760  ATI06863.1  425 aa branched-chain amino acid ABC transporter permease 0.0058 ●○○○○ -0.43 -0.425964649867458
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0929  WP_000125877.1  E8XCQ0  ybjZ  648 aa macrolide ABC transporter ATP-binding protein/permease MacB 0.024 ●○○○○ -0.43 -0.425709975816336
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3603  AIK82158.1  207 aa glutathione S-transferase, C-terminal domain protein 2.0e-6 ●○○○○ -0.43 -0.425462651115662
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4283  AIK82828.1  237 aa integral membrane TerC family protein <1e-323 ●○○○○ -0.43 -0.425107819725632
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3654  AIK82209.1  233 aa livF 2.0e-8 ●○○○○ -0.42 -0.42399936237634
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1250  NP_230895.1  Q9KSK6  299 aa hypothetical protein 0.00084 ●○○○○ -0.42 -0.423261043914816
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2137  AIK80742.1  287 aa acyl-CoA thioesterase II 0.0034 ●○○○○ -0.42 -0.423079341557786
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0881  NP_230528.1  Q9KTM1  149 aa hypothetical protein 0.00019 ●○○○○ -0.42 -0.422948204961695
Acinetobacter baumannii ATCC 17978  A1S_2902  ABO13308.2  342 aa hypothetical protein 0.0053 ●○○○○ -0.42 -0.422890145815218
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2669  AIK81263.1  271 aa cupin domain protein <1e-323 ●○○○○ -0.42 -0.422684810998672
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2185  NP_231816.2  Q9KQ20  ychF  363 aa GTP-dependent nucleic acid-binding protein EngD 3.5e-6 ●○○○○ -0.42 -0.422651355013309
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3705  WP_000098543.1  E8XEP1  glgB  728 aa 1,4-alpha-glucan branching enzyme 0.04 ●○○○○ -0.42 -0.422234074108487
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2345  NP_231975.1  Q9KPM2  328 aa phosphoserine phosphatase 9.3e-5 ●○○○○ -0.42 -0.422025284375379
Escherichia coli M12  CO715_19305  ATI07674.1  537 aa peptide ABC transporter substrate-binding protein 7.0e-140 ●○○○○ -0.42 -0.421791729582481
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4091  AIK82637.1  96 aa hypothetical protein 0.00026 ●○○○○ -0.42 -0.421570276902162
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0714  NP_233101.1  Q9KLM9  118 aa diacylglycerol kinase 0.021 ●○○○○ -0.42 -0.421386989156429
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0288  NP_229943.2  Q9KV69  598 aa phosphogluconate dehydratase 0.00013 ●○○○○ -0.42 -0.421020985656027
Acinetobacter baumannii ATCC 17978  A1S_2173  ABO12600.1  A3M6Q6  rplI  148 aa 50S ribosomal protein L9 0.0044 ●○○○○ -0.42 -0.418872858923971
Porphyromonas gingivalis ATCC 33277  PGN_1348  WP_012458207.1  B2RKH2  246 aa DUF2807 domain-containing protein 1.9e-15 ●○○○○ -0.42 -0.418182224801735
Escherichia coli M12  CO715_15465  ATI06987.1  502 aa glycerol kinase 6.0e-6 ●○○○○ -0.42 -0.418036101326002
Escherichia coli M12  CO715_16000  ATI07081.1  243 aa fimbrial chaperone 4.4e-5 ●○○○○ -0.42 -0.417827455311753
Porphyromonas gingivalis ATCC 33277  PGN_1401  WP_012458244.1  B2RKM5  543 aa L-glutamate gamma-semialdehyde dehydrogenase <1e-323 ●○○○○ -0.42 -0.416968253479139
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3560  AIK82117.1  146 aa acetyltransferase family protein 9.2e-6 ●○○○○ -0.42 -0.416822689201977
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2272  WP_000553526.1  E8XDM0  cdd  294 aa cytidine deaminase 0.029 ●○○○○ -0.42 -0.416613185523517
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4445  AIK82988.1  466 aa 6-phospho-beta-glucosidase gmuD <1e-323 ●○○○○ -0.42 -0.416514037145805
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0201  NP_229858.2  Q9KVE5  261 aa iron(III) ABC transporter ATP-binding protein 0.00011 ●○○○○ -0.42 -0.416406202626513
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0234  NP_229891.1  Q9KVB2  262 aa hypothetical protein 2.6e-6 ●○○○○ -0.42 -0.416286492742913
Escherichia coli M12  CO715_10930  ATI06166.1  429 aa FAD-dependent oxidoreductase 1.5e-6 ●○○○○ -0.42 -0.416158287197762
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1392  NP_231036.1  Q9KS67  cry2  504 aa deoxyribodipyrimidine photolyase 0.00062 ●○○○○ -0.42 -0.415387723538415
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0518  NP_230169.1  587 aa DNA primase 0.0014 ●○○○○ -0.42 -0.415291568030399
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2843  AIK81432.1  301 aa ytfQ <1e-323 ●○○○○ -0.41 -0.41480785429099
Escherichia coli M12  CO715_23945  ATI08492.1  532 aa transcriptional regulator 2.5e-6 ●○○○○ -0.41 -0.414489119083771
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1507  AIK80127.1  546 aa mce related family protein 2.9e-8 ●○○○○ -0.41 -0.41353837394675
Acinetobacter baumannii ATCC 17978  A1S_2102  ABO12529.2  503 aa aldehyde dehydrogenase 1 0.0053 ●○○○○ -0.41 -0.413337723372798
Escherichia coli M12  CO715_11105  ATI06201.1  450 aa 6-phospho-beta-glucosidase <1e-323 ●○○○○ -0.41 -0.413237242998278
Escherichia coli M12  CO715_06375  ATI05377.1  137 aa DNA-binding protein H-NS 6.9e-38 ●○○○○ -0.41 -0.413237242998278
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2675  NP_232303.1  Q9KNQ6  hslV  185 aa ATP-dependent protease peptidase subunit 9.6e-6 ●○○○○ -0.41 -0.412007757199287
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0691  NP_233079.1  Q9KLQ1  246 aa acetoacetyl-CoA reductase 0.023 ●○○○○ -0.41 -0.412004073694529
Escherichia coli M12  CO715_13685  ATI06665.1  197 aa TetR/AcrR family transcriptional regulator 0.00084 ●○○○○ -0.41 -0.411776720898536
Escherichia coli M12  CO715_05235  ATI05184.1  165 aa non-heme ferritin 3.0e-93 ●○○○○ -0.41 -0.411359428870038
Escherichia coli M12  CO715_04355  ATI05045.1  441 aa DNA-binding response regulator 5.4e-37 ●○○○○ -0.41 -0.410733490827292
Escherichia coli M12  CO715_12990  ATI08804.1  183 aa outer membrane lipid asymmetry maintenance protein MlaD 4.6e-5 ●○○○○ -0.41 -0.410316198798794
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3601  AIK82156.1  550 aa trehalase family protein <1e-323 ●○○○○ -0.41 -0.409496078368645
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2515  AIK81112.1  785 aa DNA polymerase II 7.9e-14 ●○○○○ -0.41 -0.409287779815872
Acinetobacter baumannii ATCC 17978  A1S_2301  ABO12724.2  229 aa Amino acid ABC transporter permease protein 0.018 ●○○○○ -0.41 -0.409255222970651
Porphyromonas gingivalis ATCC 33277  PGN_0073  WP_012457218.1  B2RGU7  traA  260 aa ParA family protein <1e-323 ●○○○○ -0.41 -0.409114779720747
Retrieved entries 5,701–5,800 out of 36,363 total in 8.4 ms (Link to these results)