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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_05385  ATI05210.1  188 aa VOC family protein 0.0013 ●○○○○ -0.41 -0.409064322713301
Porphyromonas gingivalis ATCC 33277  PGN_1523  WP_012458342.1  B2RKZ7  268 aa polysaccharide export outer membrane protein 3.9e-14 ●○○○○ -0.41 -0.408696522909852
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0821  NP_233207.1  Q9KLC5  68 aa hypothetical protein 7.9e-5 ●○○○○ -0.41 -0.408117204697819
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4663  AIK83198.1  463 aa exodeoxyribonuclease VII, large subunit 0.0019 ●○○○○ -0.41 -0.408081998703176
Porphyromonas gingivalis ATCC 33277  PGN_0093  WP_012457235.1  B2RGW7  121 aa hypothetical protein 1.4e-6 ●○○○○ -0.41 -0.40779217173706
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2866  AIK81455.1  149 aa ribosomal protein L9 <1e-323 ●○○○○ -0.41 -0.407437280694793
Escherichia coli M12  CO715_11060  ATI06192.1  286 aa fructosamine kinase family protein 8.2e-71 ●○○○○ -0.41 -0.40739515459931
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1602  WP_001517827.1  E8XJ37  yncB  345 aa NADP-dependent oxidoreductase 0.029 ●○○○○ -0.41 -0.407008231234004
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2773  AIK81362.1  357 aa ugpC 1.6e-10 ●○○○○ -0.41 -0.406784569153659
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4422  AIK82965.1  853 aa DNA mismatch repair protein MutS <1e-323 ●○○○○ -0.41 -0.406523944735982
Porphyromonas gingivalis ATCC 33277  PGN_0087  WP_012457231.1  B2RGW1  636 aa hypothetical protein 2.7e-12 ●○○○○ -0.41 -0.406115767462127
Escherichia coli M12  CO715_00025  ATI04260.1  284 aa alpha/beta hydrolase 1.0e-10 ●○○○○ -0.41 -0.405934632499568
Acinetobacter baumannii ATCC 17978  A1S_2694  ABO13107.2  574 aa Mur ligase middle region 0.0086 ●○○○○ -0.41 -0.405676644739843
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1109  NP_233488.1  Q9KKJ6  236 aa hypothetical protein 8.4e-5 ●○○○○ -0.41 -0.405624497066095
Acinetobacter baumannii ATCC 17978  A1S_1579  ABO12006.2  350 aa putative ATPase 0.0046 ●○○○○ -0.41 -0.405395705638247
Escherichia coli M12  CO715_13845  ATI06694.1  184 aa YtfJ family protein 7.5e-13 ●○○○○ -0.41 -0.405308694456821
Escherichia coli M12  CO715_19910  ATI07783.1  590 aa multidrug ABC transporter permease/ATP-binding protein 1.8e-9 ●○○○○ -0.4 -0.404891402428323
Escherichia coli M12  CO715_05665  ATI05258.1  291 aa nucleic acid-binding protein 7.9e-24 ●○○○○ -0.4 -0.404682756414075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3208  AIK81776.1  521 aa acetolactate synthase, large subunit, biosynthetic type <1e-323 ●○○○○ -0.4 -0.404641264783037
Acinetobacter baumannii ATCC 17978  A1S_1042  ABO11474.1  83 aa hypothetical protein 0.0054 ●○○○○ -0.4 -0.40450264651919
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0420  NP_232814.2  Q9KME1  104 aa hypothetical protein 0.012 ●○○○○ -0.4 -0.404309742273283
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0287  NP_229942.1  Q9KV70  171 aa thermoresistant gluconokinase 0.00015 ●○○○○ -0.4 -0.403871028148014
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1275  NP_230920.1  Q9KSI1  427 aa hypothetical protein 0.0035 ●○○○○ -0.4 -0.40348864416751
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2057  AIK80663.1  434 aa citrate (Si)-synthase <1e-323 ●○○○○ -0.4 -0.403487044960599
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3689  WP_001232871.1  E8XEM5  rtcR  527 aa sigma 54-dependent transcriptional regulator 0.045 ●○○○○ -0.4 -0.403000779748882
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4007  AIK82554.1  54 aa short-chain dehydrogenase/reductase family oxidoreductase 0.00022 ●○○○○ -0.4 -0.402370008390647
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4511  WP_001576552.1  E8X9W6  73 aa hypothetical protein 0.033 ●○○○○ -0.4 -0.401986934599183
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1110  WP_000749201.1  E8XE74  agp  413 aa bifunctional glucose-1-phosphatase/inositol phosphatase 0.032 ●○○○○ -0.4 -0.401970913220681
Porphyromonas gingivalis ATCC 33277  PGN_1670  WP_005874170.1  B2RLE4  192 aa peptidoglycan domain protein <1e-323 ●○○○○ -0.4 -0.401212112774134
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2055  WP_000088182.1  E8XB43  577 aa terminase large subunit 0.041 ●○○○○ -0.4 -0.400939264404353
Escherichia coli M12  CO715_04030  ATI04982.1  408 aa phosphopentomutase 1.6e-21 ●○○○○ -0.4 -0.400927128157595
Escherichia coli M12  CO715_18615  ATI07552.1  102 aa PTS sorbitol transporter 3.9e-8 ●○○○○ -0.4 -0.4000925441006
Porphyromonas gingivalis ATCC 33277  PGN_0229  WP_012457348.1  B2RHA3  161 aa histidinol phosphate phosphatase <1e-323 ●○○○○ -0.4 -0.399961577241193
Escherichia coli M12  CO715_10960  ATI06172.1  348 aa phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive 0.013 ●○○○○ -0.4 -0.399675252072102
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2973  AIK81558.1  378 aa phosphonate metabolism protein PhnM <1e-323 ●○○○○ -0.4 -0.399637533145316
Porphyromonas gingivalis ATCC 33277  PGN_1415  WP_012458253.1  B2RKN9  172 aa histidinol phosphate phosphatase 0.035 ●○○○○ -0.4 -0.399509178578744
Acinetobacter baumannii ATCC 17978  A1S_1427  ABO11855.2  312 aa malonate decarboxylase epsilon subunit 0.042 ●○○○○ -0.4 -0.399288934797278
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3007  AIK81591.1  109 aa bacterial regulatory helix-turn-helix, AraC family protein 5.6e-11 ●○○○○ -0.4 -0.398050046692134
Escherichia coli M12  CO715_23170  ATI08369.1  437 aa permease 1.4e-43 ●○○○○ -0.4 -0.398006083958111
Escherichia coli M12  CO715_20390  ATI07875.1  403 aa 3-(3-hydroxy-phenyl)propionate transporter MhpT 3.7e-36 ●○○○○ -0.4 -0.397588791929613
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4463  AIK83006.1  480 aa PTS system, maltose and glucose-specific subfamily, IIC component domain protein <1e-323 ●○○○○ -0.4 -0.396806923304876
Escherichia coli CFT073  c1818  AAN80282.1  Q8FHP6  ttcA  311 aa Hypothetical protein ydaO 0.045 ●○○○○ -0.4 -0.396788504792042
Escherichia coli M12  CO715_13115  ATI06564.1  291 aa N-acetylmannosamine kinase 0.002 ●○○○○ -0.4 -0.396754207872618
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1212  WP_000482967.1  E8XEY3  ycfS  321 aa LysM peptidoglycan-binding domain-containing protein 0.033 ●○○○○ -0.4 -0.396603398288777
Escherichia coli M12  CO715_10450  ATI06080.1  467 aa class II fumarate hydratase 3.7e-6 ●○○○○ -0.4 -0.39633691584412
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3657  AIK82212.1  438 aa ugpB <1e-323 ●○○○○ -0.4 -0.396133483457946
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2876  AIK81465.1  85 aa ulaB 1.1e-14 ●○○○○ -0.4 -0.396127180573725
Acinetobacter baumannii ATCC 17978  A1S_0031  ABO10526.2  451 aa N-alpha-acetylglutamate synthase 0.0061 ●○○○○ -0.4 -0.395833539845807
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4683  AIK83217.1  510 aa ppx <1e-323 ●○○○○ -0.4 -0.395506905003008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1914  AIK80520.1  500 aa ABC transporter family protein 3.4e-10 ●○○○○ -0.4 -0.395298942848197
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0630  NP_230279.1  Q9KU93  433 aa hypothetical protein 0.0042 ●○○○○ -0.4 -0.39512957001311
Escherichia coli M12  CO715_20260  ATI07850.1  471 aa alkaline phosphatase 1.9e-79 ●○○○○ -0.4 -0.395085039758627
Porphyromonas gingivalis ATCC 33277  PGN_0674  WP_012457688.1  B2RIJ8  275 aa TonB family protein <1e-323 ●○○○○ -0.39 -0.394450556949852
Escherichia coli CFT073  c2679  AAN81135.1  A0A0H2VAB5  yeiT  412 aa Hypothetical oxidoreductase yeiT 0.0057 ●○○○○ -0.39 -0.394271478254985
Escherichia coli M12  CO715_08640  ATI05775.1  623 aa glutathione ABC transporter ATP-binding protein GsiA 8.7e-29 ●○○○○ -0.39 -0.394041809687383
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1312  NP_230956.2  Q9KSE5  bsrV  407 aa alanine racemase 8.3e-5 ●○○○○ -0.39 -0.393874952428086
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1039  NP_230684.1  Q9KT66  703 aa asmA protein 4.7e-5 ●○○○○ -0.39 -0.393235269124663
Porphyromonas gingivalis ATCC 33277  PGN_1338  WP_012458198.1  B2RKG2  908 aa pyruvate, phosphate dikinase <1e-323 ●○○○○ -0.39 -0.392485015196339
Escherichia coli M12  CO715_02085  ATI04627.1  371 aa maltose/maltodextrin import ATP-binding protein MalK 0.037 ●○○○○ -0.39 -0.392372641573392
Acinetobacter baumannii ATCC 17978  A1S_1635  ABO12062.2  215 aa putative membrane protein 0.031 ●○○○○ -0.39 -0.391851597535999
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2727  NP_232354.1  P45776  epsJ  221 aa general secretion pathway protein J 0.0056 ●○○○○ -0.39 -0.391746901295594
Escherichia coli M12  CO715_17285  ATI07317.1  301 aa hypothetical protein 2.6e-10 ●○○○○ -0.39 -0.391746703530645
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0346  NP_230000.1  Q9KV12  miaA  315 aa tRNA delta(2)-isopentenylpyrophosphate transferase 1.2e-5 ●○○○○ -0.39 -0.391700750376505
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2512  NP_232141.1  Q9KP64  129 aa hypothetical protein 1.2e-5 ●○○○○ -0.39 -0.39151671206655
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0884  NP_230531.1  Q9KTL8  207 aa acetyltransferase-like protein 3.8e-5 ●○○○○ -0.39 -0.391419942704387
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2992  AIK81577.1  551 aa cation/acetate symporter ActP <1e-323 ●○○○○ -0.39 -0.391400123569286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2309  AIK80913.1  422 aa L-2-hydroxyglutarate oxidase 0.048 ●○○○○ -0.39 -0.39136291816892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2963  AIK81548.1  500 aa proP proline/betaine MFS transporter <1e-323 ●○○○○ -0.39 -0.391357647116554
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1562  NP_231202.1  Q9KRS4  390 aa beta-lactamase-like protein 6.7e-5 ●○○○○ -0.39 -0.391304487685683
Acinetobacter baumannii ATCC 17978  A1S_1370  ABO11798.1  551 aa Oxidoreductase 0.036 ●○○○○ -0.39 -0.391065604784154
Escherichia coli M12  CO715_24600  ATI08609.1  732 aa xanthine dehydrogenase 7.9e-118 ●○○○○ -0.39 -0.390286181430903
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2642  NP_232270.1  Q9KNT8  argG  404 aa argininosuccinate synthase 0.0074 ●○○○○ -0.39 -0.390214723875477
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0033  NP_232434.1  Q9KND2  624 aa hypothetical protein 0.045 ●○○○○ -0.39 -0.389894208838424
Escherichia coli M12  CO715_11790  ATI06327.1  193 aa modulator of drug activity B 0.0084 ●○○○○ -0.39 -0.389451597373908
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3580  AIK82135.1  327 aa endoglucanase <1e-323 ●○○○○ -0.39 -0.389415860703502
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2191  WP_000699632.1  E8XCU4  wcaI  407 aa colanic acid biosynthesis glycosyltransferase WcaI 0.037 ●○○○○ -0.39 -0.388852396000336
Escherichia coli M12  CO715_19890  ATI07779.1  286 aa acyl-CoA thioesterase II 9.0e-22 ●○○○○ -0.39 -0.388408367302663
Escherichia coli M12  CO715_09735  ATI05964.1  317 aa LysR family transcriptional regulator 2.8e-8 ●○○○○ -0.39 -0.388408367302663
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5141  AIK83664.1  300 aa putative L,D-transpeptidase ErfK/SrfK 0.014 ●○○○○ -0.39 -0.388046705900154
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0381  WP_000848026.1  E8XJR5  dedD  91 aa DUF1471 domain-containing protein 0.04 ●○○○○ -0.39 -0.387165009003331
Escherichia coli M12  CO715_10395  ATI06071.1  344 aa pheromone autoinducer 2 transporter 9.2e-10 ●○○○○ -0.39 -0.386947845202921
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1993  AIK80599.1  347 aa hypothetical protein 4.5e-5 ●○○○○ -0.39 -0.386857831339825
Porphyromonas gingivalis ATCC 33277  PGN_1815  WP_012458553.1  B2RLT9  204 aa sulfurtransferase-like selenium metabolism protein YedF 0.00011 ●○○○○ -0.39 -0.386831802940921
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0027  NP_229686.1  Q9KVW1  ilvA  510 aa threonine dehydratase 0.00019 ●○○○○ -0.39 -0.386632316225572
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0083  NP_232484.1  Q9KN82  403 aa multidrug resistance protein D 1.1e-5 ●○○○○ -0.39 -0.386317070162867
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0909  NP_233294.1  Q9KL39  455 aa coproporphyrinogen III oxidase 2.0e-5 ●○○○○ -0.39 -0.38579959724147
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4324  AIK82869.1  269 aa glpF - glycerol MIP channel 4.2e-5 ●○○○○ -0.39 -0.38557300434637
Acinetobacter baumannii ATCC 17978  A1S_1037  ABO11469.2  186 aa hypothetical protein 0.044 ●○○○○ -0.39 -0.385498723780954
Escherichia coli M12  CO715_03775  ATI04936.1  550 aa 4-amino-4-deoxy-L-arabinose lipid A transferase 7.4e-46 ●○○○○ -0.39 -0.38527867708893
Escherichia coli M12  CO715_11125  ATI06204.1  106 aa PTS sugar transporter subunit IIB 7.5e-5 ●○○○○ -0.38 -0.384652739046184
Escherichia coli M12  CO715_15230  ATI06946.1  413 aa AGE family epimerase/isomerase 0.0011 ●○○○○ -0.38 -0.384444093031935
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2608  AIK81202.1  117 aa hypothetical protein 9.5e-12 ●○○○○ -0.38 -0.383990952580129
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3753  WP_000202926.1  E8XF98  913 aa ABC transporter ATP-binding protein/permease 0.042 ●○○○○ -0.38 -0.383555528643269
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1160  NP_230805.1  Q9KSU6  329 aa hypothetical protein 5.8e-5 ●○○○○ -0.38 -0.382129002982045
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1851  AIK80457.1  246 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein 0.0085 ●○○○○ -0.38 -0.382026994106779
Escherichia coli M12  CO715_24310  ATI08559.1  910 aa type VI secretion system ATPase TssH 2.2e-21 ●○○○○ -0.38 -0.381940340860949
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3414  AIK81972.1  396 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.38 -0.381494315011062
Escherichia coli M12  CO715_03000  ATI04796.1  283 aa pyridoxine kinase 0.0011 ●○○○○ -0.38 -0.381105756803953
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2677  AIK81270.1  84 aa hypothetical protein 0.023 ●○○○○ -0.38 -0.380839198399888
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4629  AIK83163.1  478 aa MFS transporter, sugar porter family protein 1.1e-16 ●○○○○ -0.38 -0.379932523453201
Retrieved entries 5,801–5,900 out of 36,363 total in 8.5 ms (Link to these results)