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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_21440  ATI08064.1  416 aa NupC/NupG family nucleoside CNT transporter 1.8e-23 ●●○○○ -1.11 -1.10928034653248
Escherichia coli M12  CO715_23925  ATI08488.1  501 aa glycerol-3-phosphate dehydrogenase 0.00014 ●●○○○ -1.11 -1.10844576247548
Escherichia coli M12  CO715_19925  ATI07786.1  566 aa hypothetical protein 7.1e-12 ●●○○○ -1.11 -1.10656794834724
Escherichia coli M12  CO715_00165  ATI04286.1  458 aa exodeoxyribonuclease 7 large subunit 2.5e-65 ●●○○○ -1.11 -1.10531607226175
Escherichia coli M12  CO715_19035  ATI07625.1  197 aa tellurite resistance methyltransferase TehB 1.4e-13 ●●○○○ -1.1 -1.10489878023325
Escherichia coli M12  CO715_16080  ATI07096.1  220 aa carbonic anhydrase 1.8e-10 ●●○○○ -1.1 -1.10239502806227
Escherichia coli M12  CO715_17005  ATI08844.1  116 aa protein HypA 0.0038 ●●○○○ -1.1 -1.10072585994828
Escherichia coli M12  CO715_06345  ATI05372.1  306 aa peptide ABC transporter permease 1.5e-25 ●●○○○ -1.1 -1.10030856791978
Escherichia coli M12  CO715_20950  ATI07977.1  356 aa phosphate acyltransferase 2.7e-8 ●●○○○ -1.1 -1.10009992190553
Escherichia coli M12  CO715_12495  ATI06451.1  220 aa DedA family protein 2.9e-49 ●●○○○ -1.1 -1.09926533784853
Escherichia coli M12  CO715_07460  ATI05565.1  546 aa paraquat-inducible protein B 9.4e-16 ●●○○○ -1.1 -1.09926533784853
Escherichia coli M12  CO715_06980  ATI05480.1  319 aa DUF1722 domain-containing protein 1.8e-113 ●●○○○ -1.1 -1.09905669183428
Escherichia coli M12  CO715_07325  ATI05541.1  285 aa hydrogenase expression/formation protein 5.3e-6 ●●○○○ -1.1 -1.09884804582004
Escherichia coli M12  CO715_05580  ATI05246.1  290 aa hypothetical protein 3.2e-7 ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_08300  ATI05714.1  234 aa leucyl/phenylalanyl-tRNA--protein transferase 4.3e-5 ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_12470  ATI06448.1  183 aa YgjV family protein 7.2e-5 ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_03410  ATI04867.1  183 aa endonuclease SmrB 3.3e-5 ●●○○○ -1.1 -1.09780481574879
Escherichia coli M12  CO715_04680  ATI05092.1  80 aa DsrB protein 0.00023 ●●○○○ -1.1 -1.0961356476348
Escherichia coli M12  CO715_08795  ATI05803.1  225 aa PKHD-type hydroxylase 4.5e-5 ●●○○○ -1.1 -1.0957183556063
Escherichia coli M12  CO715_02345  ATI04674.1  402 aa O-antigen ligase RfaL 6.0e-33 ●●○○○ -1.1 -1.09550970959205
Escherichia coli M12  CO715_12065  ATI06378.1  254 aa glc operon transcriptional activator 4.4e-7 ●●○○○ -1.09 -1.09446647952081
Escherichia coli M12  CO715_12415  ATI06438.1  672 aa NADPH-dependent 2,4-dienoyl-CoA reductase 6.0e-36 ●●○○○ -1.09 -1.09404918749231
Escherichia coli M12  CO715_18020  ATI07448.1  441 aa Xaa-Pro aminopeptidase 1.2e-5 ●●○○○ -1.09 -1.09404918749231
Escherichia coli M12  CO715_21225  ATI08025.1  200 aa cytochrome c-type protein NapC 4.1e-37 ●●○○○ -1.09 -1.09050220525008
Escherichia coli M12  CO715_10350  ATI06063.1  297 aa LysR family transcriptional regulator 3.5e-23 ●●○○○ -1.09 -1.08945897517884
Escherichia coli M12  CO715_17230  ATI07306.1  286 aa electron transfer flavoprotein subunit alpha/FixB family protein 0.0019 ●●○○○ -1.09 -1.08883303713609
Escherichia coli M12  CO715_09195  ATI05871.1  140 aa hypothetical protein 2.7e-16 ●●○○○ -1.09 -1.08841574510759
Escherichia coli M12  CO715_12335  ATI06425.1  168 aa mismatch-specific DNA-glycosylase 8.1e-6 ●●○○○ -1.09 -1.0875811610506
Escherichia coli M12  CO715_00080  ATI04271.1  427 aa peptidase B 2.1e-109 ●●○○○ -1.09 -1.08737251503635
Escherichia coli M12  CO715_01355  ATI04498.1  426 aa GTPase HflX 8.4e-77 ●●○○○ -1.08 -1.08466011685111
Escherichia coli M12  CO715_06760  ATI05442.1  122 aa hypothetical protein 5.2e-113 ●●○○○ -1.08 -1.08278230272287
Escherichia coli M12  CO715_03535  ATI04891.1  238 aa amino acid ABC transporter permease 2.3e-18 ●●○○○ -1.08 -1.07986125852339
Escherichia coli M12  CO715_19990  ATI07799.1  192 aa hypothetical protein 5.1e-13 ●●○○○ -1.08 -1.07881802845215
Escherichia coli M12  CO715_12980  ATI06540.1  97 aa phospholipid ABC transporter-binding protein 1.3e-35 ●●○○○ -1.08 -1.07798344439515
Escherichia coli M12  CO715_01770  ATI04569.1  226 aa phosphonate C-P lyase system protein PhnL 3.8e-60 ●●○○○ -1.08 -1.07547969222416
Escherichia coli M12  CO715_13320  ATI06602.1  80 aa hypothetical protein 6.0e-5 ●●○○○ -1.08 -1.07547969222416
Escherichia coli M12  CO715_14370  ATI06787.1  98 aa ArsR family transcriptional regulator 2.9e-83 ●●○○○ -1.07 -1.07318458606743
Escherichia coli M12  CO715_08550  ATI05759.1  402 aa MFS transporter 3.8e-81 ●●○○○ -1.07 -1.07151541795344
Escherichia coli M12  CO715_14430  ATI06799.1  489 aa MFS transporter 4.1e-79 ●●○○○ -1.07 -1.07130677193919
Escherichia coli M12  CO715_11115  ATI06203.1  116 aa PTS N N'-diacetylchitobiose transporter subunit IIA 3.9e-11 ●●○○○ -1.07 -1.07047218788219
Escherichia coli M12  CO715_04505  ATI05064.1  525 aa (2,3-dihydroxybenzoyl)adenylate synthase 6.4e-13 ●●○○○ -1.07 -1.07005489585369
Escherichia coli M12  CO715_02500  ATI04703.1  569 aa AsmA family protein 4.5e-7 ●●○○○ -1.07 -1.0696376038252
Escherichia coli M12  CO715_08555  ATI05760.1  271 aa Cof-type HAD-IIB family hydrolase 5.1e-78 ●●○○○ -1.07 -1.0688030197682
Escherichia coli M12  CO715_22320  ATI08226.1  239 aa LysR family transcriptional regulator 0.0075 ●●○○○ -1.07 -1.06629926759721
Escherichia coli M12  CO715_02305  ATI04666.1  319 aa hypothetical protein 2.6e-94 ●●○○○ -1.07 -1.06546468354022
Escherichia coli M12  CO715_11235  ATI06225.1  435 aa sulfurtransferase 4.8e-11 ●●○○○ -1.07 -1.06525603752597
Escherichia coli M12  CO715_02835  ATI04766.1  159 aa ethanolamine utilization acetate kinase EutP 8.9e-32 ●●○○○ -1.06 -1.06337822339773
Escherichia coli M12  CO715_17465  ATI07348.1  417 aa N-acetylmuramoyl-L-alanine amidase 8.1e-14 ●●○○○ -1.06 -1.06233499332649
Escherichia coli M12  CO715_10980  ATI06176.1  154 aa lipoprotein 1.9e-20 ●●○○○ -1.06 -1.06191770129799
Escherichia coli M12  CO715_08015  ATI05661.1  419 aa DUF1116 domain-containing protein 2.8e-9 ●●○○○ -1.06 -1.06129176325524
Escherichia coli M12  CO715_01985  ATI04609.1  180 aa hypothetical protein 3.2e-30 ●●○○○ -1.06 -1.060248533184
Escherichia coli M12  CO715_14690  ATI06849.1  208 aa lysoplasmalogenase 7.2e-8 ●●○○○ -1.06 -1.06003988716975
Escherichia coli M12  CO715_21230  ATI08026.1  207 aa cytochrome c biogenesis ATP-binding export protein CcmA 1.2e-5 ●●○○○ -1.06 -1.06003988716975
Escherichia coli M12  CO715_20645  ATI07920.1  245 aa phosphatase 0.0004 ●●○○○ -1.06 -1.0598312411555
Escherichia coli M12  CO715_10580  ATI06104.1  500 aa MFS transporter 0.011 ●●○○○ -1.06 -1.0598312411555
Escherichia coli M12  CO715_16060  ATI07092.1  409 aa polysaccharide deacetylase family protein 5.9e-58 ●●○○○ -1.06 -1.05920530311275
Escherichia coli M12  CO715_17170  ATI07295.1  178 aa type I-E CRISPR-associated protein Cse2/CasB 4.0e-24 ●●○○○ -1.06 -1.05857936507001
Escherichia coli M12  CO715_25160  ATI08678.1  216 aa transposase 1.6e-69 ●●○○○ -1.06 -1.05774478101301
Escherichia coli M12  CO715_09630  ATI05944.1  483 aa molecular chaperone DnaJ 2.2e-21 ●●○○○ -1.06 -1.05732748898451
Escherichia coli M12  CO715_20045  ATI07810.1  482 aa tRNA 4-thiouridine(8) synthase ThiI 2.3e-18 ●●○○○ -1.06 -1.05691019695601
Escherichia coli M12  CO715_20200  ATI08873.1  303 aa recombination-associated protein RdgC 1.5e-25 ●●○○○ -1.06 -1.05649290492752
Escherichia coli M12  CO715_09165  ATI05865.1  134 aa acyl-CoA thioester hydrolase YbgC 0.014 ●●○○○ -1.06 -1.05607561289902
Escherichia coli M12  CO715_05285  ATI05193.1  266 aa trehalose-phosphatase 8.6e-8 ●●○○○ -1.05 -1.05482373681353
Escherichia coli M12  CO715_21235  ATI08027.1  220 aa heme exporter protein B 0.0067 ●●○○○ -1.05 -1.05482373681353
Escherichia coli M12  CO715_05280  ATI05192.1  328 aa arabinose ABC transporter permease 4.4e-11 ●●○○○ -1.05 -1.05461509079928
Escherichia coli M12  CO715_08875  ATI05817.1  413 aa cardiolipin synthase B 5.0e-5 ●●○○○ -1.05 -1.05398915275653
Escherichia coli M12  CO715_19795  ATI07762.1  183 aa adenine phosphoribosyltransferase 9.6e-6 ●●○○○ -1.05 -1.05336321471378
Escherichia coli M12  CO715_08710  ATI05788.1  306 aa transpeptidase 2.6e-13 ●●○○○ -1.05 -1.05273727667104
Escherichia coli M12  CO715_08435  ATI05736.1  242 aa arginine ABC transporter ATP-binding protein ArtP 3.7e-18 ●●○○○ -1.05 -1.05252863065679
Escherichia coli M12  CO715_08095  ATI05675.1  615 aa L,D-transpeptidase 2.1e-41 ●●○○○ -1.05 -1.05231998464254
Escherichia coli M12  CO715_19045  ATI07627.1  326 aa hypothetical protein 7.8e-5 ●●○○○ -1.05 -1.05231998464254
Escherichia coli M12  CO715_06145  ATI05335.1  530 aa autoinducer-2 kinase 8.8e-56 ●●○○○ -1.05 -1.05190269261404
Escherichia coli M12  CO715_17565  ATI07367.1  343 aa transcriptional regulator 5.1e-8 ●●○○○ -1.05 -1.05190269261404
Escherichia coli M12  CO715_20030  ATI07807.1  163 aa nucleotide-binding protein 3.1e-10 ●●○○○ -1.05 -1.05148540058554
Escherichia coli M12  CO715_02960  ATI04788.1  285 aa MurR/RpiR family transcriptional regulator 0.00036 ●●○○○ -1.05 -1.05106810855705
Escherichia coli M12  CO715_17210  ATI07302.1  121 aa 6-carboxytetrahydropterin synthase QueD 3.5e-18 ●●○○○ -1.05 -1.04981623247155
Escherichia coli M12  CO715_02685  ATI04738.1  181 aa hydrogenase 4 subunit H 5.7e-6 ●●○○○ -1.05 -1.04981623247155
Escherichia coli M12  CO715_14220  ATI06760.1  176 aa RNA 2',3'-cyclic phosphodiesterase 1.9e-5 ●●○○○ -1.05 -1.0496075864573
Escherichia coli M12  CO715_07140  ATI05511.1  416 aa isocitrate dehydrogenase (NADP(+)) 8.4e-31 ●●○○○ -1.05 -1.04939894044306
Escherichia coli M12  CO715_07665  ATI05604.1  807 aa oxygen-sensing cyclic-di-GMP phosphodiesterase 6.8e-12 ●●○○○ -1.05 -1.04939894044306
Escherichia coli M12  CO715_12500  ATI06452.1  127 aa modulator protein MzrA 3.0e-5 ●●○○○ -1.05 -1.04877300240031
Escherichia coli M12  CO715_19620  ATI07733.1  520 aa anthranilate synthase component I 1.9e-15 ●●○○○ -1.05 -1.04814706435756
Escherichia coli M12  CO715_17370  ATI07332.1  455 aa L-serine ammonia-lyase 3.8e-9 ●●○○○ -1.05 -1.04585195820083
Escherichia coli M12  CO715_19085  ATI07634.1  546 aa methyl-accepting chemotaxis protein 6.8e-57 ●●○○○ -1.04 -1.04480872812958
Escherichia coli M12  CO715_17085  ATI07279.1  379 aa murein hydrolase activator NlpD 1.7e-16 ●●○○○ -1.04 -1.04355685204409
Escherichia coli M12  CO715_01680  ATI04554.1  222 aa two-component system response regulator BasR 5.1e-33 ●●○○○ -1.04 -1.04293091400134
Escherichia coli M12  CO715_07350  ATI05546.1  372 aa hydrogenase-1 small chain 5.5e-50 ●●○○○ -1.04 -1.04272226798709
Escherichia coli M12  CO715_06300  ATI05363.1  98 aa hypothetical protein 1.2e-47 ●●○○○ -1.04 -1.04251362197284
Escherichia coli M12  CO715_21215  ATI08023.1  287 aa quinol dehydrogenase ferredoxin subunit NapH 0.00048 ●●○○○ -1.04 -1.04251362197284
Escherichia coli M12  CO715_06580  ATI05409.1  955 aa outer membrane autotransporter barrel domain-containing protein 4.3e-122 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_19495  ATI07711.1  249 aa DeoR family transcriptional regulator 1.2e-86 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_08720  ATI05790.1  155 aa transcriptional regulator MntR 5.9e-9 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_17535  ATI07362.1  229 aa DNA mismatch repair protein MutH 3.2e-21 ●●○○○ -1.04 -1.04167903791585
Escherichia coli M12  CO715_14225  ATI06761.1  234 aa DNA/RNA nuclease SfsA 4.8e-17 ●●○○○ -1.04 -1.04021851581611
Escherichia coli M12  CO715_11275  ATI06233.1  183 aa NAD(P)H nitroreductase 5.0e-55 ●●○○○ -1.04 -1.04000986980186
Escherichia coli M12  CO715_19940  ATI07789.1  123 aa hypothetical protein 8.5e-13 ●●○○○ -1.04 -1.03980122378761
Escherichia coli M12  CO715_01495  ATI04521.1  342 aa EF-P beta-lysylation protein EpmB 7.3e-11 ●●○○○ -1.04 -1.03604559553113
Escherichia coli M12  CO715_15580  ATI07007.1  367 aa glycerol dehydrogenase 5.3e-6 ●●○○○ -1.04 -1.03541965748838
Escherichia coli M12  CO715_05775  ATI05276.1  439 aa capsid assembly protein 2.5e-14 ●●○○○ -1.03 -1.03458507343139
Escherichia coli M12  CO715_17695  ATI07389.1  244 aa EscJ/YscJ/HrcJ family type III secretion inner membrane ring protein 9.2e-31 ●●○○○ -1.03 -1.03416778140289
Retrieved entries 1,001–1,100 out of 3,550 total in 136.4 ms (Link to these results)