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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_04730  ATI05102.1  147 aa flagella biosynthesis chaperone FliJ 1.0e-11 ●●○○○ -1.83 -1.83203013989053
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0333  WP_000189588.1  E8XJM0  frsA  414 aa esterase FrsA 0.00035 ●●○○○ -1.83 -1.83187055595973
Escherichia coli O157:H7 str. EDL933  Z0942  AAG55100.1  761 aa putative enzyme 0.033 ●●○○○ -1.83 -1.83184731697758
Escherichia coli M12  CO715_16355  ATI07147.1  363 aa 3-isopropylmalate dehydrogenase 1.5e-8 ●●○○○ -1.83 -1.83161284786204
Mycobacterium avium subsp. paratuberculosis K10  MAP_3343c  AAS05893.1  Q73UM3  desA3  427 aa DesA3_1 0.024 ●●○○○ -1.83 -1.83101241300862
Escherichia coli M12  CO715_09880  ATI05990.1  386 aa pyridoxal phosphate-dependent aminotransferase 2.3e-7 ●●○○○ -1.83 -1.83056961779079
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1491  NP_231132.1  Q9KRZ2  pyrD  336 aa dihydroorotate dehydrogenase 2 6.9e-6 ●●○○○ -1.83 -1.83026962189408
Escherichia coli O157:H7 str. EDL933  Z3634  AAG57497.1  89 aa hypothetical protein 0.033 ●●○○○ -1.83 -1.83011318578229
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2376  WP_000660244.1  E8XEC2  396 aa MFS transporter 1.7e-26 ●●○○○ -1.83 -1.82971124326668
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3784  WP_001266339.1  E8XFC8  yhjK  668 aa biofilm formation regulator HmsP 0.00023 ●●○○○ -1.83 -1.8294496893681
Acinetobacter baumannii ATCC 17978  A1S_1572  ABO11999.2  557 aa 30S ribosomal protein S1 5.8e-9 ●●○○○ -1.83 -1.82931438570632
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3054  WP_001165740.1  E8XL42  316 aa SDR family oxidoreductase 3.2e-5 ●●○○○ -1.83 -1.8284167573251
Escherichia coli M12  CO715_06065  ATI05321.1  308 aa glutaminase 5.2e-27 ●●○○○ -1.83 -1.82785721960556
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1987  WP_001087453.1  E8XA98  fliA  239 aa RNA polymerase sigma factor FliA 1.2e-7 ●●○○○ -1.83 -1.82701830094089
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1125  WP_002856038.1  A1W094  clpS  96 aa ATP-dependent Clp protease adaptor ClpS 0.039 ●●○○○ -1.83 -1.8264952585
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3119  WP_000440819.1  E8X8Q8  fucA  215 aa L-fuculose-phosphate aldolase 0.00027 ●●○○○ -1.83 -1.82605954106174
Escherichia coli O157:H7 str. EDL933  Z4497  AAG58274.1  169 aa putative galactosamine-6-phosphate isomerase 0.034 ●●○○○ -1.83 -1.8253322792342
Escherichia coli O157:H7 str. EDL933  Z5946  AAG59529.1  584 aa putative restriction modification enzyme S subunit 0.034 ●●○○○ -1.82 -1.82291690361684
Escherichia coli O157:H7 str. EDL933  Z0018  AAG54317.1  388 aa Na+/H antiporter, pH dependent 0.034 ●●○○○ -1.82 -1.82228043475831
Escherichia coli M12  CO715_18335  ATI07503.1  96 aa YggU family protein 0.00013 ●●○○○ -1.82 -1.82222377722084
Escherichia coli M12  CO715_10635  ATI06113.1  670 aa FUSC family protein 1.1e-26 ●●○○○ -1.82 -1.82013731707835
Streptococcus pyogenes M1 5448  SP5448_03280  WP_002983837.1  175 aa DNA starvation/stationary phase protection protein 0.025 ●●○○○ -1.82 -1.81998654915569
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3271  AIK81832.1  382 aa lactaldehyde reductase <1e-323 ●●○○○ -1.82 -1.81971336413785
Escherichia coli CFT073  c2090  AAN80550.1  P0A9U9  ydiO  401 aa Hypothetical protein ydiO 0.046 ●●○○○ -1.82 -1.81813194001185
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1140  WP_000557256.1  E8XER3  csgC  108 aa curli assembly protein CsgC 7.4e-5 ●●○○○ -1.82 -1.81706483142527
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0517  WP_002857358.1  A0A0H3PBP7  124 aa YkgJ family cysteine cluster protein 0.04 ●●○○○ -1.82 -1.81687922744
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3766  WP_000702755.1  E8XFB1  347 aa type II asparaginase 0.00039 ●●○○○ -1.82 -1.81672833366117
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1768  NP_231403.1  Q9KR75  462 aa hypothetical protein 0.0016 ●●○○○ -1.82 -1.81643910495399
Escherichia coli O157:H7 str. EDL933  Z0955  AAG55111.1  319 aa unknown protein encoded by prophage CP-933K 0.034 ●●○○○ -1.82 -1.81623027211297
Escherichia coli M12  CO715_11600  ATI06293.1  47 aa DUF2627 domain-containing protein 5.9e-11 ●●○○○ -1.81 -1.81492116672213
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0069  WP_000597287.1  E8XG88  carA  382 aa carbamoyl-phosphate synthase small subunit 0.00032 ●●○○○ -1.81 -1.81462283132102
Escherichia coli M12  CO715_22240  ATI08212.1  450 aa O-antigen assembly polymerase 0.018 ●●○○○ -1.81 -1.81387793665088
Escherichia coli M12  CO715_03130  ATI04816.1  321 aa glucokinase 8.0e-12 ●●○○○ -1.81 -1.81325199860814
Escherichia coli M12  CO715_08125  ATI05681.1  259 aa envelope biogenesis factor ElyC 1.9e-7 ●●○○○ -1.81 -1.81325199860814
Escherichia coli M12  CO715_17985  ATI07442.1  103 aa ASCH domain-containing protein 0.0062 ●●○○○ -1.81 -1.81283470657964
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0777  NP_233163.1  Q9KLG7  236 aa hypothetical protein 5.1e-9 ●●○○○ -1.81 -1.81212874738621
Escherichia coli M12  CO715_00960  ATI04427.1  249 aa hypothetical protein 2.2e-8 ●●○○○ -1.81 -1.8113741844799
Streptococcus pyogenes M1 5448  SP5448_06675  WP_002985249.1  65 aa F0F1 ATP synthase subunit C 0.0083 ●●○○○ -1.81 -1.81133452067311
Acinetobacter baumannii ATCC 17978  A1S_1452  ABO11880.2  142 aa arsenate reductase 0.00031 ●●○○○ -1.81 -1.81061506325059
Escherichia coli M12  CO715_10330  ATI06059.1  204 aa Tat proofreading chaperone DmsD 1.0e-6 ●●○○○ -1.81 -1.81033095440865
Mycobacterium avium subsp. paratuberculosis K10  MAP_1519  AAS03836.1  Q73ZT2  467 aa hypothetical protein 0.025 ●●○○○ -1.81 -1.80940716294378
Escherichia coli M12  CO715_14720  ATI06855.1  352 aa ABC transporter permease 5.6e-12 ●●○○○ -1.81 -1.80907907832316
Escherichia coli M12  CO715_13550  ATI06640.1  145 aa hypothetical protein 3.9e-10 ●●○○○ -1.81 -1.80824449426616
Escherichia coli M12  CO715_14630  ATI06838.1  85 aa acyl carrier protein 1.1e-6 ●●○○○ -1.8 -1.80428021999544
Escherichia coli M12  CO715_04340  ATI05042.1  139 aa zinc resistance-associated protein 2.5e-10 ●●○○○ -1.8 -1.80302834390994
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4159  WP_000669905.1  E8XJG9  607 aa arylsulfatase 2.8e-5 ●●○○○ -1.8 -1.80165631336541
Escherichia coli M12  CO715_05420  ATI05217.1  272 aa hypothetical protein 4.5e-14 ●●○○○ -1.8 -1.8011505297817
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4125  AIK82671.1  663 aa transketolase 0.013 ●●○○○ -1.8 -1.80093813984857
Escherichia coli M12  CO715_11185  ATI06216.1  406 aa succinylornithine aminotransferase 5.0e-20 ●●○○○ -1.8 -1.80073323775321
Mycobacterium avium subsp. paratuberculosis K10  MAP_2670c  AAS04987.1  Q73WJ0  gnd2  340 aa Gnd2 0.026 ●●○○○ -1.8 -1.80014132262909
Mycobacterium avium subsp. paratuberculosis K10  MAP_0473c  AAS02790.1  Q743W8  radA  474 aa RadA 0.026 ●●○○○ -1.8 -1.79999567967189
Acinetobacter baumannii ATCC 17978  A1S_0530  ABO10983.2  138 aa hypothetical protein 2.3e-12 ●●○○○ -1.8 -1.79979844964672
Escherichia coli M12  CO715_04945  ATI05136.1  414 aa flippase 0.019 ●●○○○ -1.8 -1.79969000768196
Escherichia coli M12  CO715_01450  ATI04512.1  244 aa fumarate reductase iron-sulfur subunit 7.0e-24 ●●○○○ -1.8 -1.79864677761072
Escherichia coli M12  CO715_09520  ATI05930.1  554 aa asparagine synthetase B 3.4e-8 ●●○○○ -1.8 -1.79843813159647
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3448  WP_014343910.1  E8XCA6  argG  469 aa argininosuccinate synthase 0.00052 ●●○○○ -1.8 -1.79760315803019
Escherichia coli M12  CO715_08910  ATI05824.1  170 aa molybdenum cofactor biosynthesis protein 2.3e-16 ●●○○○ -1.8 -1.79697760949673
Streptococcus pyogenes M1 5448  SP5448_08975  WP_010922737.1  557 aa formate--tetrahydrofolate ligase 0.047 ●●○○○ -1.8 -1.79691447320214
Escherichia coli M12  CO715_19740  ATI07752.1  406 aa MFS transporter 1.7e-23 ●●○○○ -1.8 -1.79656031746823
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1427  WP_002869409.1  A0A0H3PBA7  fcl  352 aa GDP-L-fucose synthase 0.041 ●●○○○ -1.8 -1.79655983643
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0155  WP_002883441.1  A0A0H3PAY5  204 aa recombination protein RecO 0.041 ●●○○○ -1.8 -1.7955212287
Mycobacterium avium subsp. paratuberculosis K10  MAP_3735c  AAS06285.1  Q73TI3  429 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.79459175622204
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3590  AIK82145.1  639 aa putative zinc-dependent peptidase 3.8e-11 ●●○○○ -1.79 -1.79457275415617
Mycobacterium avium subsp. paratuberculosis K10  MAP_3034  AAS05582.1  Q73VH9  475 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.79414661386746
Mycobacterium avium subsp. paratuberculosis K10  MAP_2622  AAS04939.1  Q73WN8  314 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.79375292074305
Mycobacterium avium subsp. paratuberculosis K10  MAP_1085  AAS03402.1  Q741K5  406 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.79228512877462
Acinetobacter baumannii ATCC 17978  A1S_1468  ABO11896.2  476 aa putative PLP-dependent aminotransferase 9.8e-26 ●●○○○ -1.79 -1.79224590562603
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4565  WP_000076357.1  E8XAP4  rnr  812 aa ribonuclease R 3.1e-12 ●●○○○ -1.79 -1.7916374818602
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3812  WP_000395013.1  E8XFV5  lpfA  178 aa long polar fimbrial protein LpfA 6.4e-7 ●●○○○ -1.79 -1.79105888113045
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0814  NP_230463.1  Q9KTS4  159 aa transcriptional regulator 3.8e-8 ●●○○○ -1.79 -1.7906548971232
Mycobacterium avium subsp. paratuberculosis K10  MAP_2249c  AAS04566.1  Q73XR0  154 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.790034151382
Mycobacterium avium subsp. paratuberculosis K10  MAP_2120c  AAS04437.1  Q9KII6  670 aa hypothetical protein 0.026 ●●○○○ -1.79 -1.78941954676838
Escherichia coli M12  CO715_21630  ATI08098.1  385 aa osmoprotectant uptake system permease 6.7e-7 ●●○○○ -1.79 -1.78821447689827
Escherichia coli M12  CO715_05460  ATI05224.1  203 aa Holliday junction branch migration protein RuvA 0.019 ●●○○○ -1.79 -1.78821447689827
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1627  WP_000118615.1  E8XJU5  268 aa BtpA family protein SgcQ 1.1e-25 ●●○○○ -1.79 -1.78636222942051
Streptococcus pyogenes M1 5448  SP5448_05305  WP_002984674.1  427 aa purine permease 0.025 ●●○○○ -1.79 -1.78537843522536
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1742  AIK80362.1  143 aa universal stress protein UP12 2.3e-5 ●●○○○ -1.79 -1.78520294741972
Escherichia coli M12  CO715_05130  ATI05167.1  136 aa flagella export chaperone FliS 2.9e-5 ●●○○○ -1.78 -1.78487614067029
Escherichia coli M12  CO715_20020  ATI07805.1  296 aa protoheme IX farnesyltransferase 5.8e-6 ●●○○○ -1.78 -1.7836242645848
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3861  AIK82411.1  90 aa phosphocarrier, HPr family protein 7.2e-13 ●●○○○ -1.78 -1.78359494815035
Escherichia coli M12  CO715_18245  ATI07487.1  306 aa agmatinase 4.6e-16 ●●○○○ -1.78 -1.78341561857055
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1776  WP_001212712.1  E8XKX4  509 aa sel1 repeat family protein 1.0e-8 ●●○○○ -1.78 -1.78325248509851
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0415  WP_000113921.1  E8XKI2  phoB  229 aa phosphate response regulator transcription factor PhoB 0.00043 ●●○○○ -1.78 -1.78276315353091
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1601  WP_001119592.1  E8XJ36  yncC  221 aa GntR family transcriptional regulator 7.2e-13 ●●○○○ -1.78 -1.78263933903411
Escherichia coli M12  CO715_06125  ATI05331.1  330 aa autoinducer 2 import system permease LsrD 3.3e-5 ●●○○○ -1.78 -1.78258103451355
Escherichia coli M12  CO715_01160  ATI08702.1  273 aa ribose ABC transporter permease 4.4e-6 ●●○○○ -1.78 -1.78132915842806
Escherichia coli M12  CO715_24190  ATI08539.1  180 aa hypothetical protein 0.00022 ●●○○○ -1.78 -1.78049457437107
Escherichia coli M12  CO715_04425  ATI05052.1  310 aa L,D-transpeptidase 4.6e-28 ●●○○○ -1.78 -1.77986863632832
Mycobacterium avium subsp. paratuberculosis K10  MAP_3634  AAS06184.1  Q73TT4  345 aa hypothetical protein 0.027 ●●○○○ -1.78 -1.77884188954705
Escherichia coli O157:H7 str. EDL933  Z1886  AAG55983.1  439 aa putative capsid protein of prophage CP-933X 0.037 ●●○○○ -1.78 -1.77869323684424
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4843  AIK83370.1  325 aa NADH:ubiquinone oxidoreductase, membrane subunitH 0.013 ●●○○○ -1.78 -1.77771773998676
Escherichia coli M12  CO715_17025  ATI07267.1  336 aa hydrogenase expression/formation protein HypE 1.5e-12 ●●○○○ -1.78 -1.77757353017158
Escherichia coli M12  CO715_05035  ATI05153.1  434 aa histidinol dehydrogenase 4.6e-20 ●●○○○ -1.78 -1.77694759212884
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0285  CBW16386.1  A0A0H3NHS6  sciW  148 aa conserved hypothetical protein (SPI-6 associated) 0.0016 ●●○○○ -1.78 -1.77643290428037
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3021  WP_000258811.1  E8XL10  sipA  685 aa SPI-1 type III secretion system effector SipA 3.3e-5 ●●○○○ -1.78 -1.77518851779261
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2262  NP_231893.1  Q9KPV0  glnD  881 aa PII uridylyl-transferase 4.9e-8 ●●○○○ -1.78 -1.77510145890701
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4259  WP_000090737.1  E8XKE4  yneA  340 aa autoinducer 2 ABC transporter substrate-binding protein LsrB 7.0e-8 ●●○○○ -1.78 -1.77502080302575
Escherichia coli M12  CO715_08180  ATI05692.1  254 aa metalloprotease 3.8e-8 ●●○○○ -1.77 -1.77360925590085
Mycobacterium avium subsp. paratuberculosis K10  MAP_0020c  AAS02337.1  Q744R2  rodA  469 aa RodA 0.027 ●●○○○ -1.77 -1.77321139686323
Mycobacterium avium subsp. paratuberculosis K10  MAP_2000  AAS04317.1  Q73YF6  accD6  473 aa AccD6 0.027 ●●○○○ -1.77 -1.77287973013787
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