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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_13935  ATI06708.1  190 aa D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase 0.02 ●●○○○ -1.77 -1.77277467184386
Mycobacterium avium subsp. paratuberculosis K10  MAP_4282  AAS06832.1  Q73RZ6  273 aa hypothetical protein 0.027 ●●○○○ -1.77 -1.77276655308453
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4601  AIK83136.1  539 aa L-aspartate oxidase <1e-323 ●●○○○ -1.77 -1.77188296769045
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1573  AIK80193.1  73 aa cold shock domain protein CspD 0.00027 ●●○○○ -1.77 -1.77105179780836
Escherichia coli M12  CO715_03990  ATI04974.1  428 aa cell division protein DamX 4.6e-8 ●●○○○ -1.77 -1.76985362764437
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0262  WP_002851887.1  A0A0H3PAX6  cynT  211 aa carbonic anhydrase 0.043 ●●○○○ -1.77 -1.7698533635
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3032  CBW19131.1  A0A0H3NLV3  visC  400 aa possible monooxygenase 0.0018 ●●○○○ -1.77 -1.7690922553197
Escherichia coli M12  CO715_02680  ATI04737.1  252 aa formate hydrogenlyase 5.6e-14 ●●○○○ -1.77 -1.76839310554463
Escherichia coli M12  CO715_17870  ATI07419.1  1032 aa putative selenate reductase subunit YgfK 7.4e-6 ●●○○○ -1.77 -1.76797581351613
Acinetobacter baumannii ATCC 17978  A1S_2389  ABO12808.2  313 aa putative ferric acinetobactin transport system permease protein 1.7e-9 ●●○○○ -1.77 -1.76748685123479
Escherichia coli O157:H7 str. EDL933  Z2206  AAG56266.1  304 aa putative adhesin; similar to FimH protein 0.038 ●●○○○ -1.77 -1.76665355929076
Mycobacterium avium subsp. paratuberculosis K10  MAP_1601  AAS03918.1  Q73ZK2  426 aa hypothetical protein 0.028 ●●○○○ -1.77 -1.76529223880439
Escherichia coli M12  CO715_11610  ATI06294.1  95 aa hypothetical protein 9.3e-11 ●●○○○ -1.76 -1.7648461233024
Mycobacterium avium subsp. paratuberculosis K10  MAP_1723  AAS04040.1  Q73Z80  221 aa hypothetical protein 0.028 ●●○○○ -1.76 -1.76413121364339
Escherichia coli M12  CO715_02140  ATI04637.1  549 aa glucose-6-phosphate isomerase 6.5e-36 ●●○○○ -1.76 -1.76380289323116
Mycobacterium avium subsp. paratuberculosis K10  MAP_3103c  AAS05651.1  Q73VB1  88 aa hypothetical protein 0.028 ●●○○○ -1.76 -1.7635576385501
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0071  WP_000333324.1  E8XG90  caiF  131 aa carnitine metabolism transcriptional regulator CaiF 3.7e-11 ●●○○○ -1.76 -1.76332385065613
Escherichia coli M12  CO715_03645  ATI04913.1  600 aa NADH-quinone oxidoreductase subunit C/D 3.7e-15 ●●○○○ -1.76 -1.76317695518841
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1356  WP_009882907.1  Q6QNL7  93 aa type II toxin-antitoxin system RelE/ParE family toxin 0.044 ●●○○○ -1.76 -1.76287540228
Streptococcus pyogenes M1 5448  SP5448_00790  WP_002986446.1  121 aa RidA family protein 0.036 ●●○○○ -1.76 -1.7623063592718
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4002  WP_001202030.1  E8XHR1  torT  346 aa TMAO reductase system periplasmic protein TorT 4.0e-5 ●●○○○ -1.76 -1.76220180732264
Escherichia coli M12  CO715_02200  ATI04648.1  409 aa L-sorbose 1-phosphate reductase 1.5e-8 ●●○○○ -1.76 -1.76171643308867
Mycobacterium avium subsp. paratuberculosis K10  MAP_0376c  AAS02693.1  Q744G5  207 aa hypothetical protein 0.028 ●●○○○ -1.76 -1.76142684639326
Escherichia coli M12  CO715_11525  ATI06280.1  453 aa aminodeoxychorismate synthase component 1 5.9e-32 ●●○○○ -1.76 -1.76129914106017
Acinetobacter baumannii ATCC 17978  A1S_2375  ABO12794.2  531 aa putative ABC transporter 6.9e-10 ●●○○○ -1.76 -1.76097901575648
Escherichia coli M12  CO715_22200  ATI08204.1  376 aa UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) 2.8e-22 ●●○○○ -1.76 -1.76067320301742
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4633  WP_000166287.1  E8XBI9  yjgA  183 aa ribosome-associated protein 0.0005 ●●○○○ -1.76 -1.76010573158334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3266  AIK81827.1  276 aa rhamnulose-1-phosphate aldolase 1.2e-15 ●●○○○ -1.76 -1.75973723009172
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4615  WP_000107709.1  E8XBH1  477 aa myo-inositol import MFS transporter IolT1 6.6e-15 ●●○○○ -1.76 -1.75934974748522
Escherichia coli M12  CO715_19575  ATI07725.1  83 aa hypothetical protein 8.8e-13 ●●○○○ -1.76 -1.75879538888918
Escherichia coli O157:H7 str. EDL933  Z1822  AAG55922.1  649 aa unknown protein encoded by prophage CP-933N 0.038 ●●○○○ -1.76 -1.7582071063804
Escherichia coli M12  CO715_18925  ATI07607.1  345 aa NADP-dependent oxidoreductase 2.7e-11 ●●○○○ -1.76 -1.75796080483219
Escherichia coli O157:H7 str. EDL933  Z3496  AAG57369.1  356 aa hypothetical protein 0.038 ●●○○○ -1.76 -1.75741026414139
Mycobacterium avium subsp. paratuberculosis K10  MAP_2963c  AAS05280.1  Q73VQ0  874 aa hypothetical protein 0.028 ●●○○○ -1.76 -1.75687915194876
Escherichia coli M12  CO715_06430  ATI05383.1  512 aa nitrate reductase subunit beta 2.1e-19 ●●○○○ -1.76 -1.7567089287467
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0283  WP_002857292.1  A0A0H3PBK1  512 aa lipid A/FlgG phosphoethanolamine transferase EptC 0.044 ●●○○○ -1.76 -1.75583361199
Escherichia coli M12  CO715_07515  ATI05575.1  263 aa alkanesulfonate transporter permease subunit 1.3e-13 ●●○○○ -1.76 -1.7550397606327
Acinetobacter baumannii ATCC 17978  A1S_1970  ABO12397.2  451 aa putative membrane-associated Zn-dependent proteases 1 1.1e-10 ●●○○○ -1.75 -1.75484472271155
Escherichia coli O157:H7 str. EDL933  Z5440  AAG59090.1  582 aa putative frv operon regulatory protein 0.038 ●●○○○ -1.75 -1.75269603492902
Escherichia coli M12  CO715_02700  ATI04741.1  216 aa hydrogenase 4 membrane subunit 5.9e-14 ●●○○○ -1.75 -1.75170142440472
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2497  WP_000279836.1  E8XF52  pgtC  72 aa hypothetical protein 0.00031 ●●○○○ -1.75 -1.75166679723663
Escherichia coli M12  CO715_10895  ATI06159.1  252 aa 3-dehydroquinase 9.7e-10 ●●○○○ -1.75 -1.75149277839047
Escherichia coli M12  CO715_08655  ATI05778.1  249 aa molybdopterin-synthase adenylyltransferase MoeB 2.3e-8 ●●○○○ -1.75 -1.75149277839047
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1389  WP_002855654.1  A0A0H3PDZ1  218 aa transcriptional regulator 0.045 ●●○○○ -1.75 -1.7507129109
Escherichia coli M12  CO715_09905  ATI05995.1  248 aa 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 7.4e-10 ●●○○○ -1.75 -1.75065819433348
Escherichia coli O157:H7 str. EDL933  Z5429  AAG59080.1  304 aa hypothetical protein 0.039 ●●○○○ -1.75 -1.75046961524666
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4075  WP_000379217.1  E8XIK8  yifA  278 aa HTH-type transcriptional regulator HdfR 0.00058 ●●○○○ -1.75 -1.74991376314625
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3137  WP_000011919.1  E8X8S4  amiC  417 aa N-acetylmuramoyl-L-alanine amidase 0.00059 ●●○○○ -1.75 -1.74920036077812
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4125  WP_000812765.1  E8XJD6  yigA  235 aa DUF484 domain-containing protein 0.00034 ●●○○○ -1.75 -1.74893241826983
Escherichia coli O157:H7 str. EDL933  Z4173  AAG57965.1  458 aa putative invasion protein 0.039 ●●○○○ -1.75 -1.74854896418934
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3680  AIK82235.1  109 aa thiosulfate:cyanide sulfurtransferase 1.3e-5 ●●○○○ -1.75 -1.74794707407623
Mycobacterium avium subsp. paratuberculosis K10  MAP_0573c  AAS02890.1  Q743L8  otsA  492 aa OtsA 0.028 ●●○○○ -1.75 -1.74743669246767
Mycobacterium avium subsp. paratuberculosis K10  MAP_2234  AAS04551.1  Q73XS5  376 aa hypothetical protein 0.028 ●●○○○ -1.75 -1.74742782860459
Escherichia coli M12  CO715_03840  ATI04948.1  191 aa Fe-S biogenesis protein NfuA 1.2e-8 ●●○○○ -1.75 -1.7473198581055
Escherichia coli O157:H7 str. EDL933  Z0670  AAG54872.1  261 aa orf, hypothetical protein 0.039 ●●○○○ -1.75 -1.74725671756776
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1118  WP_002852822.1  A0A0H3PGY5  145 aa hypothetical protein 0.045 ●●○○○ -1.75 -1.7472013622
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0761  WP_001048589.1  E8XAX1  sucC  388 aa ADP-forming succinate--CoA ligase subunit beta 0.00056 ●●○○○ -1.75 -1.74588962815636
Escherichia coli M12  CO715_04365  ATI05047.1  529 aa bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 1.2e-53 ●●○○○ -1.75 -1.74565068999151
Escherichia coli M12  CO715_17470  ATI07349.1  443 aa N-acetylglutamate synthase 1.7e-10 ●●○○○ -1.75 -1.74523339796301
Mycobacterium avium subsp. paratuberculosis K10  MAP_2327  AAS04644.1  Q73XI2  579 aa hypothetical protein 0.029 ●●○○○ -1.75 -1.74516655298977
Escherichia coli M12  CO715_11585  ATI06290.1  206 aa hypothetical protein 9.5e-10 ●●○○○ -1.74 -1.74481610593451
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1237  NP_230882.1  Q9KSL9  cobT  369 aa nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 7.1e-10 ●●○○○ -1.74 -1.74461135451537
Escherichia coli M12  CO715_04670  ATI05091.1  75 aa hypothetical protein 1.0e-8 ●●○○○ -1.74 -1.74439881390601
Escherichia coli M12  CO715_07260  ATI05532.1  390 aa pentaheme c-type cytochrome TorC 5.4e-12 ●●○○○ -1.74 -1.74419016789176
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1124  WP_002856169.1  A0A0H3P9C2  200 aa TlpA family protein disulfide reductase 0.045 ●●○○○ -1.74 -1.74378228107
Escherichia coli M12  CO715_20980  ATI07983.1  269 aa aminodeoxychorismate lyase 7.0e-52 ●●○○○ -1.74 -1.74335558383477
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0934  WP_002855863.1  A1VZR0  apt  182 aa adenine phosphoribosyltransferase 0.045 ●●○○○ -1.74 -1.74335187681
Escherichia coli M12  CO715_05305  ATI05197.1  192 aa flagellar transcriptional regulator FlhC 0.011 ●●○○○ -1.74 -1.74252099977777
Escherichia coli CFT073  c2797  AAN81251.1  Q8FFM1  arnA  660 aa Hypothetical protein yfbG 0.045 ●●○○○ -1.74 -1.74187972640173
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3931  WP_001143053.1  E8XGV5  misL  955 aa intestinal colonization autotransporter adhesin MisL 6.5e-5 ●●○○○ -1.74 -1.74168729447399
Escherichia coli M12  CO715_24635  ATI08614.1  202 aa glutathione S-transferase 0.00039 ●●○○○ -1.74 -1.74126912369228
Mycobacterium avium subsp. paratuberculosis K10  MAP_2765c  AAS05082.1  Q73W95  396 aa hypothetical protein 0.029 ●●○○○ -1.74 -1.74082878325283
Escherichia coli M12  CO715_08670  ATI05781.1  810 aa formate C-acetyltransferase/glycerol dehydratase family glycyl radical enzyme 1.9e-20 ●●○○○ -1.74 -1.74064318564953
Escherichia coli M12  CO715_07310  ATI08755.1  436 aa phytase AppA 5.7e-7 ●●○○○ -1.74 -1.74064318564953
Escherichia coli M12  CO715_08950  ATI05832.1  429 aa adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 4.7e-6 ●●○○○ -1.74 -1.74022589362104
Escherichia coli M12  CO715_15120  ATI06929.1  46 aa 50S ribosomal protein L36 5.2e-10 ●●○○○ -1.74 -1.74001724760679
Escherichia coli M12  CO715_20825  ATI07952.1  215 aa DUF480 domain-containing protein 1.3e-9 ●●○○○ -1.74 -1.73918266354979
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0435  WP_000543533.1  E8XKK2  nrdR  149 aa transcriptional regulator NrdR 0.00039 ●●○○○ -1.74 -1.73917804155523
Escherichia coli M12  CO715_11540  ATI06283.1  532 aa cyclic diguanylate phosphodiesterase 6.5e-22 ●●○○○ -1.74 -1.73897401753554
Acinetobacter baumannii ATCC 17978  A1S_1947  ABO12374.2  572 aa phosphotransferase system fructose-specific IIBC component 2.2e-24 ●●○○○ -1.74 -1.73880714881757
Acinetobacter baumannii ATCC 17978  A1S_2606  ABO13023.2  209 aa phosphoribosylglycinamide formyltransferase 1 2.0e-8 ●●○○○ -1.74 -1.73828726947869
Mycobacterium avium subsp. paratuberculosis K10  MAP_1159c  AAS03476.1  Q741D2  fadD12  539 aa FadD12_1 0.029 ●●○○○ -1.74 -1.73799585046972
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2975  WP_000804536.1  E8XK76  srlL  257 aa glucitol operon DNA-binding transcriptional repressor SrlR 7.4e-11 ●●○○○ -1.74 -1.73691456367653
Escherichia coli O157:H7 str. EDL933  Z2257  AAG56315.1  656 aa unknown protein associated with Rhs element 0.04 ●●○○○ -1.74 -1.73677359281928
Escherichia coli O157:H7 str. EDL933  Z4906  AAG58636.1  35 aa hypothetical protein 0.04 ●●○○○ -1.74 -1.73543895112646
Acinetobacter baumannii ATCC 17978  A1S_2387  ABO12806.2  256 aa BauE 3.6e-20 ●●○○○ -1.73 -1.73453569906357
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0080  WP_002805290.1  A0A0H3P992  flgD  294 aa flagellar basal body rod modification protein 0.046 ●●○○○ -1.73 -1.73421434438
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1229  WP_002859287.1  A0A0H3P9U2  67 aa hypothetical protein 0.046 ●●○○○ -1.73 -1.73411399792
Mycobacterium avium subsp. paratuberculosis K10  MAP_3997c  AAS06547.1  Q73SS6  serB  303 aa SerB 0.029 ●●○○○ -1.73 -1.73360357501573
Escherichia coli CFT073  c1769  AAN80235.1  P0AGH6  sapC  296 aa Peptide transport system permease protein sapC 0.033 ●●○○○ -1.73 -1.7335864746034
Escherichia coli M12  CO715_11645  ATI06300.1  122 aa bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase 1.0e-8 ●●○○○ -1.73 -1.73271463710808
Mycobacterium avium subsp. paratuberculosis K10  MAP_2998c  AAS05546.1  Q73VL5  268 aa hypothetical protein 0.029 ●●○○○ -1.73 -1.73226723967882
Mycobacterium avium subsp. paratuberculosis K10  MAP_2516  AAS04833.1  Q73WZ4  415 aa hypothetical protein 0.029 ●●○○○ -1.73 -1.73147901745036
Escherichia coli M12  CO715_01390  ATI04505.1  379 aa tRNA epoxyqueuosine(34) reductase QueG 3.6e-6 ●●○○○ -1.73 -1.73146276102258
Acinetobacter baumannii ATCC 17978  A1S_2000  ABO12427.2  757 aa hypothetical protein 3.1e-24 ●●○○○ -1.73 -1.731255979167
Escherichia coli M12  CO715_03695  ATI04923.1  485 aa NADH-quinone oxidoreductase subunit N 8.4e-12 ●●○○○ -1.73 -1.73125411500833
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4466  AIK83009.1  175 aa putative electron transport protein HydN 8.7e-10 ●●○○○ -1.73 -1.72997824922223
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1594  AIK80214.1  222 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein <1e-323 ●●○○○ -1.73 -1.72870993425433
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1087  WP_002812869.1  A0A0H3PH24  288 aa VirK family antimicrobial peptide resistance protein 0.047 ●●○○○ -1.73 -1.72854316908
Escherichia coli M12  CO715_09965  ATI06007.1  400 aa enterochelin esterase 7.4e-35 ●●○○○ -1.73 -1.7281244247946
Retrieved entries 2,201–2,300 out of 36,363 total in 721.1 ms (Link to these results)