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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2517  NP_232146.1  Q9KP59  213 aa hypothetical protein 1.2e-7 ●●○○○ -1.46 -1.46491413102617
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3412  AIK81969.1  313 aa bacterial regulatory, lacI family protein <1e-323 ●●○○○ -1.46 -1.4647588450815
Escherichia coli M12  CO715_07490  ATI05571.1  336 aa dihydroorotate dehydrogenase (quinone) 5.0e-22 ●●○○○ -1.46 -1.46460450879829
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3709  WP_000730239.1  E8XEP5  gntR  331 aa gluconate operon transcriptional repressor GntR 0.0032 ●●○○○ -1.46 -1.46455314825222
Mycobacterium avium subsp. paratuberculosis K10  MAP_0052c  AAS02369.1  Q744U9  glnQ  579 aa GlnQ 0.045 ●●○○○ -1.46 -1.46401731925201
Escherichia coli M12  CO715_16895  ATI07245.1  259 aa sorbitol 6-phosphate dehydrogenase 4.3e-5 ●●○○○ -1.46 -1.4629353406843
Escherichia coli M12  CO715_10730  ATI06131.1  213 aa riboflavin synthase 0.017 ●●○○○ -1.46 -1.46230940264155
Escherichia coli M12  CO715_10985  ATI06177.1  249 aa vitamin B12 import ATP-binding protein BtuD 1.6e-23 ●●○○○ -1.46 -1.46189211061305
Escherichia coli M12  CO715_18940  ATI07609.1  149 aa hypothetical protein 3.4e-10 ●●○○○ -1.46 -1.46126617257031
Mycobacterium avium subsp. paratuberculosis K10  MAP_0259  AAS02576.1  Q745Q7  246 aa hypothetical protein 0.045 ●●○○○ -1.46 -1.46102908888364
Escherichia coli M12  CO715_04550  ATI05073.1  434 aa salicylate synthase 2.4e-44 ●●○○○ -1.46 -1.46084888054181
Escherichia coli M12  CO715_20615  ATI07915.1  423 aa deferrochelatase/peroxidase EfeB 7.2e-7 ●●○○○ -1.46 -1.46022294249906
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0658  WP_000858711.1  E8X9Z6  dacA  403 aa D-alanyl-D-alanine carboxypeptidase DacA 0.0042 ●●○○○ -1.46 -1.45981472650121
Escherichia coli M12  CO715_08865  ATI05815.1  136 aa hypothetical protein 1.5e-15 ●●○○○ -1.46 -1.45959700445632
Escherichia coli M12  CO715_15245  ATI06949.1  298 aa sugar kinase 1.3e-8 ●●○○○ -1.46 -1.45959700445632
Escherichia coli M12  CO715_21785  ATI08128.1  248 aa transcriptional regulator 5.6e-5 ●●○○○ -1.46 -1.45959700445632
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3243  AIK81804.1  386 aa O-succinylhomoserine (thiol)-lyase <1e-323 ●●○○○ -1.46 -1.45862410251774
Mycobacterium avium subsp. paratuberculosis K10  MAP_2479  AAS04796.1  Q73X31  581 aa hypothetical protein 0.045 ●●○○○ -1.46 -1.45817825682899
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4142  AIK82688.1  364 aa glycine cleavage system T protein 2.9e-10 ●●○○○ -1.46 -1.45806312044684
Escherichia coli M12  CO715_04745  ATI05105.1  331 aa flagellar motor switch protein FliG 1.6e-7 ●●○○○ -1.46 -1.45709325228533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3932  AIK82480.1  50 aa hypothetical protein <1e-323 ●●○○○ -1.46 -1.4560982298401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1764  NP_231399.1  Q9KR79  706 aa hypothetical protein 6.0e-6 ●●○○○ -1.46 -1.4557561407866
Escherichia coli M12  CO715_11575  ATI06289.1  152 aa hypothetical protein 1.0e-14 ●●○○○ -1.46 -1.45563273018559
Escherichia coli M12  CO715_14120  ATI06742.1  890 aa bifunctional uridylyltransferase/uridylyl-removing protein 8.5e-11 ●●○○○ -1.46 -1.45563273018559
Escherichia coli M12  CO715_07840  ATI05630.1  164 aa PerC family transcriptional regulator 0.045 ●●○○○ -1.46 -1.45563273018559
Escherichia coli M12  CO715_12815  ATI06512.1  176 aa cytoplasmic protein 0.00075 ●●○○○ -1.46 -1.45521543815709
Mycobacterium avium subsp. paratuberculosis K10  MAP_0682  AAS02999.1  Q743A3  360 aa hypothetical protein 0.045 ●●○○○ -1.45 -1.45429053724866
Escherichia coli M12  CO715_15645  ATI07020.1  258 aa acetylglutamate kinase 5.1e-97 ●●○○○ -1.45 -1.45417220808585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4362  AIK82905.1  251 aa 5'-3' exonuclease, C-terminal SAM fold family protein 0.0042 ●●○○○ -1.45 -1.4539637581388
Escherichia coli M12  CO715_24260  ATI08551.1  240 aa SAM-dependent methyltransferase 0.0007 ●●○○○ -1.45 -1.4539635620716
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2546  WP_000881745.1  E8XFQ2  cysT  277 aa sulfate ABC transporter permease 0.016 ●●○○○ -1.45 -1.45395554620134
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5113  AIK83639.1  37 aa hemolysin expression modulating family protein <1e-323 ●●○○○ -1.45 -1.45392822111739
Escherichia coli M12  CO715_16945  ATI07254.1  485 aa PTS cellobiose/arbutin/salicin transporter subunit IIBC 4.6e-10 ●●○○○ -1.45 -1.4535462700431
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4342  CBW20428.1  E1WAU4  tamA  577 aa hypothetical exported protein 0.017 ●●○○○ -1.45 -1.45292865007397
Escherichia coli M12  CO715_07055  ATI05494.1  235 aa phage repressor protein C 0.045 ●●○○○ -1.45 -1.45292033200035
Escherichia coli M12  CO715_13525  ATI06636.1  226 aa hypothetical protein 6.7e-11 ●●○○○ -1.45 -1.45208574794336
Escherichia coli M12  CO715_16925  ATI07251.1  377 aa nitric oxide reductase FlRd-NAD+ reductase 2.7e-35 ●●○○○ -1.45 -1.45187710192911
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4092  WP_000047525.1  E8XIM5  rhlB  421 aa ATP-dependent RNA helicase RhlB 0.004 ●●○○○ -1.45 -1.45187338186482
Mycobacterium avium subsp. paratuberculosis K10  MAP_2844  AAS05161.1  Q73W17  468 aa hypothetical protein 0.046 ●●○○○ -1.45 -1.45104974098207
Escherichia coli M12  CO715_12825  ATI06514.1  633 aa DEAD/DEAH family ATP-dependent RNA helicase 0.00063 ●●○○○ -1.45 -1.45020793381512
Escherichia coli M12  CO715_03985  ATI04973.1  362 aa 3-dehydroquinate synthase 0.011 ●●○○○ -1.45 -1.44916470374387
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4922  AIK83448.1  376 aa phosphocarrier, HPr family protein 0.0018 ●●○○○ -1.45 -1.44907846283614
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3440  AIK81997.1  259 aa beta-lactamase superfamily domain protein 3.2e-10 ●●○○○ -1.45 -1.44859601331806
Escherichia coli M12  CO715_21455  ATI08067.1  349 aa YeiH family putative sulfate export transporter 3.9e-34 ●●○○○ -1.45 -1.44853876570113
Mycobacterium avium subsp. paratuberculosis K10  MAP_4255  AAS06805.1  Q73S21  243 aa hypothetical protein 0.046 ●●○○○ -1.45 -1.44824374523811
Escherichia coli M12  CO715_05275  ATI05191.1  504 aa L-arabinose ABC transporter ATP-binding protein AraG 7.9e-76 ●●○○○ -1.45 -1.44791282765838
Escherichia coli M12  CO715_17205  ATI07301.1  599 aa NADPH-dependent assimilatory sulfite reductase flavoprotein subunit 1.9e-23 ●●○○○ -1.45 -1.44791282765838
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4504  WP_001112218.1  E8X9V9  217 aa molecular chaperone 2.3e-7 ●●○○○ -1.45 -1.44668804669206
Acinetobacter baumannii ATCC 17978  A1S_2016  ABO12443.2  169 aa Phage-related lysozyme 0.024 ●●○○○ -1.45 -1.44668422122866
Escherichia coli M12  CO715_10460  ATI06082.1  391 aa mannose-6-phosphate isomerase 7.3e-9 ●●○○○ -1.45 -1.44645230555864
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2152  AIK80757.1  784 aa ATP-dependent protease La 2.2e-16 ●●○○○ -1.45 -1.44639893989232
Mycobacterium avium subsp. paratuberculosis K10  MAP_2204c  AAS04521.1  Q73XV4  227 aa hypothetical protein 0.046 ●●○○○ -1.45 -1.44606472553158
Acinetobacter baumannii ATCC 17978  A1S_0358  ABO10818.2  587 aa exonuclease V alpha subunit 0.0043 ●●○○○ -1.45 -1.44605056424122
Escherichia coli M12  CO715_21345  ATI08046.1  341 aa ABC transporter permease 0.00011 ●●○○○ -1.45 -1.44561772150164
Escherichia coli M12  CO715_22795  ATI08304.1  91 aa DUF1435 domain-containing protein 0.00023 ●●○○○ -1.44 -1.44436584541615
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3115  WP_000450462.1  E8X8Q4  sdaC  429 aa HAAAP family serine/threonine permease 9.0e-10 ●●○○○ -1.44 -1.44380630646031
Escherichia coli M12  CO715_12520  ATI06456.1  99 aa hypothetical protein 1.9e-6 ●●○○○ -1.44 -1.44332261534491
Escherichia coli M12  CO715_21770  ATI08125.1  262 aa hydroxyethylthiazole kinase 0.00028 ●●○○○ -1.44 -1.44311396933066
Mycobacterium avium subsp. paratuberculosis K10  MAP_3561  AAS06111.1  Q73U07  328 aa hypothetical protein 0.046 ●●○○○ -1.44 -1.44308176513133
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0476  WP_000817201.1  E8XKP3  ybaX  231 aa 7-cyano-7-deazaguanine synthase QueC 5.2e-18 ●●○○○ -1.44 -1.44298263280401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1843  NP_231477.1  Q9KR04  378 aa cytochrome d ubiquinol oxidase subunit II 5.2e-8 ●●○○○ -1.44 -1.44296323480167
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3565  CBW19659.1  A0A0H3NIU6  281 aa hypothetical carbohydrate kinase 0.0038 ●●○○○ -1.44 -1.44286506439022
Escherichia coli M12  CO715_14595  ATI06832.1  201 aa outer membrane lipoprotein carrier protein LolA 1.7e-7 ●●○○○ -1.44 -1.44269667730216
Escherichia coli M12  CO715_00575  ATI04361.1  96 aa transcriptional regulator 0.011 ●●○○○ -1.44 -1.44248803128791
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1119  WP_001018467.1  E8XE83  putP  502 aa sodium/proline symporter PutP 0.014 ●●○○○ -1.44 -1.44240642611513
Escherichia coli M12  CO715_17130  ATI07288.1  475 aa sulfate adenylyltransferase 5.4e-10 ●●○○○ -1.44 -1.44227938527366
Escherichia coli M12  CO715_11400  ATI06257.1  148 aa DUF441 family protein 4.5e-9 ●●○○○ -1.44 -1.44102750918817
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0859  WP_001089314.1  E8XBU6  ybiP  526 aa phosphoethanolamine transferase 9.2e-6 ●●○○○ -1.44 -1.44081474778283
Escherichia coli M12  CO715_00660  ATI04374.1  107 aa transcriptional regulator 3.8e-8 ●●○○○ -1.44 -1.44040157114542
Escherichia coli M12  CO715_07175  ATI05517.1  486 aa two-component system sensor histidine kinase PhoQ 6.9e-19 ●●○○○ -1.44 -1.43998427911692
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0944  NP_230591.1  Q9KTF8  lipB  219 aa lipoate-protein ligase B 5.1e-8 ●●○○○ -1.44 -1.43939183266141
Mycobacterium avium subsp. paratuberculosis K10  MAP_3952  AAS06502.1  Q73SX1  507 aa hypothetical protein 0.046 ●●○○○ -1.44 -1.43927629441232
Mycobacterium avium subsp. paratuberculosis K10  MAP_3764c  AAS06314.1  Q73TF4  pks2  2098 aa Pks2 0.046 ●●○○○ -1.44 -1.43923741399312
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2037  NP_231671.1  Q9KQG1  481 aa Na+/H+ antiporter 5.5e-8 ●●○○○ -1.44 -1.43917099245279
Escherichia coli M12  CO715_05835  ATI05285.1  232 aa phage minor tail protein L 2.1e-21 ●●○○○ -1.44 -1.43894104904568
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0680  WP_000368034.1  E8XA18  hscC  559 aa molecular chaperone HscC 3.7e-10 ●●○○○ -1.44 -1.43891614458261
Mycobacterium avium subsp. paratuberculosis K10  MAP_2104  AAS04421.1  Q73Y53  fdhF  1411 aa FdhF 0.046 ●●○○○ -1.44 -1.43888401467283
Escherichia coli M12  CO715_21695  ATI08111.1  101 aa hypothetical protein 8.3e-10 ●●○○○ -1.44 -1.43873240303143
Escherichia coli M12  CO715_24700  ATI08626.1  258 aa transcriptional regulator LldR 1.3e-8 ●●○○○ -1.44 -1.43873240303143
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3943  AIK82491.1  122 aa hypothetical protein <1e-323 ●●○○○ -1.44 -1.43867071549681
Porphyromonas gingivalis ATCC 33277  PGN_1747  WP_012458503.1  B2RLM1  431 aa hypothetical protein 2.3e-9 ●●○○○ -1.44 -1.43823127840982
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0295  WP_000976553.1  E8XIU8  257 aa membrane protein 3.7e-6 ●●○○○ -1.44 -1.4377993172462
Escherichia coli M12  CO715_03330  ATI04852.1  56 aa hypothetical protein 1.2e-8 ●●○○○ -1.44 -1.43706323491744
Escherichia coli M12  CO715_04510  ATI05065.1  267 aa thioesterase 4.4e-79 ●●○○○ -1.44 -1.43685458890319
Escherichia coli M12  CO715_13400  ATI06617.1  367 aa amino acid ABC transporter permease 6.8e-41 ●●○○○ -1.44 -1.43685458890319
Escherichia coli M12  CO715_21190  ATI08020.1  562 aa DUF2138 domain-containing protein 6.1e-18 ●●○○○ -1.44 -1.43643729687469
Escherichia coli M12  CO715_17035  ATI07269.1  155 aa transporter 8.6e-9 ●●○○○ -1.44 -1.43622865086044
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4818  AIK83345.1  257 aa hisP 0.0074 ●●○○○ -1.44 -1.43614688089645
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2486  WP_001195800.1  E8XF42  sixA  161 aa phosphohistidine phosphatase SixA 0.0044 ●●○○○ -1.44 -1.43611802596541
Escherichia coli M12  CO715_06870  ATI05461.1  134 aa hypothetical protein 2.7e-29 ●●○○○ -1.44 -1.43581135883195
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0505  WP_000467098.1  E8X871  ybaB  109 aa YbaB/EbfC family nucleoid-associated protein 0.015 ●●○○○ -1.44 -1.43577618133692
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4131  WP_001738611.1  E8XJE2  yigG  152 aa membrane protein 1.1e-9 ●●○○○ -1.44 -1.43530970948408
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2964  AIK81549.1  92 aa phnA family protein 1.1e-6 ●●○○○ -1.44 -1.43529236239746
Escherichia coli M12  CO715_10710  ATI06127.1  341 aa PurR family transcriptional regulator 7.8e-6 ●●○○○ -1.44 -1.4351854207892
Escherichia coli M12  CO715_10615  ATI06110.1  155 aa hypothetical protein 9.5e-91 ●●○○○ -1.43 -1.43455948274645
Escherichia coli M12  CO715_00770  ATI04395.1  115 aa hypothetical protein 3.0e-25 ●●○○○ -1.43 -1.43455948274645
Escherichia coli M12  CO715_07410  ATI08757.1  717 aa TIGR01666 family membrane protein 8.8e-5 ●●○○○ -1.43 -1.43455948274645
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1609  AIK80229.1  87 aa glutaredoxin, GrxA family 0.0013 ●●○○○ -1.43 -1.43365654117661
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4771  WP_001111692.1  E8XD99  yjji  515 aa YjjI family glycine radical enzyme 1.3e-9 ●●○○○ -1.43 -1.43358448729366
Escherichia coli M12  CO715_11345  ATI06246.1  137 aa peptide-methionine (R)-S-oxide reductase 1.9e-8 ●●○○○ -1.43 -1.43351625267521
Retrieved entries 2,901–3,000 out of 36,363 total in 1049 ms (Link to these results)