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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_12470  ATI06448.1  183 aa YgjV family protein 7.2e-5 ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_03410  ATI04867.1  183 aa endonuclease SmrB 3.3e-5 ●●○○○ -1.1 -1.09780481574879
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3782  AIK82337.1  137 aa large conductance mechanosensitive channel protein 4.0e-6 ●●○○○ -1.1 -1.09774396595102
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1200  WP_000475705.1  E8XEX1  ptgcb  477 aa PTS glucose transporter subunit IIBC 0.028 ●●○○○ -1.1 -1.0970179602034
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0668  NP_230317.1  Q9KU56  mutH  221 aa DNA mismatch repair protein 1.6e-6 ●●○○○ -1.1 -1.09646606621254
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1521  NP_231161.1  Q9KRW3  677 aa sensor histidine kinase 8.4e-5 ●●○○○ -1.1 -1.09620280860858
Escherichia coli M12  CO715_04680  ATI05092.1  80 aa DsrB protein 0.00023 ●●○○○ -1.1 -1.0961356476348
Escherichia coli M12  CO715_08795  ATI05803.1  225 aa PKHD-type hydroxylase 4.5e-5 ●●○○○ -1.1 -1.0957183556063
Escherichia coli M12  CO715_02345  ATI04674.1  402 aa O-antigen ligase RfaL 6.0e-33 ●●○○○ -1.1 -1.09550970959205
Escherichia coli M12  CO715_12065  ATI06378.1  254 aa glc operon transcriptional activator 4.4e-7 ●●○○○ -1.09 -1.09446647952081
Escherichia coli M12  CO715_12415  ATI06438.1  672 aa NADPH-dependent 2,4-dienoyl-CoA reductase 6.0e-36 ●●○○○ -1.09 -1.09404918749231
Escherichia coli M12  CO715_18020  ATI07448.1  441 aa Xaa-Pro aminopeptidase 1.2e-5 ●●○○○ -1.09 -1.09404918749231
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2089  NP_231721.1  Q9KQB1  588 aa succinate dehydrogenase flavoprotein subunit 9.4e-8 ●●○○○ -1.09 -1.09271721646545
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3861  WP_000665687.1  E8XG03  yibl  120 aa YibL family ribosome-associated protein 9.7e-7 ●●○○○ -1.09 -1.09234284759089
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3070  AIK81655.1  266 aa manY <1e-323 ●●○○○ -1.09 -1.09056872132086
Escherichia coli M12  CO715_21225  ATI08025.1  200 aa cytochrome c-type protein NapC 4.1e-37 ●●○○○ -1.09 -1.09050220525008
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0290  NP_229945.1  P64127  fis  98 aa Fis family transcriptional regulator 6.1e-6 ●●○○○ -1.09 -1.08992507946972
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1922  NP_231556.1  Q9KQS6  clpP  200 aa ATP-dependent Clp protease proteolytic subunit 3.2e-8 ●●○○○ -1.09 -1.08978732311113
Escherichia coli M12  CO715_10350  ATI06063.1  297 aa LysR family transcriptional regulator 3.5e-23 ●●○○○ -1.09 -1.08945897517884
Escherichia coli M12  CO715_17230  ATI07306.1  286 aa electron transfer flavoprotein subunit alpha/FixB family protein 0.0019 ●●○○○ -1.09 -1.08883303713609
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5171  AIK83692.1  510 aa phage Terminase family protein 7.9e-12 ●●○○○ -1.09 -1.08865230870694
Escherichia coli M12  CO715_09195  ATI05871.1  140 aa hypothetical protein 2.7e-16 ●●○○○ -1.09 -1.08841574510759
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2708  NP_232335.2  Q9KNM4  gmk  207 aa guanylate kinase 4.3e-7 ●●○○○ -1.09 -1.08816587571886
Escherichia coli M12  CO715_12335  ATI06425.1  168 aa mismatch-specific DNA-glycosylase 8.1e-6 ●●○○○ -1.09 -1.0875811610506
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1098  NP_230743.1  Q9KT07  ackA1  398 aa acetate kinase 2.7e-10 ●●○○○ -1.09 -1.08743970691971
Escherichia coli M12  CO715_00080  ATI04271.1  427 aa peptidase B 2.1e-109 ●●○○○ -1.09 -1.08737251503635
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1957  WP_000605987.1  E8XA72  flhC  194 aa flagellar transcriptional regulator FlhC 8.0e-5 ●●○○○ -1.09 -1.08709621718212
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0468  WP_001198406.1  E8XKN5  tig  432 aa trigger factor 0.037 ●●○○○ -1.09 -1.08692083992653
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4360  AIK82903.1  215 aa L-fuculose phosphate aldolase 0.00053 ●●○○○ -1.09 -1.08537812247002
Acinetobacter baumannii ATCC 17978  A1S_1779  ABO12206.2  255 aa putative MutT/nudix family protein 3.4e-11 ●●○○○ -1.09 -1.08530451780308
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4801  WP_000482239.1  E8XDC9  181 aa fimbrial protein SthA 0.0065 ●●○○○ -1.08 -1.08475258151807
Escherichia coli M12  CO715_01355  ATI04498.1  426 aa GTPase HflX 8.4e-77 ●●○○○ -1.08 -1.08466011685111
Escherichia coli CFT073  c1681  AAN80148.1  P0AF29  narL  238 aa Nitrate/nitrite response regulator protein narL 0.039 ●●○○○ -1.08 -1.08425452854305
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0070  NP_232471.2  Q9KN95  273 aa phosphate ABC transporter substrate-binding protein 7.4e-8 ●●○○○ -1.08 -1.08367956897888
Escherichia coli M12  CO715_06760  ATI05442.1  122 aa hypothetical protein 5.2e-113 ●●○○○ -1.08 -1.08278230272287
Escherichia coli M12  CO715_03535  ATI04891.1  238 aa amino acid ABC transporter permease 2.3e-18 ●●○○○ -1.08 -1.07986125852339
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3339  AIK81896.1  53 aa hypothetical protein 9.0e-6 ●●○○○ -1.08 -1.07968710138191
Escherichia coli M12  CO715_19990  ATI07799.1  192 aa hypothetical protein 5.1e-13 ●●○○○ -1.08 -1.07881802845215
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3870  AIK82420.1  328 aa putative isomerase <1e-323 ●●○○○ -1.08 -1.07811478605848
Escherichia coli M12  CO715_12980  ATI06540.1  97 aa phospholipid ABC transporter-binding protein 1.3e-35 ●●○○○ -1.08 -1.07798344439515
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1714  AIK80334.1  414 aa cardiolipin synthase 2 6.2e-5 ●●○○○ -1.08 -1.07636313949342
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4413  AIK82956.1  330 aa RNA polymerase sigma factor RpoS 6.8e-14 ●●○○○ -1.08 -1.07631682381031
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3321  WP_001274458.1  E8XB96  ygiq  723 aa YgiQ family radical SAM protein 2.3e-6 ●●○○○ -1.08 -1.07591474283775
Escherichia coli M12  CO715_01770  ATI04569.1  226 aa phosphonate C-P lyase system protein PhnL 3.8e-60 ●●○○○ -1.08 -1.07547969222416
Escherichia coli M12  CO715_13320  ATI06602.1  80 aa hypothetical protein 6.0e-5 ●●○○○ -1.08 -1.07547969222416
Acinetobacter baumannii ATCC 17978  A1S_1615  ABO12042.2  285 aa PAPS (adenosine 3'-phosphate 5'-phosphosulfate) x 0.0015 ●●○○○ -1.07 -1.07464835795819
Escherichia coli M12  CO715_14370  ATI06787.1  98 aa ArsR family transcriptional regulator 2.9e-83 ●●○○○ -1.07 -1.07318458606743
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3554  WP_001273286.1  E8XD97  acrF  1037 aa multidrug efflux RND transporter permease subunit 0.022 ●●○○○ -1.07 -1.07299675132248
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1144  NP_230789.1  Q9KSW2  756 aa ATP-dependent Clp protease ATP-binding subunit 2.9e-6 ●●○○○ -1.07 -1.07183640344307
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2079  AIK80684.1  260 aa hypothetical protein <1e-323 ●●○○○ -1.07 -1.07152830465808
Escherichia coli M12  CO715_08550  ATI05759.1  402 aa MFS transporter 3.8e-81 ●●○○○ -1.07 -1.07151541795344
Escherichia coli M12  CO715_14430  ATI06799.1  489 aa MFS transporter 4.1e-79 ●●○○○ -1.07 -1.07130677193919
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1990  WP_000079805.1  E8XAA1  fliC  495 aa flagellin FliC 0.046 ●●○○○ -1.07 -1.07107553767856
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4574  WP_000118960.1  E8XAQ2  aidB  540 aa isovaleryl-CoA dehydrogenase 7.9e-5 ●●○○○ -1.07 -1.07101151759821
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4195  AIK82740.1  146 aa urease subunit beta <1e-323 ●●○○○ -1.07 -1.07096536851981
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1446  NP_231089.1  Q9KS15  721 aa toxin secretion transporter 2.9e-6 ●●○○○ -1.07 -1.07079097456648
Acinetobacter baumannii ATCC 17978  A1S_0739  ABO11179.1  183 aa putative transcriptional regulator 1.2e-9 ●●○○○ -1.07 -1.07068531008267
Escherichia coli M12  CO715_11115  ATI06203.1  116 aa PTS N N'-diacetylchitobiose transporter subunit IIA 3.9e-11 ●●○○○ -1.07 -1.07047218788219
Escherichia coli M12  CO715_04505  ATI05064.1  525 aa (2,3-dihydroxybenzoyl)adenylate synthase 6.4e-13 ●●○○○ -1.07 -1.07005489585369
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1933  AIK80539.1  402 aa enterochelin esterase <1e-323 ●●○○○ -1.07 -1.06974960138807
Porphyromonas gingivalis ATCC 33277  PGN_0787  WP_005875043.1  B2RIW1  215 aa hypothetical protein 0.03 ●●○○○ -1.07 -1.06971324934085
Escherichia coli M12  CO715_02500  ATI04703.1  569 aa AsmA family protein 4.5e-7 ●●○○○ -1.07 -1.0696376038252
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3262  AIK81823.1  281 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●●○○○ -1.07 -1.06957410474837
Porphyromonas gingivalis ATCC 33277  PGN_0673  WP_010956094.1  B2RIJ7  139 aa biopolymer transporter ExbD <1e-323 ●●○○○ -1.07 -1.06936604113372
Escherichia coli M12  CO715_08555  ATI05760.1  271 aa Cof-type HAD-IIB family hydrolase 5.1e-78 ●●○○○ -1.07 -1.0688030197682
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0039  NP_232440.1  Q9KNC6  140 aa hypothetical protein 4.4e-5 ●●○○○ -1.07 -1.06794783598738
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0305  CBW16406.1  A0A0H3NHU2  fadE  814 aa possible acyl-CoA dehydrogenase 0.048 ●●○○○ -1.07 -1.06740604560045
Acinetobacter baumannii ATCC 17978  A1S_2262  ABO12685.2  288 aa EsvH 0.04 ●●○○○ -1.07 -1.0668466681738
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2754  AIK81344.1  105 aa smpA / OmlA family protein <1e-323 ●●○○○ -1.07 -1.06661919627562
Escherichia coli M12  CO715_22320  ATI08226.1  239 aa LysR family transcriptional regulator 0.0075 ●●○○○ -1.07 -1.06629926759721
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3573  AIK82128.1  59 aa hypothetical protein 1.8e-5 ●●○○○ -1.07 -1.0657358621992
Escherichia coli M12  CO715_02305  ATI04666.1  319 aa hypothetical protein 2.6e-94 ●●○○○ -1.07 -1.06546468354022
Escherichia coli M12  CO715_11235  ATI06225.1  435 aa sulfurtransferase 4.8e-11 ●●○○○ -1.07 -1.06525603752597
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4201  AIK82746.1  388 aa emrA Membrane Fusion Protein <1e-323 ●●○○○ -1.06 -1.06477427169298
Porphyromonas gingivalis ATCC 33277  PGN_0597  WP_012457632.1  B2RIC1  traK  207 aa conjugative transposon protein TraK 3.8e-8 ●●○○○ -1.06 -1.06470442750931
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2319  NP_231950.1  Q9KPP7  recD  706 aa exodeoxyribonuclease V 8.1e-5 ●●○○○ -1.06 -1.06415197721126
Escherichia coli M12  CO715_02835  ATI04766.1  159 aa ethanolamine utilization acetate kinase EutP 8.9e-32 ●●○○○ -1.06 -1.06337822339773
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4556  AIK83094.1  266 aa putative oxalate/formate antiporter 1.7e-15 ●●○○○ -1.06 -1.06241164508471
Escherichia coli M12  CO715_17465  ATI07348.1  417 aa N-acetylmuramoyl-L-alanine amidase 8.1e-14 ●●○○○ -1.06 -1.06233499332649
Acinetobacter baumannii ATCC 17978  A1S_0354  ABO10814.1  911 aa exonuclease V gamma chain 0.0022 ●●○○○ -1.06 -1.06225079695354
Escherichia coli M12  CO715_10980  ATI06176.1  154 aa lipoprotein 1.9e-20 ●●○○○ -1.06 -1.06191770129799
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0168  NP_229825.1  Q9KVH8  135 aa cytochrome c5 6.0e-9 ●●○○○ -1.06 -1.06156909618706
Escherichia coli M12  CO715_08015  ATI05661.1  419 aa DUF1116 domain-containing protein 2.8e-9 ●●○○○ -1.06 -1.06129176325524
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2765  AIK81355.1  415 aa integrase <1e-323 ●●○○○ -1.06 -1.06063190807365
Escherichia coli M12  CO715_01985  ATI04609.1  180 aa hypothetical protein 3.2e-30 ●●○○○ -1.06 -1.060248533184
Escherichia coli M12  CO715_14690  ATI06849.1  208 aa lysoplasmalogenase 7.2e-8 ●●○○○ -1.06 -1.06003988716975
Escherichia coli M12  CO715_21230  ATI08026.1  207 aa cytochrome c biogenesis ATP-binding export protein CcmA 1.2e-5 ●●○○○ -1.06 -1.06003988716975
Porphyromonas gingivalis ATCC 33277  PGN_0230  WP_012457349.1  B2RHA4  144 aa serine O-acetyltransferase <1e-323 ●●○○○ -1.06 -1.06001644040995
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1401  AIK80025.1  67 aa hypothetical protein 0.044 ●●○○○ -1.06 -1.05994770516475
Escherichia coli M12  CO715_20645  ATI07920.1  245 aa phosphatase 0.0004 ●●○○○ -1.06 -1.0598312411555
Escherichia coli M12  CO715_10580  ATI06104.1  500 aa MFS transporter 0.011 ●●○○○ -1.06 -1.0598312411555
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1695  WP_000084401.1  E8XK11  tpx  168 aa thiol peroxidase 1.9e-6 ●●○○○ -1.06 -1.05951655944097
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4676  WP_010989098.1  E8XBN1  39 aa hypothetical protein 0.03 ●●○○○ -1.06 -1.0594566549298
Escherichia coli M12  CO715_16060  ATI07092.1  409 aa polysaccharide deacetylase family protein 5.9e-58 ●●○○○ -1.06 -1.05920530311275
Escherichia coli M12  CO715_17170  ATI07295.1  178 aa type I-E CRISPR-associated protein Cse2/CasB 4.0e-24 ●●○○○ -1.06 -1.05857936507001
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0119  WP_000082819.1  E8XH24  leuA  523 aa 2-isopropylmalate synthase 0.035 ●●○○○ -1.06 -1.05827092335807
Escherichia coli M12  CO715_25160  ATI08678.1  216 aa transposase 1.6e-69 ●●○○○ -1.06 -1.05774478101301
Escherichia coli M12  CO715_09630  ATI05944.1  483 aa molecular chaperone DnaJ 2.2e-21 ●●○○○ -1.06 -1.05732748898451
Escherichia coli M12  CO715_20045  ATI07810.1  482 aa tRNA 4-thiouridine(8) synthase ThiI 2.3e-18 ●●○○○ -1.06 -1.05691019695601
Acinetobacter baumannii ATCC 17978  A1S_1991  ABO12418.1  103 aa putative sulfite reductase 0.0054 ●●○○○ -1.06 -1.05659715232217
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