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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2302  AIK80906.1  331 aa D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein <1e-323 ○○○○○ 0.01 0.0149184160865329
Escherichia coli M12  CO715_18785  ATI07581.1  172 aa hypothetical protein 2.6e-9 ○○○○○ 0.02 0.0153216702688832
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0754  NP_230403.1  Q9KTX6  64 aa hypothetical protein 0.034 ○○○○○ 0.02 0.0153284854291666
Escherichia coli M12  CO715_04615  ATI05081.1  397 aa porin OmpC 1.8e-23 ○○○○○ 0.02 0.015530316283132
Escherichia coli M12  CO715_03975  ATI04972.1  412 aa DNA transporter HofQ 0.02 ○○○○○ 0.02 0.015738962297381
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1051  NP_230696.1  Q9KT54  43 aa hypothetical protein 0.00016 ○○○○○ 0.02 0.016313648340141
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3620  AIK82175.1  522 aa nickel ABC transporter, nickel/metallophore periplasmic binding protein <1e-323 ○○○○○ 0.02 0.0171555429273213
Escherichia coli M12  CO715_06015  ATI05311.1  395 aa MFS transporter 3.5e-17 ○○○○○ 0.02 0.0171994843971229
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0784  NP_230433.1  Q9KTV3  516 aa sodium/alanine symporter 0.017 ○○○○○ 0.02 0.0172579705526171
Escherichia coli M12  CO715_24280  ATI08553.1  261 aa hypothetical protein 9.4e-25 ○○○○○ 0.02 0.0178254224398695
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2544  NP_232172.1  Q9KP35  fbp  336 aa fructose-1,6-bisphosphatase 0.023 ○○○○○ 0.02 0.0182128693787547
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0935  NP_230582.1  Q9KTG7  398 aa hypothetical protein 0.0012 ○○○○○ 0.02 0.0182763321821503
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2353  NP_231983.1  Q9KPL4  283 aa hypothetical protein 0.03 ○○○○○ 0.02 0.0184988862954441
Escherichia coli M12  CO715_01500  ATI04522.1  289 aa hypothetical protein 4.0e-11 ○○○○○ 0.02 0.018660006496865
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3989  AIK82537.1  1080 aa evgS-Phis 1.4e-5 ○○○○○ 0.02 0.0191571976325564
Escherichia coli M12  CO715_17930  ATI07431.1  182 aa isopentenyl-diphosphate Delta-isomerase 6.9e-19 ○○○○○ 0.02 0.0192859445396116
Escherichia coli M12  CO715_13895  ATI06703.1  494 aa hypothetical protein 2.8e-23 ○○○○○ 0.02 0.0197032365681093
Escherichia coli M12  CO715_05135  ATI05168.1  468 aa flagellar filament capping protein FliD 0.035 ○○○○○ 0.02 0.0199118825823582
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0165  NP_229822.1  Q9KVI1  368 aa hypothetical protein 0.0008 ○○○○○ 0.02 0.0201368830973546
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3951  AIK82499.1  415 aa sstT transporter 0.0039 ○○○○○ 0.02 0.0204206582867704
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4106  AIK82652.1  632 aa arginine decarboxylase 4.9e-7 ○○○○○ 0.02 0.0205652473065214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2822  AIK81411.1  636 aa PRD domain protein <1e-323 ○○○○○ 0.02 0.020565268557225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2752  AIK81342.1  419 aa relaxase/mobilization nuclease domain protein 1.3e-9 ○○○○○ 0.02 0.0206099473271712
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1778  NP_231413.1  Q9KR65  siaQ  173 aa hypothetical protein 0.00095 ○○○○○ 0.02 0.0208262153864987
Escherichia coli CFT073  c2721  AAN81175.1  A0A0H2V8W2  yejH  586 aa Hypothetical protein yejH 8.8e-12 ○○○○○ 0.02 0.0208670987538749
Escherichia coli M12  CO715_00855  ATI04410.1  292 aa 2-oxo-3-deoxygalactonate kinase 1.6e-8 ○○○○○ 0.02 0.0215810506963491
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0612  NP_233001.1  Q9KLX9  mscL  136 aa large-conductance mechanosensitive channel 0.004 ○○○○○ 0.02 0.0216847357706947
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1282  NP_230927.1  Q9KSH4  446 aa PTS system cellobiose-specific transporter subunit IIC 0.0087 ○○○○○ 0.02 0.0223923181309746
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4918  AIK83444.1  190 aa elongation factor P (EF-P) OB domain protein 1.9e-5 ○○○○○ 0.02 0.022762785928272
Escherichia coli M12  CO715_11315  ATI06240.1  315 aa sugar kinase 9.9e-6 ○○○○○ 0.02 0.0230415727960911
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1984  NP_231618.1  Q9KQL4  rnd  381 aa ribonuclease D 0.0083 ○○○○○ 0.02 0.0230928659243549
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0651  NP_230300.2  Q9KU72  292 aa hypothetical protein 0.023 ○○○○○ 0.02 0.0235730133178573
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2320  AIK80924.1  286 aa glycerophosphoryl diester phosphodiesterase family protein 0.00027 ○○○○○ 0.02 0.0238732867223565
Escherichia coli M12  CO715_08370  ATI05725.1  299 aa hypothetical protein 4.4e-20 ○○○○○ 0.03 0.0257539709813262
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1899  NP_231533.1  Q9KQU9  383 aa hypothetical protein 0.003 ○○○○○ 0.03 0.0258863708889816
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2986  AIK81571.1  559 aa formate dehydrogenase, alpha subunit <1e-323 ○○○○○ 0.03 0.0259121869027017
Escherichia coli M12  CO715_16520  ATI07178.1  256 aa protein FixA 9.2e-6 ○○○○○ 0.03 0.0259626169955752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1856  AIK80462.1  597 aa filamentous hemagglutinin family N-terminal domain protein 1.3e-7 ○○○○○ 0.03 0.0260020593133122
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0188  NP_229845.1  Q9KVF8  680 aa oligopeptidase A 0.013 ○○○○○ 0.03 0.026508058373222
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2773  NP_232399.1  Q9KNG6  257 aa ParA family protein 0.00024 ○○○○○ 0.03 0.0265096227685513
Escherichia coli M12  CO715_17835  ATI07413.1  398 aa PLP-dependent lyase/thiolase 0.04 ○○○○○ 0.03 0.0265885550383217
Porphyromonas gingivalis ATCC 33277  PGN_0152  WP_012457283.1  B2RH26  540 aa T9SS type A sorting domain-containing protein 2.7e-7 ○○○○○ 0.03 0.0270092308923383
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1311  NP_230955.1  Q9KSE6  292 aa hypothetical protein 0.005 ○○○○○ 0.03 0.0272008312825639
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0214  NP_232613.1  Q9KMV4  414 aa multidrug resistance protein D 0.0012 ○○○○○ 0.03 0.0272024682406186
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4058  AIK82605.1  569 aa CHAP domain protein 0.00021 ○○○○○ 0.03 0.0273790396200958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2827  AIK81416.1  214 aa hypothetical protein 0.021 ○○○○○ 0.03 0.0289118961751552
Escherichia coli M12  CO715_12565  ATI06465.1  443 aa transporter 6.8e-16 ○○○○○ 0.03 0.0295095992378058
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4367  AIK82910.1  468 aa FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family protein <1e-323 ○○○○○ 0.03 0.0296819277836087
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4317  AIK82862.1  610 aa glycerol dehydratase large subunit 4.1e-12 ○○○○○ 0.03 0.0299921504636413
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0990  NP_230636.1  Q9KTB3  rfaH  165 aa transcriptional activator RfaH 0.0015 ○○○○○ 0.03 0.0300728140693016
Escherichia coli M12  CO715_10510  ATI06092.1  333 aa adenosine deaminase 4.1e-7 ○○○○○ 0.03 0.0303441832948012
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3509  AIK82065.1  377 aa 2-amino-3-ketobutyrate coenzyme A ligase <1e-323 ○○○○○ 0.03 0.0304826691957604
Escherichia coli M12  CO715_13440  ATI06622.1  442 aa IS4 family transposase 0.00036 ○○○○○ 0.03 0.0307614753232989
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1031  NP_230676.1  Q9KT74  146 aa inosine monophosphate dehydrogenase-like protein 0.025 ○○○○○ 0.03 0.0308359781628946
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2620  NP_232248.1  Q9KNW0  rimO  470 aa ribosomal protein S12 methylthiotransferase 0.013 ○○○○○ 0.03 0.0316334858337698
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2141  NP_231772.1  P0C6D4  flaG  153 aa flagellar protein FlaG 3.0e-7 ○○○○○ 0.03 0.0317069707087839
Escherichia coli M12  CO715_22655  ATI08897.1  170 aa non-canonical purine NTP phosphatase 0.048 ○○○○○ 0.03 0.0318047053945433
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1619  NP_231259.1  Q9KRL7  182 aa hypothetical protein 0.0068 ○○○○○ 0.03 0.0320352062776444
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1501  NP_231142.1  Q9KRY2  879 aa hypothetical protein 0.0025 ○○○○○ 0.03 0.0320452231911624
Porphyromonas gingivalis ATCC 33277  PGN_0084  WP_012457228.1  B2RGV8  709 aa type IA DNA topoisomerase 5.7e-7 ○○○○○ 0.03 0.03280370171211
Escherichia coli M12  CO715_21525  ATI08081.1  506 aa galactose/methyl galactoside ABC transporter ATP-binding protein MglA 2.3e-38 ○○○○○ 0.03 0.0330565814800364
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0172  NP_229829.1  Q9KVH4  342 aa peptide ABC transporter permease 0.0015 ○○○○○ 0.03 0.0332781388848387
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1143  AIK79766.1  437 aa 6-phospho-beta-glucosidase 4.1e-6 ○○○○○ 0.03 0.0335812896269697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2897  AIK81486.1  451 aa N-acetylmuramoyl-L-alanine amidase 2 0.031 ○○○○○ 0.03 0.0336273181959463
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1668  NP_231304.1  Q9KRH4  235 aa pseudouridine synthase 0.00022 ○○○○○ 0.03 0.033689187874189
Porphyromonas gingivalis ATCC 33277  PGN_0429  WP_012457500.1  B2RHV3  658 aa 4-alpha-glucanotransferase 8.4e-10 ○○○○○ 0.03 0.0342548048104779
Porphyromonas gingivalis ATCC 33277  PGN_0410  WP_012457490.1  B2RHT4  324 aa RNA pseudouridine synthase 3.0e-6 ○○○○○ 0.03 0.0342548048104779
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4532  AIK83070.1  820 aa type VII secretion system (T7SS), usher family protein 1.1e-16 ○○○○○ 0.03 0.034264012523425
Escherichia coli M12  CO715_22025  ATI08173.1  478 aa mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2.0e-7 ○○○○○ 0.03 0.0345171035797785
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1295  NP_230940.1  Q9KSG1  492 aa hypothetical protein 0.032 ○○○○○ 0.04 0.0352788500984868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3287  AIK81848.1  74 aa ribbon-helix-helix, copG family protein <1e-323 ○○○○○ 0.04 0.0354367920507614
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4710  AIK83244.1  198 aa nudix-type nucleoside diphosphatase, YffH/AdpP family protein 1.4e-6 ○○○○○ 0.04 0.0356813814480411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3979  AIK82527.1  387 aa 1,3-propanediol oxidoreductase 6.4e-11 ○○○○○ 0.04 0.0361775515778353
Escherichia coli M12  CO715_17390  ATI07336.1  438 aa L-fucose-proton symporter 6.8e-13 ○○○○○ 0.04 0.0361862716937693
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2749  NP_232375.1  Q9KNI9  ntrC  468 aa nitrogen regulation protein NR(I) 0.013 ○○○○○ 0.04 0.0362350766024347
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4093  AIK82639.1  233 aa alanine racemase, N-terminal domain protein 6.7e-8 ○○○○○ 0.04 0.0362774747844053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3588  AIK82143.1  368 aa endo-1,4-D-glucanase <1e-323 ○○○○○ 0.04 0.0364433184850646
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5074  AIK83600.1  367 aa hypothetical protein 3.2e-10 ○○○○○ 0.04 0.0367580801769303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3656  AIK82211.1  64 aa death on curing protein <1e-323 ○○○○○ 0.04 0.0385892886396127
Escherichia coli M12  CO715_02595  ATI04720.1  63 aa DUF2633 domain-containing protein 3.0e-9 ○○○○○ 0.04 0.0386900238647557
Porphyromonas gingivalis ATCC 33277  PGN_1308  WP_012458170.1  B2RKD2  310 aa DNA-binding protein 1.5e-9 ○○○○○ 0.04 0.0389770744653867
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0552  NP_232942.1  Q9KM37  766 aa fatty acid cis/trans isomerase 0.035 ○○○○○ 0.04 0.0395612560465419
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0941  NP_233325.1  Q9KL09  162 aa acyl-CoA thioesterase 0.029 ○○○○○ 0.04 0.0398619749554819
Escherichia coli M12  CO715_21165  ATI08016.1  761 aa ribonucleoside-diphosphate reductase subunit alpha 0.002 ○○○○○ 0.04 0.0401505459644977
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0090  NP_232491.1  Q9KN75  297 aa hypothetical protein 0.0018 ○○○○○ 0.04 0.0404524111210703
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0192  NP_229849.1  Q9KVF4  270 aa AraC family transcriptional regulator 0.00088 ○○○○○ 0.04 0.0409118022942093
Escherichia coli M12  CO715_15515  ATI06996.1  341 aa transcriptional regulator 0.00044 ○○○○○ 0.04 0.0416110680642397
Escherichia coli M12  CO715_01825  ATI04580.1  488 aa multidrug resistance transporter 1.5e-15 ○○○○○ 0.04 0.0418197140784886
Escherichia coli M12  CO715_17600  ATI07374.1  393 aa acetyl-CoA C-acetyltransferase 0.026 ○○○○○ 0.04 0.0420283600927375
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0442  NP_232836.1  Q9KMC2  158 aa acetyltransferase 0.0033 ○○○○○ 0.04 0.0420948141728056
Escherichia coli M12  CO715_22095  ATI08184.1  506 aa ATP-dependent protease 0.00042 ○○○○○ 0.04 0.0422370061069863
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3561  AIK82116.1  776 aa biotin sulfoxide reductase <1e-323 ○○○○○ 0.04 0.0424721055549143
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4581  AIK83119.1  102 aa stationary phase translation inhibitor and ribosome stability factor 0.00091 ○○○○○ 0.04 0.042552983651679
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0729  NP_233116.1  Q9KLL4  207 aa hypothetical protein 0.041 ○○○○○ 0.04 0.0428601736534025
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0920  NP_233305.1  Q9KL29  199 aa hypothetical protein 0.013 ○○○○○ 0.04 0.0428798287283139
Escherichia coli M12  CO715_13370  ATI06611.1  1034 aa multidrug efflux RND transporter permease subunit 2.1e-27 ○○○○○ 0.04 0.0432802361782306
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2450  NP_232079.2  Q9KPC2  271 aa nucleoside triphosphate pyrophosphohydrolase 0.0015 ○○○○○ 0.04 0.0436477764536956
Escherichia coli M12  CO715_13620  ATI06652.1  332 aa transcriptional regulator 1.2e-18 ○○○○○ 0.05 0.0455753423349681
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3885  AIK82435.1  468 aa D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 8.2e-6 ○○○○○ 0.05 0.0457379375100259
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1627  AIK80247.1  152 aa hypothetical protein 0.0045 ○○○○○ 0.05 0.0459029351083472
Retrieved entries 31,701–31,800 out of 36,363 total in 9 ms (Link to these results)