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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_01830  ATI04581.1  715 aa formate dehydrogenase N subunit alpha, selenocysteine-containing 2.6e-12 ○○○○○ 0.1 0.101909766182161
Escherichia coli M12  CO715_17000  ATI07263.1  153 aa formate hydrogenlyase regulatory protein HycA 0.0083 ○○○○○ 0.1 0.101909766182161
Porphyromonas gingivalis ATCC 33277  PGN_0981  WP_012457933.1  B2RJF5  queA  405 aa S-adenosylmethionine:tRNA ribosyltransferase-isomerase 0.017 ○○○○○ 0.1 0.102066244302492
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0649  NP_230298.1  Q9KU74  139 aa MarR family transcriptional regulator 0.009 ○○○○○ 0.1 0.102345760928293
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2599  NP_232227.1  Q9KNY1  rnr  821 aa ribonuclease R 0.028 ○○○○○ 0.1 0.102853876113006
Escherichia coli M12  CO715_22050  ATI08178.1  406 aa colanic acid biosynthesis glycosyltransferase WcaL 0.013 ○○○○○ 0.1 0.102952996253405
Escherichia coli M12  CO715_14660  ATI06843.1  405 aa MFS transporter 5.7e-8 ○○○○○ 0.1 0.103161642267654
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2254  AIK80859.1  260 aa ABC transporter family protein 8.2e-13 ○○○○○ 0.1 0.103444849519308
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0870  NP_230517.1  Q7DCS6  145 aa IS1004 transposase 3.7e-5 ○○○○○ 0.1 0.10354113823803
Escherichia coli M12  CO715_08650  ATI05777.1  411 aa molybdopterin molybdotransferase 0.021 ○○○○○ 0.1 0.103578934296152
Escherichia coli M12  CO715_21140  ATI08012.1  292 aa transcriptional regulator 9.9e-30 ○○○○○ 0.1 0.104204872338898
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4351  AIK82894.1  76 aa putative lipoprotein 0.0056 ○○○○○ 0.1 0.104664718099285
Escherichia coli M12  CO715_11075  ATI06195.1  196 aa metal-dependent hydrolase 3.1e-8 ○○○○○ 0.11 0.105039456395894
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2508  NP_232137.1  Q9KP68  argF  334 aa ornithine carbamoyltransferase 2.5e-5 ○○○○○ 0.11 0.105560916501485
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1133  NP_230778.1  Q9F854  hisD  431 aa histidinol dehydrogenase 0.0089 ○○○○○ 0.11 0.105594597518641
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2988  AIK81573.1  437 aa proton/sodium-glutamate symport protein 3.3e-16 ○○○○○ 0.11 0.105879151532823
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3239  AIK81800.1  123 aa gamma-carboxymuconolactone decarboxylase 3.1e-11 ○○○○○ 0.11 0.106140810305646
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0819  NP_230467.2  P0C6D7  aldA  479 aa aldehyde dehydrogenase 0.0032 ○○○○○ 0.11 0.107097712693649
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0338  NP_229992.1  Q9KV20  478 aa transporter 0.0032 ○○○○○ 0.11 0.107302649937568
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3792  AIK82348.1  165 aa bacterial transferase hexapeptide family protein <1e-323 ○○○○○ 0.11 0.10779322482492
Escherichia coli M12  CO715_23010  ATI08343.1  257 aa GntR family transcriptional regulator 0.0059 ○○○○○ 0.11 0.107960500595378
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2781  AIK81370.1  285 aa helix-turn-helix domain, rpiR family protein 4.6e-8 ○○○○○ 0.11 0.108094250528229
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4388  AIK82931.1  745 aa relA/SpoT family protein <1e-323 ○○○○○ 0.11 0.108158367283968
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2523  NP_232152.1  Q9KP53  326 aa hypothetical protein 0.046 ○○○○○ 0.11 0.108162068850301
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1970  NP_231604.1  Q9KQM8  387 aa benzoate transport protein 0.00013 ○○○○○ 0.11 0.10831793140832
Escherichia coli M12  CO715_14940  ATI06894.1  472 aa DUF1116 domain-containing protein 9.5e-9 ○○○○○ 0.11 0.109003730666622
Escherichia coli M12  CO715_07545  ATI05581.1  1246 aa nitrate reductase subunit alpha 0.0013 ○○○○○ 0.11 0.109629668709368
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1112  NP_233491.1  Q9KKJ5  tmcA  708 aa hypothetical protein 0.0086 ○○○○○ 0.11 0.10970241025634
Escherichia coli M12  CO715_01370  ATI04501.1  615 aa DNA mismatch repair protein MutL 5.8e-16 ○○○○○ 0.11 0.110046960737866
Escherichia coli M12  CO715_15145  ATI06932.1  195 aa fimbrial protein 9.3e-14 ○○○○○ 0.11 0.110255606752115
Escherichia coli M12  CO715_04145  ATI05005.1  637 aa ABC transporter ATP-binding protein 0.0047 ○○○○○ 0.11 0.110672898780613
Escherichia coli M12  CO715_19500  ATI07712.1  72 aa osmotically-inducible lipoprotein B 7.0e-12 ○○○○○ 0.11 0.111090190809111
Escherichia coli M12  CO715_06955  ATI05475.1  97 aa lipoprotein bor 1.2e-8 ○○○○○ 0.11 0.111298836823359
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0137  NP_229795.2  Q9KVK6  cdgJ  408 aa hypothetical protein 0.01 ○○○○○ 0.11 0.112220308002102
Escherichia coli M12  CO715_18175  ATI07475.1  235 aa energy-coupling factor transporter transmembrane protein EcfT 2.3e-6 ○○○○○ 0.11 0.112342066894604
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1766  NP_231401.1  Q9KR77  663 aa hypothetical protein 0.005 ○○○○○ 0.11 0.112418267355716
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4215  AIK82760.1  109 aa arsR transcriptional regulator 1.3e-8 ○○○○○ 0.11 0.112833761227533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3323  AIK81880.1  482 aa VWA domain containing CoxE-like family protein 9.5e-15 ○○○○○ 0.11 0.113281192047038
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5161  AIK83682.1  326 aa hypothetical protein 0.013 ○○○○○ 0.11 0.113622316982483
Porphyromonas gingivalis ATCC 33277  PGN_0160  WP_012457290.1  B2RH34  thiC  587 aa phosphomethylpyrimidine synthase ThiC 0.00087 ○○○○○ 0.11 0.113851302855674
Porphyromonas gingivalis ATCC 33277  PGN_0160  WP_039416892.1  B2RH34  thiC  66 aa sulfur carrier protein ThiS 0.00087 ○○○○○ 0.11 0.113851302855674
Escherichia coli M12  CO715_15095  ATI06924.1  306 aa alpha/beta hydrolase 5.4e-36 ○○○○○ 0.11 0.114011235008595
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0671  NP_230320.1  Q9KU53  rppH  193 aa dinucleoside polyphosphate hydrolase 0.033 ○○○○○ 0.11 0.114122502908773
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0426  NP_230080.1  Q9KUT9  127 aa hypothetical protein 0.0091 ○○○○○ 0.11 0.114863785623075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3383  AIK81940.1  141 aa putative dNA-binding transcriptional regulator 0.012 ○○○○○ 0.12 0.115431058265171
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5048  AIK83574.1  428 aa putrescine importer 0.00023 ○○○○○ 0.12 0.116770836390111
Escherichia coli M12  CO715_01230  ATI04474.1  228 aa L-ribulose-5-phosphate 4-epimerase UlaF 3.2e-27 ○○○○○ 0.12 0.117140925222327
Escherichia coli M12  CO715_03870  ATI04953.1  773 aa ferrous iron transporter B 0.00035 ○○○○○ 0.12 0.117140925222327
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1992  NP_231626.1  Q9KQK6  purU  277 aa formyltetrahydrofolate deformylase 0.00072 ○○○○○ 0.12 0.117531624975677
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1959  NP_231593.1  Q9KQN9  minC  220 aa septum formation inhibitor 0.019 ○○○○○ 0.12 0.117642927611648
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0065  NP_232466.1  Q9KNA0  768 aa hypothetical protein 0.025 ○○○○○ 0.12 0.11779212524308
Porphyromonas gingivalis ATCC 33277  PGN_0006  WP_012457163.1  B2RGN0  459 aa MATE family efflux transporter 0.0079 ○○○○○ 0.12 0.11780747306261
Escherichia coli M12  CO715_12220  ATI06406.1  388 aa nucleotide sugar dehydrogenase 1.5e-16 ○○○○○ 0.12 0.117975509279323
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2538  AIK81135.1  508 aa citrate lyase, alpha subunit <1e-323 ○○○○○ 0.12 0.117997563137268
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0812  NP_230461.1  Q9KTS6  979 aa helicase-like protein 0.01 ○○○○○ 0.12 0.119458925962618
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2952  AIK81537.1  261 aa DSBA-like thioredoxin domain protein 2.8e-14 ○○○○○ 0.12 0.119592859195229
Escherichia coli M12  CO715_24345  ATI08565.1  141 aa type VI secretion system baseplate subunit TssE 0.00036 ○○○○○ 0.12 0.119644677393314
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3467  AIK82023.1  336 aa fructose-1,6-bisphosphatase, class II <1e-323 ○○○○○ 0.12 0.119929030741525
Escherichia coli M12  CO715_11785  ATI06326.1  104 aa quinol monooxygenase YgiN 0.011 ○○○○○ 0.12 0.120061969421812
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3442  AIK81998.1  317 aa bacterial regulatory helix-turn-helix, AraC family protein 1.1e-5 ○○○○○ 0.12 0.120075183376699
Escherichia coli M12  CO715_16340  ATI07145.1  314 aa transcriptional regulator 2.2e-13 ○○○○○ 0.12 0.12027061543606
Escherichia coli M12  CO715_18210  ATI07481.1  462 aa PTS mannitol transporter subunit IIBC 1.8e-9 ○○○○○ 0.12 0.120479261450309
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4454  AIK82997.1  602 aa NADH-Ubiquinone/plastoquinone (complex I), various chains family protein 3.3e-6 ○○○○○ 0.12 0.121278867501481
Escherichia coli M12  CO715_23355  ATI08394.1  326 aa hypothetical protein 0.03 ○○○○○ 0.12 0.121313845507305
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2400  AIK80997.1  709 aa fhuA outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 <1e-323 ○○○○○ 0.12 0.121345990726841
Escherichia coli M12  CO715_15725  ATI07030.1  398 aa protoheme IX biogenesis protein HemY 2.6e-9 ○○○○○ 0.12 0.121731137535802
Escherichia coli M12  CO715_04480  ATI05059.1  350 aa hypothetical protein 6.4e-9 ○○○○○ 0.12 0.121731137535802
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3577  AIK82132.1  811 aa bacterial cellulose synthase subunit <1e-323 ○○○○○ 0.12 0.121889927103113
Escherichia coli M12  CO715_03375  ATI04860.1  188 aa fimbrial protein 4.8e-60 ○○○○○ 0.12 0.1221484295643
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4631  AIK83166.1  425 aa PRD domain protein <1e-323 ○○○○○ 0.12 0.123292502210116
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4523  AIK83060.1  300 aa aspartyl/Asparaginyl beta-hydroxylase family protein 3.0e-12 ○○○○○ 0.12 0.123327354031799
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3663  AIK82218.1  580 aa gamma-glutamyltransferase <1e-323 ○○○○○ 0.12 0.123555418048675
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3242  AIK81802.1  378 aa hypothetical protein 3.1e-7 ○○○○○ 0.12 0.123876045324046
Escherichia coli M12  CO715_17140  ATI07290.1  345 aa aminopeptidase 0.03 ○○○○○ 0.12 0.12402624369254
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0952  NP_230599.1  Q9KTF0  rsfS  105 aa hypothetical protein 0.012 ○○○○○ 0.12 0.124212699454111
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3718  AIK82273.1  847 aa nitrite reductase, large subunit <1e-323 ○○○○○ 0.12 0.124345749273014
Escherichia coli M12  CO715_17220  ATI07304.1  86 aa ferredoxin family protein 5.0e-12 ○○○○○ 0.12 0.124443535721038
Escherichia coli M12  CO715_08460  ATI05741.1  493 aa sulfatase 0.0015 ○○○○○ 0.12 0.124443535721038
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3449  AIK82005.1  772 aa &alpha-xylosidase <1e-323 ○○○○○ 0.12 0.124614528013114
Escherichia coli M12  CO715_20190  ATI08872.1  394 aa MFS transporter AraJ 3.0e-14 ○○○○○ 0.12 0.124652181735286
Escherichia coli M12  CO715_07805  ATI05623.1  71 aa lysis protein S 5.7e-7 ○○○○○ 0.12 0.124860827749535
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2021  AIK80627.1  392 aa amidohydrolase family protein 9.6e-12 ○○○○○ 0.13 0.125006731016654
Escherichia coli M12  CO715_02775  ATI04756.1  118 aa arsenate reductase 0.0046 ○○○○○ 0.13 0.125278119778033
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2669  NP_232297.1  Q9KNR2  116 aa 5-carboxymethyl-2-hydroxymuconate delta-isomerase 0.033 ○○○○○ 0.13 0.12580262726388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1943  AIK80549.1  316 aa transketolase, pyrimidine binding domain protein 2.2e-16 ○○○○○ 0.13 0.126194204237749
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1414  NP_231057.1  Q9KS46  524 aa thermostable carboxypeptidase 1 0.012 ○○○○○ 0.13 0.126531914315188
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3950  AIK82498.1  184 aa inner membrane protein <1e-323 ○○○○○ 0.13 0.126556732222491
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0193  NP_232593.1  Q9KMX3  447 aa Na+/H+ antiporter 0.029 ○○○○○ 0.13 0.126574254484971
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2655  AIK81249.1  267 aa 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 0.015 ○○○○○ 0.13 0.126956211254089
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4627  AIK83161.1  398 aa ROK family protein 1.1e-9 ○○○○○ 0.13 0.12745932893367
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4580  AIK83117.1  290 aa SMP-30/Gluconolaconase/LRE-like region family protein 0.002 ○○○○○ 0.13 0.127734514486411
Escherichia coli M12  CO715_21755  ATI08122.1  112 aa heavy metal resistance protein 3.8e-9 ○○○○○ 0.13 0.127781871949019
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1659  AIK80279.1  127 aa biofilm formation family protein 2.8e-11 ○○○○○ 0.13 0.127827356550306
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1792  NP_231427.1  Q9KR54  119 aa hypothetical protein 0.014 ○○○○○ 0.13 0.128151913658329
Escherichia coli M12  CO715_00525  ATI04351.1  440 aa xylose isomerase 7.9e-24 ○○○○○ 0.13 0.128407809991766
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4628  AIK83162.1  1065 aa TPR repeat family protein <1e-323 ○○○○○ 0.13 0.128437592347004
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1805  NP_231440.1  Q9KR41  148 aa hypothetical protein 0.043 ○○○○○ 0.13 0.129064435176778
Escherichia coli M12  CO715_16985  ATI07261.1  608 aa formate hydrogenlyase subunit 3 1.5e-11 ○○○○○ 0.13 0.129659686077259
Escherichia coli M12  CO715_08645  ATI05776.1  321 aa beta-aspartyl-peptidase 0.0048 ○○○○○ 0.13 0.130076978105757
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2036  NP_231670.1  Q9KQG2  asd1  370 aa aspartate-semialdehyde dehydrogenase 0.024 ○○○○○ 0.13 0.13015193744643
Retrieved entries 32,001–32,100 out of 36,363 total in 8 ms (Link to these results)