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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_06595  ATI05412.1  210 aa dihydroxyacetone kinase subunit L 0.0085 ●●○○○ -1.59 -1.5902094093761
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2270  NP_231901.1  Q9KPU2  217 aa riboflavin synthase subunit alpha 4.6e-7 ●●○○○ -1.59 -1.5897847078002
Escherichia coli M12  CO715_16910  ATI07248.1  321 aa arabinose-5-phosphate isomerase GutQ 7.9e-11 ●●○○○ -1.59 -1.58958347133336
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3823  CBW19914.1  A0A0H3NHQ6  pstC  319 aa phosphate transport system permease protein 0.016 ●●○○○ -1.59 -1.58952496355035
Escherichia coli M12  CO715_02675  ATI04736.1  137 aa formate hydrogenlyase maturation protein HycH 6.5e-29 ●●○○○ -1.59 -1.58895753329061
Escherichia coli M12  CO715_18425  ATI07521.1  235 aa hypothetical protein 2.2e-14 ●●○○○ -1.59 -1.58895753329061
Mycobacterium avium subsp. paratuberculosis K10  MAP_0673  AAS02990.1  Q743B2  530 aa hypothetical protein 0.037 ●●○○○ -1.59 -1.58862450643924
Escherichia coli M12  CO715_02625  ATI04726.1  345 aa phosphoribosylformylglycinamidine cyclo-ligase 4.6e-39 ●●○○○ -1.59 -1.58791430321937
Acinetobacter baumannii ATCC 17978  A1S_0423  ABO10878.2  A3M1T4  truA  265 aa tRNA-pseudouridine synthase I 1.0e-13 ●●○○○ -1.59 -1.58698724871011
Escherichia coli M12  CO715_09975  ATI08774.1  206 aa enterobactin synthase subunit EntD 2.4e-8 ●●○○○ -1.59 -1.58645378111962
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2420  AIK81017.1  809 aa ATP-dependent helicase HrpB 2.4e-9 ●●○○○ -1.59 -1.58628585819714
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0671  WP_001670689.1  E8XA09  390 aa carbohydrate hydrolase 0.001 ●●○○○ -1.59 -1.5861212297811
Streptococcus pyogenes M1 5448  SP5448_01775  WP_002983122.1  163 aa single-stranded DNA-binding protein 0.029 ●●○○○ -1.59 -1.58542044362788
Escherichia coli M12  CO715_04755  ATI08727.1  104 aa flagellar hook-basal body complex protein FliE 5.7e-54 ●●○○○ -1.59 -1.58520190503413
Escherichia coli M12  CO715_12695  ATI06488.1  144 aa PTS N-acetylgalactosamine transporter subunit IIA 1.9e-52 ●●○○○ -1.58 -1.58478461300563
Acinetobacter baumannii ATCC 17978  A1S_2130  ABO12557.1  1147 aa hypothetical protein 7.5e-11 ●●○○○ -1.58 -1.58476087258263
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3256  AIK81817.1  87 aa LTXXQ motif family protein <1e-323 ●●○○○ -1.58 -1.58463556200493
Escherichia coli M12  CO715_00970  ATI04429.1  445 aa NCS2 family permease 1.1e-9 ●●○○○ -1.58 -1.58311544489164
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3662  AIK82217.1  106 aa hypothetical protein <1e-323 ●●○○○ -1.58 -1.58203182623292
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4415  WP_000790037.1  E8X8Y3  pgi  549 aa glucose-6-phosphate isomerase 0.0013 ●●○○○ -1.58 -1.58194770767952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4550  AIK83088.1  142 aa transcriptional regulator family protein 3.2e-11 ●●○○○ -1.58 -1.5818588205683
Mycobacterium avium subsp. paratuberculosis K10  MAP_0407c  AAS02724.1  Q744D4  acs  650 aa Acs 0.038 ●●○○○ -1.58 -1.57993566477835
Mycobacterium avium subsp. paratuberculosis K10  MAP_1576  AAS03893.1  Q73ZM6  814 aa hypothetical protein 0.038 ●●○○○ -1.58 -1.57932005582618
Escherichia coli M12  CO715_20275  ATI07853.1  364 aa D-alanine--D-alanine ligase 1.5e-9 ●●○○○ -1.58 -1.57873387859242
Escherichia coli M12  CO715_04305  ATI05036.1  158 aa sigma D regulator 3.4e-7 ●●○○○ -1.58 -1.57852523257817
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4087  WP_000024948.1  E8XIM0  ilvC  491 aa ketol-acid reductoisomerase 0.0015 ●●○○○ -1.58 -1.57794797009529
Mycobacterium avium subsp. paratuberculosis K10  MAP_3443  AAS05993.1  Q73UC5  sdhA  584 aa SdhA 0.038 ●●○○○ -1.58 -1.57786599223399
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4781  WP_000209756.1  E8XDA9  lplA  338 aa lipoate--protein ligase LplA 9.7e-11 ●●○○○ -1.58 -1.57727395826816
Escherichia coli M12  CO715_20870  ATI07961.1  401 aa flagellar hook protein FlgE 1.3e-6 ●●○○○ -1.58 -1.57685606446418
Mycobacterium avium subsp. paratuberculosis K10  MAP_3010c  AAS05558.1  Q73VK3  575 aa hypothetical protein 0.038 ●●○○○ -1.58 -1.57666697823433
Escherichia coli M12  CO715_12010  ATI06368.1  252 aa hypothetical protein 1.5e-17 ●●○○○ -1.58 -1.57643877243568
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3865  WP_000636696.1  E8XG07  lldR  258 aa transcriptional regulator LldR 8.1e-11 ●●○○○ -1.58 -1.57614624557585
Acinetobacter baumannii ATCC 17978  A1S_1030  ABO11462.1  516 aa DNA-binding ATP-dependent protease La 4.8e-20 ●●○○○ -1.58 -1.57549502056574
Mycobacterium avium subsp. paratuberculosis K10  MAP_1938c  AAS04255.1  Q73YL7  mmpS3  266 aa MmpS3 0.038 ●●○○○ -1.58 -1.57534145157883
Escherichia coli M12  CO715_05540  ATI05239.1  389 aa transposase 3.3e-9 ●●○○○ -1.57 -1.57497825033594
Escherichia coli M12  CO715_08235  ATI05702.1  208 aa hydrolase 0.00013 ●●○○○ -1.57 -1.57476960432169
Escherichia coli M12  CO715_08990  ATI05840.1  331 aa 6-phosphogluconolactonase 0.00017 ●●○○○ -1.57 -1.57435231229319
Escherichia coli M12  CO715_02940  ATI04784.1  299 aa peroxidase 9.8e-6 ●●○○○ -1.57 -1.57393502026469
Escherichia coli M12  CO715_06910  ATI05468.1  285 aa metal ABC transporter permease 0.00015 ●●○○○ -1.57 -1.5731004362077
Porphyromonas gingivalis ATCC 33277  PGN_1964  WP_012458647.1  B2RM87  706 aa CRISPR-associated helicase/endonuclease Cas3 4.2e-10 ●●○○○ -1.57 -1.57301150703836
Escherichia coli M12  CO715_14860  ATI06880.1  483 aa 2-methylcitrate dehydratase 5.8e-28 ●●○○○ -1.57 -1.5722658521507
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3895  WP_001261577.1  E8XGS1  rfaG  374 aa glycosyltransferase family 1 protein 0.00016 ●●○○○ -1.57 -1.57162348224619
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3896  WP_001526672.1  E8XGS2  rfaQ  356 aa lipopolysaccharide core heptosyltransferase RfaQ 0.00016 ●●○○○ -1.57 -1.57162348224619
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2461  WP_000262102.1  E8XF17  cvpA  162 aa colicin V production protein 0.0018 ●●○○○ -1.57 -1.57135850190908
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4241  CBW20327.1  A0A0H3NPE4  dcuS  543 aa two-component sensor kinase 0.00039 ●●○○○ -1.57 -1.57086204326238
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3824  CBW19915.1  A0A0H3NN94  pstS  346 aa periplasmic phosphate-binding protein 0.0025 ●●○○○ -1.57 -1.57043924413737
Escherichia coli M12  CO715_03770  ATI04935.1  111 aa 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE 0.00032 ●●○○○ -1.57 -1.56871886990847
Escherichia coli M12  CO715_15875  ATI07057.1  753 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 9.5e-80 ●●○○○ -1.57 -1.56851022389422
Escherichia coli M12  CO715_16440  ATI07162.1  219 aa bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA 1.7e-17 ●●○○○ -1.57 -1.56830157787997
Mycobacterium avium subsp. paratuberculosis K10  MAP_1318c  AAS03635.1  Q740N2  443 aa hypothetical protein 0.038 ●●○○○ -1.57 -1.56757149358178
Acinetobacter baumannii ATCC 17978  A1S_0606  ABO11055.1  108 aa hypothetical protein 0.0013 ●●○○○ -1.57 -1.56699161988085
Escherichia coli M12  CO715_22565  ATI08266.1  317 aa transaldolase B 2.6e-6 ●●○○○ -1.57 -1.56684105578023
Escherichia coli M12  CO715_17010  ATI07264.1  290 aa hydrogenase accessory protein HypB 3.1e-6 ●●○○○ -1.57 -1.56684105578023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3069  AIK81654.1  164 aa manX <1e-323 ●●○○○ -1.57 -1.56681988958594
Escherichia coli M12  CO715_22130  ATI08190.1  514 aa threonine ammonia-lyase, biosynthetic 2.9e-9 ●●○○○ -1.57 -1.56663240976598
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4788  WP_014343943.1  E8XDB6  slt  657 aa murein transglycosylase 0.0018 ●●○○○ -1.57 -1.56631709585026
Escherichia coli M12  CO715_01940  ATI04600.1  107 aa regulatory protein SoxS 1.6e-6 ●●○○○ -1.57 -1.56579782570899
Escherichia coli M12  CO715_12575  ATI06467.1  129 aa reactive intermediate/imine deaminase 2.0e-11 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_00180  ATI04289.1  444 aa ATP-dependent RNA helicase SrmB 1.1e-9 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_24760  ATI08636.1  928 aa DNA polymerase I 0.00022 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_11420  ATI06261.1  84 aa hypothetical protein 0.00037 ●●○○○ -1.57 -1.56558917969474
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4504  AIK83042.1  176 aa emrR transcriptional repressor MprA transcriptional repressor <1e-323 ●●○○○ -1.56 -1.56472897180277
Escherichia coli M12  CO715_08285  ATI05711.1  321 aa thioredoxin-disulfide reductase 1.2e-8 ●●○○○ -1.56 -1.56454594962349
Acinetobacter baumannii ATCC 17978  A1S_3335  ABO13724.2  A3M9Y0  murC  482 aa UDP-N-acetylmuramate--alanine ligase 0.0031 ●●○○○ -1.56 -1.56357311987868
Mycobacterium avium subsp. paratuberculosis K10  MAP_2663c  AAS04980.1  Q73WJ7  169 aa hypothetical protein 0.039 ●●○○○ -1.56 -1.56318084829142
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2463  CBW18565.1  A0A0H3NKB8  purN  212 aa phosphoribosylglycinamidine myltransferase 0.0017 ●●○○○ -1.56 -1.56285408046128
Escherichia coli M12  CO715_16365  ATI07149.1  201 aa 3-isopropylmalate dehydratase small subunit 0.00022 ●●○○○ -1.56 -1.56245948948101
Escherichia coli M12  CO715_04890  ATI05127.1  354 aa bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada 1.0e-13 ●●○○○ -1.56 -1.56225084346676
Escherichia coli M12  CO715_02890  ATI04775.1  453 aa ethanolamine ammonia-lyase heavy chain 3.9e-12 ●●○○○ -1.56 -1.56225084346676
Escherichia coli M12  CO715_13900  ATI06704.1  387 aa hypothetical protein 3.3e-7 ●●○○○ -1.56 -1.56183355143826
Mycobacterium avium subsp. paratuberculosis K10  MAP_0949  AAS03266.1  Q741Y8  617 aa hypothetical protein 0.039 ●●○○○ -1.56 -1.56081024478469
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1639  NP_231276.1  Q9KRK1  462 aa sensor histidine kinase 4.1e-9 ●●○○○ -1.56 -1.55984023873352
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3163  AIK81735.1  720 aa DNA helicase II <1e-323 ●●○○○ -1.56 -1.55976481621001
Escherichia coli M12  CO715_04155  ATI05007.1  184 aa glutathione-regulated potassium-efflux system ancillary protein KefG 8.4e-26 ●●○○○ -1.56 -1.55953844528152
Escherichia coli M12  CO715_12835  ATI06516.1  294 aa lipoprotein NlpI 0.007 ●●○○○ -1.56 -1.55807792318178
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0191  CBW16293.1  A0A0H3NCW6  mrcB  840 aa penicillin-binding protein 1b; peptidoglycan synthetase 0.029 ●●○○○ -1.56 -1.558016913705
Escherichia coli M12  CO715_13075  ATI06558.1  778 aa hybrid sensor histidine kinase/response regulator 1.4e-22 ●●○○○ -1.56 -1.55724333912478
Mycobacterium avium subsp. paratuberculosis K10  MAP_3757c  AAS06307.1  Q73TG1  368 aa hypothetical protein 0.039 ●●○○○ -1.56 -1.55532586377658
Mycobacterium avium subsp. paratuberculosis K10  MAP_2173c  AAS04490.1  Q73XY5  mbtE  1759 aa MbtE 0.039 ●●○○○ -1.55 -1.55475161770916
Acinetobacter baumannii ATCC 17978  A1S_2564  ABO12981.1  145 aa putative siderophore-interacting protein 1.5e-8 ●●○○○ -1.55 -1.55475101700725
Acinetobacter baumannii ATCC 17978  A1S_1917  ABO12344.2  254 aa putative potassium uptake protein 2.1e-12 ●●○○○ -1.55 -1.55461013040837
Escherichia coli M12  CO715_00705  ATI04382.1  196 aa DNA-binding response regulator 1.9e-14 ●●○○○ -1.55 -1.5543222949253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4131  AIK82677.1  239 aa hypothetical protein <1e-323 ●●○○○ -1.55 -1.55413483259328
Escherichia coli M12  CO715_17505  ATI07356.1  187 aa prepilin-type cleavage/methylation domain-containing protein 0.0001 ●●○○○ -1.55 -1.55411364891105
Escherichia coli M12  CO715_06670  ATI05425.1  304 aa muramoyltetrapeptide carboxypeptidase 6.2e-7 ●●○○○ -1.55 -1.55369635688255
Escherichia coli M12  CO715_16110  ATI07101.1  264 aa S-adenosylmethionine decarboxylase proenzyme 0.00016 ●●○○○ -1.55 -1.5534877108683
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4196  AIK82741.1  359 aa ammonium Transporter family protein <1e-323 ●●○○○ -1.55 -1.55263800351945
Escherichia coli M12  CO715_10915  ATI06163.1  58 aa hypothetical protein 1.3e-9 ●●○○○ -1.55 -1.55244448079706
Streptococcus pyogenes M1 5448  SP5448_00855  WP_002987876.1  430 aa adenylosuccinate synthase 0.016 ●●○○○ -1.55 -1.55177366619561
Escherichia coli M12  CO715_00330  ATI04318.1  417 aa serine hydroxymethyltransferase 0.036 ●●○○○ -1.55 -1.55098395869732
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0242  NP_232640.1  Q9KMS8  215 aa 3-keto-L-gulonate-6-phosphate decarboxylase 7.3e-7 ●●○○○ -1.55 -1.5507188748489
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3290  AIK81851.1  131 aa D-tyrosyl-tRNA(Tyr) deacylase 4.9e-10 ●●○○○ -1.55 -1.55026281050013
Escherichia coli M12  CO715_08500  ATI05749.1  370 aa spermidine/putrescine ABC transporter substrate-binding protein PotF 0.0077 ●●○○○ -1.55 -1.54973208261183
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2364  WP_000865526.1  E8XEB0  ompC  378 aa porin OmpC 0.0017 ●●○○○ -1.55 -1.54888560338799
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0031  CBW16132.1  A0A0H3N7C1  334 aa hypothetical transcriptional regulator (lysR family) 0.00014 ●●○○○ -1.55 -1.54864452847174
Escherichia coli M12  CO715_20675  ATI07926.1  216 aa transcriptional regulator CsgD 6.1e-35 ●●○○○ -1.55 -1.54806291449783
Escherichia coli M12  CO715_04540  ATI05071.1  600 aa ABC transporter ATP-binding protein 1.7e-5 ●●○○○ -1.55 -1.54785426848359
Escherichia coli M12  CO715_22585  ATI08269.1  428 aa threonine synthase 0.036 ●●○○○ -1.55 -1.54785426848359
Porphyromonas gingivalis ATCC 33277  PGN_0758  WP_004585280.1  B2RIT2  129 aa PEGA domain-containing protein 8.6e-15 ●●○○○ -1.55 -1.5477995284434
Escherichia coli M12  CO715_14935  ATI06893.1  316 aa carbamate kinase 1.7e-24 ●●○○○ -1.55 -1.54722833044084
Retrieved entries 2,601–2,700 out of 36,363 total in 845.1 ms (Link to these results)