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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_08575  ATI05764.1  252 aa DNA-binding transcriptional repressor DeoR 2.5e-10 ●●○○○ -1.55 -1.54701968442659
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1487  CBW17582.1  A0A0H3NBN4  400 aa hypothetical aminotransferase 0.018 ●●○○○ -1.55 -1.54675995681619
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4118  WP_000752579.1  E8XIP6  117 aa membrane protein 0.00052 ●●○○○ -1.55 -1.54608295582709
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2619  WP_000252220.1  E8XGK6  sinH  730 aa intimin-like inverse autotransporter SinH 0.00021 ●●○○○ -1.55 -1.54565428281564
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2415  WP_001056582.1  E8XEG1  nuoL  613 aa NADH-quinone oxidoreductase subunit L 0.002 ●●○○○ -1.55 -1.54512232953083
Escherichia coli M12  CO715_21795  ATI08130.1  334 aa ADP-ribosylglycohydrolase family protein 4.0e-13 ●●○○○ -1.54 -1.5445159322556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4533  AIK83071.1  364 aa fimbrial family protein 0.006 ●●○○○ -1.54 -1.54388592651713
Mycobacterium avium subsp. paratuberculosis K10  MAP_3509  AAS06059.1  Q73U59  615 aa hypothetical protein 0.04 ●●○○○ -1.54 -1.54336463976561
Escherichia coli M12  CO715_00205  ATI04294.1  318 aa sigma-E factor regulatory protein RseB 2.0e-6 ●●○○○ -1.54 -1.54222082609887
Acinetobacter baumannii ATCC 17978  A1S_2773  ABO13185.2  503 aa putative long-chain fatty acid transport protein 5.5e-20 ●●○○○ -1.54 -1.54160999890069
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3518  WP_000723776.1  E8XD61  209 aa GntR family transcriptional regulator 0.0022 ●●○○○ -1.54 -1.53955404493067
Escherichia coli M12  CO715_02865  ATI04771.1  467 aa aldehyde dehydrogenase EutE 5.2e-7 ●●○○○ -1.54 -1.53950842791363
Escherichia coli M12  CO715_03480  ATI04880.1  270 aa tRNA pseudouridine(38-40) synthase TruA 0.0068 ●●○○○ -1.54 -1.53950842791363
Escherichia coli M12  CO715_20830  ATI07953.1  307 aa virulence factor MviM 5.0e-11 ●●○○○ -1.54 -1.53888248987088
Escherichia coli M12  CO715_09495  ATI05925.1  266 aa glucosamine-6-phosphate deaminase 2.7e-14 ●●○○○ -1.54 -1.53804790581389
Mycobacterium avium subsp. paratuberculosis K10  MAP_1560  AAS03877.1  Q73ZP1  140 aa hypothetical protein 0.04 ●●○○○ -1.54 -1.53772585339279
Mycobacterium avium subsp. paratuberculosis K10  MAP_0387  AAS02704.1  Q744F4  186 aa hypothetical protein 0.04 ●●○○○ -1.54 -1.53771061341934
Escherichia coli M12  CO715_18275  ATI07492.1  384 aa S-adenosylmethionine synthase 0.0017 ●●○○○ -1.54 -1.53742196777114
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1323  NP_230967.1  Q9KSD5  160 aa hypothetical protein 8.0e-12 ●●○○○ -1.54 -1.5372077636495
Escherichia coli M12  CO715_18905  ATI07603.1  353 aa hypothetical protein 1.2e-20 ●●○○○ -1.54 -1.5355441536429
Escherichia coli M12  CO715_03120  ATI04814.1  108 aa hypothetical protein 2.8e-8 ●●○○○ -1.54 -1.5355441536429
Mycobacterium avium subsp. paratuberculosis K10  MAP_1028c  AAS03345.1  Q741Q9  141 aa hypothetical protein 0.04 ●●○○○ -1.54 -1.53543569128886
Acinetobacter baumannii ATCC 17978  A1S_0858  ABO11290.1  132 aa putative glutamine-dependent NAD(+) synthetase (NAD(+) synthase 0.0037 ●●○○○ -1.54 -1.53502587536804
Escherichia coli M12  CO715_02355  ATI04676.1  337 aa UDP-glucose--(galactosyl) LPS alpha1,2-glucosyltransferase 3.4e-10 ●●○○○ -1.53 -1.53470956958591
Escherichia coli M12  CO715_13545  ATI06639.1  69 aa hypothetical protein 7.6e-7 ●●○○○ -1.53 -1.53429227755741
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3342  CBW19438.1  A0A0H3NGK0  cafA  489 aa ribonuclease G 0.0056 ●●○○○ -1.53 -1.53425373387814
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3234  WP_001278579.1  E8XAD6  speA  658 aa biosynthetic arginine decarboxylase 0.0018 ●●○○○ -1.53 -1.53395387440655
Mycobacterium avium subsp. paratuberculosis K10  MAP_3118  AAS05666.1  Q73V96  cstA  747 aa CstA 0.04 ●●○○○ -1.53 -1.53350600512541
Porphyromonas gingivalis ATCC 33277  PGN_0593  WP_012457628.1  B2RIB7  traO  194 aa conjugal transfer protein TraO 8.9e-16 ●●○○○ -1.53 -1.53350221536442
Escherichia coli M12  CO715_08345  ATI05721.1  371 aa MacA family efflux pump subunit 2.1e-66 ●●○○○ -1.53 -1.53324904748616
Escherichia coli M12  CO715_05535  ATI05238.1  219 aa DUF533 domain-containing protein 0.001 ●●○○○ -1.53 -1.53304040147192
Mycobacterium avium subsp. paratuberculosis K10  MAP_0400  AAS02717.1  Q744E1  nth  265 aa Nth 0.04 ●●○○○ -1.53 -1.53270219442543
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2892  AIK81481.1  420 aa hflK protein <1e-323 ●●○○○ -1.53 -1.53265170713172
Escherichia coli M12  CO715_19780  ATI07759.1  201 aa recombination protein RecR 6.6e-7 ●●○○○ -1.53 -1.53241446342917
Escherichia coli M12  CO715_10245  ATI06045.1  63 aa DUF1482 domain-containing protein 7.2e-29 ●●○○○ -1.53 -1.53220581741492
Escherichia coli M12  CO715_07440  ATI05562.1  586 aa Lon protease 1.0e-23 ●●○○○ -1.53 -1.53220581741492
Escherichia coli M12  CO715_04905  ATI05130.1  548 aa malate dehydrogenase (quinone) 6.9e-27 ●●○○○ -1.53 -1.53178852538642
Mycobacterium avium subsp. paratuberculosis K10  MAP_4289  AAS06839.1  Q73RY9  436 aa hypothetical protein 0.04 ●●○○○ -1.53 -1.53155531964919
Escherichia coli M12  CO715_09935  ATI06001.1  334 aa iron-enterobactin transporter 9.7e-49 ●●○○○ -1.53 -1.53074529531518
Acinetobacter baumannii ATCC 17978  A1S_1036  ABO11468.2  94 aa hypothetical protein 5.8e-6 ●●○○○ -1.53 -1.52990548487296
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1461  WP_001289628.1  E8XI35  ydgQ  230 aa electron transport complex subunit E 0.0017 ●●○○○ -1.53 -1.52960097476808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3207  AIK81775.1  52 aa ACT domain protein <1e-323 ●●○○○ -1.53 -1.52932220544903
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2890  AIK81479.1  96 aa hypothetical protein 4.2e-9 ●●○○○ -1.53 -1.52906550195443
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1061  WP_000877172.1  E8XE26  ycbg  150 aa macrodomain Ter protein MatP 0.0077 ●●○○○ -1.53 -1.52877642658579
Escherichia coli M12  CO715_14010  ATI06722.1  713 aa lysine decarboxylase LdcC 1.1e-7 ●●○○○ -1.53 -1.52865883517269
Escherichia coli M12  CO715_05360  ATI05206.1  382 aa flagellar type III secretion system protein FlhB 3.2e-8 ●●○○○ -1.53 -1.52845018915844
Mycobacterium avium subsp. paratuberculosis K10  MAP_1743c  AAS04060.1  Q73Z60  333 aa hypothetical protein 0.041 ●●○○○ -1.53 -1.52833015727723
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2197  WP_000091397.1  E8XCV0  wcaD  404 aa putative colanic acid polymerase WcaD 4.8e-10 ●●○○○ -1.53 -1.52808795236295
Mycobacterium avium subsp. paratuberculosis K10  MAP_3563  AAS06113.1  Q73U05  313 aa hypothetical protein 0.041 ●●○○○ -1.53 -1.52789062576704
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1480  WP_000824309.1  E8XI52  ompN  377 aa porin OmpC 4.3e-10 ●●○○○ -1.53 -1.52594461275213
Escherichia coli M12  CO715_24795  ATI08641.1  349 aa two-component system sensor histidine kinase NtrB 9.3e-17 ●●○○○ -1.52 -1.52427726887346
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0558  NP_230209.1  Q9KUG3  426 aa hemolysin 6.4e-6 ●●○○○ -1.52 -1.52399703362403
Mycobacterium avium subsp. paratuberculosis K10  MAP_0755  AAS03072.1  Q742T0  aldA  523 aa AldA_2 0.041 ●●○○○ -1.52 -1.523939686158
Escherichia coli M12  CO715_22020  ATI08172.1  407 aa colanic acid biosynthesis glycosyltransferase WcaI 7.0e-26 ●●○○○ -1.52 -1.52302539278797
Escherichia coli M12  CO715_20485  ATI08876.1  406 aa trimethylamine-N-oxide reductase TorA 8.5e-8 ●●○○○ -1.52 -1.52302539278797
Escherichia coli M12  CO715_12510  ATI06454.1  101 aa hypothetical protein 3.7e-9 ●●○○○ -1.52 -1.52281674677372
Escherichia coli M12  CO715_07520  ATI05576.1  255 aa aliphatic sulfonates ABC transporter ATP-binding protein 0.038 ●●○○○ -1.52 -1.52135622467398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3067  AIK81652.1  267 aa short chain dehydrogenase family protein 2.1e-10 ●●○○○ -1.52 -1.52101267400929
Escherichia coli M12  CO715_11560  ATI06287.1  323 aa PTS mannose transporter subunit EIIAB 1.1e-6 ●●○○○ -1.52 -1.52093893264548
Mycobacterium avium subsp. paratuberculosis K10  MAP_4082  AAS06632.1  Q73SJ1  265 aa hypothetical protein 0.041 ●●○○○ -1.52 -1.52075997215489
Escherichia coli M12  CO715_06640  ATI05420.1  284 aa ModD protein 1.4e-26 ●●○○○ -1.52 -1.51947841054574
Escherichia coli M12  CO715_10570  ATI06102.1  211 aa endonuclease III 6.6e-8 ●●○○○ -1.52 -1.51947841054574
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2845  AIK81434.1  66 aa hypothetical protein 0.00073 ●●○○○ -1.52 -1.51856229558897
Escherichia coli M12  CO715_15850  ATI07052.1  206 aa homoserine/homoserine lactone efflux protein 3.9e-10 ●●○○○ -1.52 -1.5184351804745
Escherichia coli M12  CO715_12765  ATI06502.1  211 aa hypothetical protein 3.0e-9 ●●○○○ -1.52 -1.5184351804745
Escherichia coli M12  CO715_10270  ATI06050.1  339 aa Zn-dependent oxidoreductase 2.2e-13 ●●○○○ -1.52 -1.518017888446
Escherichia coli M12  CO715_08455  ATI05740.1  243 aa arginine/ornithine ABC transporter substrate-binding protein 0.015 ●●○○○ -1.52 -1.51739195040325
Escherichia coli M12  CO715_15790  ATI07042.1  238 aa flavin mononucleotide phosphatase YigB 4.7e-11 ●●○○○ -1.52 -1.51697465837475
Escherichia coli M12  CO715_03550  ATI04894.1  297 aa epimerase 9.3e-9 ●●○○○ -1.52 -1.51697465837475
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1697  NP_231333.1  Q9KRE5  276 aa hypothetical protein 1.2e-6 ●●○○○ -1.52 -1.51633776193412
Porphyromonas gingivalis ATCC 33277  PGN_1610  WP_010955985.1  B2RL84  86 aa hypothetical protein 0.019 ●●○○○ -1.52 -1.51606378784196
Acinetobacter baumannii ATCC 17978  A1S_0529  ABO10982.1  85 aa glutaredoxin 1.4e-16 ●●○○○ -1.52 -1.51576185665675
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4307  WP_001230051.1  E8XL79  argH  458 aa argininosuccinate lyase 0.0023 ●●○○○ -1.52 -1.51546082163857
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1783  WP_000476244.1  E8X8D2  narX  598 aa nitrate/nitrite two-component system sensor histidine kinase NarX 0.0016 ●●○○○ -1.51 -1.51471362538418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3873  AIK82423.1  260 aa mlaE <1e-323 ●●○○○ -1.51 -1.51467339789729
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3274  CBW19370.1  A0A0H3NI79  yhbE  336 aa hypothetical membrane protein 0.011 ●●○○○ -1.51 -1.51384070176776
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1640  NP_231277.1  Q9KRK0  rplY  92 aa 50S ribosomal protein L25 4.5e-9 ●●○○○ -1.51 -1.51347824743954
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2718  WP_001102153.1  E8XHJ1  181 aa terminase small subunit 3.4e-7 ●●○○○ -1.51 -1.51297753912977
Mycobacterium avium subsp. paratuberculosis K10  MAP_3169c  AAS05717.1  Q73V47  261 aa hypothetical protein 0.042 ●●○○○ -1.51 -1.51229360910979
Acinetobacter baumannii ATCC 17978  A1S_0749  ABO11189.2  530 aa BfmS 3.0e-10 ●●○○○ -1.51 -1.51222157173239
Mycobacterium avium subsp. paratuberculosis K10  MAP_1191  AAS03508.1  Q741A1  159 aa hypothetical protein 0.042 ●●○○○ -1.51 -1.51211643522303
Mycobacterium avium subsp. paratuberculosis K10  MAP_0104  AAS02421.1  Q742I6  411 aa hypothetical protein 0.042 ●●○○○ -1.51 -1.51139101883632
Escherichia coli M12  CO715_04695  ATI05095.1  89 aa flagellar biosynthetic protein FliQ 2.0e-8 ●●○○○ -1.51 -1.51113256997579
Escherichia coli M12  CO715_04860  ATI05121.1  216 aa DNA-binding response regulator 1.9e-5 ●●○○○ -1.51 -1.51113256997579
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3772  WP_000185023.1  E8XFB7  529 aa membrane protein 0.0022 ●●○○○ -1.51 -1.51110874563324
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1339  CBW17435.1  A0A0H3NB75  sseG  229 aa Type III secretion system effector protein-modulates the positioning of the SCV 0.011 ●●○○○ -1.51 -1.51083086863631
Mycobacterium avium subsp. paratuberculosis K10  MAP_4118c  AAS06668.1  Q73SF6  lipG  302 aa LipG 0.042 ●●○○○ -1.51 -1.50887655174149
Escherichia coli CFT073  c1603  AAN80071.1  A0A0H2V7Y7  ycgX  134 aa Hypothetical protein ycgX 0.018 ●●○○○ -1.51 -1.50843214233074
Mycobacterium avium subsp. paratuberculosis K10  MAP_1625  AAS03942.1  Q73ZH8  cinA  434 aa CinA 0.042 ●●○○○ -1.51 -1.50809593560265
Escherichia coli M12  CO715_10290  ATI06054.1  113 aa hypothetical protein 0.021 ●●○○○ -1.51 -1.5077942337478
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1092  NP_230737.1  Q9KT13  306 aa oligopeptide transporter permease 6.2e-7 ●●○○○ -1.51 -1.50776274354776
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1270  WP_000617985.1  E8XFJ5  181 aa chorismate mutase 2.2e-10 ●●○○○ -1.51 -1.50774911225997
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3971  CBW20061.1  A0A0H3NUR8  yihW  267 aa hypothetical DeoR-family transcriptional regulator 0.005 ●●○○○ -1.51 -1.50762239211538
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0925  WP_071527454.1  E8XCP6  ybjE  62 aa hypothetical protein 6.8e-15 ●●○○○ -1.51 -1.50694321474662
Mycobacterium avium subsp. paratuberculosis K10  MAP_2150  AAS04467.1  Q741E1  411 aa hypothetical protein 0.042 ●●○○○ -1.51 -1.50653596457719
Mycobacterium avium subsp. paratuberculosis K10  MAP_2274  AAS04591.1  Q741E1  411 aa hypothetical protein 0.042 ●●○○○ -1.51 -1.50627408340316
Escherichia coli M12  CO715_05165  ATI05173.1  328 aa D-cysteine desulfhydrase 1.7e-14 ●●○○○ -1.51 -1.50591641961956
Escherichia coli M12  CO715_04420  ATI05051.1  359 aa nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 6.2e-10 ●●○○○ -1.51 -1.50570777360532
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2001  WP_001276834.1  E8XAB2  fliF  560 aa flagellar basal body M-ring protein FliF 0.00054 ●●○○○ -1.51 -1.50528944143365
Escherichia coli M12  CO715_14755  ATI06862.1  308 aa branched-chain amino acid ABC transporter permease 1.1e-7 ●●○○○ -1.5 -1.50466454353407
Retrieved entries 2,701–2,800 out of 36,363 total in 757.3 ms (Link to these results)