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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3268  WP_001094307.1  E8XAG8  175 aa MaoC family dehydratase 4.1e-5 ●●○○○ -1.35 -1.35327148189036
Escherichia coli M12  CO715_19040  ATI07626.1  330 aa TDT family transporter 0.003 ●●○○○ -1.35 -1.3527702451609
Escherichia coli M12  CO715_21665  ATI08105.1  156 aa DUF1456 domain-containing protein 2.3e-9 ●●○○○ -1.35 -1.35256159914665
Escherichia coli M12  CO715_06905  ATI05467.1  275 aa manganese/iron transporter ATP-binding protein 1.3e-5 ●●○○○ -1.35 -1.35130972306116
Escherichia coli M12  CO715_02365  ATI04678.1  335 aa lipopolysaccharide 3-alpha-galactosyltransferase 0.019 ●●○○○ -1.35 -1.35130972306116
Escherichia coli M12  CO715_19705  ATI07745.1  310 aa glutaminase 7.8e-7 ●●○○○ -1.35 -1.35005784697566
Acinetobacter baumannii ATCC 17978  A1S_2899  ABO13305.2  344 aa putative glycosyltransferase 2.9e-13 ●●○○○ -1.35 -1.34988336233092
Escherichia coli M12  CO715_21325  ATI08042.1  231 aa 16S rRNA pseudouridine(516) synthase 1.8e-9 ●●○○○ -1.35 -1.34984920096142
Escherichia coli M12  CO715_14480  ATI06809.1  355 aa hypothetical protein 0.00046 ●●○○○ -1.35 -1.34964055494717
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4113  AIK82659.1  262 aa bacterial transcriptional regulator family protein <1e-323 ●●○○○ -1.35 -1.34960522618843
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4219  WP_000828052.1  E8XKA4  yiiG  366 aa DUF3829 domain-containing protein 1.1e-8 ●●○○○ -1.35 -1.34960014855028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1694  AIK80314.1  204 aa flavin reductase like domain protein 2.5e-7 ●●○○○ -1.35 -1.34932999825355
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3742  WP_000964735.1  E8XF87  yhhN  208 aa lysoplasmalogenase 0.00094 ●●○○○ -1.35 -1.34909086283379
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3562  CBW19656.1  A0A0H3NMS0  gor  450 aa glutathione reductase 0.016 ●●○○○ -1.35 -1.34866651716672
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2030  NP_231664.1  Q9KQG8  rne  1052 aa ribonuclease E 8.0e-8 ●●○○○ -1.35 -1.34760141879248
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2922  WP_000382035.1  E8XK28  504 aa tripartite tricarboxylate transporter permease 0.012 ●●○○○ -1.35 -1.34753162661152
Escherichia coli M12  CO715_11970  ATI06361.1  162 aa hydrogenase-2 operon protein HybE 3.5e-8 ●●○○○ -1.35 -1.34734544879043
Escherichia coli M12  CO715_06775  ATI05445.1  270 aa septum site-determining protein MinD 6.5e-21 ●●○○○ -1.35 -1.34713680277618
Escherichia coli M12  CO715_09945  ATI06003.1  271 aa ferric enterobactin transport ATP-binding protein FepC 1.3e-8 ●●○○○ -1.35 -1.34671951074768
Escherichia coli M12  CO715_05485  ATI05228.1  440 aa murein DD-endopeptidase MepM 2.9e-15 ●●○○○ -1.35 -1.34651086473343
Acinetobacter baumannii ATCC 17978  A1S_3321  ABO13710.2  488 aa IMP dehydrogenase 0.00037 ●●○○○ -1.35 -1.34605761444656
Escherichia coli M12  CO715_21915  ATI08152.1  153 aa hypothetical protein 5.8e-21 ●●○○○ -1.35 -1.34588492669069
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0546  NP_232936.1  Q9KM43  318 aa hypothetical protein 0.00014 ●●○○○ -1.35 -1.34535985877332
Acinetobacter baumannii ATCC 17978  A1S_0880  ABO11312.2  270 aa minC activating cell division inhibitor a membrane ATPase 1.0e-11 ●●○○○ -1.35 -1.34530742845772
Escherichia coli M12  CO715_22140  ATI08192.1  491 aa ketol-acid reductoisomerase 3.6e-33 ●●○○○ -1.35 -1.34525898864794
Escherichia coli M12  CO715_11965  ATI06360.1  164 aa hydrogenase 2 maturation protease 5.9e-5 ●●○○○ -1.35 -1.34525898864794
Escherichia coli M12  CO715_11650  ATI06301.1  273 aa undecaprenyl-diphosphatase 0.00078 ●●○○○ -1.35 -1.34525898864794
Acinetobacter baumannii ATCC 17978  A1S_2901  ABO13307.2  250 aa putative polysaccharide deacetylase 3.0e-7 ●●○○○ -1.35 -1.34516283912332
Escherichia coli M12  CO715_00405  ATI04328.1  61 aa addiction module toxin, HicA family 1.8e-10 ●●○○○ -1.34 -1.34463305060519
Escherichia coli M12  CO715_06700  ATI05431.1  510 aa SpoVR family protein 4.8e-8 ●●○○○ -1.34 -1.3442157585767
Escherichia coli M12  CO715_00820  ATI04404.1  137 aa heat-shock protein IbpA 8.6e-6 ●●○○○ -1.34 -1.3442157585767
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4308  AIK82853.1  370 aa iron-containing alcohol dehydrogenase family protein 0.0015 ●●○○○ -1.34 -1.34415685327023
Escherichia coli M12  CO715_11870  ATI06342.1  275 aa 2,5-diketo-D-gluconic acid reductase A 2.5e-7 ●●○○○ -1.34 -1.34254659046271
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1802  AIK80414.1  427 aa citrate (Si)-synthase <1e-323 ●●○○○ -1.34 -1.3423843254748
Escherichia coli M12  CO715_19280  ATI07669.1  171 aa methylated-DNA--[protein]-cysteine S-methyltransferase 0.0024 ●●○○○ -1.34 -1.34212929843421
Escherichia coli M12  CO715_19020  ATI07622.1  178 aa XRE family transcriptional regulator 2.0e-6 ●●○○○ -1.34 -1.34171200640571
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3720  WP_000073548.1  E8XF65  ugpQ  246 aa glycerophosphodiester phosphodiesterase 7.1e-8 ●●○○○ -1.34 -1.34143858227408
Escherichia coli M12  CO715_14785  ATI06868.1  281 aa sn-glycerol 3-phosphate ABC transporter permease 1.9e-57 ●●○○○ -1.34 -1.34004283829172
Escherichia coli M12  CO715_13530  ATI06637.1  79 aa hypothetical protein 5.4e-5 ●●○○○ -1.34 -1.33941690024897
Escherichia coli M12  CO715_10690  ATI06123.1  193 aa superoxide dismutase [Fe] 0.00015 ●●○○○ -1.34 -1.33941690024897
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1750  AIK80370.1  244 aa putative transcriptional regulator predicted DNA-binding transcriptional regulator 5.3e-13 ●●○○○ -1.34 -1.33929241306998
Escherichia coli M12  CO715_02695  ATI04740.1  526 aa hydrogenase 1.8e-39 ●●○○○ -1.34 -1.33858231619198
Escherichia coli M12  CO715_10990  ATI06178.1  183 aa glutathione peroxidase 7.7e-22 ●●○○○ -1.34 -1.33858231619198
Escherichia coli M12  CO715_10810  ATI06144.1  334 aa murein L,D-transpeptidase 2.5e-22 ●●○○○ -1.34 -1.33816502416348
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3326  AIK81883.1  146 aa flavodoxin family protein <1e-323 ●●○○○ -1.34 -1.33801262153476
Escherichia coli M12  CO715_03135  ATI04817.1  108 aa fructose-like phosphotransferase enzyme IIB component 1 3.9e-5 ●●○○○ -1.34 -1.33774773213498
Escherichia coli M12  CO715_19255  ATI07665.1  302 aa LysR family transcriptional regulator 3.8e-16 ●●○○○ -1.34 -1.33753908612073
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0554  WP_000815603.1  E8X8C0  purK  355 aa 5-(carboxyamino)imidazole ribonucleotide synthase 0.0079 ●●○○○ -1.34 -1.33704118307636
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2375  WP_000533921.1  E8XEC1  yfaE  84 aa ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE 1.0e-8 ●●○○○ -1.34 -1.33694335976209
Escherichia coli M12  CO715_01330  ATI04493.1  141 aa transcriptional regulator 0.0016 ●●○○○ -1.34 -1.33691314807799
Acinetobacter baumannii ATCC 17978  A1S_0438  ABO10893.2  149 aa hypothetical protein 8.6e-10 ●●○○○ -1.34 -1.33657035945992
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4091  WP_001089447.1  E8XIM4  gppA  493 aa guanosine-5'-triphosphate,3'-diphosphate diphosphatase 0.0065 ●●○○○ -1.34 -1.33542614960305
Escherichia coli M12  CO715_20905  ATI07968.1  317 aa flagellar hook-filament junction protein FlgL 5.0e-27 ●●○○○ -1.34 -1.335243979964
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2878  AIK81467.1  354 aa phosphodiesterase / predicted L-ascorbate 6-phosphate lactonase <1e-323 ●●○○○ -1.33 -1.33297293799521
Escherichia coli M12  CO715_06175  ATI05341.1  229 aa type 1 glutamine amidotransferase domain-containing protein 0.0039 ●●○○○ -1.33 -1.33294887380726
Escherichia coli M12  CO715_21150  ATI08014.1  216 aa hypothetical protein 8.7e-11 ●●○○○ -1.33 -1.33274022779301
Escherichia coli M12  CO715_23850  ATI08475.1  197 aa antibiotic transporter 4.2e-6 ●●○○○ -1.33 -1.33232293576451
Escherichia coli M12  CO715_06400  ATI05382.1  280 aa formyltetrahydrofolate deformylase 2.9e-171 ●●○○○ -1.33 -1.33190564373601
Escherichia coli M12  CO715_11615  ATI06295.1  47 aa PhoP regulon feedback inhibition membrane protein MgrB 0.04 ●●○○○ -1.33 -1.33169699772176
Acinetobacter baumannii ATCC 17978  A1S_0470  ABO10925.2  197 aa methionine biosynthesis protein 2.5e-15 ●●○○○ -1.33 -1.33151730934842
Escherichia coli M12  CO715_17240  ATI07308.1  445 aa MFS transporter 6.6e-49 ●●○○○ -1.33 -1.33148835170752
Escherichia coli M12  CO715_05175  ATI05175.1  250 aa L-cystine ABC transporter ATP-binding protein YecC 3.9e-13 ●●○○○ -1.33 -1.33148835170752
Escherichia coli M12  CO715_22975  ATI08336.1  227 aa hypothetical protein 3.2e-7 ●●○○○ -1.33 -1.33148835170752
Escherichia coli M12  CO715_00585  ATI04363.1  324 aa bifunctional glyoxylate/hydroxypyruvate reductase B 1.4e-44 ●●○○○ -1.33 -1.33086241366477
Escherichia coli M12  CO715_20335  ATI07865.1  275 aa taurine transporter subunit 1.8e-11 ●●○○○ -1.33 -1.33065376765052
Escherichia coli M12  CO715_06630  ATI05418.1  252 aa ABC transporter ATP-binding protein 9.2e-31 ●●○○○ -1.33 -1.33044512163627
Escherichia coli M12  CO715_10410  ATI06073.1  314 aa DUF1471 domain-containing protein 2.6e-32 ●●○○○ -1.33 -1.32981918359353
Escherichia coli M12  CO715_15770  ATI07038.1  67 aa hypothetical protein 0.004 ●●○○○ -1.33 -1.32940189156503
Escherichia coli M12  CO715_16715  ATI07214.1  109 aa hypothetical protein 0.0001 ●●○○○ -1.33 -1.32898459953653
Escherichia coli M12  CO715_02450  ATI04694.1  274 aa DNA damage-inducible protein D 2.9e-69 ●●○○○ -1.33 -1.32877595352228
Escherichia coli M12  CO715_15080  ATI06921.1  329 aa aldo/keto reductase 2.3e-44 ●●○○○ -1.33 -1.32877595352228
Escherichia coli M12  CO715_10090  ATI06025.1  57 aa protein GnsB 1.4e-7 ●●○○○ -1.33 -1.32815001547953
Escherichia coli M12  CO715_04625  ATI05083.1  231 aa phosphohydrolase 1.1e-13 ●●○○○ -1.33 -1.32794136946529
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2429  NP_232059.1  Q9KPE1  yacG  65 aa zinc-binding protein 3.2e-8 ●●○○○ -1.33 -1.32791983165658
Escherichia coli M12  CO715_20035  ATI07808.1  303 aa 2-dehydropantoate 2-reductase 1.5e-6 ●●○○○ -1.33 -1.32752407743679
Escherichia coli M12  CO715_07830  ATI05628.1  129 aa RusA family crossover junction endodeoxyribonuclease 1.5e-7 ●●○○○ -1.33 -1.3258549093228
Acinetobacter baumannii ATCC 17978  A1S_0045  ABO10540.2  189 aa regulating N-acetyl-anhydromuramyl-L-alanine amidase 0.00013 ●●○○○ -1.33 -1.32543234142511
Escherichia coli M12  CO715_10485  ATI06087.1  196 aa TetR family transcriptional regulator 1.5e-18 ●●○○○ -1.33 -1.32522897128005
Escherichia coli M12  CO715_10205  ATI06039.1  356 aa phage replisome organizer 4.4e-94 ●●○○○ -1.32 -1.32481167925155
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4035  AIK82582.1  131 aa hypothetical protein 2.4e-12 ●●○○○ -1.32 -1.32317143927338
Escherichia coli M12  CO715_00210  ATI04295.1  159 aa SoxR reducing system protein RseC 3.7e-12 ●●○○○ -1.32 -1.32105605099507
Escherichia coli M12  CO715_03530  ATI04890.1  228 aa histidine ABC transporter permease 7.6e-7 ●●○○○ -1.32 -1.32043011295233
Escherichia coli M12  CO715_00135  ATI04282.1  392 aa outer membrane protein assembly factor BamB 1.3e-6 ●●○○○ -1.32 -1.32043011295233
Escherichia coli M12  CO715_03020  ATI04800.1  323 aa cysteine synthase A 0.00048 ●●○○○ -1.32 -1.32043011295233
Escherichia coli M12  CO715_10120  ATI06029.1  103 aa hypothetical protein 9.7e-6 ●●○○○ -1.32 -1.32022146693808
Escherichia coli M12  CO715_08145  ATI05685.1  410 aa winged helix-turn-helix domain-containing protein 3.9e-5 ●●○○○ -1.32 -1.32022146693808
Escherichia coli M12  CO715_24380  ATI08572.1  176 aa hypothetical protein 1.7e-11 ●●○○○ -1.32 -1.31959552889533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3834  AIK82384.1  209 aa bacterial regulatory, gntR family protein <1e-323 ●●○○○ -1.32 -1.31951874340471
Escherichia coli M12  CO715_11135  ATI06206.1  112 aa osmotically-inducible lipoprotein E 7.9e-13 ●●○○○ -1.32 -1.31876094483834
Escherichia coli M12  CO715_22170  ATI08198.1  109 aa thiol reductase thioredoxin 2.4e-7 ●●○○○ -1.32 -1.31813500679559
Escherichia coli M12  CO715_12155  ATI06395.1  123 aa type II secretion system protein GspI 3.5e-28 ●●○○○ -1.32 -1.31792636078134
Escherichia coli M12  CO715_14135  ATI06745.1  385 aa carbohydrate diacid regulon transcriptional regulator CdaR 0.00018 ●●○○○ -1.32 -1.31792636078134
Escherichia coli M12  CO715_09850  ATI05984.1  521 aa alkyl hydroperoxide reductase subunit F 7.7e-43 ●●○○○ -1.32 -1.31771771476709
Escherichia coli M12  CO715_08505  ATI05750.1  53 aa putrescine/spermidine ABC transporter substrate-binding protein 2.1e-7 ●●○○○ -1.32 -1.31709177672434
Escherichia coli M12  CO715_02950  ATI04786.1  474 aa PTS N-acetylmuramic acid transporter subunits IIBC 1.4e-7 ●●○○○ -1.32 -1.3168831307101
Escherichia coli M12  CO715_00185  ATI04290.1  245 aa tRNA (adenosine(37)-N6)-methyltransferase TrmM 2.3e-6 ●●○○○ -1.32 -1.31625719266735
Escherichia coli M12  CO715_11410  ATI06259.1  393 aa cyanate MFS transporter 6.8e-39 ●●○○○ -1.32 -1.31583990063885
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3681  CBW19775.1  A0A0H3NHF5  rfaZ  269 aa lipopolysaccharide core biosynthesis protein RfaZ 0.0052 ●●○○○ -1.32 -1.31571244173426
Acinetobacter baumannii ATCC 17978  A1S_2153  ABO12580.2  273 aa methyl transferase 4.8e-14 ●●○○○ -1.32 -1.31504055751369
Escherichia coli M12  CO715_16950  ATI08842.1  474 aa 6-phospho-beta-glucosidase 1.3e-44 ●●○○○ -1.31 -1.31479667056761
Retrieved entries 3,201–3,300 out of 36,363 total in 755.4 ms (Link to these results)