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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_12445  ATI06444.1  227 aa hypothetical protein 2.8e-77 ●○○○○ -0.79 -0.788174130603481
Escherichia coli M12  CO715_10925  ATI06165.1  312 aa electron transfer flavoprotein subunit alpha 3.4e-15 ●○○○○ -0.79 -0.786922254517988
Porphyromonas gingivalis ATCC 33277  PGN_1617  WP_012458409.1  B2RL91  489 aa metallophosphoesterase family protein 4.2e-9 ●○○○○ -0.79 -0.78680264561056
Escherichia coli M12  CO715_04740  ATI05104.1  228 aa flagellar assembly protein FliH 3.3e-18 ●○○○○ -0.79 -0.786713608503739
Acinetobacter baumannii ATCC 17978  A1S_2604  ABO13021.2  397 aa putative permease (PerM family) 1.9e-5 ●○○○○ -0.79 -0.786315325265307
Acinetobacter baumannii ATCC 17978  A1S_1525  ABO11952.2  248 aa hypothetical protein 0.013 ●○○○○ -0.79 -0.785465044826513
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4382  AIK82925.1  450 aa D-galactonate transporter family protein <1e-323 ●○○○○ -0.79 -0.785314810018531
Porphyromonas gingivalis ATCC 33277  PGN_0030  WP_051892375.1  B2RGQ4  861 aa glycoside hydrolase family 2 protein 0.0016 ●○○○○ -0.78 -0.784723016546029
Escherichia coli M12  CO715_10420  ATI06075.1  460 aa arginine:ornithine antiporter 8.8e-21 ●○○○○ -0.78 -0.784627148361251
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3217  WP_014344170.1  E8X9P1  epd  66 aa hypothetical protein 0.011 ●○○○○ -0.78 -0.784426420387178
Porphyromonas gingivalis ATCC 33277  PGN_0592  WP_012457627.1  B2RIB6  traQ  145 aa DUF3872 domain-containing protein <1e-323 ●○○○○ -0.78 -0.782638909146992
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3450  AIK82006.1  240 aa helix-turn-helix domain, rpiR family protein <1e-323 ●○○○○ -0.78 -0.781673046644265
Porphyromonas gingivalis ATCC 33277  PGN_1723  WP_012458485.1  B2RLJ7  395 aa DUF2029 domain-containing protein <1e-323 ●○○○○ -0.78 -0.780550304084268
Escherichia coli M12  CO715_04910  ATI05131.1  162 aa ecotin 0.00024 ●○○○○ -0.78 -0.780454228076274
Acinetobacter baumannii ATCC 17978  A1S_1962  ABO12389.2  A3M645  recA  349 aa DNA strand exchange and recombination protein 0.0064 ●○○○○ -0.78 -0.778318687867481
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2690  AIK81284.1  464 aa diguanylate cyclase domain protein 0.039 ●○○○○ -0.78 -0.776459282054829
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1682  NP_231318.1  Q9KRG0  295 aa peptide ABC transporter permease 4.8e-5 ●○○○○ -0.78 -0.776370032321797
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0921  NP_230568.1  Q9KTI1  469 aa polysaccharide export protein 2.5e-5 ●○○○○ -0.78 -0.776300314615012
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3849  AIK82399.1  212 aa stringent starvation protein A 1.5e-5 ●○○○○ -0.78 -0.776035579069185
Escherichia coli M12  CO715_06865  ATI05460.1  243 aa helix-turn-helix-type transcriptional regulator 1.9e-5 ●○○○○ -0.77 -0.774612139677306
Porphyromonas gingivalis ATCC 33277  PGN_0016  WP_012457172.1  B2RGP0  333 aa tRNA dihydrouridine synthase DusB <1e-323 ●○○○○ -0.77 -0.774574722844405
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3644  WP_000349895.1  E8XEI0  cysG  457 aa uroporphyrinogen-III C-methyltransferase 0.022 ●○○○○ -0.77 -0.774517137803352
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0741  NP_233128.1  Q9KLK2  106 aa hypothetical protein 7.9e-6 ●○○○○ -0.77 -0.774206323985932
Escherichia coli M12  CO715_09650  ATI05948.1  235 aa DUF1266 domain-containing protein 9.0e-23 ●○○○○ -0.77 -0.77377755562031
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4797  WP_001253768.1  E8XDC5  sthE  361 aa type 1 fimbrial protein 0.00026 ●○○○○ -0.77 -0.772656775900662
Porphyromonas gingivalis ATCC 33277  PGN_1682  WP_012458455.1  B2RLF6  458 aa FtsX-like permease family protein <1e-323 ●○○○○ -0.77 -0.772155647783648
Escherichia coli M12  CO715_22870  ATI08318.1  423 aa TRAP transporter large permease 4.9e-9 ●○○○○ -0.77 -0.772108387506319
Acinetobacter baumannii ATCC 17978  A1S_1008  ABO11440.2  534 aa isocitrate lyase 9.4e-7 ●○○○○ -0.77 -0.772077345250225
Escherichia coli M12  CO715_20375  ATI07872.1  369 aa S-(hydroxymethyl)glutathione dehydrogenase 0.00028 ●○○○○ -0.77 -0.771482449463573
Porphyromonas gingivalis ATCC 33277  PGN_1744  WP_021662358.1  B2RLL8  204 aa PorT family protein 9.3e-8 ●○○○○ -0.77 -0.770887319365595
Escherichia coli M12  CO715_16400  ATI07156.1  254 aa hypothetical protein 1.6e-5 ●○○○○ -0.77 -0.770647865406577
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1698  WP_014343844.1  E8XK14  ycjX  467 aa YcjX family protein 0.0037 ●○○○○ -0.77 -0.77054096568259
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3937  AIK82485.1  122 aa hypothetical protein 0.0023 ●○○○○ -0.77 -0.76947128883559
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2946  WP_000777903.1  E8XK52  nrdF  319 aa ribonucleoside-diphosphate reductase 2 subunit beta 0.0017 ●○○○○ -0.77 -0.769242856482192
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2514  AIK81111.1  231 aa L-ribulose-5-phosphate 4-epimerase <1e-323 ●○○○○ -0.77 -0.768356799366022
Porphyromonas gingivalis ATCC 33277  PGN_1038  WP_004584135.1  B2RJL2  180 aa arginine decarboxylase <1e-323 ●○○○○ -0.77 -0.767536492626147
Escherichia coli M12  CO715_02435  ATI04691.1  238 aa ribonuclease PH 0.00085 ●○○○○ -0.77 -0.767518175192844
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3395  AIK81952.1  442 aa uhpC <1e-323 ●○○○○ -0.77 -0.76695104216466
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3406  WP_001057715.1  E8XC66  garL  256 aa 2-dehydro-3-deoxyglucarate aldolase 0.0015 ●○○○○ -0.77 -0.766950493279997
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2116  AIK80721.1  356 aa lacI transcriptional repressor 8.0e-8 ●○○○○ -0.76 -0.764915124667677
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1545  NP_231185.1  Q9ZHV9  exbD2  134 aa TonB system transport protein ExbD2 0.0001 ●○○○○ -0.76 -0.764796069402339
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2916  AIK81503.1  100 aa small Multidrug Resistance family protein 5.2e-7 ●○○○○ -0.76 -0.764720448065452
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3553  WP_000160383.1  E8XD96  acrE  385 aa efflux RND transporter periplasmic adaptor subunit 0.00044 ●○○○○ -0.76 -0.764706328715819
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1366  AIK79989.1  477 aa ptsG 6.7e-16 ●○○○○ -0.76 -0.76450715125431
Porphyromonas gingivalis ATCC 33277  PGN_0314  WP_012457418.1  B2RHI8  261 aa formate/nitrite transporter family protein <1e-323 ●○○○○ -0.76 -0.764360272488666
Porphyromonas gingivalis ATCC 33277  PGN_1269  WP_012458157.1  B2RK93  455 aa lactate utilization protein <1e-323 ●○○○○ -0.76 -0.763392424689596
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2325  AIK80929.1  264 aa ubiquinone oxidoreductase, Na(+)-translocating, C subunit <1e-323 ●○○○○ -0.76 -0.762879351883404
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0914  NP_233299.1  Q9KL35  343 aa hemin ABC transporter permease 0.00089 ●○○○○ -0.76 -0.76245038873989
Escherichia coli M12  CO715_24180  ATI08537.1  374 aa DNA-protecting protein DprA 9.3e-35 ●○○○○ -0.76 -0.762302024836623
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0726  NP_230375.1  Q9KU04  pstB1  273 aa phosphate transporter ATP-binding protein 0.0052 ●○○○○ -0.76 -0.76215574147133
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2251  WP_000569166.1  E8XD04  yehX  315 aa ABC transporter ATP-binding protein 0.00039 ●○○○○ -0.76 -0.761998222919449
Escherichia coli M12  CO715_13890  ATI06702.1  220 aa iron-sulfur cluster repair protein YtfE 6.5e-7 ●○○○○ -0.76 -0.761050148751129
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2342  AIK80945.1  258 aa endonuclease/Exonuclease/phosphatase family protein 3.0e-15 ●○○○○ -0.76 -0.760755068043329
Escherichia coli M12  CO715_15405  ATI06977.1  300 aa cation-efflux pump FieF 3.8e-18 ●○○○○ -0.76 -0.760215564694134
Escherichia coli M12  CO715_21445  ATI08065.1  362 aa kinase 1.6e-11 ●○○○○ -0.76 -0.760215564694134
Escherichia coli M12  CO715_13260  ATI06591.1  197 aa septum formation inhibitor Maf 2.8e-17 ●○○○○ -0.76 -0.760006918679885
Escherichia coli M12  CO715_01335  ATI04494.1  432 aa adenylosuccinate synthetase 8.1e-5 ●○○○○ -0.76 -0.759589626651388
Acinetobacter baumannii ATCC 17978  A1S_1474  ABO11902.2  A3M4Q8  glnD  887 aa uridylyltransferase 0.021 ●○○○○ -0.76 -0.759098233371278
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0049  NP_229708.1  Q9KVU0  smg  158 aa hypothetical protein 0.0002 ●○○○○ -0.76 -0.75888307801826
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2323  AIK80927.1  198 aa ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3.3e-16 ●○○○○ -0.76 -0.758514946941891
Porphyromonas gingivalis ATCC 33277  PGN_1929  WP_012458615.1  B2RM53  145 aa hypothetical protein 2.1e-13 ●○○○○ -0.76 -0.758325214894085
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2184  NP_231815.1  Q9KQ21  pth  196 aa peptidyl-tRNA hydrolase 0.00028 ●○○○○ -0.76 -0.75787688513115
Escherichia coli M12  CO715_03150  ATI04820.1  345 aa aminopeptidase 1.5e-31 ●○○○○ -0.76 -0.757503166508899
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3287  WP_000190182.1  E8XAI7  uxaC  470 aa glucuronate isomerase 0.00072 ●○○○○ -0.76 -0.756694108006115
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0331  WP_001292977.1  E8XJL8  pepD  485 aa cytosol nonspecific dipeptidase 0.0059 ●○○○○ -0.76 -0.75618734044671
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2223  NP_231854.1  Q9KPY9  340 aa 23S rRNA pseudouridine synthase F 3.5e-7 ●○○○○ -0.76 -0.755501866409599
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1044  NP_233426.1  Q9KKQ8  47 aa hypothetical protein 0.00026 ●○○○○ -0.76 -0.755341267674234
Escherichia coli M12  CO715_23575  ATI08428.1  271 aa HTH-type transcriptional repressor AllR 1.1e-19 ●○○○○ -0.75 -0.754790768323664
Escherichia coli M12  CO715_01540  ATI04529.1  112 aa divalent-cation tolerance protein CutA 0.043 ●○○○○ -0.75 -0.754582122309415
Porphyromonas gingivalis ATCC 33277  PGN_2073  WP_004585611.1  B2RMJ6  339 aa NAD(P)-dependent oxidoreductase <1e-323 ●○○○○ -0.75 -0.754570030493438
Escherichia coli M12  CO715_16795  ATI07230.1  390 aa multidrug export protein EmrA 1.9e-12 ●○○○○ -0.75 -0.754164830280917
Acinetobacter baumannii ATCC 17978  A1S_2377  ABO12796.1  175 aa putative ABC transporter 0.037 ●○○○○ -0.75 -0.7540617494858
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1841  WP_000290594.1  E8X8J0  slp  193 aa Slp family lipoprotein 0.00034 ●○○○○ -0.75 -0.753515160323522
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3255  AIK81816.1  300 aa yiiP <1e-323 ●○○○○ -0.75 -0.753430480767829
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3377  AIK81935.1  240 aa putative transcriptional regulator <1e-323 ●○○○○ -0.75 -0.753124851386771
Acinetobacter baumannii ATCC 17978  A1S_2025  ABO12452.1  173 aa hypothetical protein 0.00038 ●○○○○ -0.75 -0.753104561427963
Escherichia coli M12  CO715_12460  ATI06446.1  59 aa hypothetical protein 0.037 ●○○○○ -0.75 -0.752495662166926
Escherichia coli M12  CO715_15350  ATI06968.1  489 aa rhamnulokinase 1.8e-12 ●○○○○ -0.75 -0.752078370138429
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4478  AIK83021.1  326 aa PTS system, glucitol/sorbitol-specific, IIBC component family protein 2.3e-7 ●○○○○ -0.75 -0.752052161097731
Escherichia coli M12  CO715_15865  ATI07055.1  299 aa EamA family transporter 5.1e-5 ●○○○○ -0.75 -0.751661078109931
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2855  AIK81445.1  231 aa 3'(2'),5'-bisphosphate nucleotidase <1e-323 ●○○○○ -0.75 -0.751651418298945
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1665  NP_231301.1  Q9KRH7  566 aa ABC transporter permease 0.00039 ●○○○○ -0.75 -0.750990287557811
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1577  AIK80197.1  57 aa hypothetical protein 0.00069 ●○○○○ -0.75 -0.750770141489634
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0711  NP_233098.1  Q9KLN2  mgsA  151 aa methylglyoxal synthase 0.023 ●○○○○ -0.75 -0.750438305911988
Porphyromonas gingivalis ATCC 33277  PGN_0334  WP_012457435.1  B2RHK8  432 aa DUF1343 domain-containing protein 7.3e-12 ●○○○○ -0.75 -0.750406684365628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4398  AIK82941.1  570 aa sulfite reductase (NADPH) hemoprotein, beta-component 2.6e-15 ●○○○○ -0.75 -0.749786560239249
Escherichia coli M12  CO715_06455  ATI05388.1  598 aa nitrate/nitrite two-component system sensor histidine kinase NarX 6.5e-15 ●○○○○ -0.75 -0.749574617967442
Porphyromonas gingivalis ATCC 33277  PGN_0871  WP_012457840.1  B2RJ45  403 aa hypothetical protein 0.00083 ●○○○○ -0.75 -0.749445788062644
Escherichia coli M12  CO715_20575  ATI07908.1  1320 aa trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase 8.7e-190 ●○○○○ -0.75 -0.748948679924695
Escherichia coli M12  CO715_09085  ATI05858.1  347 aa quinolinate synthase 2.6e-5 ●○○○○ -0.75 -0.748740033910447
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2633  WP_001014757.1  E8XGM0  pbpC  771 aa peptidoglycan glycosyltransferase PbpC 0.00038 ●○○○○ -0.75 -0.74838014674736
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1654  WP_000048924.1  E8XJX2  acpD  201 aa FMN-dependent NADH-azoreductase 0.00038 ●○○○○ -0.75 -0.74801072546848
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2156  NP_231787.1  Q9KQ48  bamC  339 aa lipoprotein 1.6e-5 ●○○○○ -0.75 -0.747521069304016
Porphyromonas gingivalis ATCC 33277  PGN_0391  WP_012457474.1  B2RHR5  472 aa PDZ domain-containing protein <1e-323 ●○○○○ -0.75 -0.746515207868131
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0180  NP_232580.1  Q9KMY6  pepT  410 aa peptidase T 1.3e-6 ●○○○○ -0.75 -0.746382447134059
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4194  AIK82739.1  572 aa urease, alpha subunit <1e-323 ●○○○○ -0.75 -0.746208210433264
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4016  AIK82563.1  945 aa glnD PII-uridylyltransferase family protein <1e-323 ●○○○○ -0.75 -0.745706301582673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2612  AIK81206.1  415 aa PTS system, lactose/cellobiose IIC component family protein <1e-323 ●○○○○ -0.75 -0.745429756493662
Escherichia coli M12  CO715_03875  ATI04954.1  75 aa ferrous iron transporter A 4.8e-52 ●○○○○ -0.75 -0.745401697682465
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0579  NP_230230.1  Q9KUE2  gmhA  196 aa phosphoheptose isomerase 2.0e-6 ●○○○○ -0.75 -0.745358391790503
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