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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_10820  ATI06146.1  406 aa cysteine desulfurase 6.0e-6 ●○○○○ -0.55 -0.547187984146047
Escherichia coli M12  CO715_11505  ATI06276.1  636 aa ATP-dependent DNA helicase 1.8e-6 ●○○○○ -0.55 -0.546353400089051
Escherichia coli M12  CO715_06030  ATI05314.1  127 aa MDR efflux pump AcrAB transcriptional activator MarA 0.021 ●○○○○ -0.55 -0.546353400089051
Escherichia coli M12  CO715_08540  ATI05757.1  561 aa transporter 3.0e-7 ●○○○○ -0.54 -0.543849647918065
Escherichia coli M12  CO715_21280  ATI08036.1  836 aa outer membrane autotransporter barrel domain-containing protein 2.0e-7 ●○○○○ -0.54 -0.543641001903816
Escherichia coli M12  CO715_01840  ATI04583.1  437 aa glutamate/aspartate:proton symporter GltP 4.8e-7 ●○○○○ -0.54 -0.542180479804074
Escherichia coli M12  CO715_12985  ATI06541.1  211 aa phospholipid-binding protein 2.0e-5 ●○○○○ -0.54 -0.539676727633088
Escherichia coli M12  CO715_07480  ATI05569.1  369 aa hypothetical protein 5.1e-12 ●○○○○ -0.54 -0.538842143576092
Escherichia coli M12  CO715_09640  ATI05946.1  184 aa sel1 repeat family protein 2.1e-17 ●○○○○ -0.54 -0.538216205533346
Escherichia coli M12  CO715_21790  ATI08129.1  321 aa sugar kinase 1.8e-23 ●○○○○ -0.54 -0.53738162147635
Escherichia coli M12  CO715_24485  ATI08589.1  256 aa putative lateral flagellar export/assembly protein LafU 0.0044 ●○○○○ -0.53 -0.531539533077382
Escherichia coli M12  CO715_17235  ATI07307.1  259 aa electron transfer flavoprotein 2.0e-5 ●○○○○ -0.53 -0.530287656991889
Escherichia coli M12  CO715_05675  ATI05260.1  121 aa host cell division inhibitor Icd-like protein 4.4e-14 ●○○○○ -0.53 -0.53007901097764
Escherichia coli M12  CO715_09600  ATI05939.1  302 aa amino acid ABC transporter substrate-binding protein 0.0017 ●○○○○ -0.53 -0.529035780906396
Escherichia coli M12  CO715_02910  ATI04779.1  350 aa AraC family transcriptional regulator 2.2e-9 ●○○○○ -0.53 -0.528827134892147
Escherichia coli M12  CO715_18045  ATI07452.1  200 aa 5-formyltetrahydrofolate cyclo-ligase 0.00013 ●○○○○ -0.52 -0.523819630550174
Escherichia coli M12  CO715_17045  ATI07271.1  853 aa DNA mismatch repair protein MutS 5.1e-118 ●○○○○ -0.52 -0.523193692507428
Escherichia coli M12  CO715_03125  ATI04815.1  418 aa ion channel protein 2.8e-19 ●○○○○ -0.52 -0.520689940336441
Escherichia coli M12  CO715_00275  ATI04307.1  282 aa MurR/RpiR family transcriptional regulator 4.5e-5 ●○○○○ -0.52 -0.518812126208202
Escherichia coli M12  CO715_02845  ATI04768.1  267 aa ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT 1.5e-7 ●○○○○ -0.52 -0.51547378998022
Escherichia coli M12  CO715_23275  ATI08387.1  73 aa hypothetical protein 7.0e-30 ●○○○○ -0.51 -0.512761391794985
Escherichia coli M12  CO715_18135  ATI07467.1  291 aa mechanosensitive ion channel protein MscS 7.0e-41 ●○○○○ -0.51 -0.511509515709491
Escherichia coli M12  CO715_19435  ATI07699.1  321 aa antimicrobial peptide ABC transporter permease SapB 0.00061 ●○○○○ -0.51 -0.511092223680994
Escherichia coli M12  CO715_13670  ATI06662.1  334 aa ornithine carbamoyltransferase 0.0016 ●○○○○ -0.51 -0.510257639623998
Escherichia coli M12  CO715_14425  ATI06798.1  250 aa ribosomal RNA small subunit methyltransferase J 0.0097 ●○○○○ -0.51 -0.51004899360975
Escherichia coli M12  CO715_19470  ATI07706.1  375 aa CMD domain-containing protein 1.5e-7 ●○○○○ -0.51 -0.509840347595501
Escherichia coli M12  CO715_21980  ATI08164.1  162 aa colanic acid biosynthesis acetyltransferase WcaB 1.1e-5 ●○○○○ -0.51 -0.509840347595501
Escherichia coli M12  CO715_15385  ATI06974.1  224 aa MOSC domain-containing protein 5.0e-5 ●○○○○ -0.51 -0.509005763538505
Escherichia coli M12  CO715_11915  ATI06351.1  164 aa TIGR00645 family protein 3.0e-16 ●○○○○ -0.51 -0.507962533467261
Escherichia coli M12  CO715_00420  ATI04331.1  466 aa MFS transporter 4.4e-95 ●○○○○ -0.51 -0.507336595424514
Escherichia coli M12  CO715_07135  ATI05510.1  380 aa integrase 1.6e-12 ●○○○○ -0.51 -0.505041489267777
Escherichia coli M12  CO715_09970  ATI06008.1  746 aa TonB-dependent siderophore receptor 3.3e-6 ●○○○○ -0.5 -0.503789613182284
Escherichia coli M12  CO715_21710  ATI08113.1  1265 aa molybdate metabolism regulator 7.5e-6 ●○○○○ -0.5 -0.503372321153786
Escherichia coli M12  CO715_12965  ATI06538.1  92 aa transcriptional regulator 1.1e-6 ●○○○○ -0.5 -0.50253773709679
Escherichia coli M12  CO715_16500  ATI07174.1  443 aa MFS transporter 8.4e-10 ●○○○○ -0.5 -0.502329091082542
Escherichia coli M12  CO715_22045  ATI08177.1  426 aa colanic acid biosynthesis pyruvyl transferase WcaK 5.1e-20 ●○○○○ -0.5 -0.501703153039795
Escherichia coli M12  CO715_02180  ATI04644.1  135 aa PTS sorbose transporter subunit IIA 1.7e-7 ●○○○○ -0.5 -0.499825338911555
Escherichia coli M12  CO715_21880  ATI08146.1  471 aa MFS transporter 2.4e-9 ●○○○○ -0.5 -0.49899075485456
Escherichia coli M12  CO715_10250  ATI06046.1  823 aa exonuclease 6.4e-8 ●○○○○ -0.5 -0.49899075485456
Escherichia coli M12  CO715_21220  ATI08024.1  149 aa periplasmic nitrate reductase electron transfer subunit 5.3e-19 ●○○○○ -0.5 -0.498156170797564
Escherichia coli M12  CO715_18065  ATI07454.1  298 aa LysR family transcriptional regulator 4.5e-9 ●○○○○ -0.5 -0.497947524783315
Escherichia coli M12  CO715_17745  ATI07399.1  315 aa YscQ/HrcQ family type III secretion apparatus protein 5.0e-209 ●○○○○ -0.5 -0.497530232754818
Escherichia coli M12  CO715_10000  ATI06011.1  232 aa phage minor tail protein L 0.015 ●○○○○ -0.5 -0.49711294072632
Escherichia coli M12  CO715_08790  ATI05802.1  760 aa TonB-dependent siderophore receptor 1.7e-17 ●○○○○ -0.5 -0.496904294712071
Escherichia coli M12  CO715_14750  ATI06861.1  369 aa branched chain amino acid ABC transporter substrate-binding protein 1.0e-20 ●○○○○ -0.49 -0.493774604498338
Escherichia coli M12  CO715_02705  ATI04742.1  479 aa hydrogenase-4 component D 4.2e-18 ●○○○○ -0.49 -0.492522728412845
Escherichia coli M12  CO715_01695  ATI04556.1  500 aa proline/betaine transporter 5.1e-6 ●○○○○ -0.49 -0.491896790370098
Escherichia coli M12  CO715_08565  ATI05762.1  410 aa multidrug transporter MdfA 1.2e-19 ●○○○○ -0.49 -0.490227622256107
Escherichia coli M12  CO715_21090  ATI08002.1  413 aa MFS transporter 7.3e-11 ●○○○○ -0.49 -0.486889286028126
Escherichia coli M12  CO715_13540  ATI06638.1  187 aa hypothetical protein 0.00052 ●○○○○ -0.49 -0.486680640013877
Escherichia coli M12  CO715_00815  ATI04403.1  142 aa heat-shock protein IbpB 0.0057 ●○○○○ -0.49 -0.485428763928384
Escherichia coli M12  CO715_12295  ATI06417.1  201 aa L(+)-tartrate dehydratase subunit beta 4.2e-47 ●○○○○ -0.49 -0.485220117914135
Escherichia coli M12  CO715_20505  ATI07895.1  418 aa hypothetical protein 1.1e-104 ●○○○○ -0.48 -0.484176887842891
Escherichia coli M12  CO715_13070  ATI06557.1  217 aa glutamine amidotransferase 0.025 ●○○○○ -0.48 -0.483759595814393
Escherichia coli M12  CO715_10595  ATI06107.1  424 aa tyrosine--tRNA ligase 0.0025 ●○○○○ -0.48 -0.481881781686153
Escherichia coli M12  CO715_01900  ATI04592.1  104 aa hypothetical protein 6.4e-15 ●○○○○ -0.48 -0.481255843643407
Escherichia coli M12  CO715_05220  ATI05181.1  221 aa YecA family protein 4.1e-14 ●○○○○ -0.48 -0.477917507415425
Escherichia coli M12  CO715_07300  ATI05538.1  70 aa cold-shock protein CspG 7.8e-11 ●○○○○ -0.48 -0.477708861401176
Escherichia coli M12  CO715_18230  ATI07484.1  663 aa transketolase 2.4e-10 ●○○○○ -0.48 -0.477500215386927
Escherichia coli M12  CO715_22190  ATI08202.1  367 aa UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase 0.0001 ●○○○○ -0.48 -0.476456985315683
Escherichia coli M12  CO715_09755  ATI05968.1  262 aa hydrolase 2.9e-9 ●○○○○ -0.48 -0.475205109230189
Escherichia coli M12  CO715_13290  ATI06596.1  646 aa RNase E specificity factor CsrD 2.2e-18 ●○○○○ -0.47 -0.474579171187443
Escherichia coli M12  CO715_07280  ATI05535.1  357 aa electron transporter YccM 1.6e-8 ●○○○○ -0.47 -0.471866773002208
Escherichia coli M12  CO715_19920  ATI07785.1  272 aa HMP-PP phosphatase 0.036 ●○○○○ -0.47 -0.468945728802724
Escherichia coli M12  CO715_03140  ATI04818.1  415 aa PTS fructose transporter subunit IIC 0.0022 ●○○○○ -0.47 -0.467067914674484
Escherichia coli M12  CO715_18575  ATI07544.1  559 aa peptide ABC transporter substrate-binding protein 8.4e-5 ●○○○○ -0.47 -0.466441976631737
Escherichia coli M12  CO715_23755  ATI08457.1  482 aa two-component sensor histidine kinase 0.00016 ●○○○○ -0.47 -0.466233330617489
Escherichia coli M12  CO715_21425  ATI08061.1  416 aa NupC/NupG family nucleoside CNT transporter 2.4e-18 ●○○○○ -0.47 -0.465190100546244
Escherichia coli M12  CO715_04270  ATI05029.1  179 aa stationary phase growth adaptation protein 5.4e-6 ●○○○○ -0.47 -0.465190100546244
Escherichia coli M12  CO715_22695  ATI08286.1  214 aa hypothetical protein 2.8e-21 ●○○○○ -0.46 -0.464355516489249
Escherichia coli M12  CO715_22955  ATI08333.1  85 aa DUF3343 domain-containing protein 2.1e-117 ●○○○○ -0.46 -0.462894994389507
Escherichia coli M12  CO715_11470  ATI06269.1  536 aa BCCT family transporter 7.4e-17 ●○○○○ -0.46 -0.461851764318263
Escherichia coli M12  CO715_10975  ATI06175.1  237 aa EAL domain-containing protein 2.8e-29 ●○○○○ -0.46 -0.461434472289765
Escherichia coli M12  CO715_23875  ATI08480.1  477 aa glycogen synthase 1.1e-25 ●○○○○ -0.46 -0.461225826275516
Escherichia coli M12  CO715_07870  ATI05635.1  358 aa hypothetical protein 1.2e-59 ●○○○○ -0.46 -0.459973950190023
Escherichia coli M12  CO715_22740  ATI08295.1  260 aa metal-dependent hydrolase 2.0e-11 ●○○○○ -0.46 -0.459973950190023
Escherichia coli M12  CO715_12080  ATI06381.1  407 aa glycolate oxidase iron-sulfur subunit 0.0016 ●○○○○ -0.46 -0.459765304175774
Escherichia coli M12  CO715_05690  ATI05263.1  605 aa DNA primase 6.2e-19 ●○○○○ -0.46 -0.459348012147276
Escherichia coli M12  CO715_07145  ATI05512.1  217 aa 23S rRNA pseudouridine(2457) synthase RluE 7.7e-6 ●○○○○ -0.46 -0.459348012147276
Escherichia coli M12  CO715_22650  ATI08280.1  215 aa phosphoglycerate mutase GpmB 0.026 ●○○○○ -0.45 -0.454340507805303
Escherichia coli M12  CO715_18830  ATI07590.1  243 aa laccase domain-containing protein 0.0036 ●○○○○ -0.45 -0.452671339691313
Escherichia coli M12  CO715_20700  ATI07929.1  110 aa curli assembly protein CsgC 3.5e-20 ●○○○○ -0.45 -0.452462693677064
Escherichia coli M12  CO715_00425  ATI04332.1  271 aa AraC family transcriptional regulator 0.00011 ●○○○○ -0.45 -0.452254047662815
Escherichia coli M12  CO715_12300  ATI06418.1  487 aa anion permease 6.8e-14 ●○○○○ -0.45 -0.450167587520326
Escherichia coli M12  CO715_19165  ATI07649.1  286 aa oxidoreductase 8.4e-15 ●○○○○ -0.45 -0.449750295491828
Escherichia coli M12  CO715_10970  ATI06174.1  478 aa SELO family protein 1.2e-41 ●○○○○ -0.45 -0.448707065420584
Escherichia coli M12  CO715_01225  ATI04473.1  91 aa DUF1471 domain-containing protein 3.1e-5 ●○○○○ -0.45 -0.448081127377838
Escherichia coli M12  CO715_11430  ATI06263.1  32 aa hypothetical protein 0.00099 ●○○○○ -0.44 -0.443699561078612
Escherichia coli M12  CO715_09315  ATI05892.1  188 aa type 1 fimbrial protein 6.5e-27 ●○○○○ -0.44 -0.442447684993118
Escherichia coli M12  CO715_20815  ATI07950.1  402 aa multidrug resistance protein MdtH 0.009 ●○○○○ -0.44 -0.440987162893376
Escherichia coli M12  CO715_07825  ATI05627.1  265 aa DNA-binding protein 6.7e-5 ●○○○○ -0.44 -0.440569870864879
Escherichia coli M12  CO715_05195  ATI05179.1  610 aa excinuclease ABC subunit C 0.00011 ●○○○○ -0.44 -0.439735286807883
Escherichia coli M12  CO715_22730  ATI08293.1  516 aa YjjI family glycine radical enzyme 6.9e-7 ●○○○○ -0.44 -0.43848341072239
Escherichia coli M12  CO715_04465  ATI05056.1  238 aa YebC/PmpR family DNA-binding transcriptional regulator 6.6e-8 ●○○○○ -0.44 -0.438066118693892
Escherichia coli M12  CO715_07095  ATI05502.1  261 aa phage recombination protein Bet 1.4e-16 ●○○○○ -0.44 -0.43660559659415
Escherichia coli M12  CO715_05845  ATI05287.1  223 aa tail assembly protein 0.041 ●○○○○ -0.44 -0.43660559659415
Escherichia coli M12  CO715_01605  ATI04541.1  90 aa N-acetyltransferase 0.007 ●○○○○ -0.43 -0.434101844423164
Escherichia coli M12  CO715_14405  ATI06794.1  27 aa Damage inducible protein 0.0026 ●○○○○ -0.43 -0.433475906380417
Escherichia coli M12  CO715_12475  ATI06449.1  495 aa altronate dehydratase 1.1e-17 ●○○○○ -0.43 -0.432015384280675
Escherichia coli M12  CO715_11910  ATI06350.1  294 aa NAD(P)-dependent oxidoreductase 3.4e-8 ●○○○○ -0.43 -0.432015384280675
Retrieved entries 1,501–1,600 out of 3,550 total in 51 ms (Link to these results)