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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_13365  ATI06610.1  385 aa MexX family efflux pump subunit 6.7e-35 ●○○○○ -0.11 -0.111743752408673
Escherichia coli M12  CO715_00775  ATI04396.1  149 aa hypothetical protein 0.039 ●○○○○ -0.11 -0.10861406219494
Escherichia coli M12  CO715_08905  ATI05823.1  161 aa cyclic pyranopterin monophosphate synthase MoaC 0.028 ●○○○○ -0.11 -0.106527602052452
Escherichia coli M12  CO715_20820  ATI07951.1  194 aa 30S ribosomal protein S5 alanine N-acetyltransferase 4.5e-10 ●○○○○ -0.11 -0.106318956038203
Escherichia coli M12  CO715_17225  ATI07305.1  191 aa glycerol uptake operon antiterminator 0.0065 ●○○○○ -0.11 -0.105484371981207
Escherichia coli M12  CO715_14210  ATI06758.1  844 aa penicillin-binding protein 1B 0.00039 ●○○○○ -0.11 -0.10506707995271
Escherichia coli M12  CO715_14205  ATI06757.1  752 aa ferrichrome porin FhuA 1.2e-18 ●○○○○ -0.1 -0.104232495895714
Escherichia coli M12  CO715_04750  ATI05106.1  552 aa flagellar M-ring protein FliF 0.014 ●○○○○ -0.1 -0.104023849881465
Escherichia coli M12  CO715_08225  ATI05700.1  476 aa amino acid permease 5.4e-75 ●○○○○ -0.1 -0.103606557852968
Escherichia coli M12  CO715_09865  ATI05987.1  300 aa LysR family transcriptional regulator 3.1e-79 ●○○○○ -0.1 -0.102563327781723
Escherichia coli M12  CO715_05935  ATI05299.1  346 aa peptidase S74 5.0e-20 ●○○○○ -0.1 -0.100685513653484
Escherichia coli M12  CO715_11035  ATI06187.1  632 aa hypothetical protein 3.0e-148 ●○○○○ -0.1 -0.0998509295964882
Escherichia coli M12  CO715_13880  ATI06700.1  286 aa NAD(P)-dependent oxidoreductase 2.2e-25 ●○○○○ -0.1 -0.0979731154682485
Escherichia coli M12  CO715_17245  ATI07309.1  484 aa FAD-binding oxidoreductase 2.0e-18 ●○○○○ -0.09 -0.0927569651120269
Escherichia coli M12  CO715_19220  ATI07660.1  311 aa tRNA 2-thiocytidine(32) synthetase TtcA 1.7e-14 ●○○○○ -0.09 -0.0894186288840451
Escherichia coli M12  CO715_01635  ATI04546.1  548 aa fumarate hydratase 0.016 ●○○○○ -0.09 -0.0890013368555474
Escherichia coli M12  CO715_12805  ATI06510.1  335 aa LLM class flavin-dependent oxidoreductase 0.00013 ●○○○○ -0.09 -0.0883753988128008
Escherichia coli M12  CO715_03400  ATI04865.1  174 aa fimbrial protein 0.0053 ●○○○○ -0.09 -0.0883753988128008
Escherichia coli M12  CO715_23950  ATI08493.1  408 aa RtcB family protein 2.7e-7 ●○○○○ -0.09 -0.0879581067843031
Escherichia coli M12  CO715_15335  ATI06965.1  104 aa L-rhamnose mutarotase 4.6e-5 ●○○○○ -0.09 -0.0864975846845611
Escherichia coli M12  CO715_15730  ATI07031.1  413 aa uroporphyrinogen-III C-methyltransferase 0.003 ●○○○○ -0.09 -0.0858716466418145
Escherichia coli M12  CO715_00695  ATI04380.1  439 aa MFS transporter family glucose-6-phosphate receptor UhpC 0.02 ●○○○○ -0.08 -0.0844111245420724
Escherichia coli M12  CO715_22920  ATI08327.1  113 aa endoribonuclease SymE 1.3e-13 ●○○○○ -0.08 -0.0837851864993259
Escherichia coli M12  CO715_12240  ATI06409.1  361 aa dTDP-glucose 4,6-dehydratase 0.0039 ●○○○○ -0.08 -0.0823246643995839
Escherichia coli M12  CO715_13225  ATI06584.1  655 aa p-hydroxybenzoic acid efflux pump subunit AaeB 1.5e-21 ●○○○○ -0.08 -0.082116018385335
Escherichia coli M12  CO715_18915  ATI07605.1  700 aa TonB-dependent siderophore receptor 0.00012 ●○○○○ -0.08 -0.0819073723710861
Escherichia coli M12  CO715_24620  ATI08611.1  383 aa L-threonine dehydrogenase 4.2e-16 ●○○○○ -0.08 -0.080655496285593
Escherichia coli M12  CO715_08965  ATI05835.1  427 aa acyl-CoA thioesterase 1.7e-16 ●○○○○ -0.08 -0.0804468502713441
Escherichia coli M12  CO715_20890  ATI07965.1  365 aa flagellar biosynthesis protein FlgA 0.037 ●○○○○ -0.08 -0.0798209122285975
Escherichia coli M12  CO715_22505  ATI08257.1  327 aa dipeptide transport ATP-binding protein DppD 3.0e-23 ●○○○○ -0.08 -0.0783603901288555
Escherichia coli M12  CO715_08885  ATI05819.1  129 aa hypothetical protein 6.5e-6 ●○○○○ -0.08 -0.07752580607186
Escherichia coli M12  CO715_06690  ATI05429.1  356 aa alanine racemase 5.0e-5 ●○○○○ -0.08 -0.0768998680291135
Escherichia coli M12  CO715_10630  ATI06112.1  285 aa efflux transporter periplasmic adaptor subunit 0.0016 ●○○○○ -0.08 -0.0764825760006157
Escherichia coli M12  CO715_08570  ATI05763.1  198 aa undecaprenyl-diphosphate phosphatase 2.0e-5 ●○○○○ -0.08 -0.0750220539008737
Escherichia coli M12  CO715_04585  ATI05077.1  334 aa mononuclear molybdenum enzyme YedY 2.3e-56 ●○○○○ -0.07 -0.074604761872376
Escherichia coli M12  CO715_01615  ATI04543.1  543 aa sensor histidine kinase 1.7e-12 ●○○○○ -0.07 -0.0743961158581272
Escherichia coli M12  CO715_07110  ATI05505.1  63 aa hypothetical protein 1.3e-9 ●○○○○ -0.07 -0.0743961158581272
Escherichia coli M12  CO715_11935  ATI06354.1  95 aa hypothetical protein 7.4e-13 ●○○○○ -0.07 -0.0708491336158965
Escherichia coli M12  CO715_17180  ATI07297.1  899 aa CRISPR-associated helicase/endonuclease Cas3 1.3e-24 ●○○○○ -0.07 -0.0704318415873988
Escherichia coli M12  CO715_15185  ATI06939.1  79 aa hypothetical protein 0.021 ●○○○○ -0.07 -0.070014549558901
Escherichia coli M12  CO715_12685  ATI06486.1  259 aa PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC 9.6e-8 ●○○○○ -0.07 -0.0687626734734079
Escherichia coli M12  CO715_17770  ATI07404.1  381 aa YopN family type III secretion system gatekeeper subunit 1.7e-70 ●○○○○ -0.07 -0.0677194434021636
Escherichia coli M12  CO715_22985  ATI08338.1  390 aa isoaspartyl dipeptidase 1.8e-15 ●○○○○ -0.07 -0.0664675673166704
Escherichia coli M12  CO715_12170  ATI06398.1  392 aa type II secretion system protein GspL 2.0e-13 ●○○○○ -0.06 -0.0641724611599329
Escherichia coli M12  CO715_08420  ATI05733.1  600 aa hypothetical protein 2.9e-20 ●○○○○ -0.06 -0.0631292310886886
Escherichia coli M12  CO715_19775  ATI07758.1  624 aa molecular chaperone HtpG 0.009 ●○○○○ -0.06 -0.0602081868892046
Escherichia coli M12  CO715_00110  ATI04277.1  384 aa bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 5.7e-8 ●○○○○ -0.06 -0.059582248846458
Escherichia coli M12  CO715_23180  ATI08371.1  143 aa PTS sugar transporter subunit IIA 4.6e-7 ●○○○○ -0.06 -0.059582248846458
Escherichia coli M12  CO715_14790  ATI06869.1  356 aa sn-glycerol-3-phosphate import ATP-binding protein UgpC 0.017 ●○○○○ -0.06 -0.0593736028322091
Escherichia coli M12  CO715_12455  ATI06445.1  321 aa hypothetical protein 6.6e-6 ●○○○○ -0.06 -0.0587476647894625
Escherichia coli M12  CO715_04600  ATI05079.1  452 aa two-component sensor histidine kinase 7.2e-20 ●○○○○ -0.06 -0.0581217267467159
Escherichia coli M12  CO715_09040  ATI05850.1  348 aa galactose-1-phosphate uridylyltransferase 0.0014 ●○○○○ -0.06 -0.056452558632725
Escherichia coli M12  CO715_13960  ATI06713.1  235 aa tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO 0.038 ●○○○○ -0.06 -0.056452558632725
Escherichia coli M12  CO715_18895  ATI07601.1  205 aa glutathione S-transferase family protein 2.1e-14 ●○○○○ -0.05 -0.0547833905187341
Escherichia coli M12  CO715_01260  ATI04480.1  354 aa L-ascorbate-6-phosphate lactonase 3.5e-13 ●○○○○ -0.05 -0.0543660984902365
Escherichia coli M12  CO715_07270  ATI05534.1  342 aa TMAO reductase system periplasmic protein TorT 0.0002 ●○○○○ -0.05 -0.0526969303762456
Escherichia coli M12  CO715_16930  ATI07252.1  746 aa carbamoyltransferase HypF 4.5e-10 ●○○○○ -0.05 -0.0518623463192501
Escherichia coli M12  CO715_17675  ATI07387.1  210 aa LuxR family transcriptional regulator 1.3e-13 ●○○○○ -0.05 -0.0512364082765035
Escherichia coli M12  CO715_06220  ATI05350.1  187 aa fimbrial protein 1.6e-17 ●○○○○ -0.05 -0.0508191162480058
Escherichia coli M12  CO715_22840  ATI08312.1  763 aa phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase 1.6e-15 ●○○○○ -0.05 -0.0508191162480058
Escherichia coli M12  CO715_21780  ATI08127.1  272 aa hypothetical protein 2.2e-5 ●○○○○ -0.05 -0.0481067180627706
Escherichia coli M12  CO715_10475  ATI06085.1  457 aa MFS transporter 3.6e-64 ●○○○○ -0.05 -0.0476894260342729
Escherichia coli M12  CO715_15255  ATI06951.1  199 aa glucose-1-phosphatase 8.8e-8 ●○○○○ -0.05 -0.0476894260342729
Escherichia coli M12  CO715_01700  ATI04557.1  292 aa hypothetical protein 2.0e-5 ●○○○○ -0.05 -0.0474807800200241
Escherichia coli M12  CO715_21115  ATI08007.1  419 aa anaerobic glycerol-3-phosphate dehydrogenase subunit B 0.019 ●○○○○ -0.05 -0.0474807800200241
Escherichia coli M12  CO715_01200  ATI04468.1  264 aa DUF2686 domain-containing protein 3.7e-39 ●○○○○ -0.05 -0.0464375499487797
Escherichia coli M12  CO715_17355  ATI07329.1  282 aa NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 9.0e-17 ●○○○○ -0.05 -0.0464375499487797
Escherichia coli M12  CO715_09230  ATI05877.1  105 aa DUF4387 domain-containing protein 4.1e-10 ●○○○○ -0.05 -0.0458116119060332
Escherichia coli M12  CO715_14550  ATI06823.1  314 aa nickel ABC transporter permease subunit NikB 0.044 ●○○○○ -0.04 -0.0441424437920423
Escherichia coli M12  CO715_05650  ATI08737.1  89 aa capsid protein 2.1e-5 ●○○○○ -0.04 -0.0433078597350468
Escherichia coli M12  CO715_00835  ATI08698.1  366 aa colicin M resistance protein CbrA 2.0e-5 ●○○○○ -0.04 -0.0426819216923002
Escherichia coli M12  CO715_17560  ATI07366.1  719 aa bifunctional 2-acylglycerophosphoethanolamine acyltransferase/acyl-ACP synthetase 2.7e-22 ●○○○○ -0.04 -0.0422646296638025
Escherichia coli M12  CO715_12590  ATI06470.1  443 aa threonine/serine transporter TdcC 6.7e-36 ●○○○○ -0.04 -0.0418473376353048
Escherichia coli M12  CO715_23520  ATI08418.1  225 aa iron export ATP-binding protein FetA 6.7e-23 ●○○○○ -0.04 -0.0418473376353048
Escherichia coli M12  CO715_12255  ATI06412.1  183 aa dTDP-4-dehydrorhamnose 3,5-epimerase 0.019 ●○○○○ -0.04 -0.0401781695213139
Escherichia coli M12  CO715_15840  ATI08832.1  609 aa DNA helicase RecQ 8.1e-30 ●○○○○ -0.04 -0.0378830633645764
Escherichia coli M12  CO715_11675  ATI06305.1  946 aa glutamine-synthetase adenylyltransferase 5.5e-11 ●○○○○ -0.04 -0.0376744173503276
Escherichia coli M12  CO715_22210  ATI08206.1  355 aa dTDP-glucose 4,6-dehydratase 7.3e-6 ●○○○○ -0.04 -0.0374657713360787
Escherichia coli M12  CO715_04900  ATI05129.1  547 aa multidrug ABC transporter permease/ATP-binding protein 4.6e-39 ●○○○○ -0.04 -0.0370484793075809
Escherichia coli M12  CO715_04005  ATI04977.1  252 aa phosphoglycolate phosphatase 7.9e-10 ●○○○○ -0.03 -0.0335014970653503
Escherichia coli M12  CO715_01140  ATI04460.1  498 aa ATPase RavA 4.6e-6 ●○○○○ -0.03 -0.0291199307661243
Escherichia coli M12  CO715_18495  ATI07531.1  325 aa protein CsiD 2.0e-6 ●○○○○ -0.03 -0.0287026387376265
Escherichia coli M12  CO715_11375  ATI06252.1  427 aa hypothetical protein 0.0015 ●○○○○ -0.03 -0.0259902405523913
Escherichia coli M12  CO715_24525  ATI08596.1  93 aa hypothetical protein 0.00072 ●○○○○ -0.02 -0.024947010481147
Escherichia coli M12  CO715_17280  ATI07316.1  382 aa hypothetical protein 4.9e-5 ●○○○○ -0.02 -0.0245297184526493
Escherichia coli M12  CO715_13325  ATI06603.1  483 aa sodium/panthothenate symporter 3.0e-6 ●○○○○ -0.02 -0.0241124264241516
Escherichia coli M12  CO715_18095  ATI07459.1  714 aa methylmalonyl-CoA mutase 2.2e-8 ●○○○○ -0.02 -0.0236951343956538
Escherichia coli M12  CO715_01965  ATI04605.1  940 aa excinuclease ABC subunit A 1.7e-24 ●○○○○ -0.02 -0.0222346122959119
Escherichia coli M12  CO715_01670  ATI04552.1  445 aa arginine:agmatine antiporter 0.029 ●○○○○ -0.02 -0.0176443999824369
Escherichia coli M12  CO715_04590  ATI05078.1  137 aa 5-hydroxyisourate hydrolase 0.0074 ●○○○○ -0.02 -0.0166011699111926
Escherichia coli M12  CO715_02095  ATI04629.1  396 aa maltose/maltodextrin ABC transporter substrate-binding protein MalE 0.02 ●○○○○ -0.02 -0.0163925238969437
Escherichia coli M12  CO715_06265  ATI05358.1  560 aa sulfatase 1.8e-8 ●○○○○ -0.01 -0.012845541654713
Escherichia coli M12  CO715_00785  ATI04398.1  571 aa solute:sodium symporter family transporter 9.0e-24 ●○○○○ -0.01 -0.0120109575977176
Escherichia coli M12  CO715_21845  ATI08139.1  299 aa lipid kinase YegS 1.1e-30 ●○○○○ -0.01 -0.0103417894837267
Escherichia coli M12  CO715_00450  ATI04336.1  328 aa TRAP transporter substrate-binding protein 2.0e-32 ●○○○○ -0.01 -0.00867262136973579
Escherichia coli M12  CO715_13640  ATI06656.1  503 aa cytosol aminopeptidase 1.0e-5 ●○○○○ -0.01 -0.00825532934123812
Escherichia coli M12  CO715_06495  ATI05395.1  35 aa small toxic polypeptide LdrA/LdrC 5.6e-5 ●○○○○ -0.01 -0.00804668332698928
Escherichia coli M12  CO715_22155  ATI08195.1  494 aa guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase 3.5e-9 ●○○○○ -0.01 -0.00658616122724723
Escherichia coli M12  CO715_17830  ATI07412.1  396 aa knotted carbamoyltransferase YgeW 4.2e-47 ●○○○○ -0.01 -0.00512563912750517
Escherichia coli M12  CO715_10585  ATI06105.1  201 aa glutathione S-transferase n.s. ●●○○○ -1.4 -1.40388851865187
Retrieved entries 1,901–2,000 out of 3,550 total in 45.9 ms (Link to these results)