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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0013  CBW16114.1  A0A0H3N7I0  dnaJ  379 aa DnaJ protein 0.0047 ●●○○○ -1.39 -1.39291398310347
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1712  CBW17807.1  A0A0H3NC19  ychF  363 aa hypothetical ATP/GTP-binding protein 0.011 ●●○○○ -1.39 -1.39275749612285
Mycobacterium avium subsp. paratuberculosis K10  MAP_2370c  AAS04687.1  Q73XD9  274 aa hypothetical protein 0.05 ●●○○○ -1.39 -1.39224009209053
Escherichia coli M12  CO715_10540  ATI06097.1  193 aa electron transport complex subunit A 1.3e-37 ●●○○○ -1.39 -1.39220434185393
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2246  WP_000598637.1  E8XCZ9  yehT  239 aa two-component system response regulator BtsR 1.2e-17 ●●○○○ -1.39 -1.39216263064841
Porphyromonas gingivalis ATCC 33277  PGN_0033  WP_004583434.1  B2RGQ7  104 aa thioredoxin <1e-323 ●●○○○ -1.39 -1.3921230333054
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3080  AIK81665.1  309 aa homoserine O-succinyltransferase <1e-323 ●●○○○ -1.39 -1.3920040404547
Escherichia coli M12  CO715_09225  ATI05876.1  456 aa 3-methylaspartate ammonia-lyase 6.4e-30 ●●○○○ -1.39 -1.39199569583969
Escherichia coli M12  CO715_20135  ATI07827.1  375 aa tRNA guanosine(34) transglycosylase Tgt 3.8e-19 ●●○○○ -1.39 -1.39178704982544
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1035  WP_000877926.1  E8XDJ8  sodC1  177 aa superoxide dismutase [Cu-Zn] 3.0e-9 ●●○○○ -1.39 -1.39168363344379
Escherichia coli M12  CO715_07405  ATI05556.1  148 aa hypothetical protein 4.1e-26 ●●○○○ -1.39 -1.39157840381119
Escherichia coli M12  CO715_18700  ATI07566.1  160 aa SsrA-binding protein 3.1e-25 ●●○○○ -1.39 -1.39157840381119
Mycobacterium avium subsp. paratuberculosis K10  MAP_0602  AAS02919.1  Q743I3  aldA  489 aa AldA_1 0.05 ●●○○○ -1.39 -1.39155146482262
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1405  NP_231048.2  Q9KS55  563 aa methyl-accepting chemotaxis protein 2.6e-10 ●●○○○ -1.39 -1.39139026751506
Escherichia coli M12  CO715_05160  ATI05172.1  266 aa cystine ABC transporter substrate-binding protein 8.4e-16 ●●○○○ -1.39 -1.39136975779694
Escherichia coli M12  CO715_14165  ATI06749.1  266 aa cobalamin-binding protein 1.9e-8 ●●○○○ -1.39 -1.39095246576844
Acinetobacter baumannii ATCC 17978  A1S_2315  ABO12737.2  380 aa EsvE3 5.8e-8 ●●○○○ -1.39 -1.39068999568967
Mycobacterium avium subsp. paratuberculosis K10  MAP_0254c  AAS02571.1  Q745P1  104 aa hypothetical protein 0.05 ●●○○○ -1.39 -1.39007682747029
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1230  CBW17326.1  A0A0H3NCD8  sppA  618 aa protease IV 0.013 ●●○○○ -1.39 -1.38948071035368
Escherichia coli M12  CO715_18965  ATI07612.1  269 aa acetyltransferase 2.5e-15 ●●○○○ -1.39 -1.38928329765445
Escherichia coli M12  CO715_00145  ATI04283.1  71 aa hypothetical protein 5.2e-56 ●●○○○ -1.39 -1.3890746516402
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3493  CBW19587.1  A0A0H3NH09  glpD  502 aa aerobic glycerol-3-phosphate dehydrogenase 0.019 ●●○○○ -1.39 -1.38858682702153
Acinetobacter baumannii ATCC 17978  A1S_2026  ABO12453.1  75 aa hypothetical protein 0.025 ●●○○○ -1.39 -1.38789776079386
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0145  WP_001286419.1  E8XH49  yacG  63 aa DNA gyrase inhibitor YacG 1.8e-8 ●●○○○ -1.39 -1.38733122299979
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0039  CBW16140.1  A0A0H3NH03  571 aa possible sulfatase 0.0019 ●●○○○ -1.39 -1.38689651808579
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2090  NP_231722.1  Q9KQB0  114 aa succinate dehydrogenase hydrophobic membrane anchor protein 1.6e-8 ●●○○○ -1.39 -1.38630621094148
Escherichia coli M12  CO715_20930  ATI07973.1  319 aa ribosomal large subunit pseudouridine synthase C 5.5e-23 ●●○○○ -1.39 -1.38594496142647
Acinetobacter baumannii ATCC 17978  A1S_1099  ABO11529.2  452 aa D-glucarate/D-galactarate permease (MFS superfamily) 1.4e-16 ●●○○○ -1.39 -1.38572325409751
Escherichia coli M12  CO715_16675  ATI07206.1  220 aa transcriptional regulator 1.5e-7 ●●○○○ -1.39 -1.38531902338372
Escherichia coli M12  CO715_14415  ATI06796.1  280 aa 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ 1.5e-15 ●●○○○ -1.38 -1.38323256324123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3631  AIK82187.1  185 aa putative periplasmic protein <1e-323 ●●○○○ -1.38 -1.38300357525479
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1847  NP_231481.1  Q9KR00  ruvC  173 aa Holliday junction resolvase 9.8e-6 ●●○○○ -1.38 -1.38267189011671
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4697  AIK83231.1  156 aa thiol peroxidase 2.5e-13 ●●○○○ -1.38 -1.3821924546449
Escherichia coli M12  CO715_02480  ATI04699.1  229 aa tRNA (guanosine(18)-2'-O)-methyltransferase TrmH 1.1e-12 ●●○○○ -1.38 -1.38114610309875
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4786  AIK83313.1  253 aa mlaA <1e-323 ●●○○○ -1.38 -1.38057863613742
Escherichia coli M12  CO715_04435  ATI05053.1  305 aa nitrogen assimilation regulatory protein nac 8.3e-14 ●●○○○ -1.38 -1.380520165056
Escherichia coli M12  CO715_07225  ATI05527.1  273 aa NAD-dependent deacylase 5.8e-5 ●●○○○ -1.38 -1.3801028730275
Escherichia coli M12  CO715_20740  ATI07935.1  847 aa glucans biosynthesis glucosyltransferase MdoH 2.0e-26 ●●○○○ -1.38 -1.37885099694201
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1222  WP_000799391.1  E8XFF2  potB  287 aa spermidine/putrescine ABC transporter permease PotB 3.3e-9 ●●○○○ -1.38 -1.3781996749726
Escherichia coli M12  CO715_04800  ATI05111.1  137 aa hypothetical protein 1.1e-22 ●●○○○ -1.38 -1.37780776687076
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0309  NP_229964.1  Q9KV48  ubiD  613 aa hypothetical protein 1.8e-9 ●●○○○ -1.38 -1.37774162538955
Porphyromonas gingivalis ATCC 33277  PGN_0757  WP_012457756.1  B2RIT1  208 aa HAD family phosphatase 0.00033 ●●○○○ -1.38 -1.37757079872862
Escherichia coli M12  CO715_21950  ATI08159.1  617 aa outer membrane assembly protein AsmA 2.0e-8 ●●○○○ -1.38 -1.37676453679952
Escherichia coli M12  CO715_21265  ATI08033.1  350 aa cytochrome c biogenesis protein CcmH 7.9e-7 ●●○○○ -1.38 -1.37634724477102
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0022  WP_000743357.1  E8XG42  bcfA  180 aa fimbrial protein BcfA 6.1e-8 ●●○○○ -1.38 -1.37570492184021
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4505  CBW20594.1  A0A0H3NJB3  serB  322 aa hypothetical phosphoserine phosphatase 0.0061 ●●○○○ -1.38 -1.37525364525016
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4712  WP_000683247.1  E8XCF4  244 aa aspartate/glutamate racemase family protein 0.012 ●●○○○ -1.38 -1.37511312532336
Escherichia coli M12  CO715_13590  ATI06647.1  339 aa aldehyde reductase Ahr 1.4e-5 ●●○○○ -1.37 -1.37467807665703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3459  AIK82015.1  81 aa cell division factor ZapB <1e-323 ●●○○○ -1.37 -1.37394586649902
Escherichia coli M12  CO715_10765  ATI06136.1  270 aa hypothetical protein 2.3e-42 ●●○○○ -1.37 -1.37342620057154
Escherichia coli M12  CO715_15920  ATI07066.1  171 aa twin-arginine translocase subunit TatB 1.4e-5 ●●○○○ -1.37 -1.37342620057154
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2933  WP_000022009.1  E8XK39  ygaP  175 aa DUF2892 domain-containing protein 0.0053 ●●○○○ -1.37 -1.37334933051262
Acinetobacter baumannii ATCC 17978  A1S_2166  ABO12593.2  350 aa cytochrome o ubiquinol oxidase subunit II 0.00019 ●●○○○ -1.37 -1.37231683267416
Escherichia coli M12  CO715_04645  ATI05087.1  305 aa hypothetical protein 3.6e-21 ●●○○○ -1.37 -1.37175703245755
Escherichia coli M12  CO715_05115  ATI05164.1  124 aa toxin CbtA 3.6e-13 ●●○○○ -1.37 -1.3715483864433
Escherichia coli M12  CO715_06625  ATI05417.1  326 aa iron ABC transporter permease 6.4e-8 ●●○○○ -1.37 -1.37133974042905
Escherichia coli M12  CO715_16195  ATI07116.1  400 aa type IV pilin biogenesis protein 1.1e-14 ●●○○○ -1.37 -1.37092244840055
Escherichia coli M12  CO715_09710  ATI05959.1  362 aa endolytic peptidoglycan transglycosylase RlpA 1.5e-14 ●●○○○ -1.37 -1.37092244840055
Porphyromonas gingivalis ATCC 33277  PGN_1941  WP_039416603.1  B2RM65  289 aa deoxyribose-phosphate aldolase <1e-323 ●●○○○ -1.37 -1.37077731218988
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1340  NP_230984.1  Q9KSB8  632 aa prpE protein 9.7e-11 ●●○○○ -1.37 -1.37069019539214
Escherichia coli M12  CO715_06350  ATI08747.1  543 aa oligopeptide ABC transporter substrate-binding protein OppA 4.9e-30 ●●○○○ -1.37 -1.37050515637205
Escherichia coli M12  CO715_02985  ATI04793.1  365 aa sulfate/thiosulfate import ATP-binding protein CysA 0.00045 ●●○○○ -1.37 -1.37050515637205
Escherichia coli M12  CO715_06365  ATI05375.1  891 aa bifunctional acetaldehyde-CoA/alcohol dehydrogenase 4.9e-54 ●●○○○ -1.37 -1.36967057231506
Escherichia coli M12  CO715_15295  ATI06958.1  309 aa formate dehydrogenase accessory protein FdhE 0.00014 ●●○○○ -1.37 -1.36967057231506
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3530  WP_001253500.1  E8XD73  yhdP  1266 aa AsmA2 domain-containing protein 0.0046 ●●○○○ -1.37 -1.36922555616488
Escherichia coli M12  CO715_17420  ATI07342.1  131 aa hypothetical protein 2.6e-10 ●●○○○ -1.37 -1.36862734224381
Escherichia coli M12  CO715_00035  ATI04262.1  246 aa tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ 0.0052 ●●○○○ -1.37 -1.36800140420107
Escherichia coli M12  CO715_11230  ATI06224.1  216 aa sulfate ABC transporter ATP-binding protein 0.00032 ●●○○○ -1.37 -1.36779275818682
Escherichia coli M12  CO715_19080  ATI07633.1  307 aa LysR family transcriptional regulator 1.8e-28 ●●○○○ -1.37 -1.36695817412982
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4489  WP_000919289.1  E8X9U4  yjdB  547 aa phosphoethanolamine transferase EptA 5.2e-8 ●●○○○ -1.37 -1.36665533621703
Escherichia coli M12  CO715_19945  ATI07790.1  623 aa peptidyl-prolyl cis-trans isomerase 2.2e-24 ●●○○○ -1.37 -1.36633223608708
Escherichia coli M12  CO715_02815  ATI04763.1  316 aa transaldolase 4.2e-44 ●●○○○ -1.37 -1.36612359007283
Escherichia coli M12  CO715_06945  ATI05473.1  181 aa terminase small subunit 1.0e-12 ●●○○○ -1.37 -1.36549765203008
Escherichia coli M12  CO715_14620  ATI06836.1  193 aa DNA gyrase subunit B 3.6e-22 ●●○○○ -1.36 -1.36487171398733
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1060  WP_000156453.1  E8XE25  lonH  586 aa Lon protease family protein 0.0012 ●●○○○ -1.36 -1.3642020669833
Escherichia coli M12  CO715_06590  ATI05411.1  356 aa dihydroxyacetone kinase subunit DhaK 4.4e-10 ●●○○○ -1.36 -1.36403712993034
Escherichia coli M12  CO715_23115  ATI08362.1  328 aa hypothetical protein 1.1e-8 ●●○○○ -1.36 -1.36361983790184
Escherichia coli M12  CO715_04725  ATI05101.1  375 aa flagellar hook-length control protein FliK 3.3e-5 ●●○○○ -1.36 -1.36111608573085
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0379  WP_001526309.1  E8XJR3  foxA  696 aa ferrioxamine B receptor FoxA 5.7e-6 ●●○○○ -1.36 -1.36090595359029
Escherichia coli M12  CO715_18110  ATI07462.1  492 aa acetyl-CoA hydrolase 3.4e-22 ●●○○○ -1.36 -1.36007285565961
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4112  AIK82658.1  249 aa short chain dehydrogenase family protein <1e-323 ●●○○○ -1.36 -1.35983862796318
Escherichia coli M12  CO715_00200  ATI04293.1  216 aa anti-sigma-E factor RseA 0.00011 ●●○○○ -1.36 -1.35965556363111
Escherichia coli M12  CO715_08535  ATI05756.1  125 aa hypothetical protein 2.0e-10 ●●○○○ -1.36 -1.35944691761686
Escherichia coli M12  CO715_02970  ATI04790.1  338 aa sulfate ABC transporter substrate-binding protein 0.037 ●●○○○ -1.36 -1.35861233355987
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3748  CBW19839.1  A0A0H3NJ84  452 aa PTS system, galactitol-specific IIC component 0.0065 ●●○○○ -1.36 -1.35832579003888
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0889  NP_233274.1  Q9KL59  312 aa LysR family transcriptional regulator 5.8e-7 ●●○○○ -1.36 -1.35824404682397
Acinetobacter baumannii ATCC 17978  A1S_0143  ABO10626.2  268 aa high affinity Zn transport protein 1.2e-6 ●●○○○ -1.36 -1.35781352613882
Escherichia coli M12  CO715_17095  ATI07281.1  253 aa 5'/3'-nucleotidase SurE 0.012 ●●○○○ -1.36 -1.35756910348862
Escherichia coli M12  CO715_04840  ATI05117.1  220 aa acetate CoA-transferase subunit alpha 1.7e-8 ●●○○○ -1.36 -1.35736045747437
Escherichia coli M12  CO715_04410  ATI05049.1  181 aa bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 2.4e-5 ●●○○○ -1.36 -1.35736045747437
Escherichia coli M12  CO715_00900  ATI04416.1  467 aa chromosomal replication initiator protein DnaA 4.2e-11 ●●○○○ -1.36 -1.35589993537463
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1532  AIK80152.1  37 aa hypothetical protein <1e-323 ●●○○○ -1.36 -1.3557477405871
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1121  WP_000433674.1  E8XE85  293 aa MurR/RpiR family transcriptional regulator 1.1e-8 ●●○○○ -1.36 -1.35569283456056
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4330  AIK82875.1  195 aa precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 1.1e-16 ●●○○○ -1.36 -1.35548342031724
Escherichia coli M12  CO715_11355  ATI06248.1  294 aa D-hexose-6-phosphate mutarotase 1.7e-6 ●●○○○ -1.36 -1.35548264334614
Escherichia coli M12  CO715_14340  ATI06781.1  176 aa helix-turn-helix transcriptional regulator 4.8e-24 ●●○○○ -1.35 -1.35443941327489
Escherichia coli M12  CO715_09690  ATI05955.1  105 aa ribosome silencing factor RsfS 5.1e-7 ●●○○○ -1.35 -1.35381347523214
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3313  WP_000268441.1  E8XB88  yghB  219 aa DedA family protein 0.0013 ●●○○○ -1.35 -1.35364768282294
Porphyromonas gingivalis ATCC 33277  PGN_1519  WP_005873402.1  B2RKZ3  339 aa hypothetical protein 2.0e-6 ●●○○○ -1.35 -1.35358761990164
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2644  NP_232272.2  Q9KNT6  argC  333 aa N-acetyl-gamma-glutamyl-phosphate reductase 2.9e-7 ●●○○○ -1.35 -1.35354546977365
Retrieved entries 3,101–3,200 out of 36,363 total in 565.5 ms (Link to these results)