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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1484  WP_002855360.1  A0A0H3PI57  403 aa PAS domain-containing sensor histidine kinase 0.026 ○○○○○ 2.04 2.04441314386
Mycobacterium avium subsp. paratuberculosis K10  MAP_1789  AAS04106.1  Q73Z14  235 aa hypothetical protein 0.016 ○○○○○ 2.05 2.04528728083098
Mycobacterium avium subsp. paratuberculosis K10  MAP_3976  AAS06526.1  Q73SU7  446 aa hypothetical protein 0.016 ○○○○○ 2.05 2.04541732351522
Mycobacterium avium subsp. paratuberculosis K10  MAP_2101  AAS04418.1  Q73Y56  650 aa hypothetical protein 0.016 ○○○○○ 2.05 2.0487353827861
Streptococcus pyogenes M1 5448  SP5448_00810  WP_002993834.1  159 aa V-type ATP synthase subunit K 0.047 ○○○○○ 2.05 2.04939285555513
Mycobacterium avium subsp. paratuberculosis K10  MAP_0335  AAS02652.1  Q744K6  191 aa hypothetical protein 0.016 ○○○○○ 2.05 2.05007115400421
Mycobacterium avium subsp. paratuberculosis K10  MAP_0101  AAS02418.1  Q744Y8  209 aa hypothetical protein 0.016 ○○○○○ 2.05 2.05096756896918
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0892  NP_230539.1  Q9KTL0  254 aa flagellar motor protein PomA 0.0012 ○○○○○ 2.05 2.05118486191457
Vibrio parahaemolyticus RIMD 2210633  VP_0759  BAC59022.1  Q87RL9  47 aa hypothetical protein 0.042 ○○○○○ 2.05 2.05275789997005
Mycobacterium avium subsp. paratuberculosis K10  MAP_4186  AAS06736.1  Q73S90  rplO  146 aa RplO 0.016 ○○○○○ 2.05 2.05408769535517
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1588  WP_002868828.1  A1W1K3  hisA  243 aa 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase 0.025 ○○○○○ 2.06 2.05504930531
Streptococcus pyogenes M1 5448  SP5448_01950  WP_011285688.1  300 aa ATP-binding cassette domain-containing protein 0.032 ○○○○○ 2.06 2.05612221104158
Mycobacterium avium subsp. paratuberculosis K10  MAP_3112c  AAS05660.1  Q73VA2  485 aa hypothetical protein 0.016 ○○○○○ 2.06 2.06091797832177
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0432  NP_232826.1  Q9KMD0  144 aa hypothetical protein 0.02 ○○○○○ 2.06 2.06132818345327
Acinetobacter baumannii ATCC 17978  A1S_0055  ABO10550.2  359 aa WecE protein 0.0014 ○○○○○ 2.06 2.06228607404477
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1459  WP_000100911.1  E8XI33  tppB  501 aa dipeptide/tripeptide permease DtpA 3.4e-5 ○○○○○ 2.06 2.06270185902358
Mycobacterium avium subsp. paratuberculosis K10  MAP_0133c  AAS02450.1  Q745C2  502 aa hypothetical protein 0.016 ○○○○○ 2.06 2.06270906019712
Streptococcus pyogenes M1 5448  SP5448_00205  WP_010921770.1  80 aa acyl carrier protein 0.03 ○○○○○ 2.06 2.06285156652804
Mycobacterium avium subsp. paratuberculosis K10  MAP_3878c  AAS06428.1  Q73T41  fadE7  398 aa FadE7 0.016 ○○○○○ 2.06 2.0635246408227
Mycobacterium avium subsp. paratuberculosis K10  MAP_2069c  AAS04386.1  P61186  htpG  644 aa HtpG 0.016 ○○○○○ 2.06 2.06364829163761
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1879  AIK80485.1  265 aa ribonuclease T2 family protein 1.1e-16 ○○○○○ 2.06 2.06440717664206
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3784  AIK82339.1  431 aa ribosomal RNA small subunit methyltransferase B 0.038 ○○○○○ 2.07 2.06591935630674
Serratia marcescens Strain UMH9  BVG96_10385  ASL98003.1  480 aa pyruvate kinase 0.033 ○○○○○ 2.07 2.06708347839443
Mycobacterium avium subsp. paratuberculosis K10  MAP_0270  AAS02587.1  Q745R8  fadE36  350 aa FadE36 0.015 ○○○○○ 2.07 2.06760843806974
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1233  AIK79856.1  321 aa succinylglutamate desuccinylase <1e-323 ○○○○○ 2.07 2.06771107002903
Mycobacterium avium subsp. paratuberculosis K10  MAP_2813c  AAS05130.1  Q73W47  257 aa hypothetical protein 0.015 ○○○○○ 2.07 2.0724794536529
Haemophilus influenzae Rd KW20  HI_0263  NP_438432.1  P44601  hxuB  565 aa heme/hemopexin-binding protein B 0.039 ○○○○○ 2.07 2.07372324214021
Mycobacterium avium subsp. paratuberculosis K10  MAP_2881c  AAS05198.1  Q73VY0  360 aa hypothetical protein 0.015 ○○○○○ 2.07 2.07374403350214
Mycobacterium avium subsp. paratuberculosis K10  MAP_1000c  AAS03317.1  Q741T7  kdpA  556 aa KdpA 0.015 ○○○○○ 2.07 2.07380354907183
Streptococcus pyogenes M1 5448  SP5448_00700  WP_010921808.1  290 aa Hsp33 family molecular chaperone HslO 0.035 ○○○○○ 2.08 2.07534894100288
Mycobacterium avium subsp. paratuberculosis K10  MAP_2796c  AAS05113.1  Q73W64  250 aa hypothetical protein 0.015 ○○○○○ 2.08 2.07629016328901
Mycobacterium avium subsp. paratuberculosis K10  MAP_3143  AAS05691.1  Q73V71  175 aa hypothetical protein 0.015 ○○○○○ 2.08 2.07650688269599
Acinetobacter baumannii ATCC 17978  A1S_2277  ABO12700.2  369 aa hypothetical protein 8.3e-9 ○○○○○ 2.08 2.07676973418084
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1247  AIK79870.1  136 aa hypothetical protein <1e-323 ○○○○○ 2.08 2.07866716956766
Streptococcus pyogenes M1 5448  SP5448_00260  WP_010921779.1  547 aa abortive infection protein 0.032 ○○○○○ 2.08 2.08111695999127
Vibrio parahaemolyticus RIMD 2210633  VP_0321  BAC58584.1  Q87SV1  49 aa hypothetical protein 0.04 ○○○○○ 2.08 2.08160238021332
Mycobacterium avium subsp. paratuberculosis K10  MAP_4292  AAS06842.1  Q73RY6  276 aa hypothetical protein 0.015 ○○○○○ 2.08 2.08233789848577
Mycobacterium avium subsp. paratuberculosis K10  MAP_2720c  AAS05037.1  Q73WE0  308 aa hypothetical protein 0.015 ○○○○○ 2.08 2.08354828528506
Mycobacterium avium subsp. paratuberculosis K10  MAP_2919c  AAS05236.1  Q73VU2  613 aa hypothetical protein 0.015 ○○○○○ 2.08 2.08446851514792
Mycobacterium avium subsp. paratuberculosis K10  MAP_3940c  AAS06490.1  Q73SY3  576 aa hypothetical protein 0.015 ○○○○○ 2.08 2.0846507783378
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1050  WP_002855787.1  A0A0H3PHD0  424 aa multidrug efflux RND transporter outer membrane subunit CmeD 0.024 ○○○○○ 2.09 2.08665991387
Acinetobacter baumannii ATCC 17978  A1S_1797  ABO12224.1  276 aa Aldehyde dehydrogenase 1.9e-5 ○○○○○ 2.09 2.08685233471497
Escherichia coli M12  CO715_09190  ATI05870.1  314 aa hypothetical protein 0.03 ○○○○○ 2.09 2.08947169791681
Streptococcus pyogenes M1 5448  SP5448_08330  WP_002982760.1  105 aa PTS lactose/cellobiose transporter subunit IIA 0.0088 ○○○○○ 2.09 2.09265299796805
Mycobacterium avium subsp. paratuberculosis K10  MAP_0542c  AAS02859.1  Q743P9  397 aa hypothetical protein 0.015 ○○○○○ 2.09 2.09418325372519
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0017  NP_229676.1  Q9KVX1  38 aa hypothetical protein 0.0047 ○○○○○ 2.1 2.09680810656226
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0041  NP_229700.1  Q9KVU8  218 aa hypothetical protein 0.00031 ○○○○○ 2.1 2.09859229674261
Mycobacterium avium subsp. paratuberculosis K10  MAP_1420  AAS03737.1  Q740D1  6384 aa hypothetical protein 0.014 ○○○○○ 2.11 2.10515331144348
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1649  AIK80269.1  187 aa bacterial regulatory, tetR family protein 1.1e-16 ○○○○○ 2.11 2.10651151731794
Mycobacterium avium subsp. paratuberculosis K10  MAP_3935  AAS06485.1  Q73SY7  241 aa hypothetical protein 0.014 ○○○○○ 2.11 2.11091085429255
Mycobacterium avium subsp. paratuberculosis K10  MAP_3711c  AAS06261.1  Q73TK7  200 aa hypothetical protein 0.014 ○○○○○ 2.11 2.11222941467973
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1604  WP_002856411.1  A0A0H3PA76  268 aa ABC transporter substrate-binding protein 0.022 ○○○○○ 2.11 2.11360249212
Streptococcus pyogenes M1 5448  SP5448_04360  WP_011285584.1  274 aa helix-turn-helix transcriptional regulator 0.015 ○○○○○ 2.11 2.11380240092547
Streptococcus pyogenes M1 5448  SP5448_04360  WP_011285583.1  52 aa hypothetical protein 0.015 ○○○○○ 2.11 2.11380240092547
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0314  WP_002872030.1  A0A0H3PEG0  lpxB  364 aa lipid-A-disaccharide synthase 0.022 ○○○○○ 2.11 2.114082684
Mycobacterium avium subsp. paratuberculosis K10  MAP_3796  AAS06346.1  Q73TC2  219 aa hypothetical protein 0.014 ○○○○○ 2.11 2.11477367084316
Mycobacterium avium subsp. paratuberculosis K10  MAP_4103c  AAS06653.1  Q73SH1  280 aa hypothetical protein 0.014 ○○○○○ 2.12 2.11629288243113
Vibrio parahaemolyticus RIMD 2210633  VP_0009  BAC58272.1  Q87TQ9  49 aa hypothetical protein 0.037 ○○○○○ 2.12 2.11709201385033
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1033  AIK79656.1  129 aa phenylacetic acid degradation protein PaaD 2.3e-12 ○○○○○ 2.12 2.11898507650468
Streptococcus pyogenes M1 5448  SP5448_06050  WP_011285488.1  230 aa orotidine-5'-phosphate decarboxylase 0.024 ○○○○○ 2.12 2.11957041991386
Escherichia coli M12  CO715_01975  ATI04607.1  138 aa thiamin phosphate synthase 2.4e-6 ○○○○○ 2.12 2.12055995403989
Vibrio parahaemolyticus RIMD 2210633  VP_1581  BAC59845.1  Q877N6  42 aa hypothetical protein 0.037 ○○○○○ 2.12 2.12060464609423
Acinetobacter baumannii ATCC 17978  A1S_2617  ABO13034.2  A3M7Z0  serC  359 aa 3-phosphoserine aminotransferase 4.3e-6 ○○○○○ 2.12 2.12212985366386
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0471  WP_030123215.1  A0A0H3PET5  684 aa TonB-dependent receptor 0.022 ○○○○○ 2.12 2.12293167154
Mycobacterium avium subsp. paratuberculosis K10  MAP_1983c  AAS04300.1  Q73YH3  cobC  356 aa CobC 0.014 ○○○○○ 2.12 2.12387293212082
Mycobacterium avium subsp. paratuberculosis K10  MAP_0693  AAS03010.1  Q742Z2  287 aa hypothetical protein 0.014 ○○○○○ 2.13 2.12769899505135
Mycobacterium avium subsp. paratuberculosis K10  MAP_3289c  AAS05839.1  Q73US7  mce1  441 aa Mce1_1 0.014 ○○○○○ 2.13 2.12887282562963
Mycobacterium avium subsp. paratuberculosis K10  MAP_2753  AAS05070.1  Q73WA7  252 aa hypothetical protein 0.014 ○○○○○ 2.13 2.13103320728841
Mycobacterium avium subsp. paratuberculosis K10  MAP_0783c  AAS03100.1  Q742Q2  kdc  563 aa Pdc 0.013 ○○○○○ 2.13 2.13119231531785
Acinetobacter baumannii ATCC 17978  A1S_2716  ABO13129.2  398 aa dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) 0.0096 ○○○○○ 2.13 2.13398266086044
Vibrio parahaemolyticus RIMD 2210633  VP_2651  BAC60914.1  Q87LG1  45 aa hypothetical protein 0.036 ○○○○○ 2.14 2.13523018854184
Mycobacterium avium subsp. paratuberculosis K10  MAP_3852c  AAS06402.1  Q73T67  195 aa hypothetical protein 0.013 ○○○○○ 2.14 2.14086144637901
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1074  AIK79697.1  268 aa NLPA lipofamily protein <1e-323 ○○○○○ 2.14 2.14114925087268
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0532  WP_002855142.1  A0A0H3PEH2  288 aa Gfo/Idh/MocA family oxidoreductase 0.021 ○○○○○ 2.14 2.14269059264
Mycobacterium avium subsp. paratuberculosis K10  MAP_1632c  AAS03949.1  Q73ZH1  455 aa hypothetical protein 0.013 ○○○○○ 2.15 2.14678303185925
Mycobacterium avium subsp. paratuberculosis K10  MAP_3595  AAS06145.1  Q73TX3  305 aa hypothetical protein 0.013 ○○○○○ 2.15 2.14745982624813
Mycobacterium avium subsp. paratuberculosis K10  MAP_3596c  AAS06146.1  Q73TX2  adhE  363 aa AdhE 0.013 ○○○○○ 2.15 2.14745982624813
Streptococcus pyogenes M1 5448  SP5448_07645  WP_010921962.1  117 aa DUF3397 domain-containing protein 0.021 ○○○○○ 2.15 2.15033318785193
Streptococcus pyogenes M1 5448  SP5448_02900  WP_010922536.1  213 aa response regulator transcription factor 0.024 ○○○○○ 2.15 2.15033318785193
Mycobacterium avium subsp. paratuberculosis K10  MAP_1248  AAS03565.1  Q740U4  dinX  463 aa DinX 0.013 ○○○○○ 2.15 2.15371852521183
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1047  WP_002853564.1  A0A0H3PAK1  ctsW  191 aa ComF family protein 0.02 ○○○○○ 2.16 2.15665989951
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1056  NP_233438.1  Q9KKP6  770 aa methyl-accepting chemotaxis protein 0.039 ○○○○○ 2.16 2.15947518644897
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1243  AIK79866.1  495 aa binding-protein-dependent transport system innermembrane component family protein 1.2e-9 ○○○○○ 2.16 2.15983920559444
Mycobacterium avium subsp. paratuberculosis K10  MAP_2188c  AAS04505.1  Q73XX0  514 aa hypothetical protein 0.013 ○○○○○ 2.16 2.16278912529681
Mycobacterium avium subsp. paratuberculosis K10  MAP_3303  AAS05853.1  Q73UR3  lipV  261 aa LipV 0.013 ○○○○○ 2.16 2.16475852004693
Mycobacterium avium subsp. paratuberculosis K10  MAP_2500  AAS04817.1  Q73X10  634 aa hypothetical protein 0.013 ○○○○○ 2.17 2.16538212199251
Escherichia coli M12  CO715_24240  ATI08547.1  266 aa EEP domain-containing protein 0.037 ○○○○○ 2.17 2.16667072318889
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1250  AIK79873.1  326 aa NAD(P)H quinone oxidoreductase, PIG3 family protein <1e-323 ○○○○○ 2.17 2.16740717319778
Mycobacterium avium subsp. paratuberculosis K10  MAP_2567c  AAS04884.1  Q73WU3  tagA  193 aa TagA 0.012 ○○○○○ 2.17 2.16865916116076
Acinetobacter baumannii ATCC 17978  A1S_1976  ABO12403.1  A3M659  rimO  447 aa hypothetical protein 0.00089 ○○○○○ 2.17 2.17120126241766
Acinetobacter baumannii ATCC 17978  A1S_1544  ABO11971.2  345 aa fructose-16-bisphosphate aldolase, class II 0.0073 ○○○○○ 2.17 2.17146701770596
Mycobacterium avium subsp. paratuberculosis K10  MAP_1144c  AAS03461.1  Q741E7  488 aa hypothetical protein 0.012 ○○○○○ 2.17 2.1727675121571
Streptococcus pyogenes M1 5448  SP5448_02680  WP_011285663.1  88 aa bacteriocin immunity protein 0.044 ○○○○○ 2.17 2.17436660030355
Mycobacterium avium subsp. paratuberculosis K10  MAP_2866c  AAS05183.1  Q73VZ5  412 aa hypothetical protein 0.012 ○○○○○ 2.18 2.17513758177717
Mycobacterium avium subsp. paratuberculosis K10  MAP_0914c  AAS03231.1  Q742C3  573 aa hypothetical protein 0.012 ○○○○○ 2.18 2.17665530643485
Vibrio parahaemolyticus RIMD 2210633  VP_1004  BAC59267.1  Q87QZ4  54 aa conserved hypothetical protein 0.032 ○○○○○ 2.18 2.1779639220548
Mycobacterium avium subsp. paratuberculosis K10  MAP_0105c  AAS02422.1  Q745A6  889 aa hypothetical protein 0.012 ○○○○○ 2.18 2.18157981253202
Escherichia coli M12  CO715_20255  ATI07849.1  106 aa phosphate starvation-inducible protein PsiF 1.4e-95 ○○○○○ 2.18 2.18190188222906
Mycobacterium avium subsp. paratuberculosis K10  MAP_2518  AAS04835.1  Q73WZ2  409 aa hypothetical protein 0.012 ○○○○○ 2.18 2.18232141648275
Mycobacterium avium subsp. paratuberculosis K10  MAP_2778c  AAS05095.1  Q73W82  225 aa hypothetical protein 0.012 ○○○○○ 2.19 2.1906734338533
Retrieved entries 35,801–35,900 out of 36,363 total in 1389.4 ms (Link to these results)